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Plasma protein (albumin) catabolism by the tumor itself—implications for tumor metabolism and the genesis of cachexia
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“However, there is evidence in rapidly proliferating cells in cancer that serum albumin can be transported into cells and cell organelles, where it can be degraded to its component amino acids acting as building blocks.84, 85, 86, 87, 88”
From Hypoalbuminemia: Pathogenesis and Clinical Significance (2019) · cites this paper as [85]
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Metadata
- Authors
- Stehle, G., Sinn, H., Wunder, A., Schrenk, H. H., Stewart, J. C. M., Hartung, G., Maier-Borst, W., & Heene, D. L.
- Affiliations
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- Corresponding author
- Stehle, Gerd
- Venue
- Critical Reviews in Oncology/Hematology
- Publisher
- Elsevier BV
- Published
- 1997-07
- Volume
- 26
- Issue
- 2
- Pages
- 77-100
- ISSN
- 1040-8428 (ISSN-L)
- OpenAlex
- W2066742760
- Cited by
- 305
- References
- 250
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 15 · 2023: 17 · 2022: 16 · 2021: 30 · 2020: 16 · 2019: 24 · 2018: 21 · 2017: 18 · 2016: 16 · 2015: 13 · 2014: 14 · 2013: 13 · 2012: 16
- FWCI
- 0.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Oncology/Hematology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Interaction Studies and Fluorescence Analysis
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Health Sciences › Medicine › Oncology › Metal complexes synthesis and properties
- Keywords
- human serum albumin, metal-based drugs, platinum drugs, gold-based drugs, cancer metabolism, cachexia, albumin catabolism, plasma half-life
- MeSH terms
- Animals, Blood Proteins, Cachexia, Energy Metabolism, Humans, Liver, Lysosomes, Models, Biological, Neoplasms, Nitrogen, Oxygen Consumption, Serum Albumin
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