ORCA: OpeRational ClassificAtion of Drug Interactions
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The panel used the Hansten and Horn operational classification scheme to reassign major drug-drug interactions to lower severity levels, decreasing interruptive alerting.
“The panel uses the operational classification scheme described by Hansten and Horn to reassign major drug-drug interactions to lower severity levels, and thus decrease interruptive alerting [14].”
From Drug interaction alert override rates in the Meaningful Use era: No evidence of progress (2014) · cites this paper as [14]
Cites
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The central nervous system serotonin syndrome
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Disagreement among drug compendia on inclusion and ratings of drug-drug interactions
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The Top 100 Drug Interactions: A Guide to Patient Management
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Hansten and Horn's drug interactions analysis and management
Hansten, P. D., & Horn, J. R. (2003) · Medical Entomology and Zoology · Cited by 49 · see citing works
Self-citationChiu, T., Bullard, M. J., Chen, J.-C., et al. (1997) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(97)70078-7 · Cited by 34 · see citing works
Interactions Between Oral Contraceptives and Antifungals/Antibacterials
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Visual hallucinations after combining fluoxetine and dextromethorphan
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Potentiation of Oral Anticoagulant Effect by L-thyroxine
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Phansalkar, S., van der Sijs, H., Tucker, A. D., Desai, A. A., Bell, D. S., Teich, J. M., Middleton, B., & Bates, D. W. (2013) · Journal of the American Medical Informatics Association · doi:10.1136/amiajnl-2012-001089 · Cited by 239 · see citing works
Drug interaction alert override rates in the Meaningful Use era: No evidence of progress
Bryant, A. D., Fletcher, G. S., & Payne, T. H. (2014) · Applied Clinical Informatics · doi:10.4338/aci-2013-12-ra-0103 · Cited by 172 · see citing works
Customizing clinical decision support to prevent excessive drug–drug interaction alerts
Horn, J. R., Hansten, P. D., Osborn, J. D., Wareham, P., & Somani, S. (2011) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp100465 · Cited by 26 · see citing works
Self-citationHorn, J., & Ueng, S. (2019) · Annals of Pharmacotherapy · doi:10.1177/1060028019863419 · Cited by 26 · see citing works
Self-citationExploring the Utility of Automated Drug Alerts in Home Healthcare
Feldman, P. H., McDonald, M., Rosati, R. J., Murtaugh, C., Kovner, C., Goldberg, J. D., & King, L. (2006) · Journal for Healthcare Quality · doi:10.1111/j.1945-1474.2006.tb00592.x · Cited by 5 · see citing works
- Authors
- Hansten, P. D., Horn, J. R., & Hazlet, T. K.
- Affiliations
- University of Washington (US)
- Corresponding author
- Hansten, Philip D.
- Venue
- Journal of the American Pharmaceutical Association (1996)
- Publisher
- Elsevier BV
- Published
- 2001-03
- Volume
- 41
- Issue
- 2
- Pages
- 161-165
- ISSN
- 1086-5802 (ISSN-L)
- OpenAlex
- W91312702
- Cited by
- 98
- References
- 13
- Citations by year
- 2026: 2 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 1 · 2019: 6 · 2018: 1 · 2017: 5 · 2016: 3 · 2015: 6 · 2014: 4 · 2013: 13 · 2012: 11
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Pharmaceutical Association (1996) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Keywords
- drug interactions, ORCA
- MeSH terms
- Drug Interactions, Drug Therapy, Computer-Assisted, Humans, Medication Errors, Software, Adverse Drug Reaction Reporting Systems, Drug-Related Side Effects and Adverse Reactions
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