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Cited by 101Cardiovascular and exercise physiologyExercise and Physiological ResponsesPhysical Activity and Health

Physical stress and catecholamine release

Kjær, M., Secher, N.H., Galbo, H.·1987·Baillière's Clinical Endocrinology and Metabolism
DOI 10.1016/s0950-351x(87)80064-2
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Abstract

In both health and disease, noradrenaline and adrenaline concentrations in plasma increase with intensity and duration of exercise (Figure 1). These changes are only to a minor extent due to decreased catecholamine clearance (Figure 2). The increase in sympathoadrenal activity during exercise is primarily elicited by feed-forward stimulation from motor centres in the brain (Figure 3, Table 1), and by afferent impulses from working muscles (Figure 4). During continued exercise, changes in internal milieu may enhance the catecholamine response. Of particular interest from a metabolic point of view is the fact that during exercise a decrease in plasma glucose causes a relatively large increase in plasma adrenaline (Figure 5). Sympathoadrenal activity is of major importance for exercise capacity. By depressing insulin secretion, as well as by direct effects on target tissues, sympathoadrenal activity enhances mobilization of glycogen as well as triglyceride from both extra- and intramuscular depots. After training, noradrenaline responses to given absolute work loads are reduced, while responses to given relative loads, i.e. work load in percent of individual work capacity, VO2/VO2max%, are unchanged. Prolonged endurance training may increase the size and secretory capacity of the adrenal medulla (Figure 7, Table 2), an adaptation which may improve exercise capacity. Differences in catecholamine levels cannot explain the fact that physically-active individuals have a lower cardia…

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  • Exerkines are not only cytokines; hormones, neurotransmitters and metabolites associated with exercise, such as catecholamines, lactate and free fatty acids, can also act as exerkines with endocrine signalling potential.

    “Exerkines are not merely cytokines, however, as hormones, neurotransmitters or metabolites associated with exercise, such as catecholamines40, lactate41 or FFAs29, can also serve as exerkines with endocrine signalling potential42.”

    From Exerkines in health, resilience and disease (2022) · cites this paper as [40]

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Authors
Kjær, M., Secher, N. H., & Galbo, H.
ORCID
Venue
Baillière's Clinical Endocrinology and Metabolism
Publisher
Elsevier BV
Published
1987-05
Volume
1
Issue
2
Pages
279-298
ISSN
0950-351X (ISSN-L)
DOI
10.1016/s0950-351x(87)80064-2
OpenAlex
W2081975007
Cited by
101
References
59
Citations by year
2026: 1 · 2025: 4 · 2024: 8 · 2023: 1 · 2022: 4 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 6 · 2015: 3 · 2014: 1 · 2013: 3 · 2012: 3
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Baillière s Clinical Endocrinology and Metabolism (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
Keywords
catecholamines, norepinephrine, epinephrine, physical activity, sympathoadrenal activity, plasma glucose, insulin secretion, glycogen mobilization, triglyceride mobilization, endurance training, adrenal medulla, exercise capacity, cardiac mortality
MeSH terms
Animals, Catecholamines, Energy Metabolism, Physical Exertion, Humans

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