Mediated biosensors
Abstract
Direct electrode transfer between enzyme and the electrode in biosensors requires high efficiency therefore, synthetic replacement for oxygen led to the development of enzyme mediators and modified electrodes in biosensor fabrication. In this context, a number of electron acceptors and complexes have been used. Present paper gives an overview of various methodologies involved in the mediated systems, their merits and wide applications.
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Electrochemical glucose sensors can be divided into potentiometric, amperometric, or conductometric.
“Electrochemical glucose sensors can be divided into potentiometric (employed to detect variations of surface charge onto a counter electrode), amperometric (charge flow between the counter electrode and the bio-system), or conductometric (variations in ionic conductance between electrodes) 74,75.”
From Glucose biosensors in clinical practice: principles, limits and perspectives of currently used devices (2022) · cites this paper as [74]
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Electrochemical Biosensors - Sensor Principles and Architectures
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Sensor and biosensor preparation, optimisation and applications of Prussian Blue modified electrodes
Ricci, F., & Palleschi, G. (2005) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2004.12.001 · Cited by 781 · see citing works
Wearable Electrochemical Glucose Sensors in Diabetes Management: A Comprehensive Review
Saha, T., Del Caño, R., Mahato, K., De la Paz, E., Chen, C., Ding, S., Yin, L., & Wang, J. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00078 · Cited by 442 · see citing works
Pullano, S. A., Greco, M., Bianco, M. G., Foti, D., Brunetti, A., & Fiorillo, A. S. (2022) · Theranostics · doi:10.7150/thno.64035 · Cited by 210 · see citing works
“Electrochemical glucose sensors can be divided into potentiometric (employed to detect variations of surface charge onto a counter electrode), amperometric (charge flow between the counter electrode and the bio-system), or conductometric (variations in ionic conductance between electrodes) [74,75].”
BackgroundNgoepe, M., Choonara, Y., Tyagi, C., Tomar, L., Du Toit, L., Kumar, P., Ndesendo, V., & Pillay, V. (2013) · Sensors · doi:10.3390/s130607680 · Cited by 92 · see citing works
Pillai, S., Upadhyay, A., Sayson, D., Nguyen, B. H., & Tran, S. D. (2021) · Molecules · doi:10.3390/molecules27010165 · Cited by 95 · see citing works
- Authors
- Chaubey, A., & Malhotra, B. D.
- Affiliations
- CSIR National Physical Laboratory of India (IN)
- Corresponding author
- Chaubey, Asha
- Venue
- Biosensors and Bioelectronics
- Publisher
- Elsevier BV
- Published
- 2002-06
- Volume
- 17
- Issue
- 6-7
- Pages
- 441-456
- ISSN
- 0956-5663 (ISSN-L)
- OpenAlex
- W4211072042
- Cited by
- 777
- References
- 0
- Citations by year
- 2026: 24 · 2025: 34 · 2024: 45 · 2023: 37 · 2022: 42 · 2021: 41 · 2020: 48 · 2019: 40 · 2018: 46 · 2017: 43 · 2016: 33 · 2015: 30 · 2014: 34 · 2013: 34 · 2012: 27
- FWCI
- 3.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biosensors and Bioelectronics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Enzyme Catalysis and Immobilization
- Physical Sciences › Chemistry › Electrochemistry › Electrochemical Analysis and Applications
- Keywords
- modified electrode, electron transfer, electron acceptors, enzyme-electrode interface, biosensor fabrication
- MeSH terms
- Catalysis, Electrochemistry, Electrodes, Electron Transport, Enzymes, Immobilized, Models, Chemical, Oxidation-Reduction, Biosensing Techniques
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