Structural insights into DNA polymerase β fidelity: hold tight if you want it right

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DNA Structure and Aspartate 276 Influence Nucleotide Binding to Human DNA Polymerase β

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A Water-Mediated and Substrate-Assisted Catalytic Mechanism forSulfolobus solfataricusDNA Polymerase IV

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DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State

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DNA Polymerase β Ribonucleotide Discrimination

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DNA Polymerase and Mammalian Base Excision RepairPreprint

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Incorporation of Gemcitabine and Cytarabine into DNA by DNA Polymerase β and Ligase III/XRCC1

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Is there adequate ionization mechanism of the spontaneous transitions? Quantum-chemical investigation

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Exploring the role of large conformational changes in the fidelity of DNA polymerase β

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Escherichia coli DNA Polymerase I (Klenow Fragment) Uses a Hydrogen-bonding Fork from Arg668 to the Primer Terminus and Incoming Deoxynucleotide Triphosphate to Catalyze DNA Replication

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Involvement of Phenylalanine 272 of DNA Polymerase Beta in Discriminating between Correct and Incorrect Deoxynucleoside Triphosphates

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Base excision repair and design of small molecule inhibitors of human DNA polymerase β

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Structure/Function Analysis of the Interaction of Adenomatous Polyposis Coli with DNA Polymerase β and Its Implications for Base Excision Repair

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Rapid Segmental and Subdomain Motions of DNA Polymerase β

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Elementary Molecular Mechanisms of the Spontaneous Point Mutations in DNA: A Novel Quantum-Chemical Insight into the Classical Understanding

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The Effect of DNA Structure on the Catalytic Efficiency and Fidelity of Human DNA Polymerase β on Templates with Platinum-DNA Adducts

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Nucleotide Selectivity Opposite a Benzo[a]pyrene-Derived N2-dG Adduct in a Y-Family DNA Polymerase: A 5′-Slippage Mechanism

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DNA Repair Patch-mediated Double Strand DNA Break Formation in Human Cells

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DNA Lesion Bypass Polymerases Open Up

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Kinetic Analysis of 3′–5′ Nucleotide Addition Catalyzed by Eukaryotic tRNAHis Guanylyltransferase

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Differing Conformational Pathways Before and After Chemistry for Insertion of dATP versus dCTP Opposite 8-OxoG in DNA Polymerase β

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Fidelity Mechanisms of DNA Polymerase β

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A specific N-terminal extension of the 8 kDa domain is required for DNA end-bridging by human Polµ and Polλ

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Systematic biochemical analysis of somatic missense mutations in DNA polymerase β found in prostate cancer reveal alteration of enzymatic function

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I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity

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In Silico Studies of the African Swine Fever Virus DNA Polymerase X Support an Induced-Fit Mechanism

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Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase

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Further Quantum Mechanical Evidence that Difluorotoluene Does Not Hydrogen Bond

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Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1

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Solution structures of a duplex containing an adenine opposite a gap (absence of one nucleotide)

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RNA Probes of Steric Effects in Active Sites: High Flexibility of HIV-1 Reverse Transcriptase

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DNA polymerases lose their grip.

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Insertion of oxidized nucleotide triggers rapid DNA polymerase opening

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Covalent Polycyclic Aromatic Hydrocarbon–DNA Adducts: Carcinogenicity, Structure, and Function

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The Sole DNA Ligase in Entamoeba histolytica Is a High-Fidelity DNA Ligase Involved in DNA Damage Repair

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Does non-empirical quantum chemistry allow understanding nature of purine-purine mismatches formation by high fidelity DNA polymerases?

Kochina, O. S., Yurenko, Y. P., & Hovorun, D. М. (2007) · Biopolymers and Cell · doi:10.7124/bc.000763 · Cited by 6 · see citing works

Novel Engineering Approaches for DNA Sequencing and Analysis

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Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms

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Chemical reactions catalyzed by DNA polymerases

Krayevsky, A. A. (2000) · Russian Journal of Bioorganic Chemistry · doi:10.1007/bf02758854 · Cited by 1 · see citing works

Impact of Site-Specific Benzo[a]Pyrene Diol Epoxide-dG Lesions at or near Single/Double-Strand DNA Junctions on DNA Bending

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Variations of Human DNA Polymerase Genes as Biomarkers of Prostate Cancer Progression

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Paper alert

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Structural Insights into the Origins of DNA Polymerase Fidelity

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DNA Polymerase β: Pre-Steady-State Kinetic Analysis and Roles of Arginine-283 in Catalysis and Fidelity

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DNA polymerase β nucleotide-stabilized template misalignment fidelity depends on local sequence context

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DNA pol in action

Moorefield, B. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2651

Loss of DNA Polymerase β Stacking Interactions with Templating Purines, but Not Pyrimidines, Alters Catalytic Efficiency and Fidelity

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