CoChat
Sign Up
Cited by 191Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model OrganismsNuclear Structure and Function

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Telomeres and senescence: The history, the experiment, the future

Open access
Greider, Carol W.·1998·Current Biology
DOI 10.1016/s0960-9822(98)70105-8
Open this paper in CoChat — free accountOpen PDF

Abstract

Telomere length has been proposed to signal entry into cellular senescence. Expression of the human telomerase subunit, hTERT, in primary cells now shows that these cells bypass senescence.

Overview

Integrity signals

Registry

Crossref · 10.1016/s0960-9822(98)70105-8

Cites

12 of 12 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 21

  1. Witkowski, 1985, The myth of cell immortality, Trends Biochem Sci, 10, 258, 10.1016/0968-0004(85)90076-3 · DOI
  2. Hayflick, 1961, The serial cultivation of human diploid strains, Exp Cell Res, 25, 585, 10.1016/0014-4827(61)90192-6 · DOI · Paper page
  3. Hayflick, 1965, The limited in vitro lifetime of human diploid strains, Exp Cell Res, 37, 614, 10.1016/0014-4827(65)90211-9 · DOI · Paper page
  4. Campisi, 1996, Replicative senescence: an old lives' tale?, Cell, 84, 497, 10.1016/S0092-8674(00)81023-5 · DOI
  5. Olovnikov, 1996, Telomeres, telomerase, and aging: origin of the theory, Exp Gerontol, 31, 443, 10.1016/0531-5565(96)00005-8 · DOI · Paper page
  6. Olovnikov, 1973, A theory of marginotomy, J Theor Biol, 41, 181, 10.1016/0022-5193(73)90198-7 · DOI
  7. Blackburn, 1978, A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena, J Mol Biol, 120, 33, 10.1016/0022-2836(78)90294-2 · DOI · Paper page
  8. Greider, 1985, Identification of a specific telomere terminal transferase activity in Tetrahymena extracts, Cell, 43, 405, 10.1016/0092-8674(85)90170-9 · DOI · Paper page
  9. Moyzis, 1988, A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes, Proc Natl Acad Sci USA, 85, 6622, 10.1073/pnas.85.18.6622 · DOI
  10. Hastie, 1990, Telomere reduction in human colorectal carcinoma and with ageing, Nature, 346, 866, 10.1038/346866a0 · DOI · Paper page
  11. Lingner, 1996, Purification of telomerase from Euplotes aediculatus: requirement of a primer 3′ overhang, Proc Natl Acad Sci USA, 93, 10712, 10.1073/pnas.93.20.10712 · DOI
  12. Lendvay, 1996, Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes, Genetics, 144, 1399, 10.1093/genetics/144.4.1399 · DOI
  13. Lingner, 1997, Reverse transcriptase motifs in the catalytic subunit of telomerase, Science, 276, 561, 10.1126/science.276.5312.561 · DOI · Paper page
  14. Nakamura, 1997, Telomerase catalytic subunit homologs from fission yeast and human, Science, 277, 955, 10.1126/science.277.5328.955 · DOI · Paper page
  15. Meyerson, 1997, hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization, Cell, 90, 785, 10.1016/S0092-8674(00)80538-3 · DOI · Paper page
  16. Harrington, 1997, Human telomerase contains evolutionarily conserved catalytic and structural subunits, Genes Dev, 11, 3109, 10.1101/gad.11.23.3109 · DOI · Paper page
  17. Kilian, 1997, Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types, Hum Mol Genet, 6, 2011, 10.1093/hmg/6.12.2011 · DOI
  18. Weinrich, 1997, Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT, Nat Genet, 17, 498, 10.1038/ng1297-498 · DOI
  19. Nakayama, 1998, Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas, Nat Genet, 18, 65, 10.1038/ng0198-65 · DOI
  20. Starling, 1990, Extensive telomere repeat arrays in mouse are hypervarible, Nucleic Acid Res, 18, 6881, 10.1093/nar/18.23.6881 · DOI
  21. Zijlmans, 1997, Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats, Proc Natl Acad Sci USA, 94, 7423, 10.1073/pnas.94.14.7423 · DOI

Cited by

Sorted by citations

Metadata

Authors
Greider, C. W.
Affiliations
Johns Hopkins University (US)
Corresponding author
Greider, Carol W.
ORCID
Greider, Carol W.
Venue
Current Biology
Publisher
Elsevier BV
Published
1998-02
Volume
8
Issue
5
Pages
R178-R181
ISSN
0960-9822 (ISSN-L)
DOI
10.1016/s0960-9822(98)70105-8
OpenAlex
W1993152080
Cited by
191
References
12
Citations by year
2025: 9 · 2024: 7 · 2023: 9 · 2022: 3 · 2021: 2 · 2020: 6 · 2019: 4 · 2018: 6 · 2017: 4 · 2016: 3 · 2015: 5 · 2014: 4 · 2013: 6 · 2012: 5
FWCI
2.75
Type
journal article
Language
en
Open access
Licence
Locations
  • Current Biology (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
National Institutes of Health
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Structure and Function
Keywords
telomeres, cellular senescence, telomere length, hTERT, telomerase, senescence bypass, primary cells, aging
MeSH terms
Aging, Animals, Humans, Telomere, Telomerase

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review