Endocrine and Metabolic Abnormalities in Adolescents with a PCOS-like Condition: Consequences for Adult Reproduction
Abstract
The polycystic ovary syndrome (PCOS) has a perimenarcheal onset. Increased luteinizing hormone (LH) and androgen concentrations are common among anovulatory adolescents and some also have hyperinsulinemia. Many will later have normal ovulatory cycles, whereas others with several co-existing abnormalities will develop full-blown PCOS with menstrual cycle irregularities and infertility in adulthood.
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In a study of unselected schoolgirls with oligomenorrhea, 4% had hirsutism and 57% had elevated testosterone levels.
“In a study of unselected schoolgirls with oligomenorrhea, 4% had hirsutism and 57% had elevated testosterone levels [58]”
From The Diagnosis of Polycystic Ovary Syndrome during Adolescence (2015) · cites this paper as [58]
Cites
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- Authors
- Apter, D.
- Affiliations
- Väestöliitto (FI)
- Corresponding author
- Apter, Dan
- ORCID
- Apter, Dan
- Venue
- Trends in Endocrinology & Metabolism
- Publisher
- Elsevier BV
- Published
- 1998-02
- Volume
- 9
- Issue
- 2
- Pages
- 58-61
- ISSN
- 1043-2760 (ISSN-L)
- OpenAlex
- W2028948219
- Cited by
- 56
- References
- 22
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 5 · 2021: 1 · 2020: 4 · 2019: 4 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 6 · 2014: 6 · 2013: 2 · 2012: 1
- FWCI
- 0.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Endocrinology and Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- polycystic ovary syndrome, adolescents, luteinizing hormone, androgens, hyperinsulinemia, anovulation, menstrual irregularity, reproductive outcomes
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