How Taxol® stabilises microtubule structure

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Challenges in the chemotherapy of Chagas disease: Looking for possibilities related to the differences and similarities between the parasite and host

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Microtubules as Regulators of Neural Network Shape and Function: Focus on Excitability, Plasticity and Memory

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Intranasal Paclitaxel Alters Alzheimer’s Disease Phenotypic Features in 3xTg-AD Mice

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Quantitative proteomic analysis of ovarian cancer cells identified mitochondrial proteins associated with paclitaxel resistance

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Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites

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Genetic Evidence for Interaction between η- and β-Tubulins

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Structural basis for the action of drugs that affect microtubule dynamics

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Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A

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Role of paclitaxel on critical nucleation concentration of tubulin and its effects thereof

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Paclitaxel inhibits natural killer cell binding to target cells by down-regulating adhesion molecule expression.

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Damaging Effect of Taxol on Mouse Spermatogenesis

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Protein fishing with chiral molecular baits

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The electrical properties of isolated microtubules

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Cryo-ET suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules

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The Key Residues of Active Sites on the Catalytic Fragment for Paclitaxel Interacting with Poly (ADP-Ribose) Polymerase

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Calcium–axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes

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The Molecular Perspective: Microtubules and the Taxanes

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Natural Product-Derived Drugs: Structural Insights into Their Biological Mechanisms

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Mechanical Aspects of Microtubule Bundling in Taxane-Treated Circulating Tumor Cells

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DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells.

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Pharmacological Inhibition of PP2A Overcomes Nab-Paclitaxel Resistance by Downregulating MCL1 in Esophageal Squamous Cell Carcinoma (ESCC)

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Molecular Basis for Fungal Selectivity of Novel Antimitotic Compounds

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Preparation of Peppermint Oil-Based Nanodevices Loaded with Paclitaxel: Cytotoxic and Apoptosis Studies in HeLa Cells

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A facile route to paclitaxel C-10 carbamates

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The effect of p53 gene expression on the inhibition of cell proliferation by paclitaxel

Sakashita, F., Osada, S., Takemura, M., Imai, H., Tomita, H., Nonaka, K., Takahashi, T., & Seishima, M. (2007) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-007-0614-5 · Cited by 8

Helical alignment inversion of microtubules in accordance with a structural change in their lattice

Shikinaka, K., Mori, S., Shigehara, K., & Masunaga, H. (2015) · Soft Matter · doi:10.1039/c5sm00488h · Cited by 7

Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners

Nadaradjane, C., Yang, C. H., Rodriguez‐Gabin, A., Ye, K. Q., Sugasawa, K., Atasoylu, O., Smith, A. B., Horwitz, S. B., & McDaid, H. M. (2018) · Journal of Natural Products · doi:10.1021/acs.jnatprod.8b00111 · Cited by 7

4.6 Tubulin and Microtubule Structure: Mechanistic Insights into Dynamic Instability and Its Biological Relevance

Nogales, E., & Alushin, G. M. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-374920-8.00407-0 · Cited by 7

Cryo-electron tomography suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubulesPreprint

Chakraborty, S., Martínez-Sánchez, A., Beck, F., Toro‐Nahuelpan, M., Hwang, I.-Y., Noh, K., Baumeister, W. P., & Mahamid, J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.28.501854 · Cited by 7

Antibacterial activities of viriditoxin congeners and synthetic analogues against fish pathogens

Noh, T. H., Sen, L., Hong, J., Lee, J., Moon, H. R., & Jung, J. H. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.10.015 · Cited by 6

Brain Microtubule Electrical Oscillations-Empirical Mode Decomposition Analysis

Scarinci, N., Priel, A., Cantero, M. D. R., & Cantiello, H. F. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01290-9 · Cited by 6

Identification of Leads from Marine Seaweeds against Human β-tubulin

Selvaa Kumar, C., Gadewal, N., & Mohammed, S. M. M. (2012) · Letters in Drug Design & Discovery · doi:10.2174/1570180811309010067 · Cited by 5

Molecular Mechanisms of Microtubule Acting Cancer Drugs

Correia, J. J., & Lobert, S. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-336-3_2 · Cited by 6

β3 accelerates microtubule plus end maturation through a divergent lateral interface

Wood, L. M., & Moore, J. K. (2025) · Molecular Biology of the Cell · doi:10.1091/mbc.e24-08-0354 · Cited by 5

Computational Analysis of Drug Resistance of Taxanes Bound to Human Β-Tubulin Mutant (D26e)

Uba, A. İ., Bui-Linh, C., Thornton, J. M., Olivieri, M., & Wu, C. F. (2023) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2023.108503 · Cited by 5

Protein Modelling and Molecular Docking Analysis of Fasciola hepatica β-Tubulin’s Interaction Sites, with Triclabendazole, Triclabendazole Sulphoxide and Triclabendazole Sulphone

Olivares-Ferretti, P., Beltrán, J. F., Salazar, L. A., & Fonseca-Salamanca, F. (2023) · Acta Parasitologica · doi:10.1007/s11686-023-00692-z · Cited by 5

Resistance to Microtubule-Targeting Drugs

Giannakakou, P., & Snyder, J. P. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-336-3_15 · Cited by 5

Protein–Protein Interaction Inhibitors

Hardcastle, I. R. (2017) · Topics in medicinal chemistry · doi:10.1007/7355_2017_27 · Cited by 4

Visualization of Tau–Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique

Shin, S., Lim, S., Jeong, H., Kwan, L. T., & Kim, Y. K. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102978 · Cited by 6

Tubulin and Microtubule Structures

Nogales, E., & Downing, K. H. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-336-3_9 · Cited by 5

Cellular Imaging in Drug Discovery: Imaging and Informatics for Complex Cell Biology

Li, Z., Cvijic, M. E., & Zhang, L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.12328-5 · Cited by 5

Protein–Protein Interaction Inhibitors in Cancer

Hardcastle, I. R. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.12392-3 · Cited by 5

Targeting - Cancer — Small Molecules

de Groot, V. (2007) · Springer eBooks · doi:10.1007/978-0-387-49785-3_13 · Cited by 4

Taxol exploits molecular switches within tubulin to stabilize microtubulesPreprint

Vangos, N. E., DeLear, P. R., Thomas, E. C., Verhey, K. J., DeSantis, M. E., Žanić, M., Sept, D., & Cianfrocco, M. A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.17.725690 · Cited by 1

Structural insight into the stabilization of microtubules by taxanes

Prota, A. E., Lucena-Agell, D., Ma, Y., Estevez-Gallego, J., Li, S., Bargsten, K., Josa-Prado, F., Altmann, K.-H., Gaillard, N., Kamimura, S., et al. (2023) · eLife · doi:10.7554/elife.84791 · Cited by 78

Insights into the mechanism of microtubule stabilization by Taxol

Xiao, H., Verdier-Pinard, P., Fernandez-Fuentes, N., Burd, B., Angeletti, R., Fiser, A., Horwitz, S. B., & Orr, G. A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603704103 · Cited by 319

Possible binding site for paclitaxel at microtubule pores

Magnani, M., Maccari, G., Andreu, J. M., Díaz, J. F., & Botta, M. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.06994.x · Cited by 36

Systematic profiling of taxol and its analogues (taxalogues) binding to β‐tubulin and molecular analysis of their effects on microtubule stabilization

Dou, Z., Ding, X., Feng, Y., Lihua, Z., Gu, Y., & Liu, L. (2023) · Journal of the Chinese Chemical Society · doi:10.1002/jccs.202200440 · Cited by 6