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Estimating the effective Young's modulus of soft tissues from indentation tests—nonlinear finite element analysis of effects of friction and large deformation
Abstract
A nonlinear finite element model was developed to investigate the biomechanics of indentation, particularly the influence of friction and large deformation on the calculation of the effective Young's modulus from the cylindrical, flat-ended indentation test of soft tissues. A new kappa table was given for calculation of the effective Young's modulus to account for the effects of layered geometry with consideration of the larger deformation. The results indicate that the effect of friction on the calculation of Young's modulus becomes significant with a large aspect ratio and with a large Poisson's ratio. It is found that the factor kappa increases almost proportionally to the increase of the indentation depth, especially obvious with a larger Poisson's ratio v and a larger aspect ratio a/h.
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Cited by
The soft mechanical signature of glial scars in the central nervous system
Moeendarbary, E., Weber, I. P., Sheridan, G. K., Koser, D. E., Soleman, S., Haenzi, B., Bradbury, E. J., Fawcett, J., & Franze, K. (2017) · Nature Communications · doi:10.1038/ncomms14787 · Cited by 406
Subbaroyan, J., Martin, D. C., & Kipke, D. R. (2005) · Journal of Neural Engineering · doi:10.1088/1741-2560/2/4/006 · Cited by 368
In Vivo Penetration Mechanics and Mechanical Properties of Mouse Brain Tissue at Micrometer Scales
Sharp, A. A., Ortega, A. M., Restrepo, D., Curran-Everett, D., & Gall, K. (2009) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2008.2003261 · Cited by 157
Metadata
- Authors
- Zhang, M., Zheng, Y. P., & Mak, A. F. T.
- Venue
- Medical Engineering & Physics
- Publisher
- IOP Publishing
- Published
- 1997-09-01
- Volume
- 19
- Issue
- 6
- Pages
- 512-517
- ISSN
- 1350-4533 (ISSN-L)
- 1873-4030
- OpenAlex
- W2073761920
- Cited by
- 282
- References
- 0
- FWCI
- 2.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Estimating the effective Young's modulus of soft tissues from indentation tests—nonlinear finite element analysis of effects of friction and large deformation. https://app.cochat.ai/papers/10.1016/s1350-4533(97)00017-9
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- Zhang, M., Zheng, Y. P., & Mak, A. F. T. (1997). Estimating the effective Young's modulus of soft tissues from indentation tests—nonlinear finite element analysis of effects of friction and large deformation. Medical Engineering & Physics. https://doi.org/10.1016/s1350-4533(97)00017-9
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