Sleep in eating disorders
Abstract
Sleep research on eating disorders has addressed two major questions: (1) the effects of chronic starvation in anorexia nervosa and of rapidly fluctuating eating patterns in bulimia nervosa on the sleep regulating processes and (2) the search for a significant neurobiological relationship between eating disorders and major depression. At present, the latter question appears to be resolved, since most of the available evidences clearly underline the notion that eating disorders (such as anorexia and bulimia nervosa) and affective disorders are two distinct entities. Regarding the effects of starvation on sleep regulation, recent research in healthy humans and in animals demonstrates that such a condition results in a fragmentation of sleep and a reduction of slow wave sleep. Although several peptides are supposed to be involved in these regulatory processes (i.e. CCK, orexin, leptin), their mode of action is still poorly understood. In opposite to these experimentally induced sleep disturbances are the findings that the sleep patterns in eating disorder patients per se do not markedly differ from those in healthy subjects. However, when focusing on the so-called restricting anorexics, who maintain their chronic underweight by strictly dieting, the expected effects of malnutrition on sleep can be ascertained. Furthermore, at least partial weight restoration results in a 'deepening' of nocturnal sleep in the anorexic patients. However, our knowledge about the neurobiological systems (as well as their circadian pattern of activity) that transmit the effects of starvation and of weight restoration on sleep is still limited and should be extended to metabolic signals mediating sleep.
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Poor sleep is associated with eating disorders.
“For example, poor sleep has also been associated with post-traumatic stress [25], eating disorders [26], and psychosis spectrum experiences such as delusions and hallucinations [23,27].”
From Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials (2021) · cites this paper as [26]
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- Authors
- Lauer, C. J., & Krieg, J.-C.
- Affiliations
- Philipps University of Marburg (DE)
- Corresponding author
- Lauer, Christoph J
- Venue
- Sleep Medicine Reviews
- Publisher
- Elsevier BV
- Published
- 2004-04
- Volume
- 8
- Issue
- 2
- Pages
- 109-118
- ISSN
- 1087-0792 (ISSN-L)
- OpenAlex
- W2039145267
- Cited by
- 97
- References
- 59
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 10 · 2023: 4 · 2022: 6 · 2021: 7 · 2020: 6 · 2019: 6 · 2018: 1 · 2017: 1 · 2016: 6 · 2015: 6 · 2014: 4 · 2013: 9 · 2012: 3
- FWCI
- 0.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sleep Medicine Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- sleep, eating disorders, anorexia nervosa, bulimia nervosa, starvation, sleep fragmentation, slow-wave sleep, weight restoration, malnutrition, depression, circadian rhythm, orexin, leptin, cholecystokinin, sleep regulation
- MeSH terms
- Anorexia Nervosa, Bulimia, Cholinergic Fibers, Circadian Rhythm, Major Depressive Disorder, Dreams, Humans, Nutritional Status, Sleep Wake Disorders, Sleep, REM, Weight Gain
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