The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Antimicrobial and antiviral activities of polyphenolics from Cocos nucifera Linn. (Palmae) husk fiber extract
Open accessAbstract
The decoction of Cocos nucifera L. husk fiber has been used in northeastern Brazil traditional medicine for treatment of diarrhea and arthritis. Water extract obtained from coconut husk fiber and fractions from adsorption chromatography revealed antimicrobial activity against Staphylococcus aureus. The crude extract and one of the fractions rich in catechin also showed inhibitory activity against acyclovir-resistant herpes simplex virus type 1 (HSV-1-ACVr). All fractions were inactive against the fungi Candida albicans, Fonsecaea pedrosoi and Cryptococcus neoformans. Catechin and epicatechin together with condensed tannins (B-type procyanidins) were demonstrated to be the components of the water extract.
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In the citing paper
“Cellular studies have also shown that monolaurin exhibits antiviral and antifungal activity [78].”
From Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils (2017) · cites this paper as [78]
In the citing paper
“Meneguetti et al. (2017) and Esquenazi et al. (2002) reported the presence of several phenolic compounds in coconut including Catechin and salicylic acid in the CW and gallic, caffeic, salicylic, and p-coumaric acids in the meat.”
From The use of High-Pressure Processing (HPP) to improve the safety and quality of raw coconut (Cocos nucifera L) water (2020) · cites this paper as Esquenazi et al. (2002)
In the citing paper
“Others have reported antiviral and antibacterial activities due to the presence of lauric acid and other antimicrobial components (Cruz et al., 2014;Esquenazi et al., 2002;Meneguetti et al., 2017;Sarika and Rai, 2012;Sheri et al., 2006).”
From The use of High-Pressure Processing (HPP) to improve the safety and quality of raw coconut (Cocos nucifera L) water (2020) · cites this paper as Esquenazi et al., 2002
In the citing paper
“In Brazil, extract from the husk fiber of C. nucifera is used to treat diarrhea (7).”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [7]
In the citing paper
“The antifungal, antimicrobial, and antiviral effects were attributed to condensed tannins and catechins present in the crude extract and fractions II-V, especially fraction II, which had a higher concentration of these compounds.”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [7]
In the citing paper
“Antiviral action was only seen with the crude extract and fraction II.”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [7]
In the citing paper
“Antifungal activity was demonstrated as growth inhibition of Candida albicans, Cryptococcus neoformans or Fonsecaea pedrosoi.”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [7]
In the citing paper
“The lyophilized extract and fractions, as well as ethyl acetate extracts, from the C. nucifera fiber are rich in polyphenols, compounds such as catechins, epicatechins, tannins, and flavonoids (7,33–35).”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [7]
In the citing paper
“In studies with crude extract and five TLC fractions (I-V) of fiber mesocarp of C. nucifera fruit, in vitro antimicrobial activity was seen in all trial strains of S. aureus tested with fractions II-V (7).”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [7]
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Metadata
- Authors
- Esquenazi, D., Wigg, M. D., Miranda, M. M. F. S., Rodrigues, H. M., Tostes, J. B. F., Rozental, S., da Silva, A. J. R., & Alviano, C. S.
- Affiliations
- Universidade Federal do Rio de Janeiro (BR)
- Corresponding author
- Esquenazi, Daniele
- ORCID
- Alviano, Celuta S.
- Venue
- Research in Microbiology
- Publisher
- Elsevier BV
- Published
- 2002-12
- Volume
- 153
- Issue
- 10
- Pages
- 647-652
- ISSN
- 0769-2609 (ISSN-L)
- 0923-2508
- OpenAlex
- W2073056737
- Cited by
- 291
- References
- 36
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 7 · 2023: 20 · 2022: 19 · 2021: 18 · 2020: 17 · 2019: 17 · 2018: 18 · 2017: 9 · 2016: 18 · 2015: 16 · 2014: 7 · 2013: 15 · 2012: 17
- FWCI
- 2.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Research in Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Coconut Research and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Keywords
- Cocos nucifera, coconut husk fiber, polyphenols, catechins, epicatechin, procyanidins, proanthocyanidins, antimicrobial activity, antiviral activity, Staphylococcus aureus, herpes simplex virus type 1, acyclovir resistance, Candida albicans, Fonsecaea pedrosoi, Cryptococcus neoformans, traditional medicine, decoction
- MeSH terms
- Animals, Anti-Infective Agents, Anti-Bacterial Agents, Antiviral Agents, Catechin, Chlorocebus aethiops, Chromatography, High Pressure Liquid, Cocos, Flavonoids, Humans, Phenols, Plant Extracts, Polymers, Staphylococcus aureus, Vero Cells, Herpesvirus 1, Human
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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