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MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

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Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

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SOCS-1 suppresses TNF- -induced apoptosis through the regulation of Jak activation

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STAT proteins in innate immunity during sepsis: lessons from gene knockout mice.

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Differential expression of SOCS1 in macrophages in relapsing‐remitting and chronic EAE and its role in disease severity

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An RNA-binding protein CP-1 is involved in the STAT3-mediated suppression of NF- B transcriptional activity

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Early Growth Response-1 Regulates Lipopolysaccharide-induced Suppressor of Cytokine Signaling-1 Transcription

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Regulation of Toll-like receptor signaling in the innate immunity

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Integrated Nanovaccine with MicroRNA-148a Inhibition Reprograms Tumor-Associated Dendritic Cells by Modulating miR-148a/DNMT1/SOCS1 Axis

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Identification and characterization of suppressor of cytokine signaling 1 (SOCS-1) homologues in teleost fish

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Dominant transplantation tolerance

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Statins induce suppressor of cytokine signaling‐3 in macrophages

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Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures

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Potential Natural Biomolecules Targeting JAK/STAT/SOCS Signaling in the Management of Atopic Dermatitis

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Toll like receptors and acute allograft rejection

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Multiple mechanisms that prevent excessive brain inflammation

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Suppressor of Cytokine Signaling 1 DNA Administration Inhibits Inflammatory and Pathogenic Responses in Autoimmune Myocarditis

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SOCS-3 Regulates Alveolar Bone Loss in Experimental Periodontitis

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SOCS1 is a negative regulator of metabolic reprogramming during sepsis

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The pro‐inflammatory microRNA miR‐155 influences fibrillar β‐Amyloid1‐42 catabolism by microglia

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Negative regulation of cytokine signaling and inflammatory diseases

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SOCS2 Influences LPS Induced Human Monocyte-Derived Dendritic Cell Maturation

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Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases

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Suppressors of Cytokine Signaling-1 and -3 Regulate Osteoclastogenesis in the Presence of Inflammatory Cytokines

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Increased Cytokine Production in Interleukin-18 Receptor α-deficient Cells Is Associated with Dysregulation of Suppressors of Cytokine Signaling

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Bacterial colonization, probiotics, and clinical disease

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Should We Inhibit Type I Interferons in Sepsis?

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Porcine Reproductive and Respiratory Syndrome Virus Enhances Self-Replication via AP-1–Dependent Induction of SOCS1

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SHIP, TGF-β, and Endotoxin Tolerance

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The Chemoattractants, IL-8 and Formyl-Methionyl-Leucyl-Phenylalanine, Regulate Granulocyte Colony-Stimulating Factor Signaling by Inducing Suppressor of Cytokine Signaling-1 Expression

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Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 up-regulation

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SOCS1 protects protein tyrosine phosphatases by thioredoxin upregulation and attenuates Jaks to suppress ROS-mediated apoptosis

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MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production

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Regulation of Interferon Gamma Signaling by Suppressors of Cytokine Signaling and Regulatory T Cells

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IL-1R-Associated Kinase 4 Is Required for Lipopolysaccharide- Induced Activation of APC

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MicroRNA-181b regulates endotoxin tolerance by targeting IL-6 in macrophage RAW264.7 cells

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SIGIRR puts the brakes on Toll-like receptors

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Seasonal and pandemic influenza H1N1 viruses induce differential expression of SOCS-1 and RIG-I genes and cytokine/chemokine production in macrophages

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Human Toll-Like Receptor 4 (hTLR4): Structural and functional dynamics in cancer

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Differential Activation of NF-κB, AP-1, and C/EBP in Endotoxin-Tolerant Rats: Mechanisms for In Vivo Regulation of Glomerular RANTES/CCL5 Expression

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Burkholderia pseudomallei-Induced Expression of Suppressor of Cytokine Signaling 3 and Cytokine-Inducible Src Homology 2-Containing Protein in Mouse Macrophages: a Possible Mechanism for Suppression of the Response to Gamma Interferon Stimulation

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Procyanidin dimer B2-mediated IRAK-M induction negatively regulates TLR4 signaling in macrophages

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Hepatitis C virus (HCV)-induced suppressor of cytokine signaling (SOCS) 3 regulates proinflammatory TNF-α responses

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Hepatocyte growth control by SOCS1 and SOCS3

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Adenoviral Expression of Suppressor of Cytokine Signaling-1 Reduces Adenovirus Vector-Induced Innate Immune Responses

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Genetic Analysis of Innate Immunity

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Increased expression of suppressor of cytokine signaling-1 (SOCS-1): A mechanism for dysregulated T helper-1 responses in HIV-1 disease

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Differential expression and potential role of SOCS1 and SOCS3 in Wallerian degeneration in injured peripheral nerve

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Cytokine-induced STAT1 activation is increased in patients with primary Sjögren's syndrome

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SOCS1: Regulator of T Cells in Autoimmunity and Cancer

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SOCS-1 Protects against Chlamydia pneumoniae -Induced Lethal Inflammation but Hampers Effective Bacterial Clearance

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The analysis of CIS, SOCS1, SOSC2 and SOCS3 transcript levels in peripheral blood mononuclear cells of systemic lupus erythematosus and rheumatoid arthritis patients

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Sepsis-induced SOCS-3 expression is immunologically restricted to phagocytes

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Discovery of the DIGIRR Gene from Teleost Fish: A Novel Toll–IL-1 Receptor Family Member Serving as a Negative Regulator of IL-1 Signaling

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BAFF synthesis by rheumatoid synoviocytes is positively controlled by α5β1 integrin stimulation and is negatively regulated by tumor necrosis factor α and toll‐like receptor ligands

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Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus

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Modulation of TLR signalling by the C‐terminal Src kinase (Csk) in macrophages

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Early and preferential induction of IL-1 receptor-associated kinase-M in THP-1 cells by LPS derived fromPorphyromonas gingivalis

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The role of Toll-like receptors in multiple sclerosis and possible targeting for therapeutic purposes

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Cell-Autonomous Sex Differences in Gene Expression in Chicken Bone Marrow–Derived Macrophages

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Toll Like Receptors in systemic sclerosis: An emerging target

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Role of Toll-Like Receptor–Driven Innate Immunity in Thoracic Organ Transplantation

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ATF-2 regulates lipopolysaccharide-induced transcription in macrophage cells

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MicroRNA-155 promotes pro-inflammatory functions and augments apoptosis of monocytes/macrophages during Vibrio anguillarum infection in ayu, Plecoglossus altivelis

Nie, L., Cai, S.-Y., Sun, J., & Chen, J. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.11.030 · Cited by 35

SOCS and Herpesviruses, With Emphasis on Cytomegalovirus Retinitis

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Pulmonary Suppressor of Cytokine Signaling-1 Induced by IL-13 Regulates Allergic Asthma Phenotype

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The JAK-STAT pathway promotes persistent viral infection by activating apoptosis in insect vectors

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A novel negative regulator for IL-1 receptor and Toll-like receptor 4

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The NF- B, p38 MAPK and STAT1 pathways differentially regulate the dsRNA-mediated innate immune responses of epidermal keratinocytes

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Zinc Finger Protein Gfi1 Controls the Endotoxin-Mediated Toll-Like Receptor Inflammatory Response by Antagonizing NF-κB p65

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Role of TLRs as signaling cascades to combat infectious diseases: a review

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TLR-induced negative regulatory circuits: role of suppressor of cytokine signaling (SOCS) proteins in innate immunity

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Cytokine signaling-1 suppressor is inducible by IL-1beta and inhibits the catabolic effects of IL-1beta in chondrocytes: its implication in the paradoxical joint-protective role of IL-1beta

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α-ketoglutarate attenuates ischemia-reperfusion injury of liver graft in rats

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MicroRNAs: a crossroad that connects obesity to immunity and aging

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MicroRNA-155: a Novel Armamentarium Against Inflammatory Diseases

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Inhibition of the IL-18 Receptor Signaling Pathway Ameliorates Disease in a Murine Model of Rheumatoid Arthritis

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Advances in immunomodulatory strategies for host-directed therapies in combating tuberculosis

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Effect of caffeic acid phenethyl ester on P revotella intermedia lipopolysaccharide‐induced production of proinflammatory mediators in murine macrophages

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Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway

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HSP60 and CpG-DNA-oligonucleotides differentially regulate LPS-tolerance of hepatic Kupffer cells

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LPS Regulates SOCS2 Transcription in a Type I Interferon Dependent Autocrine-Paracrine Loop

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Severe Pancreatitis with Exocrine Destruction and Increased Islet Neogenesis in Mice with Suppressor of Cytokine Signaling-1 Deficiency

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Efferocytosis in dendritic cells: an overlooked immunoregulatory process

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Guiding the “misguided” – functional conditioning of dendritic cells for the DC‐based immunotherapy against tumours

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SOCS-1 Participates in Negative Regulation of LPS Responses

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SOCS1 hypermethylation increases TNF-α induced apoptosis in a human hepatoma cell line

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SOCS, A Master Attenuator

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