Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials
Open accessPublished version of a preprint
Abstract
The extent to which sleep is causally related to mental health is unclear. One way to test the causal link is to evaluate the extent to which interventions that improve sleep quality also improve mental health. We conducted a meta-analysis of randomised controlled trials that reported the effects of an intervention that improved sleep on composite mental health, as well as on seven specific mental health difficulties. 65 trials comprising 72 interventions and N = 8608 participants were included. Improving sleep led to a significant medium-sized effect on composite mental health (g+ = -0.53), depression (g+ = -0.63), anxiety (g+ = -0.51), and rumination (g+ = -0.49), as well as significant small-to-medium sized effects on stress (g+ = -0.42), and finally small significant effects on positive psychosis symptoms (g+ = -0.26). We also found a dose response relationship, in that greater improvements in sleep quality led to greater improvements in mental health. Our findings suggest that sleep is causally related to the experience of mental health difficulties. Future research might consider how interventions that improve sleep could be incorporated into mental health services, as well as the mechanisms of action that explain how sleep exerts an effect on mental health.
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Written from the paper’s full text.
TL;DR
This meta-analysis of randomised controlled trials found that interventions which successfully improved sleep quality produced significant improvements in subsequent mental health, with a medium-sized effect on composite mental health. The findings support a causal role for sleep in mental health difficulties and suggest sleep as a transdiagnostic treatment target.
Key findings
- Across 65 trials, 72 interventions, and N = 8608 participants, improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53, 95% CI −0.68 to −0.38), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), plus smaller effects on stress (g+ = −0.42) and positive psychosis symptoms (g+ = −0.26).
- A dose–response relationship was found: greater improvements in sleep quality were associated with greater improvements in mental health (B = 0.77, 95% CI 0.52 to 1.02, p < 0.001).
- Studies with a significant effect on sleep quality showed larger mental health effects (g = −0.53) than those without (g = −0.12; Q = 17.59, p < 0.001); effects were larger at shorter follow-up (<6 months, g+ = −0.60) than longer follow-up (≥6 months, g+ = −0.18; Q = 10.75, p < 0.01), and larger for clinician-delivered (g+ = −0.63) than self-administered interventions (g+ = −0.34; Q = 4.50, p < 0.05).
- Publication bias was indicated by funnel plot asymmetry (Egger’s regression = −1.09, p < 0.05); trim-and-fill adjustment reduced the composite effect to g+ = −0.35, and Orwin’s fail-safe n was 4101.
Methods
- Systematic review and meta-analysis of RCTs that tested an intervention designed to improve sleep, produced a statistically significant improvement in sleep quality versus control, and measured mental health at a later follow-up; studies were excluded if the intervention specifically targeted mental health or recruited participants under 18 years.
- Searches covered MEDLINE, Embase, PsycINFO, and The Cochrane Library, plus reference lists and trial registries, originally in May 2019 and updated in February 2021; PRISMA selection yielded 65 studies and 72 comparisons.
- Random-effects meta-analysis in R used Hedges g, I² for heterogeneity, moderation/subgroup analyses and meta-regression, Cochrane risk-of-bias assessment, and publication-bias checks including funnel plot, Egger’s test, trim-and-fill, and Orwin’s fail-safe n.
Limitations
- The paper states that relatively few studies examined long-term effects, and longer follow-ups generally showed smaller effects, likely due to diminishing intervention effects on sleep quality over time.
- The paper states that few primary studies existed for outcomes other than depression and anxiety, limiting inferences for other mental health difficulties, and that most analyses were based on CBT for insomnia; the focus on sleep quality may also have excluded studies of sleep disorders with different improvement definitions.
- Evident from the text: most included studies were at high (29, 45%) or unclear (26, 40%) risk of bias, with only 10 (15%) at low risk; main analyses showed substantial heterogeneity (I² = 76–82% for composite, depression, and anxiety), and publication bias was present, with trim-and-fill reducing the composite effect.
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Claims the paper makes
0 of 36 cited sources checked · 0 supported · 0 flagged
- Findingown data
Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53).
“Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), as well as significant small-to-medium sized effects on stress (g+ = −0.42), and finally small significant effects on positive psychosis symptoms (g+ = −0.26).”
Quote in the paperSubstantial claim - Findingown data
The meta-analysis included 65 trials comprising 72 interventions and N = 8608 participants.
“65 trials comprising 72 interventions and N = 8608 participants were included.”
- Also stated in: § Study characteristics · plain
“The 65 studies provided 72 comparisons between an intervention that successfully improved sleep quality vs. a control group.”
- Also stated in: § Study characteristics · plain
“A total of N = 8608 participants took part across the 72 interventions.”
Quote in the paperNot a substantial claim - Also stated in: § Study characteristics · plain
- Findingown data
After eleven outlying effect sizes were removed, the composite mental health effect was relatively homogeneous (I2 = 20%, Q = 75.24, p = 0.0888).
“and now relatively homogeneous (I2 = 20%, Q = 75.24, p = 0.0888).”
Quote in the paperNot a substantial claim - Findingown data
Improving sleep led to a significant medium-sized effect on depression (g+ = −0.63).
“Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), as well as significant small-to-medium sized effects on stress (g+ = −0.42), and finally small significant effects on positive psychosis symptoms (g+ = −0.26).”
Quote in the paperSubstantial claim - Findingown data
Improving sleep led to a significant medium-sized effect on rumination (g+ = −0.49).
“Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), as well as significant small-to-medium sized effects on stress (g+ = −0.42), and finally small significant effects on positive psychosis symptoms (g+ = −0.26).”
Quote in the paperSubstantial claim
- Findingown data
The interventions had a large and statistically significant effect on sleep quality at the earliest follow-up point reported (g+ = −1.07, 95% CI = −1.26 to −0.88, p < 0.001).
“The interventions had large and statistically significant effects on sleep quality at the earliest follow-up point reported (g+ = −1.07, 95% CI = −1.26 to −0.88, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
After twelve outlying effect sizes were removed, heterogeneity for the sleep quality effect was reduced to moderate levels (I2 = 43%, Q = 102.32, p < 0.001).
“and heterogeneity was reduced to moderate levels (I2 = 43%, Q = 102.32, p < 0.001).”
Quote in the paperNot a substantial claim - Findingown data
Improving sleep led to a significant small-to-medium sized effect on stress (g+ = −0.42).
“Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), as well as significant small-to-medium sized effects on stress (g+ = −0.42), and finally small significant effects on positive psychosis symptoms (g+ = −0.26).”
Quote in the paperSubstantial claim - Findingown data
There was substantial heterogeneity between the effect sizes for composite mental health outcomes (I2 = 76%, Q = 291.94, p < 0.001).
“however, there was substantial heterogeneity between the effect sizes, (I2 = 76%, Q = 291.94, p < 0.001).”
Quote in the paperNot a substantial claim - Findingown data
Improving sleep led to a significant small effect on positive psychosis symptoms (g+ = −0.26).
“Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), as well as significant small-to-medium sized effects on stress (g+ = −0.42), and finally small significant effects on positive psychosis symptoms (g+ = −0.26).”
Quote in the paperSubstantial claim - Findingown data
Improving sleep led to a significant medium-sized effect on anxiety (g+ = −0.51).
“Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), as well as significant small-to-medium sized effects on stress (g+ = −0.42), and finally small significant effects on positive psychosis symptoms (g+ = −0.26).”
Quote in the paperSubstantial claim - Findingown data
Heterogeneity between studies for the effect of interventions on sleep quality was substantial (I2 = 79%, Q = 331.93, p < 0.001).
“although heterogeneity between studies was substantial (I2 = 79%, Q = 331.93, p < 0.001).”
Quote in the paperNot a substantial claim - Findingown data
The 72 interventions that successfully improved sleep quality had a statistically significant, medium-sized effect on subsequent composite mental health outcomes (g+ = −0.53, 95% CI = −0.68 to −0.38, p < 0.001).
“On average, the 72 interventions that successfully improved sleep quality had a statistically significant, medium-sized effect on subsequent composite mental health outcomes, (g+ = −0.53, 95% CI = −0.68 to −0.38, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
After twelve outlying effect sizes were removed, the effect of the interventions on sleep quality remained large and statistically significant (g+ = −0.97, 95% CI = −1.07 to −0.88, p < 0.001).
“After twelve outlying effect sizes were removed, the effect of the interventions on sleep quality remained large and statistically significant (g+ = −0.97, 95% CI = −1.07 to −0.88, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
Meta-regression revealed a statistically significant dose-response effect for the association between the effect of interventions on sleep quality and the effect on subsequent mental health outcomes (B = 0.77, 95% CI = 0.52 to 1.02, p < 0.001).
“meta-regression revealed a statistically significant dose–response effect for the association between the effect of interventions on sleep quality and the effect on subsequent mental health outcomes (B = 0.77, 95% CI = 0.52 to 1.02, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
Interventions that successfully improved sleep quality had a small, adverse effect on suicidal ideation across two comparisons (g+ = 0.10, 95% CI = −3.74 to 3.94, p = 0.804).
“Interventions that successfully improved sleep quality had a small, adverse effect on suicidal ideation (g+ = 0.10, 95% CI = −3.74 to 3.94, p = 0.804) across two comparisons.”
Quote in the paperNot a substantial claim - Findingown data
Interventions that successfully improved sleep quality had a statistically significant, small-to-medium sized effect on stress across six comparisons (g+ = −0.42, 95% CI = −0.79 to −0.05, p = 0.033).
“Interventions that successfully improved sleep quality had a statistically significant, small-to-medium sized effect on stress (g+ = −0.42, 95% CI = −0.79 to −0.05, p = 0.033), across six comparisons.”
Quote in the paperSubstantial claim - Findingown data
Orwin's failsafe n test suggested that an additional 4101 comparisons producing null effects would be needed to reduce the average effect of improving sleep on composite outcomes to zero.
“Orwin's failsafe n test suggested that an additional 4101 comparisons producing null effects would be needed to reduce the average effect of improving sleep on composite outcomes to zero.”
Quote in the paperSubstantial claim - Findingown data
There were no significant differences in the effect of improved sleep quality on mental health between CBTi interventions including modules addressing processes associated with mental health (g = −0.44, 95% CI = −0.59 to −0.29, p < 0.001) and those that did not (g = −0.48, 95% CI = −0.65 to −0.32, p < 0.001, Q = 2.51, p = 0.285).
“There were no significant differences in the effect of improved sleep quality on mental health between CBTi interventions including modules addressing processes associated with mental health (g = −0.44, 95% CI = −0.59 to −0.29, p < 0.001), relative to those that did not (g = −0.48, 95% CI = −0.65 to −0.32, p < 0.001, Q = 2.51, p = 0.285).”
Quote in the paperSubstantial claim - Findingown data
There was significant variation in the size of the effect of improving sleep on mental health between countries (Q = 53.69, p < 0.001).
“Finally, there was significant variation in the size of the effect between countries (Q = 53.69, p < 0.001).”
Quote in the paperNot a substantial claim - Findingown data
No other statistically significant categorical moderator effects were found.
“No other statistically significant categorical moderator effects were found.”
Quote in the paperNot a substantial claim - Findingown data
There was substantial heterogeneity for the effect of interventions on depression (I2 = 81%, Q = 322.09, p < 0.001).
“however, once again, there was substantial heterogeneity, (I2 = 81%, Q = 322.09, p < 0.001).”
Quote in the paperNot a substantial claim - Findingown data
Interventions delivered face-to-face by a clinician or therapist were associated with significantly larger effects on mental health (g+ = −0.63) than those that were self-administered by participants (g+ = −0.34, Q = 4.50, p < 0.05).
“Furthermore, interventions that were delivered face-to-face by a clinician or therapist were associated with significantly larger effects on mental health, (g+ = −0.63), than those that were self-administered by participants, (g+ = −0.34, Q = 4.50, p < 0.05).”
Quote in the paperNot a substantial claim - Findingown data
A funnel plot of the effect of improving sleep quality on composite outcomes revealed asymmetry in the effect sizes (Egger's regression = −1.09, 95% CI = −1.91 to −0.28, p < 0.05).
“A funnel plot of the effect of improving sleep quality on composite outcomes revealed asymmetry in the effect sizes (Egger's regression = −1.09, 95% CI = −1.91 to −0.28, p < 0.05, see Fig. 8).”
Quote in the paperSubstantial claim - Findingown data
The present research found that improving sleep has a significant beneficial impact on future mental health in those with non-clinical experiences.
“The present research found that improving sleep has a significant beneficial impact on future mental health in those with non-clinical experiences”
Quote in the paperSubstantial claim - Findingown data
After nine outlying effect sizes were removed, heterogeneity for the depression effect was moderate (I2 = 32%, Q = 74.86, p = 0.0164).
“with moderate heterogeneity, (I2 = 32%, Q = 74.86, p = 0.0164).”
Quote in the paperNot a substantial claim - Findingown data
After nine outlying effect sizes were removed, the effect of improving sleep on depression remained medium-sized (g+ = −0.47, 95% CI = −0.57 to −0.37, p < 0.001).
“After re-running the analysis with nine outlying effect sizes removed, the effect of improving sleep on depression remained medium-sized, (g+ = −0.47, 95% CI = −0.57 to −0.37, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
With 65 RCTs and N = 8608 participants, the present review is one of the largest studies of the effect of improving sleep on mental health to date.
“with 65 RCTs and N = 8608 participants, the present review is one of the largest studies of the effect of improving sleep on mental health to date.”
Quote in the paperNot a substantial claim - Findingown data
Interventions that successfully improved sleep quality had a statistically significant, small-to-medium sized effect on anxiety across 35 comparisons (g+ = −0.50, 95% CI = −0.76 to −0.24, p < 0.001).
“Interventions that successfully improved sleep quality had a statistically significant, small-to-medium sized effect on anxiety across 35 comparisons, (g+ = −0.50, 95% CI = −0.76 to −0.24, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
Only one study reported the effect of improving sleep on burnout, finding almost zero effect (g = −0.03, CI = −0.58 to 0.52, p = 0.917).
“Only one study reported the effect of improving sleep on burnout finding almost zero effect (g = −0.03, CI = −0.58 to 0.52, p = 0.917).”
Quote in the paperNot a substantial claim - Findingown data
The effect of improving sleep on mental health was larger in studies with shorter follow-up periods (<6 months, g+ = −0.60) than in studies with longer follow-ups (≥6 months, g+ = −0.18, Q = 10.75, p < 0.01).
“The effect of improving sleep on mental health was larger in studies with shorter follow-up periods, (i.e., <6 months, g+ = −0.60), than in studies with longer follow-ups, (i.e., 6 months, g+ = −0.18, Q = 10.75, p < 0.01).”
Quote in the paperNot a substantial claim - Findingown data
Interventions that successfully improved sleep quality had a medium-to-large effect on PTSD across two comparisons (g+ = −0.72, 95% CI = −2.90 to 1.46, p = 0.149), with zero heterogeneity.
“Interventions that successfully improved sleep quality had a medium-to-large effect on PTSD (g+ = −0.72, 95% CI = −2.90 to 1.46, p = 0.149) across two comparisons, with zero heterogeneity (I2 = 0%, Q = 0.59, p = 0.442).”
Quote in the paperNot a substantial claim - Findingown data
Interventions that successfully improved sleep quality had a small effect on total PANSS symptoms across three comparisons (g+ = −0.17, 95% CI = −0.53 to 0.19, p = 0.18), with zero heterogeneity.
“Interventions that successfully improved sleep quality had a small effect on total symptoms as indicated by the PANSS (g+ = −0.17, 95% CI = −0.53 to 0.19, p = 0.18) across three comparisons, with zero heterogeneity (I2 = 0%, Q = 0.41, p = 0.813).”
Quote in the paperSubstantial claim - Findingown data
After four outlying effect sizes were removed, the effect of improving sleep on anxiety outcomes was small-to-medium sized but still statistically significant (g+ = −0.38, 95% CI = −0.49 to −0.27, p < 0.001).
“After re-running the analysis with four outlying effect sizes removed, the effect improving sleep on anxiety outcomes was small-to-medium sized, but still statistically significant, (g+ = −0.38, 95% CI = −0.49 to −0.27, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
There were substantial levels of heterogeneity for the effect of interventions on anxiety (I2 = 82%, Q = 187.02, p < 0.001).
“with substantial levels of heterogeneity, (I2 = 82%, Q = 187.02, p < 0.001).”
Quote in the paperNot a substantial claim - Findingown data
The methodological quality of the included studies was not associated with the effect of improving sleep on composite mental health outcomes (Q = 0.72, p = 0.395).
“The methodological quality of the included studies was not associated with the effect of improving sleep on composite mental health outcomes, Q = 0.72, p = 0.395.”
Quote in the paperNot a substantial claim - Findingown data
Interventions that successfully improved sleep quality had a statistically significant, medium-sized effect on depression across 61 comparisons (g+ = −0.63, 95% CI = −0.83 to −0.43, p < 0.001).
“Interventions that successfully improved sleep quality had a statistically significant, medium-sized effect on depression across 61 comparisons, (g+ = −0.63, 95% CI = −0.83 to −0.43, p < 0.001)”
Quote in the paperSubstantial claim - Findingown data
Interventions that successfully improved sleep quality had a small effect on negative symptoms across two comparisons (g+ = −0.28, 95% CI = −3.22 to 2.65, p = 0.436), with zero heterogeneity.
“Finally, interventions that successfully improved sleep quality had a small effect on negative symptoms (g+ = −0.28, 95% CI = −3.22 to 2.65, p = 0.436) across k = 2 comparisons, with zero heterogeneity (I2 = 0%, Q = 1, p = 0.318).”
Quote in the paperNot a substantial claim - Findingown data
Interventions that successfully improved sleep quality had a statistically significant, medium sized effect on rumination across four comparisons (g+ = −0.49, 95% CI = −0.93 to −0.04, p = 0.041), with moderate heterogeneity.
“Interventions that successfully improved sleep quality had a statistically significant, medium sized effect on rumination (g+ = −0.49, 95% CI = −0.93 to −0.04, p = 0.041) across four comparisons, with moderate heterogeneity (I2 = 36%, Q = 4.65, p = 0.1991).”
Quote in the paperSubstantial claim - Findingown data
After four outlying effect sizes were removed, heterogeneity for the anxiety effect was lower (I2 = 43%, Q = 52.49, p = 0.0067).
“with lower levels of heterogeneity, (I2 = 43%, Q = 52.49, p = 0.0067).”
Quote in the paperNot a substantial claim - Findingown data
No other continuous variables significantly moderated the effect of improving sleep on mental health.
“No other continuous variables significantly moderated the effect of improving sleep on mental health.”
Quote in the paperNot a substantial claim - Findingown data
Interventions that successfully improved sleep quality had a small effect on positive symptoms across five comparisons (g+ = −0.26, 95% CI = −0.43 to −0.08, p = 0.014), with zero heterogeneity.
“Interventions that successfully improved sleep quality had a small effect on positive symptoms (g+ = −0.26, 95% CI = −0.43 to −0.08, p = 0.014) across five comparisons, with zero heterogeneity (I2 = 0%, Q = 1.71, p = 0.788).”
Quote in the paperSubstantial claim - Findingnone given
Relatively few studies examined the effect of improving sleep over the long term.
“relatively few studies examined the effect of improving sleep over the long term.”
Quote in the paperNot a substantial claim - Premisecitation
People with insomnia at baseline had a two-fold risk of developing depression at follow-up compared with people who did not experience insomnia.
“Furthermore, a meta-analysis of 21 longitudinal studies reported that people with insomnia at baseline had a two-fold risk of developing depression at follow-up compared with people who did not experience insomnia [13].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [13] Baglioni, 2011, Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies, J Affect Disord source
Not checked in the free run.
- Premisecitation
Longitudinal designs are prone to residual confounding and other forms of bias that limit causal inference.
“Longitudinal designs provide stronger evidence, but are prone to residual confounding [[36], [37], [38]] and other forms of bias that limit causal inference [[39], [40], [41], [42], [43]].”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [36] Achen, 2005, Let's put garbage-can regressions and garbage-can probits where they belong, Conflict Manag Peace Sci source
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- cites [37] Spector, 2011, Methodological urban legends: the misuse of statistical control variables, Organ Res Methods source
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- cites [38] Zapf, 1996, Longitudinal studies in organizational stress research: a review of the literature with reference to methodological issues, J Occup Health Psychol source
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- Premisereasoning
The effect of improving sleep on other mental health outcomes, using different approaches to intervention, is limited.
“Therefore, the effect of improving sleep on other mental health outcomes, using different approaches to intervention, is limited.”
Quote in the paperSubstantial claim - Premisenone given
Previous reviews have included studies that did not successfully manipulate sleep.
“First, previous reviews have included studies that did not successfully manipulate sleep (i.e., the intervention did not improve sleep relative to controls).”
Quote in the paperSubstantial claim - Premisecitation
Cross-sectional designs cannot say whether one variable precedes the other in a causal chain.
“For example, cross-sectional designs tell us that variables are associated in some way, but they cannot say whether one variable precedes the other in a causal chain [35].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [35] Brewer, 2000, Research design and issues of validity, Handb Res Methods Soc Pers Psychol
Not checked in the free run.
- Premisecitation
People with insomnia are 17 times more likely than those without insomnia to experience clinically significant levels of anxiety.
“For example, people with insomnia are 10 and 17 times more likely than those without insomnia to experience clinically significant levels of depression and anxiety, respectively [24].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [24] Taylor, 2005, Epidemiology of insomnia, depression, and anxiety, Sleep source
Not checked in the free run.
- Premisecitation
The best evidence is provided by studies that randomly allocate participants to experimental and control conditions to minimise the effects of potential confounds.
“The best evidence is provided by studies that randomly allocate participants to experimental and control conditions to minimise the effects of potential confounds [44,45].”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [44] Woodward, 2005
Not checked in the free run.
- cites [45] Cartwright, 2007
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- Premisenone given
Most research on the association between sleep and mental health is observational in design.
“Unfortunately, most research on the association between sleep and mental health is observational in design.”
Quote in the paperSubstantial claim - Interpretationown data
The primary studies included in the present review successfully manipulated sleep quality, even after accounting for outliers.
“These findings suggest that the primary studies included in the present review successfully manipulated sleep quality, even after accounting for outliers.”
Quote in the paperSubstantial claim - Premisecitation
Poor sleep is associated with psychosis spectrum experiences such as delusions and hallucinations.
“For example, poor sleep has also been associated with post-traumatic stress [25], eating disorders [26], and psychosis spectrum experiences such as delusions and hallucinations [23,27].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [23] Reeve, 2015, The role of sleep dysfunction in the occurrence of delusions and hallucinations: a systematic review, Clin Psychol Rev source
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- cites [27] Scott, 2017, A structural equation model of the relationship between insomnia, negative affect, and paranoid thinking, PLoS One source
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- Premisereasoning
Previous meta-analyses do not permit robust conclusions as to the causal impact of sleep on mental health outcomes.
“However, even these meta-analyses do not permit robust conclusions as to the causal impact of sleep on mental health outcomes for several reasons.”
Quote in the paperSubstantial claim - Premisenone given
Previous reviews have tended to examine the effect of interventions targeting sleep on mental health at the first post-intervention time point.
“Second, reviews have tended to examine the effect of interventions targeting sleep on mental health at the first post-intervention time point.”
Quote in the paperSubstantial claim - Premisecitation
To establish whether sleeping problems are causally associated with mental health difficulties, it is necessary to experimentally manipulate sleep to see whether changes in sleep lead to changes in mental health over time.
“Therefore, to establish whether sleeping problems are causally associated with mental health difficulties, it is necessary to experimentally manipulate sleep to see whether changes in sleep lead to changes in mental health over time (i.e., the interventionist approach to causation, [46]).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [46] Campbell, 2007, An interventionist approach to causation in psychology, Causal Learn Psychol Philos Comput source
Not checked in the free run.
- Interpretationown data
Sleep is causally related to the experience of mental health difficulties.
“Our findings suggest that sleep is causally related to the experience of mental health difficulties.”
Quote in the paperSubstantial claim- Rests on an assumption: The interventions that successfully improved sleep quality did not improve mental health through mechanisms other than improved sleep.
- Premisecitation
Problems sleeping and mental health difficulties are intrinsically linked.
“However, problems sleeping and mental health difficulties are also intrinsically linked [8,9].”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [8] Ford, 1989, Epidemiologic study of sleep disturbances and psychiatric disorders: an opportunity for prevention?, JAMA source
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- cites [9] Baglioni, 2016, Sleep and mental disorders: a meta-analysis of polysomnographic research, Psychol Bull source
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- Premisecitation
It is not possible to conclude whether sleep is causally linked to mental health if the experimental manipulation of sleep is unsuccessful.
“It is not possible to conclude whether sleep is causally linked to mental health if the experimental manipulation of sleep is unsuccessful [51].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [51] Fedak, 2015, Applying the Bradford Hill criteria in the 21st century: how data integration has changed causal inference in molecular epidemiology, Emerg Themes Epidemiol
Not checked in the free run.
- Premisecitation
People with insomnia are 10 times more likely than those without insomnia to experience clinically significant levels of depression.
“For example, people with insomnia are 10 and 17 times more likely than those without insomnia to experience clinically significant levels of depression and anxiety, respectively [24].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [24] Taylor, 2005, Epidemiology of insomnia, depression, and anxiety, Sleep source
Not checked in the free run.
- Premisecitation
Cost savings following sleep intervention have been specifically reported in people with comorbid mental health difficulties such as depression.
“cost savings following sleep intervention have also been specifically reported in people with comorbid mental health difficulties such as depression [86].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [86] Watanabe, 2014, Cost-effectiveness of brief behavioral therapy for insomnia comorbid with depression: analysis of a randomized controlled trial, Psychosom Med
Not checked in the free run.
- Interpretationown data
The effect of improving sleep on composite mental health is robust to possible publication bias.
“Taken together these results suggest that the effect of improving sleep on composite mental health is robust to possible publication bias.”
Quote in the paperSubstantial claim - Interpretationreasoning
Delivering interventions that improve sleep early might limit the risk of developing or exacerbating substantive mental health difficulties.
“raising the possibility that delivering interventions that improve sleep early might limit the risk of developing (or exacerbating) substantive mental health difficulties.”
Quote in the paperSubstantial claim - Interpretationown data
A dearth of primary studies of other mental health difficulties (e.g., psychosis spectrum experiences, suicidal ideation, PTSD, rumination, and burnout) means that it is premature to draw definitive conclusions in these areas.
“A dearth of primary studies of other mental health difficulties (e.g., psychosis spectrum experiences, suicidal ideation, PTSD, rumination, and burnout) mean that it is premature to draw definitive conclusions in these areas.”
Quote in the paperSubstantial claim - Interpretationown data
It is the beneficial effect of improved sleep quality that confers improvements in mental health rather than the inclusion of modules that target processes associated with mental health commonly seen in CBTi protocols.
“This finding suggests that it is the beneficial effect of improved sleep quality that confers improvements in mental health rather than the inclusion of modules that target processes associated with mental health commonly seen in CBTi protocols.”
Quote in the paperSubstantial claim - Interpretationown data
The present findings support the idea that targeting sleep promotes mental health across a range of populations and experiences.
“The present findings support the idea that targeting sleep promotes mental health across a range of populations and experiences.”
Quote in the paperSubstantial claim - Premisecitation
Less severe mild-to-moderate presentations of mental health difficulties can develop over time into more severe mental health diagnoses.
“less severe mild-to-moderate presentations of mental health difficulties can develop over time into more severe mental health diagnoses [88,89]”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [88] Van Os, 2009, A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness–persistence–impairment model of psychotic disorder, Psychol Med source
Not checked in the free run.
- cites [89] Keyes, 2002, The mental health continuum: from languishing to flourishing in life, J Health Soc Behav source
Not checked in the free run.
- Interpretationown data
The smaller effect of improving sleep on mental health at longer follow-ups might be driven by a smaller effect of the interventions on sleep quality at longer follow-ups.
“This suggests that the smaller effect of improving sleep on mental health at longer follow-ups might be driven by a smaller effect of the interventions on sleep quality at longer follow-ups.”
Quote in the paperNot a substantial claim - Interpretationown data
The finding that studies with significant sleep-quality effects had larger mental-health effects strengthens the notion that improvements in sleep are behind improvements in mental health.
“This finding strengthens the notion that improvements in sleep are behind improvements in mental health.”
Quote in the paperSubstantial claim - Premisecitation
Shorter and more variable sleep has been shown to be longitudinally associated with more severe hallucinations and delusional ideation in those at high-risk of psychosis.
“shorter and more variable sleep has been shown to be longitudinally associated with more severe hallucinations and delusional ideation in those at high-risk of psychosis [87].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [87] Reeve, 2019, Sleep duration and psychotic experiences in patients at risk of psychosis: a secondary analysis of the EDIE-2 trial, Schizophr Res source
Not checked in the free run.
- Interpretationown data
Greater improvements in sleep led to greater improvements in mental health.
“suggesting that greater improvements in sleep led to greater improvements in mental health.”
Quote in the paperSubstantial claim - Premisecitation
Offering a digital CBTi intervention (Sleepio) to primary care patients was associated with an average saving of £70.44 per intervention user.
“offering a digital CBTi intervention (Sleepio) to primary care patients was associated with an average saving of £70.44 per intervention user [85]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [85] Sampson, 2021, Digital cognitive behavioural therapy for insomnia and primary care costs in England: an interrupted time series analysis, medRxiv
Not checked in the free run.
- Premisecitation
Improving sleep has been shown to improve aspects of physical health, including fatigue, chronic pain, and overall health related quality of life.
“Improving sleep has also been shown to improve aspects of physical health, including fatigue [81], chronic pain [82,83], and overall health related quality of life [84]”
Quote in the paperNot a substantial claim0 of 4 sources checked- cites [81] Espie, 2008, Randomized controlled clinical effectiveness trial of cognitive behavior therapy compared with treatment as usual for persistent insomnia in patients with cancer, J Clin Oncol source
Not checked in the free run.
- cites [82] Selvanathan, 2021, Cognitive behavioral therapy for insomnia in patients with chronic pain-A systematic review and meta-analysis of randomized controlled trials, Sleep Med Rev source
Not checked in the free run.
- cites [83] Vitiello, 2009, Cognitive behavioral therapy for insomnia improves sleep and decreases pain in older adults with co-morbid insomnia and osteoarthritis, J Clin Sleep Med source
Not checked in the free run.
- cites [84] Kyle, 2010, Insomnia and health-related quality of life, Sleep Med Rev source
Not checked in the free run.
- Interpretationown data
Improving sleep could prove helpful across a range of mental health severities, broadening the possible impact of sleep interventions within healthcare services.
“This suggests that improving sleep could prove helpful across a range of mental health severities, thus broadening the possible impact of sleep interventions within healthcare services.”
Quote in the paperSubstantial claim - Interpretationown data
There were few primary studies for some outcomes, so inferences for mental health outcomes other than depression and anxiety are more limited.
“there were few primary studies for some of the outcomes included in this review. Consequently, in lieu of more studies reporting these outcomes, the inferences that we can make for mental health outcomes other than depression and anxiety are more limited.”
Quote in the paperSubstantial claim
- May combine two claims. 18
- Classified as probably not a substantial claim. 20
May combine two claims.
Findingown dataGreater improvements in sleep quality led to greater improvements in mental health, indicating a dose-response relationship.
“We also found a dose response relationship, in that greater improvements in sleep quality led to greater improvements in mental health.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataAfter eleven outlying effect sizes were removed, the effect of improving sleep on composite mental health outcomes was small-to-medium sized but still statistically significant (g+ = −0.42, 95% CI = −0.49 to −0.34, p < 0.001).
“After re-running the analysis with eleven outlying effect sizes removed, the effect of improving sleep on composite mental health outcomes was small-to-medium sized but still statistically significant, (g+ = −0.42, 95% CI = −0.49 to −0.34, p < 0.001)”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataStudies that found significant effects of the intervention on sleep quality reported larger effects on subsequent composite mental health (g = −0.53, 95% CI = −0.68 to −0.38, p < 0.001) than studies that did not find a significant effect on sleep quality (g = −0.12, 95% CI = −0.24 to 0.01, p = 0.0522), a difference that was statistically significant (Q = 17.59, p < 0.001).
“Studies that found significant effects of the intervention on sleep quality reported larger effects on subsequent composite mental health, (g = −0.53, 95% CI = −0.68 to −0.38, p < 0.001), than studies that did not find a significant effect of the intervention on sleep quality, (g = −0.12, 95% CI = −0.24 to 0.01, p = 0.0522)”
- Also stated in: § Moderators of the effect of improving sleep quality on composite mental health outcomes · plain
“a difference that was statistically significant, (Q = 17.59, p < 0.001).”
Quote in the paperSubstantial claim- Also stated in: § Moderators of the effect of improving sleep quality on composite mental health outcomes · plain
May combine two claims.
Findingown dataThere was no difference in the effect of improving sleep quality on mental health between those with clinically defined mental health difficulties and those with non-clinical experiences, or between those recruited from clinical versus community settings, with both groups receiving significant benefits of improved sleep on mental health.
“we found no difference in the effect of improving sleep quality on mental health between those with clinically defined mental health difficulties and those with non-clinical experiences or between those recruited from clinical vs. community settings, with both groups receiving significant benefits of improved sleep on mental health.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataStudies reporting the effect of the intervention at shorter follow-ups reported larger improvements in sleep quality (g = −1.03, 95% CI = −1.27 to −0.78, p < 0.001) than those reporting longer follow-ups (g = −0.44, 95% CI = −0.62 to −0.27, p < 0.001), a difference that was statistically significant (Q = 14.38, p < 0.001).
“Studies reporting the effect of the intervention at shorter follow-ups reported larger improvements in sleep quality, (g = −1.03, 95% CI = −1.27 to −0.78, p < 0.001), than those reporting longer follow-ups (g = −0.44, 95% CI = −0.62 to −0.27, p < 0.001), a difference that was statistically significant, (Q = 14.38, p < 0.001).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe stress effect had moderate levels of heterogeneity (I2 = 55%, Q = 11.05, p = 0.05) and no outlying effect sizes.
“There were moderate levels of heterogeneity (I2 = 55%, Q = 11.05, p = 0.05), but there were no outlying effect sizes.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataDuval and Tweedie's trim and fill procedure imputed ten studies, resulting in a statistically significant, small-to-medium sized adjusted effect of improving sleep on composite mental health outcomes (g+ = −0.35, 95% CI = −0.55 to −0.16, p < 0.001).
“Ten studies were imputed resulting in a statistically significant, small-to-medium sized adjusted effect of improving sleep on composite mental health outcomes (g+ = −0.35, 95% CI = −0.55 to −0.16, p < 0.001).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe effect of improving sleep quality on composite mental health was medium-sized and statistically significant, regardless of the presence of physical and/or mental health comorbidities.
“The effect of improving sleep quality on composite mental health was medium-sized and statistically significant, regardless of the presence of physical and/or mental health comorbidities.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe suicidal ideation effect had low levels of heterogeneity (I2 = 20%, Q = 1.25, p = 0.263) and no outlying effect sizes.
“There were low levels of heterogeneity (I2 = 20%, Q = 1.25, p = 0.263) and no outlying effect sizes.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataTen studies (15%) were judged as having low risk of bias, 29 studies (45%) as high risk of bias, and 26 studies (40%) as unclear.
“Ten studies (15%) were judged as having low risk of bias, 29 studies (45%) were judged as high risk of bias, and 26 studies (40%) were judged as unclear.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningMost of the analyses are based on CBT interventions for insomnia.
“most of the analyses are based on CBT interventions for insomnia.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisereasoningTo date there has been no or limited attempts to investigate variables that influence or moderate the impact of interventions that improve sleep on mental health.
“Finally, to date there has been no or limited attempts to investigate variables that influence – or moderate – the impact of interventions that improve sleep on mental health.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationPoor sleep contributes to the onset, recurrence, and maintenance of mental health difficulties.
“such that poor sleep contributes to the onset, recurrence, and maintenance of mental health difficulties [[13]∗, [14], [15]∗, [16], [17]].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [[13]∗, [14], [15]∗, [16], [17]]
Not checked in the free run.
May combine two claims.
Premisenone givenEffects at the first post-intervention time point are limited to the short-term where they are likely to be strongest.
“2) effects are limited to the short-term where they are likely to be strongest.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Premisenone givenAt the first post-intervention time point, there is no temporal lag between the measurement of sleep and measurement of mental health.
“1) there is no temporal lag between the measurement of sleep and measurement of mental health (a key tenet of causal inference);”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationPoor sleep is associated with post-traumatic stress.
“For example, poor sleep has also been associated with post-traumatic stress [25], eating disorders [26], and psychosis spectrum experiences such as delusions and hallucinations [23,27].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [25] Harvey, 2003, Sleep and posttraumatic stress disorder: a review, Clin Psychol Rev source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe association between sleep and mental health is well documented.
“The association between sleep and mental health is well documented [9,13,[18], [19], [20], [21], [22], [23]∗].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [9,13,[18], [19], [20], [21], [22], [23]∗]
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationRisk of bias was assessed using the risk of bias assessment criteria developed by the Cochrane Collaboration.
“Risk of bias was assessed using the risk of bias assessment criteria developed by the Cochrane Collaboration [60].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [60] Higgins, 2011, Chapter 8: assessing risk of bias in included studies
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationPublication bias was assessed via visual inspection of a funnel plot and Egger's test.
“Publication bias was assessed via visual inspection of a funnel plot and Egger's test [70].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [70] Egger, 1997, Bias in meta-analysis detected by a simple, graphical test, BMJ source
Not checked in the free run.
May combine two claims.
PremisecitationSpecific sleep disorders, such as sleep apnoea, circadian rhythm disruption, restless leg syndrome, excessive daytime sleepiness and narcolepsy, sleepwalking, and nightmares, are all more prevalent in those experiencing mental health difficulties.
“Studies have also found that specific sleep disorders, such as sleep apnoea [28], circadian rhythm disruption [29], restless leg syndrome [30], excessive daytime sleepiness and narcolepsy [31,32], sleepwalking [33], and nightmares [34] are all more prevalent in those experiencing mental health difficulties.”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [28] Sharafkhaneh, 2005, Association of psychiatric disorders and sleep apnea in a large cohort, Sleep source
Not checked in the free run.
- cites [29] Wulff, 2010, Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease, Nat Rev Neurosci source
Not checked in the free run.
- cites [30] Picchietti, 2005, Restless legs syndrome, periodic limb movements in sleep, and depression, Sleep
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationPoor sleep is associated with eating disorders.
“For example, poor sleep has also been associated with post-traumatic stress [25], eating disorders [26], and psychosis spectrum experiences such as delusions and hallucinations [23,27].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] Lauer, 2004, Sleep in eating disorders, Sleep Med Rev source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe review followed PRISMA guidelines when selecting studies.
“We followed PRISMA guidelines [53] when selecting studies.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [53] Moher, 2009, Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement, BMJ source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataRecords were screened by two members of the review team, and a sub-sample of 10% of each reviewer's records were second checked by the other reviewer, with almost perfect agreement between the reviewers.
“Records were screened by two members of the review team, and a sub-sample of 10% of each reviewer's records were second checked by the other reviewer, with almost perfect agreement between the reviewers (kappa = 1.00 and 0.99).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationOrwin's formula was used to determine the fail-safe n.
“Additionally, Orwin's formula [71] was used to determine the fail-safe n.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [71] Orwin, 1983, A fail-safe N for effect size in meta-analysis, J Educ Stat
Not checked in the free run.
May combine two claims.
Premisenone givenThe focus of previous reviews has been limited to depression and anxiety only, and typically limited to CBTi interventions.
“Third, the focus of previous reviews has been limited to depression and anxiety only, and typically limited to CBTi interventions.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataA sensitivity analysis examining the effect of outliers for each outcome was conducted by rerunning the analysis with any outlying effect sizes removed.
“We conducted a sensitivity analysis examining the effect of outliers for each outcome by rerunning the analysis with any outlying effect sizes removed.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenTo the authors' knowledge, the review is the first to adopt this approach in the field of sleep and mental health.
“To our knowledge, the review is the first to adopt this approach in the field of sleep and mental health”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductreasoningThe review was specifically designed to test the causal association between sleep and mental health (i.e., RCTs only, successful sleep improvement required, temporal lag between measures etc.).
“the review was specifically designed to test the causal association between sleep and mental health (i.e., RCTs only, successful sleep improvement required, temporal lag between measures etc.).”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataTaken together, the findings suggest that improving sleep leads to better mental health, providing strong evidence that sleep plays a causal role in the experience of mental health difficulties.
“Taken together, the findings suggest that improving sleep leads to better mental health, therefore providing strong evidence that sleep plays a causal role in the experience of mental health difficulties.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningImproving sleep might be one tool that can be used in combination with others to limit the risk of transition to more severe mental health difficulties.
“therefore improving sleep might be one tool that can be used in combination with others to limit the risk of transition.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductown dataThe review provides an analysis of possible moderators of the effect of improving sleep on mental health, identifying several key moderators of the effect.
“we provide an analysis of possible moderators of the effect of improving sleep on mental health, identifying several key moderators of the effect.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Study design and conductown dataThe review provides a comprehensive and up-to-date search of RCTs examining the effect of improving sleep on a variety of subsequent mental health outcomes.
“it provides a comprehensive and up-to-date search of RCTs examining the effect of improving sleep on a variety of subsequent mental health outcomes.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Premisenone givenThe timing of sleep is particularly important in circadian rhythm disorders and daytime sleepiness is a key outcome in sleep apnoea research.
“the timing of sleep is particularly important in circadian rhythm disorders and daytime sleepiness is a key outcome in sleep apnoea research.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningThe focus on sleep quality may have precluded some studies that do not focus on insomnia from inclusion.
“it may be that our focus on sleep quality precluded some studies that do not focus on insomnia from inclusion.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisereasoningDifferent sleep disorders have different conceptualisations of improvement that might not include sleep quality.
“different sleep disorders have different conceptualisations of improvement that might not include sleep quality.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationcitationStudies with longer follow-ups generally found smaller effects (although still statistically significant), most likely due to the diminishing effects of interventions on sleep quality over time.
“Those that did report longer follow-ups generally found smaller effects (although still statistically significant), most likely due to the diminishing effects of interventions on sleep quality over time [91].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [91] van der Zweerde, 2019, Cognitive behavioral therapy for insomnia: a meta-analysis of long-term effects in controlled studies, Sleep Med Rev source
Not checked in the free run.
The paper relies on this without support.
The interventions that successfully improved sleep quality did not improve mental health through mechanisms other than improved sleep.
“To better isolate the effect of improved sleep on mental health, we excluded interventions that included specific elements targeting mental health (e.g., CBT elements for depression).”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Improvements in all lifestyle domains targeted are associated with improvements in the QOL mental component summary measure.
“This is aligned with evidence showing that improvements in all lifestyle domains that we targeted is associated with improvements in the QOL mental component summary measure [5, 6, 70, 81, 82].”
From Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study (2026) · cites this paper as [82]
The Results section, Table 3 (page unavailable), reports improved composite mental health following interventions that improved sleep quality. The paper does not establish this association for all targeted lifestyle domains or for the specific QOL mental component summary measure; its composite mental-health outcome is a different measure. (LLM, conf=0.89)
Experimental — accuracy not yet measuredImprovements in sleep, diet and exercise are linked to improvements in depression symptoms.
“This finding aligns with the strong foundation in the literature that improvements in sleep, diet and exercise are linked to improvements in depression symptoms [82, 99, 100].”
From Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study (2026) · cites this paper as [82]
ACT promotes acceptance and value-consistent action, reducing the struggle that sustains insomnia-related arousal.
“Rather than suppressing distressing cognitions, ACT promotes acceptance and value-consistent action, thereby reducing the struggle that sustains insomnia-related arousal [78].”
From Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice. (2026) · cites this paper as [78]
The Results section reports effects of improving sleep quality on outcomes including rumination, but does not describe acceptance and commitment therapy (ACT). Searches for ACT, acceptance, value-consistent action, and insomnia-related arousal found no passage explaining the mechanism attributed to ACT. (LLM, conf=0.76)
Experimental — accuracy not yet measuredACT extends the principles of mindfulness by emphasizing psychological flexibility, the capacity to tolerate aversive internal experiences without engaging in maladaptive control efforts.
“ACT extends the principles of mindfulness by emphasizing psychological flexibility -one's capacity to tolerate aversive internal experiences, such as anxiety or wakefulness, without engaging in maladaptive control efforts [78].”
From Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice. (2026) · cites this paper as [78]
The Method > Outcomes and prioritization table lists mindfulness as a comparator in sleep-intervention trials, but does not describe ACT or its principles; no page number is available for that passage. Searches for acceptance and commitment therapy, psychological flexibility, and aversive internal experiences found no passage in our copy addressing the claim. (LLM, conf=0.75)
Experimental — accuracy not yet measuredA recent meta-analysis concluded that sleep improvement after different non-pharmacological treatments for insomnia is causally related to improvements in mental health.
“A recent meta-analysis concluded that sleep improvement after different non-pharmacological treatments for insomnia is causally related to improvements in mental health [19].”
From Cognitive behavioral therapy for insomnia in patients with mental disorders and comorbid insomnia: A systematic review and meta-analysis (2022) · cites this paper as [19]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Sleep-restriction intervention count differs
MinorThe intervention summary reports two sleep-restriction-only comparisons, but Table 4 lists one.
“sleep restriction alone (2, 3%)”
“| Intervention type | Sleep restriction onlyc | 1 | – | – | |”
Significant-sleep-effect moderator Q differs
MinorThe moderator comparison is reported as Q = 17.59 in the text but Q = 17.69 in Table 4.
“a difference that was statistically significant, (Q = 17.59, p < 0.001)”
“| Significant effect on sleepa | Yes | 72 | −0.53 | −0.69 to −0.38 | 17.69∗∗∗ |”
Anxiety pooled results differ between Table 3 and the text
MinorTable 3 reports an anxiety effect of −0.51 and Q of 186.92; the anxiety results paragraph reports −0.50 and Q of 187.02.
“| Anxiety | −0.51∗∗∗ | −0.77 to −0.24 | 82% | 186.92∗∗∗ | 35 | 5819 |”
“(g+ = −0.50, 95% CI = −0.76 to −0.24, p < 0.001), with substantial levels of heterogeneity, (I2 = 82%, Q = 187.02, p < 0.001)”
Anxiety comparison count differs between the text and Table 3
MinorThe study characteristics report 33 comparisons measuring anxiety, whereas Table 3 reports 35 anxiety comparisons.
“33 (46%) reported a measure of anxiety”
“| Anxiety | −0.51∗∗∗ | −0.77 to −0.24 | 82% | 186.92∗∗∗ | 35 | 5819 |”
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Flagged first, then by citations
7 of the 194 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
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BackgroundInfluentialO’Connor, R. C., Worthman, C. M., Abanga, M. A., Athanassopoulou, N., Boyce, N., Chan, L. F., Christensen, H. M., Das‐Munshi, J., Downs, J. L., Koenen, K. C., et al. (2023) · The Lancet Psychiatry · doi:10.1016/s2215-0366(23)00058-5 · Cited by 128 · see citing works
“19 Behavioural factors including smoking and substance use, poor sleep, 45 poor diet, 46 and inactivity 16 also pervasively affect mental states and underpin links to physical comorbidities.”
BackgroundNovel strategies for cancer immunotherapy: counter-immunoediting therapy
Liu, S., Sun, Q., & Ren, X. (2023) · Journal of Hematology & Oncology · doi:10.1186/s13045-023-01430-8 · Cited by 98 · see citing works
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Koohsari, M. J., Yasunaga, A., McCormack, G. R., Shibata, A., Ishii, K., Liao, Y., Nagai, Y., & Oka, K. (2023) · Scientific Reports · doi:10.1038/s41598-023-27882-z · Cited by 72 · see citing works
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“Additionally, considering that improving sleep quality is associated with enhanced physical and mental health [47], future research should evaluate healthcare students’ sleep knowledge and provide them with sleep education.”
BackgroundGrelle, K., Shrestha, N., Ximenes, M. C., Perrotte, J. K., Cordaro, M., Deason, R. G., & Howard, K. J. (2023) · Journal of Adult Development · doi:10.1007/s10804-023-09442-x · Cited by 66 · see citing works
“Given the established research on quality sleep and improved mental health, it is important to reframe quality sleep as an integral aspect of supporting mental health, especially at the onset of traumatic stressor events (Scott et al., 2021).”
BackgroundTime to Sleep?—A Review of the Impact of the COVID-19 Pandemic on Sleep and Mental Health
Neculicioiu, V. S., Colosi, I. A., Costache, C. A., Sevastre-Berghian, A., & Clichici, S. V. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063497 · Cited by 62 · see citing works
“The causal relation between altered sleep and decreased mental health is evidenced by the fact that improvements in sleep translate to improvements in mental health such as depression, anxiety, rumination and stress [6].”
BackgroundGroves, C. I., Huong, C., Porter, C. D., Summerville, B., Swafford, I., Witham, B., Hayward, M., KWAN, M. Y. W., & Brown, D. M. Y. (2024) · Journal of Activity Sedentary and Sleep Behaviors · doi:10.1186/s44167-024-00048-6 · Cited by 59 · see citing works
Temporomandibular disorders and mental health: shared etiologies and treatment approaches
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“Furthermore, a meta-analysis encompassing 65 trials and 8,608 participants found that improving sleep positively impacted mental health, irrespective of the severity of mental health difficulties or the presence of comorbid conditions [188].”
Association of sleep duration and risk of mental disorder: a systematic review and meta-analysis
Zhang, J., He, M., Wang, X., Jiang, H., Huang, J., & Liang, S. (2023) · Sleep And Breathing · doi:10.1007/s11325-023-02905-1 · Cited by 63 · see citing works
“A meta-analysis of seven cohort studies by Zhai and colleagues 74 found that long and short sleep durations increase the risk of depression in adults.”
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“Sleep is a fundamental behavior that fills approximately one-third of a human’s lifetime and is critical for both physical and mental well-being [1].”
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“In recent years, there has been growing concern about sleep-related problems (e.g., sleep efficiency, sleep latency or sleep quality) due to the importance of sleep in the overall health of the population, especially in mental health [2].”
BackgroundPsychobiotics and the Microbiota–Gut–Brain Axis: Where Do We Go from Here?
Binda, S., Tremblay, A., Iqbal, U., Kassem, O., Barz, M. L., Thomas, V., Bronner, S., Perrot, T. S., Ismail, N., & Parker, J. A. (2024) · Microorganisms · doi:10.3390/microorganisms12040634 · Cited by 57 · see citing works
“A systematic review by Scott et al. (2021) including 65 studies reported that improving sleep quality leads to better mental health [75] and Staines et al (2022), based on 43 studies, found that improving sleep quality was associated with a reduction of anxiety symptoms [76].”
BackgroundHall, W. L. (2022) · British Journal Of Nutrition · doi:10.1017/s000711452200160x · Cited by 46 · see citing works
“However, there is strong evidence that improving sleep quality can positively impact mental health that is likely to enablehealthier dietary behaviours(42).”
Marquez, J., Francis-Hew, L., & Humphrey, N. (2023) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-023-00687-8 · Cited by 49 · see citing works
Alshammari, B., Alkubati, S. A., Pasay-an, E. A., Alrasheeday, A., Alshammari, H. B., Asiri, S. M., Alshammari, S. B., Sayed, F., Madkhali, N. A. B., Laput, V., et al. (2023) · Healthcare · doi:10.3390/healthcare11182536 · Cited by 48 · see citing works
“As for improving the patient’s sleep quality, it will help to improve mental health [14] and overall clinical outcomes [15].”
BackgroundPoor sleep quality in aging: the association with mental health
Corbo, I., Forte, G., Favieri, F., & Casagrande, M. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20031661 · Cited by 45 · see citing works
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“With evidence for the role of improving sleep leading to improving mental health [26,50], both assessment of sleep and introducing sleep-focused services for students at university may be beneficial to both their sleep and mental health.”
BackgroundThe influence of emotion regulation strategies and sleep quality on depression and anxiety
Sullivan, E. C., James, E., Henderson, L. M., McCall, C., & Cairney, S. A. (2023) · Cortex · doi:10.1016/j.cortex.2023.06.001 · Cited by 47 · see citing works
“…al., 2010; Bi & Chen, 2022; Franceschini et al., 2020; Freeman et al., 2017; French, Mortensen, & Timming, 2022; Randall, Nowakowski, & Ellis, 2019; Scott et al., 2021; Varma, Burge, Meaklim, Junge, & Jackson, 2021) and highlight sleep's role in maintaining affective wellbeing (Bower, Bylsma,…”
BackgroundResultLongitudinal Effects of Elexacaftor/Tezacaftor/Ivacaftor
Graziano, S., Boldrini, F., Pellicano, G. R., Milo, F., Majo, F., Cristiani, L., Montemitro, E., Alghisi, F., Bella, S., Cutrera, R., et al. (2023) · CHEST Journal · doi:10.1016/j.chest.2023.10.043 · Cited by 42 · see citing works
Sleepiness in adults: An umbrella review of a complex construct
Martin, V., Lopez, R., Dauvilliers, Y. A., Rouas, J.-L., Philip, P., & Micoulaud‐Franchi, J. (2022) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2022.101718 · Cited by 41 · see citing works
Depression and Anxiety Are Associated With Cardiovascular Health in Young Adults
Patterson, S., Marcus, M., Goetz, M., Vaccarino, V., & Gooding, H. C. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.122.027610 · Cited by 44 · see citing works
“39 Our study has several limitations.”
Poon, K., Ho, M. S. H., Tai, A. P.-L., Leung, M.-K., Chan, M., & Lau, W. K. (2024) · Scientific Reports · doi:10.1038/s41598-024-56688-w · Cited by 44 · see citing works
Castelo, N., Kushlev, K., Ward, A. F., Esterman, M. S., & Reiner, P. B. (2025) · PNAS Nexus · doi:10.1093/pnasnexus/pgaf017 · Cited by 47 · see citing works
“Finally, we investigated whether people would get more sleep when they did not have access to mobile internet, which could in turn improve psychological functioning (36).”
The Economics of Treatment for Depression
Stecher, C. D., Cloonan, S., & Domino, M. E. (2023) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-061022-040533 · Cited by 42 · see citing works
Harvey, A. G. (2022) · SLEEP · doi:10.1093/sleep/zsac026 · Cited by 38 · see citing works
The past, present, and future of sleep quality assessment and monitoring
Chen, Y., Zhou, E., Wang, Y., Xu, G., Xu, G., & Chen, L. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148333 · Cited by 37 · see citing works
Talkington, G. M., Kolluru, P., Gressett, T. E., Ismael, S., Umar, M., Acquarone, M., Solch-Ottaiano, R. J., White, A., Ouvrier, B., Paré, K., et al. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2024.1465787 · Cited by 38 · see citing works
Gwyther, K., Rice, S., Purcell, R., Pilkington, V., Santesteban‐Echarri, O., Bailey, A. P., & Walton, C. C. (2021) · Psychology of sport and exercise · doi:10.1016/j.psychsport.2021.102094 · Cited by 37 · see citing works
Garel, N., Drury, J., Lévesque, J. T., Goyette, N., Lehmann, A., Looper, K. J., Erritzøe, D., Dames, S., Turecki, G., Rej, S., et al. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1268832 · Cited by 36 · see citing works
“Medical history and treatments Neural, cardiovascular, renal, and hepatic health Conditions commonly associated with depression such as thyroid disorders, anemia, and obstructive sleep apnea To ensure physical safety with ketamine and to address medical conditions that may be contributing to depressive symptoms, parti…”
BackgroundMoussa-Chamari, I., Farooq, A., Romdhani, M., Washif, J. A., Bakare, U., Helmy, M. S., Al-Horani, R., Salamh, P. A., Robin, N., & Hüe, O. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1397924 · Cited by 36 · see citing works
“When such sleep deprivation becomes chronic, it can contribute to mental health issues (12), metabolic disorders that lead to overweight and obesity (13), and/or an increased pain sensitivity (11), thereby impacting physical health perception.”
BackgroundDaily associations between family interaction quality, stress, and objective sleep in adolescents
Bai, S., Buxton, O. M., Master, L., & Hale, L. (2021) · Sleep Health · doi:10.1016/j.sleh.2021.11.006 · Cited by 36 · see citing works
Lin, S., Li, L., Zheng, D., & Jiang, L. (2022) · Behavioral Sciences · doi:10.3390/bs12090316 · Cited by 41 · see citing works
Junge, A., & Hauschild, A. (2023) · Sports Medicine - Open · doi:10.1186/s40798-023-00638-9 · Cited by 37 · see citing works
“A recent review concluded that improving sleep has beneficial effect on depression and anxiety [43].”
BackgroundCai, H., Guo, J., Zhou, J., & Lai, Y. (2023) · PLoS ONE · doi:10.1371/journal.pone.0292887 · Cited by 36 · see citing works
Magnúsdóttir, S., Magnúsdóttir, I., Gunnlaugsdóttir, A. K., Hilmisson, H., Hrólfsdóttir, L., & Eiriksdóttir, A. E. (2024) · Sleep And Breathing · doi:10.1007/s11325-024-03026-z · Cited by 37 · see citing works
“Conversely, sleep curtailments may initiate or exacerbate anxiety and depression symptoms, and sleep improvements may often translate into improvements in anxiety and depression disorders [5].”
Wang, F., Sun, Z., Lin, F., Xu, Y., Wu, E., Sun, X., Zhou, X., & Wu, Y. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.05.043 · Cited by 33 · see citing works
Childhood Lifestyle Behaviors and Mental Health Symptoms in Adolescence
Haapala, E. A., Leppänen, M. H., Kosola, S. K., Appelqvist‐Schmidlechner, K., Kraav, S., Jussila, J. J., Tolmunen, T., Lubans, D. R., Eloranta, A., Schwab, U., et al. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.60012 · Cited by 33 · see citing works
Hickman, R., D’Oliveira, T. C., Davies, A., & Shergill, S. S. (2024) · Sensors · doi:10.3390/s24144701 · Cited by 34 · see citing works
Remskar, M., Western, M. J., & Ainsworth, B. (2024) · British Journal of Health Psychology · doi:10.1111/bjhp.12745 · Cited by 32 · see citing works
“…moderate effect size in a meta-analysis by Jayawardene et al. (2017), alleviate symptoms of depression and anxiety with similar potency (Boettcher et al., 2014; Querstret et al., 2018) and improve sleep—itself strongly associated with mental health outcomes (Jiang et al., 2021; Scott et al., 2021).”
Panjeh, S., Nordahl‐Hansen, A., & Cogo‐Moreira, H. (2023) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.1969 · Cited by 31 · see citing works
Parents of Adolescents Who Experience Suicidal Phenomena—A Scoping Review of Their Experience
Rheinberger, D., Shand, F., McGillivray, L., McCallum, S. M., & Boydell, K. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20136227 · Cited by 31 · see citing works
“Evidence has shown that poor sleep quality is linked to poorer mental health [41], which could compound the impacts of already eroding parent mental wellbeing due to caring for an adolescent in crisis.”
BackgroundBozkurt, A., Demirdöğen, E. Y., & Akıncı, M. A. (2024) · Eurasian Journal of Medicine · doi:10.5152/eurasianjmed.2024.23379 · Cited by 31 · see citing works
Active mobility and mental health: A scoping review towards a healthier world
Scrivano, L., Tessari, A., Marcora, S., & Manners, D. N. (2023) · Cambridge Prisms Global Mental Health · doi:10.1017/gmh.2023.74 · Cited by 31 · see citing works
“First, although sleep patterns are crucial intermediates in the relationship between physical and mental health (Scott et al., 2021), we could only find two studies focusing on sleep quality and active travel.”
BackgroundAhlberg, R., Garcia-Argibay, M., Taylor, M., Lichtenstein, P., D'Onofrio, B. M., Butwicka, A., Hill, C., Cortese, S., Larsson, H., & Du Rietz, E. (2023) · BMJ Mental Health · doi:10.1136/bmjment-2023-300809 · Cited by 29 · see citing works
Liu, Z., Zhang, L., Bai, L., Guo, Z., Gao, J., Lin, Y., Zhou, Y., Lai, J., Tao, J., & Chen, L. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.54307 · Cited by 30 · see citing works
Yang, B.-W., Zou, P., Chen, Q., Sun, L., Ling, X., Yang, H., Zhou, N., Wang, L., Huang, L., Liu, J.-Y., et al. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.1040410 · Cited by 32 · see citing works
Samper-Pardo, M., León-Herrera, S., Oliván‐Blázquez, B., Gascón, S., & Sánchez‐Recio, R. (2023) · PLoS ONE · doi:10.1371/journal.pone.0278728 · Cited by 30 · see citing works
State of the Science: The Transdiagnostic Intervention for Sleep and Circadian Dysfunction
Harvey, A. G., & Sarfan, L. D. (2024) · Behavior Therapy · doi:10.1016/j.beth.2024.02.007 · Cited by 33 · see citing works
Zhang, Q., Yi, J., & Wu, Y. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1469779 · Cited by 30 · see citing works
“Deterioration in sleep quality is closely linked to a range of chronic conditions such as depression, cognitive impairment, and cardiovascular diseases (3–5).”
BackgroundAssociation of depression and sleep quality with frailty: a cross-sectional study in China
Zhang, Y., Yu, G., Bai, W., Wu, S., Geng, X., Zhang, W., Liu, Y., Meng, Y., Gao, J., Li, W., et al. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1361745 · Cited by 30 · see citing works
Tang, W. S. W., Min, N. L. X., Krishnan, M. N., Chin, Y. C., & Ho, C. S. H. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13113081 · Cited by 29 · see citing works
“Better sleep improves mental health [82,83].”
Neurodegenerative disorders, metabolic icebergs, and mitohormesis
Phillips, M. C. L., & Picard, M. A. (2024) · Translational Neurodegeneration · doi:10.1186/s40035-024-00435-8 · Cited by 30 · see citing works
“A recent meta-analysis of 65 randomized controlled trials showed that improved sleep leads to better mental health, including improvements in depression, anxiety, rumination, stress, and psychosis [226].”
MethodTranslational approaches to influence sleep and arousal
Brown, R. E., Spratt, T. J., & Kaplan, G. B. (2022) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2022.05.002 · Cited by 29 · see citing works
Herselman, M. F., Bailey, S., Deo, P., Zhou, X., Gunn, K. M., & Bobrovskaya, L. (2022) · Nutrients · doi:10.3390/nu14224776 · Cited by 27 · see citing works
“Furthermore, a recent meta-analysis has also suggested that sleep is causally related to challenges in mental health with improvements in sleep reducing depression, anxiety and stress [43].”
BackgroundChu, A., Samman, S., Galland, B. C., & Foster, M. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.06.019 · Cited by 28 · see citing works
Richardson, K. E., Petukhova, R., Hughes, S. D., Pitt, J., Yücel, M., & Segrave, R. A. (2024) · BMC Public Health · doi:10.1186/s12889-024-17683-y · Cited by 27 · see citing works
Mao, B., Xie, Z., Liu, M., Gong, Y., Wang, H., Yang, S., Liao, M., Xiao, T., Tang, S., Wang, Y., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.188 · Cited by 27 · see citing works
Nighttime smartphone use, sleep quality, and mental health: investigating a complex relationship
Andersen, T. O., Sejling, C., Jensen, A. K., Drews, H. J., Ritz, B. R., Varga, T. V., & Rod, N. H. (2023) · SLEEP · doi:10.1093/sleep/zsad256 · Cited by 31 · see citing works
Zhu, X., Ren, Y., Tan, S., & Ma, X. (2023) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2023.12.037 · Cited by 26 · see citing works
Sleep disturbance and cognition in the elderly: a narrative review
Ni, Y., Yu, M., & Liu, C. (2024) · Anesthesiology and Perioperative Science · doi:10.1007/s44254-024-00066-2 · Cited by 27 · see citing works
“Moreover, a systematic review suggests that obtaining quality sleep aids maintenance of normal emotional and mental health [5].”
The influence of sexual activity on sleep: A diary study
Oesterling, C., Borg, C., Juhola, E., & Lancel, M. (2023) · Journal of Sleep Research · doi:10.1111/jsr.13814 · Cited by 26 · see citing works
“…risk factor for the development of diverse mental disorders, such as depression, anxiety, and posttraumatic stress disorder (Hertenstein et al., 2019), and may aggravate psychopathology and impede recovery (e.g., Belleville et al., 2011; Gee et al., 2019; Ho et al., 2016; Scott et al., 2021).”
BackgroundWasserman, D. (2024) · World Psychiatry · doi:10.1002/wps.21185 · Cited by 26 · see citing works
Hjetland, G. J., Skogen, J. C., Hysing, M., Gradisar, M., & Sivertsen, B. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1548273 · Cited by 29 · see citing works
Association of sleep with mental health in Chinese high school students: a cross‐sectional study
Xue, B., Xue, Y., Zheng, X., Shi, L., Liang, P., Dong, F., Xiao, S., Zhang, J., Qin, Z., Xu, Y., et al. (2022) · Journal of Sleep Research · doi:10.1111/jsr.13697 · Cited by 25 · see citing works
“The association between sleep and mental health has been explored (Scott et al., 2021).”
BackgroundPredicting new-onset post-stroke depression from real-world data using machine learning algorithm
Chen, Y.-M., Chen, P., Lin, W., Hung, K., Chen, Y. B., Hung, C., Wang, L., Wu, C., Hsu, C., & Kao, H. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1195586 · Cited by 25 · see citing works
The Relationship between Personality Traits and COVID-19 Anxiety: A Mediating Model
Kumar, V. V., & Tankha, G. (2022) · Behavioral Sciences · doi:10.3390/bs12020024 · Cited by 23 · see citing works
“Furthermore, research indicates that sleep quality reduces depression, anxiety, and stress [49].”
BackgroundChen, C., Zhang, M., Wang, Z., Deng, J., Bao, Y., Shi, J., Lu, L., & Shi, L. (2025) · Alzheimer's & Dementia · doi:10.1002/alz.70096 · Cited by 24 · see citing works
Salfi, F., Amicucci, G., Corigliano, D., Viselli, L., D’Atri, A., Tempesta, D., & Ferrara, M. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.06.010 · Cited by 23 · see citing works
“As far as the age effect is concerned, our findings are consistent with some studies (e.g., Seeble et al., 2022), although the current literature presents inconsistencies: some investigations showed a positive association between age and post-COVID symptoms (Sudre et al., 2021; Thompson et al.,…”
Multitask Learning for Mental Health: Depression, Anxiety, Stress (DAS) Using Wearables
Saylam, B., & İncel, Ö. D. (2024) · Diagnostics · doi:10.3390/diagnostics14050501 · Cited by 23 · see citing works
“In [30], researchers found that greater improvements in sleep quality lead to more significant improvements in mental health.”
BackgroundZhao, N., Lund, H. N., & Jespersen, K. V. (2024) · European Psychiatry · doi:10.1192/j.eurpsy.2024.1773 · Cited by 26 · see citing works
“One recent meta-analysis showed that better sleep quality was associated with improvements in composite mental health, depression, anxiety, and rumination [4].”
BackgroundHoushyar, M., Karimi, H., Ghofrani-Jahromi, Z., Nouri, S., & Vaseghi, S. (2024) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000757 · Cited by 25 · see citing works
“Sleep significantly affects mood, emotion regulation, and mental health (Triantafillou et al ., 2019; Scott et al ., 2021).”
BackgroundCole, R. (2024) · Journal of Economic Criminology · doi:10.1016/j.jeconc.2024.100108 · Cited by 22 · see citing works
Sleep quality mediates the association between chronotype and mental health in young Indian adults
Chauhan, S., Pandey, R., Vakani, K., Norbury, R., Ettinger, U., & Kumari, V. (2024) · npj Mental Health Research · doi:10.1038/s44184-024-00076-9 · Cited by 25 · see citing works
“Such self-reported sleep alterations are also common in various mental illnesses, for example major depression or anxiety disorders 24 – 27 .”
BackgroundLi, H., Sang, D., Gong, L., Wang, B., Wang, Y., Jia, X. P., Yu, J., Kong, Z., Liu, H., & Zhang, Y. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1451101 · Cited by 27 · see citing works
Zheng, D., Tan, R.-J., Liu, W. Y., Song, P.-C., & Li, F.-D. (2023) · World Journal of Psychiatry · doi:10.5498/wjp.v13.i10.732 · Cited by 22 · see citing works
Benito, G. V., Goldberg, X., Brachowicz, N., Castaño‐Vinyals, G., Blay, N., Espinosa, A., Davidhi, F., Torres, D., Kogevinas, M., de Cid, R., et al. (2024) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2024.102991 · Cited by 22 · see citing works
The impact of sleep deprivation on the functional connectivity of visual-related brain regions
Weng, X., Wen, K., Guo, J., Zhang, P., Zhang, Y., Cao, Q., Han, Q., & Xu, F. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.11.026 · Cited by 21 · see citing works
Mijnster, T., Boersma, G. J., Meijer, E., & Lancel, M. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12071070 · Cited by 22 · see citing works
Guldner, S., Urrila, A. S., Lemaître, H., Massicotte, J., Vulser, H., Miranda, R., Frère, P., Filippi, I., Penttilä, J., Banaschewski, T., et al. (2022) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2022.101193 · Cited by 22 · see citing works
Săndulescu, V., Ianculescu, M., Valeanu, L., & Alexandru, A. (2024) · Algorithms · doi:10.3390/a17090376 · Cited by 21 · see citing works
Al‐Mamun, F., Mamun, M. A., Hasan, M. E., ALmerab, M. M., & Gozal, D. (2024) · Nature and Science of Sleep · doi:10.2147/nss.s481786 · Cited by 21 · see citing works
“21 Mental health problems are significantly associated with sleep disorders 43 and may even foster the risk of suicide.”
BackgroundTamm, S., Tse, K. Y. K., Hellier, J. M., Saunders, K. E. A., Harmer, C. J., Espie, C. A., Reid, M. J., & Kyle, S. D. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.61502 · Cited by 20 · see citing works
The effects of social media restriction: Meta-analytic evidence from randomized controlled trials
Burnell, K., Meter, D. J., Andrade, F. C., Slocum, A., & George, M. J. (2025) · SSM - Mental Health · doi:10.1016/j.ssmmh.2025.100459 · Cited by 23 · see citing works
Li, Z., Zhong, T., & Meng, X. (2025) · BMC Public Health · doi:10.1186/s12889-025-23709-w · Cited by 20 · see citing works
“A significant dose-response relationship was seen between alterations in sleep quality and subsequent enhancements in mental health, indicating that greater improvements in sleep correlate with more substantial benefits in mental health [74].”
Joshi, S. C. (2022) · Sleep and Biological Rhythms · doi:10.1007/s41105-022-00388-3 · Cited by 20 · see citing works
“Lastly, a causal relationship was established between sleep quality and stress, anxiety, and depression in a study conducted on college students [18].”
BackgroundZheng, W., Chen, Q., Yao, L., Zhuang, J., Huang, J., Hu, Y., Yu, S., Chen, T., Wei, N., Zeng, Y., et al. (2023) · Journal of Medical Internet Research · doi:10.2196/45721 · Cited by 20 · see citing works
“Sleep is the most basic physiological need of human beings, and good sleep quality contributes to better mental health, serving as a foundation for a healthy life and efficient learning for college students [25,26].”
Liu, X., Peng, L., Wang, Z., Zeng, P., Mi, Y., & Xu, H. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1100355 · Cited by 20 · see citing works
“A survey found that sleep quality was an important predictor of an individual’s mental wellbeing (23).”
BackgroundSleep and Chronotype in Adults with Persistent Tic Disorders
Ricketts, E., Montalbano, G., Burgess, H., McMakin, D., Coles, M., Piacentini, J., & Colwell, C. (2022) · Journal of Clinical Psychology · doi:10.1002/jclp.23323 · Cited by 17 · see citing works
McCarthy, B., O’Neill, G. J., & Abu‐Ghannam, N. (2022) · Marine Drugs · doi:10.3390/md20080493 · Cited by 19 · see citing works
“Globally, approximately 17% of the adult population suffers from some form of mental health issue [9].”
BackgroundEconomides, M., Male, R., Bolton, H., & Cavanagh, K. (2023) · SLEEP · doi:10.1093/sleep/zsad053 · Cited by 17 · see citing works
“This is consistent with a recent meta-analysis reporting that interventions that improve sleep quality also result in medium-sized improvements across several mental health outcomes, such as depression, anxiety, stress, and composite measures of mental health [56], as well as with recent evidence that sleep is causall…”
ResultDong, X., Li, D., Miao, Y.-F., Zhang, T., Wu, Y., & Pan, C. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.04.034 · Cited by 19 · see citing works
“Loneliness is a negative emotional experience that occurs due to the gap between the actual and desired social interaction of an individual (Scott et al., 2021).”
Saravanan, K., Downey, L. A., Sawyer, A., Jackson, M. L., Berlowitz, D. J., & Graco, M. (2023) · Journal of Neurotrauma · doi:10.1089/neu.2023.0033 · Cited by 21 · see citing works
“9,49 Clinically significant levels of depression and anxiety have been observed to co-occur with sleep issues and disorders, 50,51 and this relationship is observed to be bidirectional.”
The quality of sleep: evaluation among university students
Angelillo, S., Sansone, V., Paduano, G., Lateano, L., Giuseppe, G. D., & Nobile, C. G. A. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1270426 · Cited by 18 · see citing works
- Authors
- Scott, A. J., Webb, T. L., Martyn-St James, M., Rowse, G., & Weich, S.
- Affiliations
- Keele University (GB)
- University of Sheffield (GB)
- Corresponding author
- Scott, Alexander J.
- Venue
- Sleep Medicine Reviews
- Publisher
- Elsevier BV
- Published
- 2021-12
- Volume
- 60
- Pages
- 101556
- ISSN
- 1087-0792 (ISSN-L)
- PMC
- PMC8651630
- OpenAlex
- W3203364067
- Cited by
- 1,094
- References
- 194
- Citations by year
- 2026: 226 · 2025: 349 · 2024: 275 · 2023: 190 · 2022: 51 · 2021: 3
- FWCI
- 21.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Sleep Medicine Reviews (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
- Keele Research Repository (Keele University) (submittedVersion, cc-by)
- PsyArXiv (OSF Preprints) (submittedVersion, cc-by)
- PsyArXiv (OSF Preprints) (submittedVersion)
- Funders
- Research for Patient Benefit Programme (PB-PG- 0817-20027)
- National Institute for Health Research
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- sleep quality, mental health, sleep interventions, depression, anxiety, rumination, stress, psychotic symptoms, dose-response relationship
- MeSH terms
- Sleep Quality, Anxiety, Humans, Mental Health, Psychotic Disorders, Sleep, Randomized Controlled Trials as Topic
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