Domoic acid: a fascinating marine toxin

Mos, Lizzy

doi:10.1016/s1382-6689(00)00065-x

Cited by 129Marine Toxins and Detection MethodsMarine and coastal ecosystemsAquatic Ecosystems and Phytoplankton Dynamics

Domoic acid: a fascinating marine toxin

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Mos, Lizzy·2001·Environmental Toxicology and Pharmacology

DOI 10.1016/s1382-6689(00)00065-x

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Abstract

There are indications that toxic algal blooms are increasing because of pollution of coastal waters and worldwide shipping. This mini-review deals with the marine biotoxin domoic acid, also known as amnesic shellfish poison, and its main producing pennate diatom genus Pseudo-nitzschia (Bacillariophyceae). Besides contamination of seafood, these organisms have also been involved in human and marine wildlife mortality. The article aims to give an overview of all biological and environmental factors that should be considered when trying to evaluate a possible increase in toxic blooms of Pseudo-nitzschia spp. Pseudo-nitzschia blooms characteristically occur in a low light regime, at a time when the temperature is falling and at a wide range of salinities. Laboratory studies have shown that the production of domoic acid, a water-soluble amino acid, is related to silicon, phosphorus, nitrogen and trace metal (mainly iron) availability. Domoic acid has no known function in defence or primary metabolism; a role in excretion of excess photosynthetic energy or as a binding ligand for trace metals is suggested. The variability in domoic acid production by different Pseudo-nitzschia spp., or the presence of toxic and non-toxic strains of the same species, cannot be explained. The conclusion is drawn that an increase in toxic blooms of Pseudo-nitzschia spp. might be possible, especially because of the expected increase in nutrient availability from pollution and desert dust. Global warming may have an influence as well by lengthening the growth period for Pseudo-nitzschia, enlarging their global distribution and increasing the dust load through desertification.

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The diatom Nitzschia pungens produces domoic acid, which causes poisoning of shellfish.
“The diatom Nitzschia pungens produces domoic acid, which causes poisoning of shellfish [213].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [213]

Emerging Marine Diseases--Climate Links and Anthropogenic Factors
Harvell, C. D., Kim, K., Burkholder, J. M., Colwell, R. R., Epstein, P. R., Grimes, D. J., Hofmann, E. E., Lipp, E. K., Osterhaus, A. D. M. E., Overstreet, R. M., et al. (1999) · Science · doi:10.1126/science.285.5433.1505 · Cited by 1,836 · see citing works
Toxic Marine Phytoplankton
Granéli, E., Sundström, B., Edler, L., & Anderson, D. M. (1987) · Cited by 1,545 · see citing works
Iron-limited diatom growth and Si:N uptake ratios in a coastal upwelling regime
Hutchins, D. A., & Bruland, K. W. (1998) · Nature · doi:10.1038/31203 · Cited by 1,050 · see citing works
Atmospheric transport of iron and its deposition in the ocean
Duce, R. A., & Tindale, N. W. (1991) · Limnology and Oceanography · doi:10.4319/lo.1991.36.8.1715 · Cited by 1,049 · see citing works
Biology of Plants
Raven, P. H., Evert, R. F., & Eichhorn, S. E. (1966) · Medical Entomology and Zoology · Cited by 874 · see citing works
Mortality of sea lions along the central California coast linked to a toxic diatom bloom
Scholin, C. A., Gulland, F. M. D., Doucette, G. J., Benson, S. R., Busman, M., Chávez, F. P., Cordaro, J., DeLong, R. L., Vogelaere, A. P. D., Harvey, J. T., et al. (2000) · Nature · doi:10.1038/47481 · Cited by 813 · see citing works
Harmful and Toxic Algal Blooms
Peperzak, L., Snoeijer, G., Dijkema, R., Gieskes, W. W. C., Joordens, J. C. A., Peeters, J. C. H., Schol, C. M., Vrieling, E. G., & Zevenboom, W. (1996) · Cited by 762 · see citing works
Biology of Marine Mammals
Vázquez, M. B. S. (2000) · Journal of Experimental Marine Biology and Ecology · doi:10.1016/s0022-0981(00)00175-1 · Cited by 734 · see citing works
Control of atmospheric export of dust from North Africa by the North Atlantic Oscillation
Moulin, C., Lambert, C. E., Dulac, F., & Dayan, U. (1997) · Nature · doi:10.1038/42679 · Cited by 723 · see citing works
Pennate Diatom Nitzschia pungens as the Primary Source of Domoic Acid, a Toxin in Shellfish from Eastern Prince Edward Island, Canada
Bates, S. S., Bird, C. J., de Freitas, A. S. W., Foxall, R. A., Gilgan, M. W., Hanic, L. A., Johnson, G. R., MCCULLOCH, A. W., Odense, P. H., Pocklington, R., et al. (1989) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/f89-156 · Cited by 635 · see citing works
Identifying Marine Diatoms and Dinoflagellates
(1996) · Elsevier eBooks · doi:10.1016/b978-0-12-693015-3.x5000-1 · Cited by 599 · see citing works
Harmful and toxic algal blooms
Yasumoto, T., Oshima, Y., & Fukuyo, Y. (1996) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 485 · see citing works
Harmful algal blooms and red tide problems on the U.S. west coast
Horner, R. A., Garrison, D., & Plumley, F. G. (1997) · Limnology and Oceanography · doi:10.4319/lo.1997.42.5_part_2.1076 · Cited by 379 · see citing works
An iron limitation mosaic in the California upwelling regime
Hutchins, D. A., DiTullio, G. R., Zhang, Y., & Bruland, K. W. (1998) · Limnology and Oceanography · doi:10.4319/lo.1998.43.6.1037 · Cited by 341 · see citing works
Domoic Acid and Amnesic Shellfish Poisoning - A Review
Todd, E. C. D. (1993) · Journal of Food Protection · doi:10.4315/0362-028x-56.1.69 · Cited by 305 · see citing works
Biology of Marine Mammals
Rommel, S. A., & Reynolds, J. E., III (1999) · Medical Entomology and Zoology · Cited by 239 · see citing works
Detection of domoic acid in northern anchovies and california sea lions associated with an unusual mortality event
Lefebvre, K. A., Powell, C. L., Busman, M., Doucette, G. J., Moeller, P. D. R., Silver, J. B., Miller, P. E., Hughes, M. P., Singaram, S., Silver, M. W., et al. (1999) · Natural Toxins · doi:10.1002/(sici)1522-7189(199905/06)7:3 · Cited by 226 · see citing works
Controls on Domoic Acid Production by the Diatom Nitzschia pungens f. multiseries in Culture: Nutrients and Irradïance
Bates, S. S., de Freitas, A. S. W., Milley, J. E., Pocklington, R., Quilliam, M. A., Smith, J. C., & Worms, J. (1991) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/f91-137 · Cited by 192 · see citing works
Domoic acid binds iron and copper: a possible role for the toxin produced by the marine diatom Pseudo-nitzschia
Rue, E. L., & Bruland, K. W. (2001) · Marine Chemistry · doi:10.1016/s0304-4203(01)00053-6 · Cited by 190 · see citing works
Red Tides
Anderson, D. M. (1994) · Scientific American · doi:10.1038/scientificamerican0894-62 · Cited by 186 · see citing works
Sea bird mortality at Cabo San Lucas, Mexico: Evidence that toxic diatom blooms are spreading
Sierra-Beltrán, A. P., Palafox-Uribe, M., Grajales-Montiel, J., Cruz-Villacorta, A. A., & Ochoa, J. L. (1997) · Toxicon · doi:10.1016/s0041-0101(96)00140-7 · Cited by 179 · see citing works
Identifying marine diatoms and dinoflagellates
Sancetta, C. A. (1997) · Marine Geology · doi:10.1016/s0025-3227(97)81154-1 · Cited by 151 · see citing works
A review ofPseudo-nitzschia, with special reference to the Skagerrak, North Atlantic, and adjacent waters
Hasle, G. R., Lange, C., & Syvertsen, E. E. (1996) · Helgoland Marine Research · doi:10.1007/bf02367149 · Cited by 150 · see citing works
The activation of glutamate receptors by kainic acid and domoic acid
Hampson, D. R., & Manalo, J. L. (1998) · Natural Toxins · doi:10.1002/(sici)1522-7189(199805/08)6:3/4 · Cited by 148 · see citing works
Nitzschia pseudodelicatissima - a source of domoic acid in the Bay of Fundy, eastern Canada
Martin, J., Haya, K., Burridge, L. E., & Wildish, D. J. (1990) · Marine Ecology Progress Series · doi:10.3354/meps067177 · Cited by 146 · see citing works
Domoic acid, the toxic amino acid responsible for amnesic shellfish poisoning, now in Pseudonitzschia seriata (Bacillariophyceae) in Europe
Lundholm, N., Skov, J., Pocklington, R., & Moestrup, Ø. (1994) · Phycologia · doi:10.2216/i0031-8884-33-6-475.1 · Cited by 141 · see citing works
Anthropogenically-derived atmospheric nitrogen deposition, marine eutrophication and harmful algal bloom expansion: Is there a link ?
Paerl, H. W., & Whitall, D. R. (1999) · AMBIO · Cited by 139 · see citing works
SEXUAL REPRODUCTION IN THE PENNATE DIATOMS PSEUDO‐NITZSCHIA MULTISERIES AND P. PSEUDODELICATISSIMA (BACILLARIOPHYCEAE)
Давидович, Н. А., & Bates, S. S. (1998) · Journal of Phycology · doi:10.1046/j.1529-8817.1998.340126.x · Cited by 129 · see citing works
Domoic Acid Neurotoxicity in Cultured Cerebellar Granule Neurons Is Mediated Predominantly by NMDA Receptors that Are Activated as a Consequence of Excitatory Amino Acid Release
Berman, F. W., & Murray, T. F. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69020693.x · Cited by 128 · see citing works
Autecology of the diatom Pseudonitzschia australis, a domoic acid producer, from Monterey Bay, California
Buck, K., Uttal-Cooke, L., Pilskaln, C., Roelke, D. L., Villac, M., Fryxell, G. A., Cifuentes, L., & Chavez, F. (1992) · Marine Ecology Progress Series · doi:10.3354/meps084293 · Cited by 123 · see citing works
Tissue distribution and neurotoxic effects of domoic acid in a prominent vector species, the northern anchovy Engraulis mordax
Lefebvre, K. A., Dovel, S., & Silver, M. W. (2001) · Marine Biology · doi:10.1007/s002270000509 · Cited by 102 · see citing works
DOMOIC ACID PRODUCTION IN NITZSCHIA SP. (BACILLARIOPHYCEAE) ISOLATED FROM A SHRIMP‐CULTURE POND IN DO SON, VIETNAM
Kotaki, Y., Koike, K., Yoshida, M., Thuộc, C. V., Huyền, N. T. M., Hồi, N. C., Fukuyo, Y., & Kodama, M. (2000) · Journal of Phycology · doi:10.1046/j.1529-8817.2000.99209.x · Cited by 101 · see citing works
PSEUDO‐NITZSCHIA PUNGENS AND P. MULTISERIES (BACILLARIOPHYCEAE): NOMENCLATURAL HISTORY, MORPHOLOGY, AND DISTRIBUTION 1
Hasle, G. R. (1995) · Journal of Phycology · doi:10.1111/j.0022-3646.1995.00428.x · Cited by 98 · see citing works
Domoic acid-containing toxic mussels produce neurotoxicity in neuronal cultures through a synergism between excitatory amino acids
Novelli, A., Kispert, J., Fernández‐Sánchez, M. T., Torreblanca, A., & Žitko, V. (1992) · Brain Research · doi:10.1016/0006-8993(92)90535-h · Cited by 87 · see citing works
The effect of salinity on growth and amino acid composition in the marine diatom Nitzschia pungens
Jackson, A. E., Ayer, S. W., & Laycock, M. V. (1992) · Canadian Journal of Botany · doi:10.1139/b92-272 · Cited by 67 · see citing works
Microbial utilization of the neurotoxin domoic acid: blue mussels (Mytilus edulis) and soft shell clams (Mya arenaria) as sources of the microorganisms
Stewart, J. E., Marks, L., Gilgan, M. W., Pfeiffer, E., & Zwicker, B. M. (1998) · Canadian Journal of Microbiology · doi:10.1139/w98-028 · Cited by 57 · see citing works
Effect of light: dark cycles and cell apical length on the sexual reproduction of the pennate diatom Pseudo-nitzschia multiseries (Bacillariophyceae) in culture
Hiltz, M., Bates, S. S., & Kaczmarska, I. (2000) · Phycologia · doi:10.2216/i0031-8884-39-1-59.1 · Cited by 47 · see citing works
Comparison of two domoic acid-producing diatoms: a review
Villac, M. C., Roelke, D. L., Villareal, T. A., & Fryxell, G. A. (1993) · Springer eBooks · doi:10.1007/978-94-017-3622-0_23 · Cited by 44 · see citing works
Comparison of two domoic acid-producing diatoms: a review
Villac, M. C., Roelke, D. L., Villareal, T. A., & Fryxell, G. A. (1993) · Hydrobiologia · doi:10.1007/bf00028020 · Cited by 42 · see citing works
Identification of a domoic acid-producingPseudo-nitzschiaspecies (Bacillariophyceae) in the Dutch Wadden Sea with electron microscopy and molecular probes
Vrieling, E. G., Koeman, R. P. T., Scholin, C. A., Scheerman, P., Peperzak, L., Marten Veenhuis, A., & Gieskes, W. W. C. (1996) · European Journal of Phycology · doi:10.1080/09670269600651561 · Cited by 28 · see citing works
Domoic Acid Levels of Naturally Contaminated Scallops as Affected by Canning
Leira, F., Vieites, J. M., Botana, L. M., & Vyeites, M. R. (1998) · Journal of Food Science · doi:10.1111/j.1365-2621.1998.tb15859.x · Cited by 22 · see citing works
Morphology of the Toxin-Producing Diatom Nitzschia pungens Grunow forma multiseries Hasle
MacPhee, D. J., Hanic, L. A., Friesen, D. L., & Sims, D. (1992) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/f92-034 · Cited by 19 · see citing works
Microbial utilization of the neurotoxin domoic acid: blue mussels (Mytilus edulis) and soft shell clams (Mya arenaria) as sources of the microorganisms
Stewart, J. E., Marks, L., Gilgan, M. W., Pfeiffer, E., & Zwicker, B. M. (1998) · Canadian Journal of Microbiology · doi:10.1139/cjm-44-5-456 · Cited by 17 · see citing works

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Amato, A., Kooistra, W. H. C. F., LEVIALDIGHIRON, J., Mann, D. G., Pröschold, T., & Montresor, M. (2006) · Protist · doi:10.1016/j.protis.2006.10.001 · Cited by 445 · see citing works
Pseudo-nitzschia(Bacillariophyceae) species, domoic acid and amnesic shellfish poisoning: revisiting previous paradigms
Lelong, A., Hégaret, H., Soudant, P., & Bates, S. S. (2012) · Phycologia · doi:10.2216/11-37.1 · Cited by 406 · see citing works
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Dust in the Wind: Long Range Transport of Dust in the Atmosphere and Its Implications for Global Public and Ecosystem Health
Griffin, D. W., Kellogg, C. A., & Shinn, E. A. (2001) · Global Change and Human Health · doi:10.1023/a:1011910224374 · Cited by 189 · see citing works
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Metal–organic framework UiO-66 modified magnetite@silica core–shell magnetic microspheres for magnetic solid-phase extraction of domoic acid from shellfish samples
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Gill, S., Murphy, M., Clausen, J., Richard, D. J. A., Quilliam, M. A., MacKinnon, S. L., LaBlanc, P., Mueller, R., & Pulido, O. M. (2003) · NeuroToxicology · doi:10.1016/s0161-813x(03)00014-7 · Cited by 103 · see citing works
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Southern sea otter (Enhydra lutris nereis) population biology at Big Sur and Monterey, California --Investigating the consequences of resource abundance and anthropogenic stressors for sea otter recovery
Tinker, M. T., Tomoleoni, J. A., Weitzman, B. P., Staedler, M. M., Jessup, D., Murray, M. J., Miller, M. A., Burgess, T. L., Bowen, L., Miles, A. K., et al. (2019) · Antarctica A Keystone in a Changing World · doi:10.3133/ofr20191022 · Cited by 39 · see citing works
UVA enhancement of carbon fixation and resilience to UV inhibition in the genus Pseudo-nitzschia may provide a competitive advantage in high UV surface waters
Mengelt, C., & Prézelin, B. (2005) · Marine Ecology Progress Series · doi:10.3354/meps301081 · Cited by 38 · see citing works
Hidden thin layers of toxic diatoms in a coastal bay
Timmerman, A. H. V., McManus, M. A., Cheriton, O. M., Cowen, R. K., Greer, A. T., Kudela, R. M., Ruttenberg, K. C., & Sevadjian, J. C. (2013) · Deep Sea Research Part II Topical Studies in Oceanography · doi:10.1016/j.dsr2.2013.05.030 · Cited by 35 · see citing works
Harmful algae and climate change on the Canadian East Coast: Exploring occurrence predictions of Dinophysis acuminata, D. norvegica, and Pseudo-nitzschia seriata
Boivin-Rioux, A., Starr, M., Chassé, J., Scarratt, M., Perrie, W. A., Long, Z., & Lavoie, D. (2022) · Harmful Algae · doi:10.1016/j.hal.2022.102183 · Cited by 35 · see citing works
Hollow nanogold microsphere-signalized lateral flow immunodipstick for the sensitive determination of the neurotoxin brevetoxin B
Zhang, K., Wu, J., Li, Y., Wu, Y., Huang, T., & Tang, D. (2014) · Microchimica Acta · doi:10.1007/s00604-014-1291-9 · Cited by 33 · see citing works
Adsorption and Activity of a Domoic Acid Binding Antibody Fragment on Mesoporous Silicates
Hu, X., Spada, S., White, S. J., Hudson, S. P., Magner, E., & Wall, J. G. (2006) · The Journal of Physical Chemistry B · doi:10.1021/jp062423e · Cited by 33 · see citing works
Development and validation of the first high performance-lateral flow immunoassay (HP-LFIA) for the rapid screening of domoic acid from shellfish extracts
Jawaid, W., Meneely, J. P., Campbell, K., Hooper, M., Melville, K., Holmes, S. J., Rice, J., & Elliott, C. T. (2013) · Talanta · doi:10.1016/j.talanta.2013.07.027 · Cited by 33 · see citing works
Characterization of Renal Toxicity in Mice Administered the Marine Biotoxin Domoic Acid
Funk, J. A., Janech, M. G., Dillon, J. C., Bissler, J. J., Siroky, B. J., & Bell, P. D. (2014) · Journal of the American Society of Nephrology · doi:10.1681/asn.2013080836 · Cited by 32 · see citing works
Development of a Sensitive Enzyme-Linked Immunosorbent Assay for the Determination of Domoic Acid in Shellfish
Yu, F., Liu, B.-H., Wu, T., Chi, T.-F., & Su, M. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf049303t · Cited by 31 · see citing works
Common European harmful algal blooms affect the viability and innate immune responses of Mytilus edulis larvae
Rijcke, M. D., Vandegehuchte, M., Bussche, J. V., Nevejan, N. M., Vanhaecke, L., Schamphelaere, K. D., & Janssen, C. (2015) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2015.09.003 · Cited by 30 · see citing works
Degradation of domoic acid toxin by UV-promoted Fenton-like processes in seawater
Bandala, E. R., Brito, L., & Peláez, M. A. (2009) · Desalination · doi:10.1016/j.desal.2008.06.015 · Cited by 30 · see citing works
Release and degradation of amnesic shellfish poison from decaying Pseudo-nitzschia multiseries in presence of bacteria and organic matter
Hagström, J. A., Granéli, E., Maneiro, I., Barreiro, A., Petermann, A., & Svensen, C. (2006) · Harmful Algae · doi:10.1016/j.hal.2006.08.002 · Cited by 30 · see citing works
Shelf sea subsurface chlorophyll maximum thin layers have a distinct phytoplankton community structure
Barnett, M. L., Kemp, A. E. S., Hickman, A. E., & Purdie, D. A. (2018) · Continental Shelf Research · doi:10.1016/j.csr.2018.12.007 · Cited by 29 · see citing works
The sexual phase of the diatom Pseudo-nitzschia multistriata: cytological and time-lapse cinematography characterization
Scalco, E., Amato, A., Ferrante, M. I., & Montresor, M. (2015) · PROTOPLASMA · doi:10.1007/s00709-015-0891-5 · Cited by 28 · see citing works
Multipoint recognition of domoic acid from seawater by dummy template molecularly imprinted solid-phase extraction coupled with high-performance liquid chromatography
He, X., Chen, J., Wang, J., & Tan, L. (2017) · Journal of Chromatography A · doi:10.1016/j.chroma.2017.04.023 · Cited by 27 · see citing works
Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
Jing, J., Petroff, R., Shum, S., Crouthamel, B., Topletz, A. R., Grant, K. S., Burbacher, T. M., & Isoherranen, N. (2017) · Drug Metabolism and Disposition · doi:10.1124/dmd.117.078485 · Cited by 27 · see citing works
Variability of Amnesic Shellfish Toxin and Pseudo-nitzschia occurrence in bivalve molluscs and water samples–Analysis of ten years of the official control monitoring programme
Rowland-Pilgrim, S. J., Swan, S., O’Neill, A., Johnson, S., Coates, L., Stubbs, P., Dean, K. J., Parks, R., Harrison, K., Alves, M. T., et al. (2019) · Harmful Algae · doi:10.1016/j.hal.2019.101623 · Cited by 27 · see citing works
Growth and domoic acid content of Pseudo-nitzschia australis isolated from northwestern Baja California, Mexico, cultured under batch conditions at different temperatures and two Si:NO3 ratios
Santiago-Morales, I. S., & Mendoza, E. G. (2011) · Harmful Algae · doi:10.1016/j.hal.2011.09.004 · Cited by 27 · see citing works
Adsorption of domoic acid to marine sediments and clays
Burns, J. M., & Ferry, J. L. (2007) · Journal of Environmental Monitoring · doi:10.1039/b713101a · Cited by 27 · see citing works
Bacterial involvement in determining domoic acid levels in Pseudo-nitzschia multiseries cultures
Stewart, J. (2007) · Aquatic Microbial Ecology · doi:10.3354/ame01159 · Cited by 26 · see citing works
GENETIC POPULATION STRUCTURE OF PSEUDO‐NITZSCHIA PUNGENS (BACILLARIOPHYCEAE) FROM THE PACIFIC NORTHWEST AND THE NORTH SEA1
Adams, N. G., Trainer, V. L., Rocap, G., Herwig, R. P., & Hauser, L. (2009) · Journal of Phycology · doi:10.1111/j.1529-8817.2009.00746.x · Cited by 25 · see citing works
A Generic LC-HRMS Screening Method for Marine and Freshwater Phycotoxins in Fish, Shellfish, Water, and Supplements
Klijnstra, M. D., Faassen, E. J., & Gerssen, A. (2021) · Toxins · doi:10.3390/toxins13110823 · Cited by 24 · see citing works
Domoic acid at trace levels in lagoon waters: assessment of a method using internal standard quantification
Barbaro, E., Zangrando, R., Rossi, S., Cairns, W. R. L., Piazza, R., Corami, F., Barbante, C., & Gambaro, A. (2013) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-013-7348-5 · Cited by 24 · see citing works
Discovery of Bioactive Metabolites in Biofuel Microalgae That Offer Protection against Predatory Bacteria
Bagwell, C. E., Abernathy, A., Barnwell, R., Milliken, C. E., Noble, P. A., Dale, T., Beauchesne, K. R., & Moeller, P. D. R. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00516 · Cited by 24 · see citing works
First report of Pseudo-nitzschia brasiliana and P. micropora (Bacillariophycea) found in Cuyutlan Lagoon, Mexico
Quijano‐Scheggia, S., Ortiz, A. O., Gaviño-Rodríguez, J. H., Castro-Ochoa, F. Y., Rivera‐Vilarelle, M., Galicia-Pérez, M., & Patiño‐Barragan, M. (2011) · Revista de biología marina y oceanografía · doi:10.4067/s0718-19572011000200008 · Cited by 23 · see citing works
'One toxicology', 'ecosystem health' and 'one health'.
Beasley, V. R. (2009) · PubMed · Cited by 23 · see citing works
Quantification of domoic acid in shellfish samples by capillary electrophoresis-based enzyme immunoassay with electrochemical detection
Zhang, X., & Zhang, Z. (2012) · Toxicon · doi:10.1016/j.toxicon.2012.02.011 · Cited by 22 · see citing works
Marine toxins and nephrotoxicity:Mechanism of injury
Sitprija, V., & Sitprija, S. (2019) · Toxicon · doi:10.1016/j.toxicon.2019.02.012 · Cited by 21 · see citing works
Current Situation of Palytoxins and Cyclic Imines in Asia-Pacific Countries: Causative Phytoplankton Species and Seafood Poisoning
Kim, Y.-S., An, H. J., Kim, J., & Jeon, Y. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19084921 · Cited by 19 · see citing works
Evaluation of intracellular and extracellular domoic acid content in Pseudo-nitzschia multiseries cell cultures under different light regimes
Godinho, L. P., Silva, A., Branco, M. A. C., Marques, A., & Costa, P. R. (2018) · Toxicon · doi:10.1016/j.toxicon.2018.10.003 · Cited by 20 · see citing works
Ultrasonication on a microfluidic chip to lyse single and multiple Pseudo‐nitzschia for marine biotoxin analysis
Wu, C., Lillehoj, P. B., Sabet, L., Wang, P., & Ho, C. (2011) · Biotechnology Journal · doi:10.1002/biot.201000224 · Cited by 18 · see citing works
Presence of the diatom genusPseudo-nitzschiaand particulate domoic acid in the Golden Horn Estuary (Sea of Marmara, Turkey)
Taş, S., Dursun, F., Aksu, A., & Balkıs, N. Ç. (2016) · Diatom Research · doi:10.1080/0269249x.2016.1247020 · Cited by 18 · see citing works
Bacillariophyceae (Diatoms)
Kornprobst, J. (2014) · Wiley eBooks · doi:10.1002/9783527335855.marprod009 · Cited by 19 · see citing works
Improved Detection of Domoic Acid Using Covalently Immobilised Antibody Fragments
Hortigüela, M. J., & Wall, J. G. (2013) · Marine Drugs · doi:10.3390/md11030881 · Cited by 16 · see citing works
Bimolecular Rate Constant Determination for the Reaction of Hydroxyl Radicals with Domoic and Kainic Acid in Aqueous Solution
Jones, K. G., Cooper, W. J., & Mezyk, S. P. (2009) · Environmental Science & Technology · doi:10.1021/es901128c · Cited by 15 · see citing works
HARMFUL MICROALGAE ASSEMBLAGE IN THE AQUACULTURE AREA OF AMAN ISLAND, NORTHEN STRAIT OF MALACCA
Razali, R. M., Leaw, C. P., Hong, C. L., Lim, P. T., Lee, N., & Ishak, I. (2015) · Malaysian Journal of Science · doi:10.22452/mjs.vol34no1.3 · Cited by 14 · see citing works
Marine-Based Toxins and Their Health Risk
Özoğul, F., & Hamed, I. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811442-1.00003-1 · Cited by 14 · see citing works
Exposure to oil from the 2015 Refugio spill alters the physiology of a common harmful algal bloom species, Pseudo-nitzschia australis, and the ubiquitous coccolithophore, Emiliania huxleyi
Ladd, T. M., Bullington, J. A., Matson, P. G., Kudela, R. M., & Iglesias-Rodríguez, M. I. (2018) · Marine Ecology Progress Series · doi:10.3354/meps12710 · Cited by 14 · see citing works
A Rapid LC-HRMS Method for the Determination of Domoic Acid in Urine Using a Self-Assembly Pipette Tip Solid-Phase Extraction
Zhang, Y., Chen, D., & Hong, Z. (2015) · Toxins · doi:10.3390/toxins8010010 · Cited by 13 · see citing works
Domoic Acid: A Review of Its Cytogenotoxicity Within the One Health Approach
Gajski, G., Gerić, M., Baričević, A., & Tanković, M. S. (2024) · Antioxidants · doi:10.3390/antiox13111366 · Cited by 12 · see citing works
Behavioural effects in mice orally exposed to domoic acid or ibotenic acid are influenced by developmental stages and sex differences
Sasaki, T., Saito, H., Hiradate, Y., Hara, K., & Tanemura, K. (2021) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2021.04.080 · Cited by 13 · see citing works
ANALYSIS OF IMPORTANT FRESHWATER AND MARINE TOXINS
Pravda, M., Kreuzer, M. P., & Guilbault, G. G. (2002) · Analytical Letters · doi:10.1081/al-120002357 · Cited by 12 · see citing works
Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia)
Tanković, M. S., Baričević, A., Gerić, M., Domijan, A., Pfannkuchen, D. M., Kužat, N., Ujević, I., Kuralić, M., Rožman, M., Matković, K., et al. (2022) · Environmental Research · doi:10.1016/j.envres.2022.114108 · Cited by 11 · see citing works
Testing the vulnerability of juvenile sea bass (Dicentrarchus labrax) exposed to the harmful algal bloom (HAB) species Pseudo-nitzschia delicatissima
Delegrange, A., Vincent, D., Courcot, L., & Amara, R. (2014) · Aquaculture · doi:10.1016/j.aquaculture.2014.11.023 · Cited by 11 · see citing works
Fast and Sensitive Method for Determination of Domoic Acid in Mussel Tissue
Barbaro, E., Zangrando, R., Barbante, C., & Gambaro, A. (2016) · The Scientific World JOURNAL · doi:10.1155/2016/8404092 · Cited by 10 · see citing works
Non-resonance micro-Raman spectroscopic studies on crystalline domoic acid and its aqueous solutions
Djaoued, Y., Balaji, S., & Priya, S. (2006) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2006.10.025 · Cited by 10 · see citing works
Growth, chain formation, and toxin production by southern Brazilian Pseudo-nitzschia isolates under laboratory conditions
Wadt, P. R., Mafra, L. L., Tavares, C. P. D. S., Fernandes, L. F., & Proença, L. A. D. O. (2017) · Environmental Monitoring and Assessment · doi:10.1007/s10661-017-6301-z · Cited by 10 · see citing works
Ion channels in key marine invertebrates; their diversity and potential for applications in biotechnology
Brown, E. R., & Piscopo, S. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.05.007 · Cited by 9 · see citing works
Toxic Diatom Pseudo-nitzschia and Its Primary Consumers (Vectors)
Bargu, S., Smith, E. A., & Özhan, K. (2011) · Cellular origin and life in extreme habitats · doi:10.1007/978-94-007-1327-7_22 · Cited by 8 · see citing works
Marine toxin domoic acid induces in vitro genomic alterations in human peripheral blood cells
Gajski, G., Gerić, M., Domijan, A., Golubović, I., & Žegura, B. (2020) · Toxicon · doi:10.1016/j.toxicon.2020.08.024 · Cited by 8 · see citing works
Diet–brain connections: role of neurotoxicants
Costa, L. G., Guizzetti, M., & Vitalone, A. (2005) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2004.12.001 · Cited by 8 · see citing works
Direct effects of the algal toxin, domoic acid, on ovarian function: Bovine granulosa and theca cells as an in vitro model
Pizzo, F., Caloni, F., Schreiber, N. B., Schütz, L. F., Totty, M. L., Albonico, M., & SPICER, L. J. (2014) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2014.12.009 · Cited by 8 · see citing works
Description ofPseudo-nitzschia cuspidatavar.manzanillensisvar. nov. (Bacillariophyceae): morphology and molecular characterization of a variety from the central Mexican pacific
Rivera‐Vilarelle, M., Valdez-Velázquez, L. L., & Quijano‐Scheggia, S. (2018) · Diatom Research · doi:10.1080/0269249x.2018.1426633 · Cited by 8 · see citing works
Simultaneous Pre-Concentration and HPLC-MS/MS Quantification of Phycotoxins and Cyanotoxins in Inland and Coastal Waters
Merlo, F., Maraschi, F., Piparo, D., Profumo, A., & Speltini, A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17134782 · Cited by 8 · see citing works
Global Perspectives on Wildlife Toxicology Emerging Issues
Smith, P. N., Afzal, M., Al-Hasan, R. H., Bouwman, H., Castillo, L. E., Depledge, M. H., Subramanian, M., Dhananjayan, V., Fossi, C., Kitulagodage, M., et al. (2010) · CRC Press eBooks · doi:10.1201/9781439817957-c8 · Cited by 7 · see citing works
Proliferative effect of the phycotoxin domoic acid on cancer cell lines: a preliminary evaluation
Ayed, Y., Kouidhi, B., Kassim, S., & Bacha, H. (2018) · Journal of Taibah University for Science · doi:10.1080/16583655.2018.1451107 · Cited by 7 · see citing works
Indoor pollution and human health
Sahoo, G., Wani, A. M., Swamy, S. L., Rout, S., & Gupta, S. (2022) · AIP conference proceedings · doi:10.1063/5.0070902 · Cited by 6 · see citing works
Rapid determination of domoic acid in seafood by fluorescence polarization immunoassay using a portable analyzer
Ogura, Y., Fukuyama, M., Kasuya, M., Shigemura, K., Eremin, S. A., Tokeshi, M., & Hibara, A. (2023) · Analytical Sciences · doi:10.1007/s44211-023-00413-6 · Cited by 6 · see citing works
SEAFOOD TOXINS AND POISONINGS
Kılınç, B. (2015) · Istanbul University Journal of Fisheries & Aquatic Sciences · doi:10.18864/iujfas.60084 · Cited by 5 · see citing works
FOOD CONSTITUENTS AND CONTAMINANTS
Rodricks, J. V., Turnbull, D., Chowdhury, F., & Wu, F. (2020) · doi:10.1002/9781119438922.ch6 · Cited by 5 · see citing works
Can offshore HABs hinder the development of offshore mussel aquaculture in the northeast United States?
Mizuta, D. D., & Wikfors, G. H. (2019) · Ocean & Coastal Management · doi:10.1016/j.ocecoaman.2019.105022 · Cited by 4 · see citing works
Selective liquid chromatographic determination of trace domoic acid in seawater and phytoplankton: improvement using the o‐phthaldialdehyde/9‐fluorenylmethylchloroformate derivatization
Devez, A., & Delmas, D. (2013) · Limnology and Oceanography Methods · doi:10.4319/lom.2013.11.327 · Cited by 4 · see citing works
Is Ocean Fertilization a Good Carbon Sequestration Option
Adhiya, J., & Chisholm, S. W. (2001) · Cited by 4 · see citing works
Toxicology of Global Warming
Zeliger, H. I. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-3463-8.00037-0 · Cited by 3 · see citing works

Potencijalno toksičan rod dijatomeja Pseudo-nitzschia u Jadranskom moru
Gazić, M. (2009)
The effects of nutrient limitation on toxin production for the harmful algal bloom species, Pseudo-nitzschia, in the Gulf of Maine
Park, J. M. (2018) · Digital Commons - Colby (Colby College)
Characterization of a toxic Pseudo-nitzschia spp. bloom in the Northern Gulf of Mexico associated with domoic acid accumulation in fish
Liefer, J. D., Robertson, A., MacIntyre, H. L., Smith, W. L., & Dorsey, C. P. (2013) · Harmful Algae · doi:10.1016/j.hal.2013.03.002 · Cited by 42 · see citing works
New tools and insight for recognition of pseudo-nitzschia bloom and toxin incidence
Quay, J. E. (2011)
A decade and a half of Pseudo-nitzschia spp. and domoic acid along the coast of southern California
Smith, J. L., Connell, P. E., Evans, R. H., Gellene, A. G., Howard, M. D. A., Jones, B. H., Kaveggia, S., Palmer, L., Schnetzer, A., Seegers, B. N., et al. (2018) · Harmful Algae · doi:10.1016/j.hal.2018.07.007 · Cited by 84 · see citing works

Authors: Mos, L.
Affiliations: Wageningen University & Research (NL)
Corresponding author: Mos, Lizzy
Venue: Environmental Toxicology and Pharmacology
Publisher: Elsevier BV
Published: 2001-01
Volume: 9
Issue: 3
Pages: 79-85
ISSN: 1382-6689 (ISSN-L)
DOI: 10.1016/s1382-6689(00)00065-x
OpenAlex: W2134695443
Cited by: 129
References: 50
Citations by year: 2026: 2 · 2025: 2 · 2024: 1 · 2023: 4 · 2022: 7 · 2021: 4 · 2020: 4 · 2019: 4 · 2018: 9 · 2017: 7 · 2016: 5 · 2015: 10 · 2014: 8 · 2013: 6 · 2012: 6
FWCI: 3.40
Type: journal article
Language: en
Open access: green
research.wur.nl
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Environmental Toxicology and Pharmacology (publishedVersion)
PubMed (publishedVersion)
Socio-Environmental Systems Modeling (acceptedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Topics: Physical Sciences › Environmental Science › Environmental Chemistry › Marine Toxins and Detection Methods
Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal ecosystems
Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
Keywords: domoic acid, Pseudo-nitzschia, harmful algal blooms, marine biotoxins, silicon limitation, trace metal availability, iron, nutrient availability, seafood contamination, desert dust, global warming, climate change

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Domoic acid: a fascinating marine toxin

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