Cigarette smoking and major depression

Covey, Lirio S.; Glassman, Alexander H.; Stetner, Fay

doi:10.1300/j069v17n01_04

Cited by 302Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesCardiac Health and Mental Health

Cigarette smoking and major depression

Covey, Lirio S., Glassman, Alexander H., Stetner, Fay·1998·Journal of Addictive Diseases

DOI 10.1300/j069v17n01_04

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Abstract

The authors review recent literature that has demonstrated an association between cigarette smoking behavior and major depression. Persons with major depression are more likely to smoke and to have difficulty when they try to stop. When they manage to succeed in stopping, such persons are at increased risk of experiencing mild to severe states of depression, including full blown major depression. The period of vulnerability to a new depressive episode appears to vary from a few weeks to several months after cessation. This knowledge suggests a relationship between smoking and depression that is complex, pernicious, and potentially life-long. It is recommended that cessation treatments incorporate screening procedures that will identify those patients with a propensity to depression and monitor the emergence of postcessation depression, particularly in those with a history of depression.

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Smoking and mood disorders are highly co-morbid.
“Nicotine consumption through tobacco products is highly co-morbid with mood disorders, including depression, anxiety and irritability”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as Covey et al., 1998
The rate of smoking relapse is greater in patients with depression.
“the rate of smoking relapse is greater in patients with depression (Covey et al., 1998)”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as Covey et al., 1998

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Authors: Covey, L. S., Glassman, A. H., & Stetner, F.
Affiliations: New York State Psychiatric Institute (US)
Columbia University (US)
Venue: Journal of Addictive Diseases
Publisher: Informa UK Limited
Published: 1998-02-24
Volume: 17
Issue: 1
Pages: 35-46
ISSN: 1055-0887 (ISSN-L)
1545-0848
DOI: 10.1300/j069v17n01_04
OpenAlex: W2064509874
Cited by: 302
References: 26
Citations by year: 2026: 1 · 2025: 6 · 2024: 2 · 2023: 5 · 2022: 1 · 2021: 5 · 2020: 8 · 2019: 4 · 2018: 6 · 2017: 7 · 2016: 11 · 2015: 7 · 2014: 13 · 2013: 12 · 2012: 10
FWCI: 7.36
Type: journal article
Language: en
Open access: closed
Locations: Journal of Addictive Diseases (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords: cigarette smoking, major depressive disorder, smoking cessation, relapse, depression screening, comorbidities
MeSH terms: Smoking Prevention, Administration, Cutaneous, Adult, Aged, Depressive Disorder, Female, Humans, Male, Middle Aged, Nicotine, Recurrence, Risk Factors, Severity of Illness Index, Smoking, Comorbidity, Prevalence, Smoking Cessation

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