Cited by 403Epilepsy research and treatmentEEG and Brain-Computer InterfacesSeismology and Earthquake Studies

The DOI matches its Crossref record; 107 of the 107 references it cites were found in a registry or an index.

Diagnostic challenges in epilepsy: seizure under-reporting and seizure detection

Elger, Christian E, Hoppe, Christian·2018·The Lancet Neurology

Open this paper in CoChat — free account

Abstract

Epileptic seizures vary greatly in clinical phenomenology and can markedly affect the patient's quality of life. As therapeutic interventions focus on reduction or elimination of seizures, the accurate documentation of seizure occurrence is essential. However, patient self-evaluation compared with objective evaluation by video-electroencephalography (EEG) monitoring or long-term ambulatory EEG revealed that patients document fewer than 50% of their seizures, on average, and that documentation accuracy varies significantly over time. For good clinical practice in epilepsy, novel and feasible seizure detection techniques for ambulatory long-term use are needed. Generalised tonic-clonic seizures can already be detected reliably by methods that rely on motion recording (eg, surface electromyography). However, the automatic detection of other seizure types, such as complex partial seizures, will require multimodal approaches that combine the measurement of ictal autonomic alterations (eg, heart rate) and of characteristic movement patterns (eg, accelerometry). Innovative and feasible tools for automatic seizure detection are likely to advance both monitoring of the outcome of a treatment in a patient and clinical research in epilepsy.

Integrity signals

Registry

Crossref · 10.1016/s1474-4422(18)30038-3

Cites

107 of 107 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
Fisher, R. S., Boas, W. V. E., Blume, W. T., Elger, C. E., Genton, P., Lee, P., & Engel, J. (2005) · Epilepsia · doi:10.1111/j.0013-9580.2005.66104.x · Cited by 3,678
Self-citation
Comment on Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
Beghi, E., Berg, A. T., Carpio, A., Forsgren, L., Hesdorffer, D. C., Hauser, W. A., Malmgren, K., Shinnar, S., Temkin, N. R., Thurman, D. J., et al. (2005) · Epilepsia · doi:10.1111/j.1528-1167.2005.00273_1.x · Cited by 2,301
Advancements in Noncontact, Multiparameter Physiological Measurements Using a Webcam
Poh, M., McDuff, D., & Picard, R. W. (2010) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2010.2086456 · Cited by 1,514
Prediction of seizure likelihood with a long-term, implanted seizure advisory system in patients with drug-resistant epilepsy: a first-in-man study
Cook, M. J., O'Brien, T. J., Berkovic, S. F., Murphy, M. A., Morokoff, A. P., Fabinyi, G., D'Souza, W. J., Yerra, R., Archer, J. S., Litewka, L., et al. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70075-9 · Cited by 881
Resective Epilepsy Surgery for Drug-Resistant Focal Epilepsy
Jobst, B. C., & Cascino, G. D. (2015) · JAMA · doi:10.1001/jama.2014.17426 · Cited by 666
Ethosuximide, Valproic Acid, and Lamotrigine in Childhood Absence Epilepsy
Glauser, T. A., Cnaan, A., Shinnar, S., Hirtz, D. G., Dlugos, D., Masur, D. M., Clark, P. O., Capparelli, E. V., & Adamson, P. C. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0902014 · Cited by 643
Epilepsy
Hoppe, C., Poepel, A., & Elger, C. E. (2007) · Archives of Neurology · doi:10.1001/archneur.64.11.1595 · Cited by 486
Self-citation
Unobtrusive ambulatory EEG using a smartphone and flexible printed electrodes around the ear
Debener, S., Emkes, R., Vos, M. D., & Bleichner, M. G. (2015) · Scientific Reports · doi:10.1038/srep16743 · Cited by 383
Drug treatment of epilepsy in adults
Schmidt, D., & Schachter, S. C. (2014) · BMJ · doi:10.1136/bmj.g254 · Cited by 327
Brain‐responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy
Geller, E. B., Skarpaas, T. L., Gross, R. E., Goodman, R. R., Barkley, G. L., Bazil, C. W., Berg, M. J., Bergey, G. K., Cash, S. S., Cole, A. J., et al. (2017) · Epilepsia · doi:10.1111/epi.13740 · Cited by 312
Seizure diaries for clinical research and practice: Limitations and future prospects
Fisher, R. S., Blum, D. E., DiVentura, B. D., Vannest, J. J., Hixson, J., Moss, R., Herman, S. T., Fureman, B. E., & French, J. A. (2012) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2012.04.128 · Cited by 303
Wearable, Wireless EEG Solutions in Daily Life Applications: What are we Missing?
Mihajlović, V., Grundlehner, B., Vullers, R. J. M., & Penders, J. (2014) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2014.2328317 · Cited by 293
Patient awareness of seizures
Blum, D. E., Eskola, J., Bortz, J. J., & Fisher, R. S. (1996) · Neurology · doi:10.1212/wnl.47.1.260 · Cited by 281
Brain‐responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas
Jobst, B. C., Kapur, R., Barkley, G. L., Bazil, C. W., Berg, M. J., Bergey, G. K., Boggs, J. G., Cash, S. S., Cole, A. J., DUCHOWNY, M. S., et al. (2017) · Epilepsia · doi:10.1111/epi.13739 · Cited by 247
Ictal tachycardia: The head–heart connection
Eggleston, K. S., Olin, B., & Fisher, R. S. (2014) · Seizure · doi:10.1016/j.seizure.2014.02.012 · Cited by 242
Autonomic changes with seizures correlate with postictal EEG suppression
Poh, M., Loddenkemper, T., Reinsberger, C., Swenson, N. C., Goyal, S., Madsen, J. R., & Picard, R. W. (2012) · Neurology · doi:10.1212/wnl.0b013e318258f7f1 · Cited by 242
Heart rate and EKG changes in 102 seizures: analysis of influencing factors
Opherk, C., Coromilas, J., & Hirsch, L. J. (2002) · Epilepsy Research · doi:10.1016/s0920-1211(02)00215-2 · Cited by 237
Automated seizure detection systems and their effectiveness for each type of seizure
Ulate-Campos, A., Coughlin, F., Gaínza-Lein, M., Fernández, I. S., Pearl, P. L., & Loddenkemper, T. (2016) · Seizure · doi:10.1016/j.seizure.2016.06.008 · Cited by 233
Detection of generalized tonic–clonic seizures by a wireless wrist accelerometer: A prospective, multicenter study
Beniczky, S., Polster, T., Kjaer, T. W., & Hjalgrim, H. (2013) · Epilepsia · doi:10.1111/epi.12120 · Cited by 230
Addressing the burden of epilepsy: Many unmet needs
Beghi, E. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.03.003 · Cited by 163
Automatic Vagus Nerve Stimulation Triggered by Ictal Tachycardia: Clinical Outcomes and Device Performance—The U.S. E-37 Trial
Fisher, R. S., Afra, P., Macken, M. P., Minecan, D. N., Bagic, A. I., Benbadis, S. R., Helmers, S. L., Sinha, S. R., Slater, J. D., Treiman, D. M., et al. (2015) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12376 · Cited by 156
Views of patients with epilepsy on seizure prediction devices
Schulze‐Bonhage, A., Sales, F., Wagner, K., Teotónio, R., Carius, A., Schelle, A., & Ihle, M. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.05.008 · Cited by 155
BioWatch: A Noninvasive Wrist-Based Blood Pressure Monitor That Incorporates Training Techniques for Posture and Subject Variability
Thomas, S. S., Nathan, V., Zong, C., Soundarapandian, K., Shi, X., & Jafari, R. (2015) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2015.2458779 · Cited by 140
Outpatient Seizure Identification
Tatum, W. O., Winters, L., Gieron, M. A., Passaro, E. A., Benbadis, S. R., Ferreira, J. A., & Liporace, J. D. (2001) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-200101000-00004 · Cited by 139
The potential value of three-dimensional accelerometry for detection of motor seizures in severe epilepsy
Nijsen, T. M. E., Arends, J. B. A. M., Griep, P. A. M., & Cluitmans, P. J. M. (2005) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.04.011 · Cited by 139
Multi-Biosignal Analysis for Epileptic Seizure Monitoring
Cogan, D., Birjandtalab, J., Nourani, M., Harvey, J. H., & Nagaraddi, V. (2016) · International Journal of Neural Systems · doi:10.1142/s0129065716500313 · Cited by 124
The role of postictal laboratory blood analyses in the diagnosis and prognosis of seizures
Nass, R. D., Sassen, R., Elger, C. E., & Surges, R. (2017) · Seizure · doi:10.1016/j.seizure.2017.02.013 · Cited by 121
Self-citation
Amplitude-integrated EEG for detection of neonatal seizures: a systematic review
Rakshasbhuvankar, A. A., Paul, S., Nagarajan, L., Ghosh, S., & Rao, S. C. (2015) · Seizure · doi:10.1016/j.seizure.2015.09.014 · Cited by 120
Mobile health: the power of wearables, sensors, and apps to transform clinical trials
Munos, B., Baker, P. C., Bot, B. M., Crouthamel, M., de Vries, G., Ferguson, I., Hixson, J. D., Malek, L. A., Mastrototaro, J. J., Misra, V., et al. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13117 · Cited by 118
Non-EEG seizure detection systems and potential SUDEP prevention: State of the art
de Vel, A. V., Cuppens, K., Bonroy, B., Milošević, M., Jansen, K., Huffel, S. V., Vanrumste, B., Cras, P. P., Lagae, L., & Ceulemans, B. (2016) · Seizure · doi:10.1016/j.seizure.2016.07.012 · Cited by 117
Novel techniques for automated seizure registration: Patients' wants and needs
Hoppe, C., Feldmann, M., Blachut, B., Surges, R., Elger, C. E., & Helmstaedter, C. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.08.006 · Cited by 116
Self-citation
When do patients forget their seizures? An electroclinical study
Kerling, F., Mueller, S., Pauli, E., & Stefan, H. (2006) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2006.05.010 · Cited by 115
Crowdsourcing seizure detection: algorithm development and validation on human implanted device recordings
Baldassano, S. N., Brinkmann, B. H., Ung, H., Blevins, T., Conrad, E. C., Leyde, K. W., Cook, M. J., Khambhati, A. N., Wagenaar, J., Worrell, G. A., et al. (2017) · Brain · doi:10.1093/brain/awx098 · Cited by 113
Heart rate variability analysis indicates preictal parasympathetic overdrive preceding seizure‐induced cardiac dysrhythmias leading to sudden unexpected death in a patient with epilepsy
Jeppesen, J., Fuglsang‐Frederiksen, A., Brugada, R., Pedersen, B., Rubboli, G., Johansen, P., & Beniczky, S. (2014) · Epilepsia · doi:10.1111/epi.12614 · Cited by 111
Detection of generalized tonic–clonic seizures using surface electromyographic monitoring
Halford, J. J., Sperling, M. R., Nair, D. R., Dlugos, D., Tatum, W. O., Harvey, J. H., French, J. A., Pollard, J. R., Faught, E., Noe, K. H., et al. (2017) · Epilepsia · doi:10.1111/epi.13897 · Cited by 110
Seizure frequency in children with epilepsy: Factors influencing accuracy and parental awareness
Akman, Ç. I., Montenegro, M. A., Jacob, S., Eck, K., Chiriboga, C. A., & Gilliam, F. G. (2009) · Seizure · doi:10.1016/j.seizure.2009.05.009 · Cited by 108
Prospective multi-center study of an automatic online seizure detection system for epilepsy monitoring units
Fürbass, F., Ossenblok, P., Hartmann, M., Perko, H., Skupch, A. M., Lindinger, G., Elezi, L., Pataraia, E., Colon, A., Baumgartner, C., et al. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.09.023 · Cited by 104
Detection of epileptic seizures with a modified heart rate variability algorithm based on Lorenz plot
Jeppesen, J., Beniczky, S., Johansen, P., Sidenius, P., & Fuglsang‐Frederiksen, A. (2014) · Seizure · doi:10.1016/j.seizure.2014.11.004 · Cited by 101
Electromyography‐based seizure detector: Preliminary results comparing a generalized tonic–clonic seizure detection algorithm to video‐ EEG recordings
Szabó, C. Á., Morgan, L. C., Karkar, K. M., Leary, L., Lie, O. V., Girouard, M., & Cavazos, J. E. (2015) · Epilepsia · doi:10.1111/epi.13083 · Cited by 94
Safe and sound? A systematic literature review of seizure detection methods for personal use
Jory, C., Shankar, R., Coker, D., McLean, B., Hanna, J., & Newman, C. G. J. (2016) · Seizure · doi:10.1016/j.seizure.2016.01.013 · Cited by 93
Automatic seizure detection in long-term scalp EEG using an adaptive thresholding technique: A validation study for clinical routine
Hopfengärtner, R., Kasper, B. S., Graf, W., Gollwitzer, S., Kreiselmeyer, G., Stefan, H., & Hamer, H. M. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2013.12.104 · Cited by 92
Cross sectional study of reporting of epileptic seizures to general practitioners
Dalrymple, J. (2000) · BMJ · doi:10.1136/bmj.320.7227.94 · Cited by 87
Mobile EEG in epilepsy
Askamp, J., & van Putten, M. J. A. M. (2013) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2013.09.002 · Cited by 86
Assessment of a quasi-piezoelectric mattress monitor as a detection system for generalized convulsions
Narechania, A., Garic, I., Sen‐Gupta, I., Macken, M. P., Gerard, E. E., & Schuele, S. (2013) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.04.017 · Cited by 81
Subjective seizure counts by epilepsy clinical drug trial participants are not reliable
Blachut, B., Hoppe, C., Surges, R., Elger, C. E., & Helmstaedter, C. (2017) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.10.036 · Cited by 81
Self-citation
Lactate as a diagnostic marker in transient loss of consciousness
Matz, O., Zdebik, C., Zechbauer, S., Bündgens, L., Litmathe, J., Willmes, K., Schulz, J. B., & Dafotakis, M. (2016) · Seizure · doi:10.1016/j.seizure.2016.06.014 · Cited by 80
Testing patients during seizures: A European consensus procedure developed by a joint taskforce of the ILAE – Commission on European Affairs and the European Epilepsy Monitoring Unit Association
Beniczky, S., Neufeld, M. Y., Diehl, B., Dobesberger, J., Trinka, E., Mameniškienė, R., Rheims, S., Gil‐Nagel, A., Craiu, D., Pressler, R., et al. (2016) · Epilepsia · doi:10.1111/epi.13472 · Cited by 80
Use of an online epilepsy diary to characterize repetitive seizures
Fisher, R. S., Bartfeld, E., & Cramer, J. A. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.04.022 · Cited by 79
Non-EEG based ambulatory seizure detection designed for home use: What is available and how will it influence epilepsy care?
van Andel, J. M., Thijs, R. D., de Weerd, A., Arends, J. B. A. M., & Leijten, F. S. S. (2016) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.01.003 · Cited by 78
Counting seizures: The primary outcome measure in epileptology from the patients’ perspective
Blachut, B., Hoppe, C., Surges, R., Stähl, J., Elger, C. E., & Helmstaedter, C. (2015) · Seizure · doi:10.1016/j.seizure.2015.03.004 · Cited by 76
Self-citation
Vision-based motion detection, analysis and recognition of epileptic seizures—A systematic review
Pediaditis, M., Tsiknakis, M., & Leitgeb, N. (2012) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2012.08.005 · Cited by 76
Patient-centered design criteria for wearable seizure detection devices
Patel, A. D., Moss, R., Rust, S. W., Patterson, J., Strouse, R., Gedela, S., Haines, J., & Lin, S. M. (2016) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.09.012 · Cited by 72
SmartWatch by SmartMonitor: Assessment of Seizure Detection Efficacy for Various Seizure Types in Children, a Large Prospective Single-Center Study
Patterson, A. L., Mudigoudar, B. D., Fulton, S. P., McGregor, A., Poppel, K. V., Wheless, M. C., Brooks, L., & Wheless, J. W. (2015) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2015.07.002 · Cited by 71
Validation of an automated seizure detection algorithm for term neonates
Mathieson, S., Stevenson, N. J., Low, E., Marnane, W. P., Rennie, J. M., Temko, A., Lightbody, G., & Boylan, G. B. (2015) · Clinical Neurophysiology · doi:10.1016/j.clinph.2015.04.075 · Cited by 69
Patients’ safety in the epilepsy monitoring unit
Rheims, S., & Ryvlin, P. (2014) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000076 · Cited by 69
Awareness and Responsiveness During Partial Seizures
Inoue, Y., & Mihara, T. (1998) · Epilepsia · doi:10.1111/j.1528-1157.1998.tb05142.x · Cited by 68
Accelerometry-Based Home Monitoring for Detection of Nocturnal Hypermotor Seizures Based on Novelty Detection
Cuppens, K., Karsmakers, P., Van de Vel, A., Bonroy, B., Milosevic, M., Luca, S., Croonenborghs, T., Ceulemans, B., Lagae, L., Van Huffel, S., et al. (2014) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2013.2285015 · Cited by 66
Tracking generalized tonic-clonic seizures with a wrist accelerometer linked to an online database
Velez, M., Fisher, R. S., Bartlett, V., & Le, S. (2016) · Seizure · doi:10.1016/j.seizure.2016.04.009 · Cited by 65
Wrist sensor reveals sympathetic hyperactivity and hypoventilation before probable SUDEP
Picard, R. W., Migliorini, M., Caborni, C., Onorati, F., Regalia, G., Friedman, D. J., & Devinsky, O. (2017) · Neurology · doi:10.1212/wnl.0000000000004208 · Cited by 65
Automated non-EEG based seizure detection: Do users have a say?
de Vel, A. V., Smets, K., Wouters, K., & Ceulemans, B. (2016) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.06.029 · Cited by 63
AUTOMATED SEIZURE DETECTION USING EKG
Osorio, I. (2013) · International Journal of Neural Systems · doi:10.1142/s0129065714500014 · Cited by 62
Non-expert use of quantitative EEG displays for seizure identification in the adult neuro-intensive care unit
Dericioğlu, N., Yetim, E., Baş, D. F., Bilgen, N., Caglar, G., Arsava, E. M., & Topçuoğlu, M. A. (2014) · Epilepsy Research · doi:10.1016/j.eplepsyres.2014.10.013 · Cited by 61
Automatic multimodal detection for long-term seizure documentation in epilepsy
Fürbass, F., Kampusch, S., Kaniušas, E., Koren, J. P., Pirker, S., Hopfengärtner, R., Stefan, H., Kluge, T., & Baumgartner, C. (2017) · Clinical Neurophysiology · doi:10.1016/j.clinph.2017.05.013 · Cited by 61
Seizure prediction and documentation—two important problems
Elger, C. E., & Mormann, F. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70092-9 · Cited by 58
Self-citation
Effect of epileptic seizures on the cerebrospinal fluid–A systematic retrospective analysis.
Tumani, H., Jobs, C., Brettschneider, J., Hoppner, A. C., Kerling, F., & Fauser, S. (2015) · Epilepsy Research · doi:10.1016/j.eplepsyres.2015.04.004 · Cited by 57
Pre- and postictal, not ictal, heart rate distinguishes complex partial and psychogenic nonepileptic seizures
Reinsberger, C., Perez, D. L., Murphy, M. M., & Dworetzky, B. A. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2011.10.008 · Cited by 56
Patient and caregiver view on seizure detection devices: A survey study
Quiroga, D. F. T., Britton, J. W., & Wirrell, E. C. (2016) · Seizure · doi:10.1016/j.seizure.2016.08.004 · Cited by 55
Automatic multi-modal intelligent seizure acquisition (MISA) system for detection of motor seizures from electromyographic data and motion data
Conradsen, I., Beniczky, S., Wolf, P., Kjær, T. W., Sams, T., & Sørensen, H. B. D. (2011) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2011.06.005 · Cited by 53
Seizure‐related modulation of systemic arterial blood pressure in focal epilepsy
Hampel, K. G., Jahanbekam, A., Elger, C. E., & Surges, R. (2016) · Epilepsia · doi:10.1111/epi.13504 · Cited by 52
Self-citation
Google Home: smart speaker as environmental control unit
Noda, K. (2017) · Disability and Rehabilitation Assistive Technology · doi:10.1080/17483107.2017.1369589 · Cited by 52
The value of home video with ambulatory EEG: a prospective service review
Goodwin, E., Kandler, R. H., & Alix, J. J. P. (2014) · Seizure · doi:10.1016/j.seizure.2014.02.008 · Cited by 51
Clinical implementation of a neonatal seizure detection algorithm
Temko, A., Marnane, W. P., Boylan, G. B., & Lightbody, G. (2014) · Decision Support Systems · doi:10.1016/j.dss.2014.12.006 · Cited by 51
Video ambulatory EEG: A good alternative to inpatient video telemetry?
Kandler, R., Ponnusamy, A., & Wragg, C. (2017) · Seizure · doi:10.1016/j.seizure.2017.02.010 · Cited by 50
Seizure prediction and recall
DuBois, J. M., Boylan, L. S., Shiyko, M., Barr, W., & Devinsky, O. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.03.011 · Cited by 49
Quantitative analysis of surface electromyography during epileptic and nonepileptic convulsive seizures
Beniczky, S., Conradsen, I., Moldovan, M., Jennum, P., Fabricius, M. E., Benedek, K., Andersen, N., Hjalgrim, H., & Wolf, P. (2014) · Epilepsia · doi:10.1111/epi.12669 · Cited by 49
Can heart rate variability in children with epilepsy be used to predict seizures?
Kolsal, E., Serdaroğlu, A., Çilsal, E., Kula, S., Soysal, A. Ş., Kurt, A. N. Ç., & Arhan, E. (2014) · Seizure · doi:10.1016/j.seizure.2014.01.025 · Cited by 49
Prospective Study of 2 Bed Alarms for Detection of Nocturnal Seizures
Fulton, S. P., Poppel, K. V., McGregor, A., Ellis, M., Patters, A. B., & Wheless, J. W. (2012) · Journal of Child Neurology · doi:10.1177/0883073812462064 · Cited by 47
Long‐term monitoring of cardiorespiratory patterns in drug‐resistant epilepsy
Goldenholz, D. M., Kuhn, A., Austermuehle, A., Bachler, M., Mayer, C. C., Wassertheurer, S., Inati, S. K., & Theodore, W. H. (2016) · Epilepsia · doi:10.1111/epi.13606 · Cited by 47
Patient awareness of seizures as documented in the epilepsy monitoring unit.
Poochikian-Sarkissian, S., Tai, P. C., del Campo, M., Andrade, D. M., Carlen, P. L., Valiante, T. A., & Wennberg, R. A. (2009) · PubMed · Cited by 46
Exploring the capability of wireless near infrared spectroscopy as a portable seizure detection device for epilepsy patients
Jeppesen, J., Beniczky, S., Johansen, P., Sidenius, P., & Fuglsang‐Frederiksen, A. (2015) · Seizure · doi:10.1016/j.seizure.2015.01.015 · Cited by 45
Seizure detection with automated EEG analysis: A validation study focusing on periodic patterns
Sierra‐Marcos, A., Scheuer, M. L., & Rossetti, A. O. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.06.025 · Cited by 43
Detection of tonic epileptic seizures based on surface electromyography
Larsen, S. N., Conradsen, I., Beniczky, S., & Sørensen, H. B. D. (2014) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2014.6943747 · Cited by 42
Changes in serum miRNAs following generalized convulsive seizures in human mesial temporal lobe epilepsy
Surges, R., Kretschmann, A., Abnaof, K., van Rikxoort, M., Ridder, K. D., Fröhlich, H., Danis, B., Kaminski, R. M., Foerch, P., Elger, C. E., et al. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.11.029 · Cited by 42
Self-citation
Diagnostic accuracy of microEEG: A miniature, wireless EEG device
Grant, A. C., Abdel-Baki, S. G., Omurtag, A., Sinert, R. H., Chari, G., Malhotra, S., Weedon, J., Fenton, A. A., & Zehtabchi, S. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.03.015 · Cited by 41
PureEEG: Automatic EEG artifact removal for epilepsy monitoring
Hartmann, M., Schindler, K. A., Gebbink, T. A., Gritsch, G., & Kluge, T. (2014) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2014.09.001 · Cited by 41
Current practice and recommendations in UK epilepsy monitoring units. Report of a national survey and workshop
Hamandi, K., Beniczky, S., Diehl, B., Kandler, R., Pressler, R., Sen, A., Solomon, J., Walker, M. C., & Bagary, M. S. (2017) · Seizure · doi:10.1016/j.seizure.2017.06.015 · Cited by 41
Quantitative analysis of surface electromyography: Biomarkers for convulsive seizures
Beniczky, S., Conradsen, I., Pressler, R., & Wolf, P. (2016) · Clinical Neurophysiology · doi:10.1016/j.clinph.2016.04.017 · Cited by 40
Epilepsy, unawareness of seizures and driving license: The potential role of 24-hour ambulatory EEG in defining seizure freedom
Fattouch, J., Bonaventura, C. D., Lapenta, L., Casciato, S., Fanella, M., Morano, A., Manfredi, M., & Giallonardo, A. T. (2012) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2012.07.001 · Cited by 34
Critical evaluation of four different seizure detection systems tested on one patient with focal and generalized tonic and clonic seizures
de Vel, A. V., Verhaert, K., & Ceulemans, B. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.06.014 · Cited by 32
Clinical and EEG Estimates of Absence Seizure Frequency
Browne, T. R., Dreifuss, F. E., PENRY, J. K., Porter, R. J., & WHITE, B. G. (1983) · Archives of Neurology · doi:10.1001/archneur.1983.04210070009004 · Cited by 31
What Makes a Good Home-Based Nocturnal Seizure Detector? A Value Sensitive Design
van Andel, J. M., Leijten, F. S. S., van Delden, H., & van Thiel, G. J. M. W. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121446 · Cited by 31
Probability of detection of clinical seizures using heart rate changes
Osorio, I., & Manly, B. F. J. (2015) · Seizure · doi:10.1016/j.seizure.2015.06.007 · Cited by 28
Human bedside evaluation versus automatic responsiveness testing in epilepsy (ARTiE)
Touloumes, G. J., Morse, E., Chen, W. C., Gober, L. M., Dente, J., Lilenbaum, R., Katzenstein, E., Pacelli, A., Johnson, E. A., Si, Y., et al. (2015) · Epilepsia · doi:10.1111/epi.13262 · Cited by 28
Consciousness of seizures and consciousness during seizures: Are they related?
Detyniecki, K., & Blumenfeld, H. (2013) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.09.018 · Cited by 27
Copeptin as a Serum Biomarker of Febrile Seizures
Stöcklin, B., Fouzas, S., Schillinger, P., Cayir, S., Skendaj, R., Ramser, M., Weber, P., & Wellmann, S. M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124663 · Cited by 25
Is seizure detection based on EKG clinically relevant?
Osorio, I., & Manly, B. F. J. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.01.026 · Cited by 24
Long-term accelerometry-triggered video monitoring and detection of tonic–clonic and clonic seizures in a home environment: Pilot study
de Vel, A. V., Milošević, M., Bonroy, B., Cuppens, K., Lagae, L., Vanrumste, B., Huffel, S. V., & Ceulemans, B. (2016) · Epilepsy & Behavior Case Reports · doi:10.1016/j.ebcr.2016.03.005 · Cited by 23
Seizure detection and neuromodulation: A summary of data presented at the XIII conference on new antiepileptic drug and devices (EILAT XIII)
Bialer, M., Johannessen, S. I., Levy, R. H., Perucca, E., Tomson, T., White, H. S., & Koepp, M. J. (2017) · Epilepsy Research · doi:10.1016/j.eplepsyres.2017.01.004 · Cited by 22
Temporal seizure focus and status epilepticus are associated with high-sensitive troponin I elevation after epileptic seizures
Chatzikonstantinou, A., Ebert, A., & Hennerici, M. G. (2015) · Epilepsy Research · doi:10.1016/j.eplepsyres.2015.05.013 · Cited by 21
The relationship between seizure onset zone and ictal tachycardia: An intracranial EEG study
Stefanidou, M., Carlson, C., & Friedman, D. J. (2015) · Clinical Neurophysiology · doi:10.1016/j.clinph.2015.01.020 · Cited by 17
The importance of people compliance (social desirability bias) in the assessment of epilepsy prevalence in rural areas of developing countries. Results of the Atahualpa Project
Brutto, Ó. H. D., Mera, R. M., & the Atahualpa Project Investigators (2016) · Epilepsia · doi:10.1111/epi.13594 · Cited by 17
Sudden unexpected death in epilepsy: measures to reduce risk
McLean, B., Shankar, R., Hanna, J., Jory, C., & Newman, C. G. J. (2016) · Practical Neurology · doi:10.1136/practneurol-2016-001392 · Cited by 17
Epileptic Seizure Detection and Prediction Based on Continuous Cerebral Blood Flow Monitoring – a Review
Tewolde, S. N., Oommen, K. J., Lie, D. Y. C., Zhang, Y., & Chyu, M. (2015) · Journal of Healthcare Engineering · doi:10.1260/2040-2295.6.2.159 · Cited by 16
Statistical modeling of behavioral dynamics during propofol-induced loss of consciousness
Wong, K. F. K., Smith, A. C., Pierce, E. T., Harrell, P. G., Walsh, J. L., Salazar-Gómez, A. F., Tavares, C. L., Purdon, P. L., & Brown, E. N. (2014) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2014.01.026 · Cited by 16
Ictal ipsilateral sweating in focal epilepsy
Franco, A. C. G., Noachtar, S., & Rémi, J. (2017) · Seizure · doi:10.1016/j.seizure.2017.05.009 · Cited by 14
Advances in EEG: home video telemetry, high frequency oscillations and electrical source imaging
Patel, A. C., Thornton, R. C., Mitchell, T. N., & Michell, A. W. (2016) · Journal of Neurology · doi:10.1007/s00415-016-8159-3 · Cited by 8
Biceps electromyography in dialeptic and automotor seizures with and without secondary generalization
Hagge, M., Nunnemann, S., Bauer, S., Gollwitzer, S., Oertel, W. H., Knake, S., Rosenow, F., & Hamer, H. M. (2015) · Clinical Neurophysiology · doi:10.1016/j.clinph.2015.10.034 · Cited by 3

Sorted by citations

Epilepsy in adults
Thijs, R. D., Surges, R., O'Brien, T. J., & Sander, J. W. A. S. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32596-0 · Cited by 2,359
Seizure prediction – ready for a new era
Kuhlmann, L., Lehnertz, K., Richardson, M. P., Schelter, B., & Zaveri, H. P. (2018) · Nature Reviews Neurology · doi:10.1038/s41582-018-0055-2 · Cited by 450
Drug resistance in epilepsy
Perucca, E., Perucca, P., White, H. S., & Wirrell, E. C. (2023) · The Lancet Neurology · doi:10.1016/s1474-4422(23)00151-5 · Cited by 342
Cycles in epilepsy
Karoly, P. J., Rao, V. R., Gregg, N. M., Worrell, G. A., Bernard, C., Cook, M. J., & Baud, M. O. (2021) · Nature Reviews Neurology · doi:10.1038/s41582-021-00464-1 · Cited by 275
Seizure Cycles in Focal Epilepsy
Leguia, M. G., Andrzejak, R. G., Rummel, C., Fan, J. M., Mirro, E. A., Tcheng, T. K., Rao, V. R., & Baud, M. O. (2021) · JAMA Neurology · doi:10.1001/jamaneurol.2020.5370 · Cited by 185

See all 403

Authors: Elger, C. E., & Hoppe, C.
Affiliations: University of Bonn (DE)
Corresponding author: Hoppe, Christian
ORCID: Elger, Christian E
Hoppe, Christian
Venue: The Lancet Neurology
Publisher: Elsevier BV
Published: 2018-03
Volume: 17
Issue: 3
Pages: 279-288
ISSN: 1474-4422 (ISSN-L)
DOI: 10.1016/s1474-4422(18)30038-3
OpenAlex: W2787779804
Cited by: 403
References: 107
Citations by year: 2026: 39 · 2025: 57 · 2024: 76 · 2023: 53 · 2022: 56 · 2021: 45 · 2020: 41 · 2019: 26 · 2018: 10
FWCI: 4.64
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet Neurology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
Physical Sciences › Computer Science › Artificial Intelligence › Seismology and Earthquake Studies
Keywords: epilepsy, seizure detection, video-EEG monitoring, ambulatory EEG, generalized tonic-clonic seizures, complex partial seizures, surface electromyography, accelerometry, heart rate, automated seizure detection, treatment outcome monitoring
MeSH terms: Electroencephalography, Epilepsy, Humans, Monitoring, Physiologic, Movement

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Diagnostic challenges in epilepsy: seizure under-reporting and seizure detection

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks