Automated seizure detection systems and their effectiveness for each type of seizure
Open accessAbstract
Epilepsy affects almost 1% of the population and most of the approximately 20-30% of patients with refractory epilepsy have one or more seizures per month. Seizure detection devices allow an objective assessment of seizure frequency and a treatment tailored to the individual patient. A rapid recognition and treatment of seizures through closed-loop systems could potentially decrease morbidity and mortality in epilepsy. However, no single detection device can detect all seizure types. Therefore, the choice of a seizure detection device should consider the patient-specific seizure semiologies. This review of the literature evaluates seizure detection devices and their effectiveness for different seizure types. Our aim is to summarize current evidence, offer suggestions on how to select the most suitable seizure detection device for each patient and provide guidance to physicians, families and researchers when choosing or designing seizure detection devices. Further, this review will guide future prospective validation studies.
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Seizure monitoring, compared to many other clinical applications, requires a high temporal resolution, as seizures can be as short as a few seconds.
“Seizure monitoring, compared to many other clinical applications, requires a high temporal resolution, as seizures can be as short as a few seconds17–19”
From Data quality evaluation in wearable monitoring (2022) · cites this paper as [19]
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Early Identification of Refractory Epilepsy
Kwan, P., & Brodie, M. J. (2000) · New England Journal of Medicine · doi:10.1056/nejm200002033420503 · Cited by 5,204 · see citing works
Fisher, R. S., Boas, W. V. E., Blume, W. T., Elger, C. E., Genton, P., Lee, P., & Engel, J. (2005) · Epilepsia · doi:10.1111/j.0013-9580.2005.66104.x · Cited by 3,678 · see citing works
Beghi, E., Berg, A. T., Carpio, A., Forsgren, L., Hesdorffer, D. C., Hauser, W. A., Malmgren, K., Shinnar, S., Temkin, N. R., Thurman, D. J., et al. (2005) · Epilepsia · doi:10.1111/j.1528-1167.2005.00273_1.x · Cited by 2,301 · see citing works
The descriptive epidemiology of epilepsy—A review
Banerjee, P. N., Filippi, D., & Hauser, W. A. (2009) · Epilepsy Research · doi:10.1016/j.eplepsyres.2009.03.003 · Cited by 927 · see citing works
Cook, M. J., O'Brien, T. J., Berkovic, S. F., Murphy, M. A., Morokoff, A. P., Fabinyi, G., D'Souza, W. J., Yerra, R., Archer, J. S., Litewka, L., et al. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70075-9 · Cited by 881 · see citing works
The epidemiology of epilepsy revisited
Sander, J. W. A. S. (2003) · Current Opinion in Neurology · doi:10.1097/01.wco.0000063766.15877.8e · Cited by 868 · see citing works
Blume, W. T., Lüders, H. O., Mizrahi, E. M., Tassinari, C. A., Boas, W. V. E., & Engel, J. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.22001.x · Cited by 865 · see citing works
The epidemiology of epilepsy in Europe – a systematic review
Forsgren, L., Beghi, E., Õun, A., & Sillanpää, M. L. (2005) · European Journal of Neurology · doi:10.1111/j.1468-1331.2004.00992.x · Cited by 795 · see citing works
Blood pressure and heart rate variabilities in normotensive and hypertensive human beings.
Mancia, G., Ferrari, A. U., Gregorini, L., Parati, G., Pomidossi, G. A., Bertinieri, G., Grassi, G. M., Rienzo, M. D., Pedotti, A., & Zanchetti, A. (1983) · Circulation Research · doi:10.1161/01.res.53.1.96 · Cited by 770 · see citing works
A Wearable Sensor for Unobtrusive, Long-Term Assessment of Electrodermal Activity
Poh, M.-Z., Swenson, N. C., & Picard, R. W. (2010) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2009.2038487 · Cited by 693 · see citing works
Ethosuximide, Valproic Acid, and Lamotrigine in Childhood Absence Epilepsy
Glauser, T. A., Cnaan, A., Shinnar, S., Hirtz, D. G., Dlugos, D., Masur, D. M., Clark, P. O., Capparelli, E. V., & Adamson, P. C. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0902014 · Cited by 643 · see citing works
Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma
Löscher, W., & Schmidt, D. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2011.03024.x · Cited by 593 · see citing works
Incidence, prevalence and aetiology of seizures and epilepsy in children
CAMFIELD, P. R., & Camfield, C. (2015) · Epileptic Disorders · doi:10.1684/epd.2015.0736 · Cited by 507 · see citing works
Hoppe, C., Poepel, A., & Elger, C. E. (2007) · Archives of Neurology · doi:10.1001/archneur.64.11.1595 · Cited by 486 · see citing works
Seizure detection, seizure prediction, and closed-loop warning systems in epilepsy
Ramgopal, S., Thome-Souza, S., Jackson, M., Kadish, N. E., Sánchez Fernández, I., Klehm, J., Bosl, W., Reinsberger, C., Schachter, S., & Loddenkemper, T. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.06.023 · Cited by 469 · see citing works
Self-citationLangan, Y. M., Nashef, L. A. M., & Sander, J. W. A. S. (2005) · Neurology · doi:10.1212/01.wnl.0000156352.61328.cb · Cited by 434 · see citing works
Wearable Electroencephalography
Casson, A. J., Yates, D. C., Smith, S. J. M., Duncan, J. S., & Rodriguez–Villegas, E. (2010) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2010.936545 · Cited by 406 · see citing works
Seizure prediction with spectral power of EEG using cost-sensitive support vector machines
Park, Y., Luo, L., Parhi, K. K., & Netoff, T. I. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2011.03138.x · Cited by 398 · see citing works
Epidemiology, aetiology, and clinical management of epilepsy in Asia: a systematic review
Mac, T. L., Tran, D.-S., Quet, F., Odermatt, P., Preux, P., & Tan, C. T. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70127-8 · Cited by 330 · see citing works
Sudden unexpected death in epilepsy: people with nocturnal seizures may be at highest risk
Lamberts, R. J., Thijs, R. D., Laffan, A., Langan, Y., & Sander, J. W. (2012) · Epilepsia · doi:10.1111/j.1528-1167.2011.03360.x · Cited by 322 · see citing works
Zijlmans, M., Flanagan, D., & Gotman, J. (2002) · Epilepsia · doi:10.1046/j.1528-1157.2002.37801.x · Cited by 316 · see citing works
Electrocardiographic Changes at the Onset of Epileptic Seizures
Leutmezer, F., Schernthaner, C., Lurger, S., Pötzelberger, K., & Baumgartner, C. (2003) · Epilepsia · doi:10.1046/j.1528-1157.2003.34702.x · Cited by 314 · see citing works
Epilepsy and the quality of everyday life
Jacoby, A. (1992) · Social Science & Medicine · doi:10.1016/0277-9536(92)90193-t · Cited by 305 · see citing works
Wearable, Wireless EEG Solutions in Daily Life Applications: What are we Missing?
Mihajlović, V., Grundlehner, B., Vullers, R. J. M., & Penders, J. (2014) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2014.2328317 · Cited by 293 · see citing works
Automatic seizure detection: improvements and evaluation
Gotman, J. (1990) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(90)90032-f · Cited by 291 · see citing works
Blum, D. E., Eskola, J., Bortz, J. J., & Fisher, R. S. (1996) · Neurology · doi:10.1212/wnl.47.1.260 · Cited by 281 · see citing works
Glauser, T. A., Cnaan, A., Shinnar, S., Hirtz, D. G., Dlugos, D., Masur, D. M., Clark, P. O., Adamson, P. C., & for the Childhood Absence Epilepsy Study Team (2012) · Epilepsia · doi:10.1111/epi.12028 · Cited by 272 · see citing works
Convulsive seizure detection using a wrist‐worn electrodermal activity and accelerometry biosensor
Poh, M., Loddenkemper, T., Reinsberger, C., Swenson, N. C., Goyal, S., Sabtala, M. C., Madsen, J. R., & Picard, R. W. (2012) · Epilepsia · doi:10.1111/j.1528-1167.2012.03444.x · Cited by 272 · see citing works
Self-citationEpileptic seizure prediction using relative spectral power features
Bandarabadi, M., Teixeira, C., Rasekhi, J., & Dourado, A. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.05.022 · Cited by 264 · see citing works
Nashef, L. A. M., Fish, D. R., Sander, J. W. A. S., & Shorvon, S. D. (1995) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.58.4.462 · Cited by 261 · see citing works
Validation of heart rate extraction using video imaging on a built-in camera system of a smartphone
Kwon, S., Kim, H.-S., & Park, K. S. (2012) · doi:10.1109/embc.2012.6346392 · Cited by 247 · see citing works
Autonomic changes with seizures correlate with postictal EEG suppression
Poh, M., Loddenkemper, T., Reinsberger, C., Swenson, N. C., Goyal, S., Madsen, J. R., & Picard, R. W. (2012) · Neurology · doi:10.1212/wnl.0b013e318258f7f1 · Cited by 242 · see citing works
Self-citationHeart rate and EKG changes in 102 seizures: analysis of influencing factors
Opherk, C., Coromilas, J., & Hirsch, L. J. (2002) · Epilepsy Research · doi:10.1016/s0920-1211(02)00215-2 · Cited by 237 · see citing works
Beniczky, S., Polster, T., Kjaer, T. W., & Hjalgrim, H. (2013) · Epilepsia · doi:10.1111/epi.12120 · Cited by 230 · see citing works
Deep Brain Stimulation in Epilepsy
Loddenkemper, T., Pan, A., Neme-Mercante, S., Baker, K. B., Rezai, A. R., Dinner, D. S., Montgomery, E. B., & Lüders, H. O. (2001) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-200111000-00002 · Cited by 217 · see citing works
Self-citationUsability of four commercially-oriented EEG systems
Hairston, W. D., Whitaker, K. W., Ries, A. J., Vettel, J. M., Bradford, J. C., Kerick, S. E., & McDowell, K. (2014) · Journal of Neural Engineering · doi:10.1088/1741-2560/11/4/046018 · Cited by 216 · see citing works
Boon, P., Vonck, K. E. J., van Rijckevorsel, K., Tahry, R. E., Elger, C. E., Mullatti, N., Schulze‐Bonhage, A., Wagner, L., Diehl, B., Hamer, H. M., et al. (2015) · Seizure · doi:10.1016/j.seizure.2015.08.011 · Cited by 202 · see citing works
Detection of seizure-like movements using a wrist accelerometer
Lockman, J., Fisher, R. S., & Olson, D. M. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2011.01.019 · Cited by 195 · see citing works
Prevalence of Epilepsy in Adults in Northern Sweden
Forsgren, L. (1992) · Epilepsia · doi:10.1111/j.1528-1157.1992.tb01690.x · Cited by 184 · see citing works
Deep Brain Stimulation for Epilepsy
Koch, P., & Baltuch, G. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805353-9.00083-8 · Cited by 181 · see citing works
Epilepsy and risk of death and sudden unexpected death in the young: A nationwide study
Holst, A. G., Winkel, B. G., Risgaard, B., et al. (2013) · Epilepsia · doi:10.1111/epi.12328 · Cited by 158 · see citing works
Functional MRI of the pre-ictal state
Federico, P., Abbott, D. F., Briellmann, R. S., Harvey, A. S., & Jackson, G. D. (2005) · Brain · doi:10.1093/brain/awh533 · Cited by 158 · see citing works
Views of patients with epilepsy on seizure prediction devices
Schulze‐Bonhage, A., Sales, F., Wagner, K., Teotónio, R., Carius, A., Schelle, A., & Ihle, M. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.05.008 · Cited by 155 · see citing works
The role of hypoventilation in a sheep model of epileptic sudden death
Johnston, S. C., Horn, J., Valente, J. F., et al. (1995) · Annals of Neurology · doi:10.1002/ana.410370416 · Cited by 154 · see citing works
Bateman, L. M., Spitz, M. C., & Seyal, M. (2010) · Epilepsia · doi:10.1111/j.1528-1167.2009.02513.x · Cited by 151 · see citing works
Prevalence and characteristics of epilepsy in children in Northern Sweden
Sidenvall, R., Forsgren, L., & Heijbel, J. (1996) · Seizure · doi:10.1016/s1059-1311(96)80108-7 · Cited by 149 · see citing works
Continuous monitoring of electrodermal activity during epileptic seizures using a wearable sensor
Poh, M., Loddenkemper, T., Swenson, N. C., Goyal, S., Madsen, J. R., & Picard, R. W. (2010) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2010.5625988 · Cited by 142 · see citing works
Self-citationNijsen, T. M. E., Arends, J. B. A. M., Griep, P. A. M., & Cluitmans, P. J. M. (2005) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.04.011 · Cited by 139 · see citing works
Teixeira, C., Direito, B., Bandarabadi, M., Quyen, M. L. V., Valderrama, M. A., Schelter, B. O., Schulze‐Bonhage, A., Navarro, V., Sales, F., & Dourado, A. (2014) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2014.02.007 · Cited by 132 · see citing works
New horizons in ambulatory electroencephalography
Waterhouse, E. J. (2003) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2003.1213629 · Cited by 129 · see citing works
Velasco, M., Velasco, F., & Velasco, A. L. (2001) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-200111000-00001 · Cited by 127 · see citing works
A Novel Portable Seizure Detection Alarm System: Preliminary Results
Kramer, U., Kipervasser, S., Shlitner, A., & Kuzniecky, R. (2011) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0b013e3182051320 · Cited by 122 · see citing works
Roche‐Labarbe, N., Zaaimi, B., Berquin, P. C., et al. (2008) · Epilepsia · doi:10.1111/j.1528-1167.2008.01711.x · Cited by 118 · see citing works
A model of heart rate changes to detect seizures in severe epilepsy
van Elmpt, W., Nijsen, T. M. E., Griep, P. A. M., & Arends, J. B. A. M. (2006) · Seizure · doi:10.1016/j.seizure.2006.03.005 · Cited by 117 · see citing works
Novel techniques for automated seizure registration: Patients' wants and needs
Hoppe, C., Feldmann, M., Blachut, B., Surges, R., Elger, C. E., & Helmstaedter, C. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.08.006 · Cited by 116 · see citing works
When do patients forget their seizures? An electroclinical study
Kerling, F., Mueller, S., Pauli, E., & Stefan, H. (2006) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2006.05.010 · Cited by 115 · see citing works
Sarkis, R. A., Thomé-Souza, S., Poh, M., Llewellyn, N., Klehm, J., Madsen, J. R., Picard, R. W., Pennell, P. B., Dworetzky, B. A., Loddenkemper, T., et al. (2015) · Epilepsy Research · doi:10.1016/j.eplepsyres.2015.06.005 · Cited by 110 · see citing works
Self-citationParvez, M. Z., & Paul, M. (2015) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2015.2458982 · Cited by 110 · see citing works
Jeppesen, J., Beniczky, S., Johansen, P., Sidenius, P., & Fuglsang‐Frederiksen, A. (2014) · Seizure · doi:10.1016/j.seizure.2014.11.004 · Cited by 101 · see citing works
Seizure-alert dogs: a review and preliminary study
Dalziel, D. J., Uthman, B. M., McGorray, S. P., et al. (2003) · Seizure · doi:10.1016/s105913110200225x · Cited by 99 · see citing works
Conradsen, I., Beniczky, S., Hoppe, K., Wolf, P. S., & Sørensen, H. B. D. (2011) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2011.2178094 · Cited by 96 · see citing works
Szabó, C. Á., Morgan, L. C., Karkar, K. M., Leary, L., Lie, O. V., Girouard, M., & Cavazos, J. E. (2015) · Epilepsia · doi:10.1111/epi.13083 · Cited by 94 · see citing works
Nickels, K. C., Grossardt, B. R., & Wirrell, E. C. (2012) · Epilepsia · doi:10.1111/j.1528-1167.2012.03661.x · Cited by 92 · see citing works
Milošević, M., de Vel, A. V., Bonroy, B., Ceulemans, B., Lagae, L. G., Vanrumste, B., & Huffel, S. V. (2015) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2015.2462079 · Cited by 90 · see citing works
Shoeb, A. H., Pang, T. D., Guttag, J. V., & Schachter, S. C. (2009) · International Journal of Neural Systems · doi:10.1142/s0129065709001938 · Cited by 88 · see citing works
Time-Frequency Analysis of Accelerometry Data for Detection of Myoclonic Seizures
Nijsen, T. M. E., Aarts, R. M., Cluitmans, P. J. M., & Griep, P. A. M. (2010) · IEEE Transactions on Information Technology in Biomedicine · doi:10.1109/titb.2010.2058123 · Cited by 85 · see citing works
Measurement of neural signals from inexpensive, wireless and dry EEG systems
Grummett, T. S., Leibbrandt, R. E., Lewis, T. W., DeLosAngeles, D., Powers, D. M. W., Willoughby, J. O., Pope, K. J., & Fitzgibbon, S. P. (2015) · Physiological Measurement · doi:10.1088/0967-3334/36/7/1469 · Cited by 84 · see citing works
Miniaturized wireless ECG monitor for real-time detection of epileptic seizures
Massé, F., van Bussel, M., Serteyn, A., Arends, J. B. A. M., & Penders, J. (2013) · ACM Transactions on Embedded Computing Systems · doi:10.1145/2485984.2485990 · Cited by 80 · see citing works
Extracting and Selecting Distinctive EEG Features for Efficient Epileptic Seizure Prediction
Wang, N., & Lyu, M. R.-T. (2014) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2014.2358640 · Cited by 80 · see citing works
Temporal trends in the mortality of people with epilepsy: A review
Neligan, A., Bell, G. S., Shorvon, S. D., & Sander, J. W. A. S. (2010) · Epilepsia · doi:10.1111/j.1528-1167.2010.02711.x · Cited by 78 · see citing works
SUDEP and other causes of mortality in childhood-onset epilepsy
Sillanpää, M. L., & Shinnar, S. (2013) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.04.016 · Cited by 78 · see citing works
On the proper selection of preictal period for seizure prediction
Bandarabadi, M., Rasekhi, J., Teixeira, C., Karami, M. R., & Dourado, A. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.03.010 · Cited by 76 · see citing works
Vision-based motion detection, analysis and recognition of epileptic seizures—A systematic review
Pediaditis, M., Tsiknakis, M., & Leitgeb, N. (2012) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2012.08.005 · Cited by 76 · see citing works
Patterson, A. L., Mudigoudar, B. D., Fulton, S. P., McGregor, A., Poppel, K. V., Wheless, M. C., Brooks, L., & Wheless, J. W. (2015) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2015.07.002 · Cited by 71 · see citing works
Introduction to the Special Issue on Modeling and Verification of Discrete Event Systems
Khalgui, M. S., & Li, Z. (2013) · ACM Transactions on Embedded Computing Systems · doi:10.1145/2406336.2406337 · Cited by 71 · see citing works
Automatic Segmentation of Episodes Containing Epileptic Clonic Seizures in Video Sequences
Kalitzin, S., Petkov, G. H., Velis, D. N., et al. (2012) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2012.2215609 · Cited by 68 · see citing works
Effect of trained Seizure Alert Dogs on frequency of tonic–clonic seizures
Strong, V., Brown, S., Huyton, M., & Coyle, H. (2002) · Seizure · doi:10.1053/seiz.2001.0656 · Cited by 67 · see citing works
Patterns of muscle activation during generalized tonic and tonic-clonic epileptic seizures
Conradsen, I., Wolf, P., Sams, T., Sørensen, H. B. D., & Beniczky, S. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2011.03286.x · Cited by 66 · see citing works
Prospective Study of the Emfit Movement Monitor
Poppel, K. V., Fulton, S. P., McGregor, A., et al. (2013) · Journal of Child Neurology · doi:10.1177/0883073812471858 · Cited by 65 · see citing works
Development of a Body Sensor Network to Detect Motor Patterns of Epileptic Seizures
Dalton, A. F., Patel, S., Chowdhury, A. R., Welsh, M., Pang, T., Schachter, S. C., OLaighin, G. M., & Bonato, P. (2012) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2012.2204990 · Cited by 65 · see citing works
Premature mortality in refractory partial epilepsy: does surgical treatment make a difference?
Bell, G. S., Sinha, S., de Tisi, J., et al. (2010) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2008.170837 · Cited by 65 · see citing works
Detecting nocturnal convulsions: Efficacy of the MP5 monitor
Carlson, C., Arnedo, V., Cahill, M., & Devinsky, O. (2008) · Seizure · doi:10.1016/j.seizure.2008.08.007 · Cited by 63 · see citing works
Forecasting epilepsy from the heart rate signal
Kerem, D. H., & Geva, A. B. (2005) · Medical & Biological Engineering & Computing · doi:10.1007/bf02345960 · Cited by 63 · see citing works
Peri-ictal ECG changes in childhood epilepsy: Implications for detection systems
Jansen, K., Varon, C., Huffel, S. V., & Lagae, L. G. (2013) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.06.030 · Cited by 62 · see citing works
Seizure-alert dogs — fact or fiction?
Strong, V., Brown, S., & Walker, R. L. (1999) · Seizure · doi:10.1053/seiz.1998.0250 · Cited by 61 · see citing works
Seizure-alerting and -response behaviors in dogs living with epileptic children
Kirton, A., Wirrell, E. C., Zhang, J., et al. (2004) · Neurology · doi:10.1212/wnl.62.12.2303 · Cited by 61 · see citing works
AUTOMATED SEIZURE DETECTION USING EKG
Osorio, I. (2013) · International Journal of Neural Systems · doi:10.1142/s0129065714500014 · Cited by 60 · see citing works
Evaluation of novel algorithm embedded in a wearable sEMG device for seizure detection
Conradsen, I., Beniczky, S., Wolf, P. S., Jennum, P., & Sørensen, H. B. D. (2012) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2012.6346361 · Cited by 57 · see citing works
Long-term Surface Cortical Cerebral Blood Flow Monitoring in Temporal Lobe Epilepsy
Weinand, M. E., Carter, L. P., Patton, D. D., et al. (1994) · Neurosurgery · doi:10.1227/00006123-199410000-00011 · Cited by 57 · see citing works
Long-term home monitoring of hypermotor seizures by patient-worn accelerometers
de Vel, A. V., Cuppens, K., Bonroy, B., Milošević, M., Huffel, S. V., Vanrumste, B., Lagae, L., & Ceulemans, B. (2012) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2012.10.006 · Cited by 56 · see citing works
Quantifying Limb Movements in Epileptic Seizures Through Color-Based Video Analysis
Lu, H., Pan, Y., Mandal, B., Eng, H., Guan, C., & Chan, D. W. S. (2012) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2012.2228649 · Cited by 54 · see citing works
Behbahani, S., Dabanloo, N. J., Nasrabadi, A. M., Teixeira, C., & Dourado, A. (2013) · The Anatolian Journal of Cardiology · doi:10.5152/akd.2013.237 · Cited by 53 · see citing works
Conradsen, I., Beniczky, S., Wolf, P., Kjær, T. W., Sams, T., & Sørensen, H. B. D. (2011) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2011.06.005 · Cited by 50 · see citing works
Schulc, E., Unterberger, I., Saboor, S., Hilbe, J., Ertl, M., Ammenwerth, E., Trinka, E., & Them, C. (2011) · Epilepsy Research · doi:10.1016/j.eplepsyres.2011.02.010 · Cited by 50 · see citing works
Robust beat detector for ambulatory cardiac monitoring
Romero, I., Grundlehner, B., & Penders, J. (2009) · doi:10.1109/iembs.2009.5334543 · Cited by 50 · see citing works
Cardiopulmonary complications during pediatric seizures: A prelude to understanding SUDEP
Singh, K., Katz, E. S., Żarowski, M., et al. (2013) · Epilepsia · doi:10.1111/epi.12153 · Cited by 48 · see citing works
A Magnetometer-Based Approach for Studying Human Movements
Bonnet, S., & Héliot, R. (2007) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2007.890742 · Cited by 48 · see citing works
Prospective Study of 2 Bed Alarms for Detection of Nocturnal Seizures
Fulton, S. P., Poppel, K. V., McGregor, A., Ellis, M., Patters, A. B., & Wheless, J. W. (2012) · Journal of Child Neurology · doi:10.1177/0883073812462064 · Cited by 47 · see citing works
Can seizure-alert dogs predict seizures?
Brown, S., & Goldstein, L. H. (2011) · Epilepsy Research · doi:10.1016/j.eplepsyres.2011.10.019 · Cited by 46 · see citing works
Jeppesen, J., Beniczky, S., Johansen, P., Sidenius, P., & Fuglsang‐Frederiksen, A. (2015) · Seizure · doi:10.1016/j.seizure.2015.01.015 · Cited by 45 · see citing works
Validation of a wireless dry electrode system for electroencephalography
Wyckoff, S. N., Sherlin, L. H., Ford, N. L., & Dalke, D. (2015) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-015-0089-2 · Cited by 44 · see citing works
Using spatio-temporal interest points (STIP) for myoclonic jerk detection in nocturnal video
Cuppens, K., Chen, C., Wong, K. B.-Y., de Vel, A. V., Lagae, L., Ceulemans, B., Tuytelaars, T., Huffel, S. V., Vanrumste, B., & Aghajan, H. K. (2012) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2012.6346955 · Cited by 44 · see citing works
O’Dwyer, R., Cunha, J. P. S., Vollmar, C., et al. (2007) · Epilepsia · doi:10.1111/j.1528-1167.2006.00967.x · Cited by 42 · see citing works
Detection of tonic epileptic seizures based on surface electromyography
Larsen, S. N., Conradsen, I., Beniczky, S., & Sørensen, H. B. D. (2014) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2014.6943747 · Cited by 42 · see citing works
Diagnostic accuracy of microEEG: A miniature, wireless EEG device
Grant, A. C., Abdel-Baki, S. G., Omurtag, A., Sinert, R. H., Chari, G., Malhotra, S., Weedon, J., Fenton, A. A., & Zehtabchi, S. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.03.015 · Cited by 41 · see citing works
Detecting rare events using extreme value statistics applied to epileptic convulsions in children
Luca, S., Karsmakers, P., Cuppens, K., Croonenborghs, T., de Vel, A. V., Ceulemans, B., Lagae, L., Huffel, S. V., & Vanrumste, B. (2013) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2013.11.007 · Cited by 41 · see citing works
Patient Specific Seizure Prediction System Using Hilbert Spectrum and Bayesian Networks Classifiers
Özdemir, N., & Yıldırım, E. (2014) · Computational and Mathematical Methods in Medicine · doi:10.1155/2014/572082 · Cited by 39 · see citing works
Using photoplethysmography in heart rate monitoring of patients with epilepsy
van Andel, J., Ungureanu, C., Aarts, R., Leijten, F., & Arends, J. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.02.018 · Cited by 39 · see citing works
Frontal hemodynamic changes precede EEG onset of temporal lobe seizures
Seyal, M. (2013) · Clinical Neurophysiology · doi:10.1016/j.clinph.2013.09.003 · Cited by 37 · see citing works
Generic single-channel detection of absence seizures
Petersen, E. B., Duun‐Henriksen, J., Mazzaretto, A., Kjær, T. W., Thomsen, C. E., & Sørensen, H. B. D. (2011) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2011.6091194 · Cited by 36 · see citing works
Long-term mortality in children and young adults with epilepsy—A population-based cohort study
Christensen, J., Pedersen, C. B., Sidenius, P., Olsen, J., & Vestergaard, M. (2015) · Epilepsy Research · doi:10.1016/j.eplepsyres.2015.05.001 · Cited by 36 · see citing works
“Seizure-alert dogs”: Observations from an inpatient video/EEG unit
ortiz, R. V., & Liporace, J. D. (2005) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.02.012 · Cited by 34 · see citing works
Conradsen, I., Beniczky, S., Wolf, P. S., Henriksen, J. H., Sams, T., & Sørensen, H. B. D. (2010) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2010.5627218 · Cited by 34 · see citing works
Quantitative movement analysis differentiates focal seizures characterized by automatisms
Rémi, J., Cunha, J. P. S., Vollmar, C., et al. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2011.01.020 · Cited by 33 · see citing works
Automatic Detection of Childhood Absence Epilepsy Seizures: Toward a Monitoring Device
Duun‐Henriksen, J., Madsen, R. E., Remvig, L. S., et al. (2012) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2012.02.018 · Cited by 33 · see citing works
de Vel, A. V., Verhaert, K., & Ceulemans, B. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.06.014 · Cited by 32 · see citing works
Detection system of motor epileptic seizures through motion analysis with 3D accelerometers
Jallon, P., Bonnet, S., Antonakios, M., et al. (2009) · doi:10.1109/iembs.2009.5334770 · Cited by 32 · see citing works
Gadhoumi, K., Gotman, J., & Lina, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121182 · Cited by 29 · see citing works
Is elevated pre-ictal heart rate associated with secondary generalization in partial epilepsy?
Nilsen, K. B., Haram, M., Tangedal, S., Sand, T., & Brodtkorb, E. (2010) · Seizure · doi:10.1016/j.seizure.2010.03.003 · Cited by 29 · see citing works
Conradsen, I., Beniczky, S., Wolf, P., et al. (2009) · doi:10.1109/iembs.2009.5335334 · Cited by 28 · see citing works
Diurnal changes of blood pressure, heart rate and body temperature during sleep in the rat
Séi, H., FURUNO, N., & Morita, Y. (1997) · Journal of Sleep Research · doi:10.1046/j.1365-2869.1997.00038.x · Cited by 27 · see citing works
Ictal head turning in frontal and temporal lobe epilepsy
Rémi, J., Wagner, P., O’Dwyer, R., et al. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2011.03076.x · Cited by 26 · see citing works
Valle, B. G. D., Cash, S. S., & Sodini, C. G. (2014) · doi:10.1109/embc.2014.6944984 · Cited by 25 · see citing works
Becq, G., Kahane, P., Minotti, L., et al. (2013) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2013.2244597 · Cited by 25 · see citing works
Jakab, A., Kulkas, A., Salpavaara, T., et al. (2014) · BioMedical Engineering OnLine · doi:10.1186/1475-925x-13-60 · Cited by 25 · see citing works
Is seizure detection based on EKG clinically relevant?
Osorio, I., & Manly, B. F. J. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.01.026 · Cited by 24 · see citing works
Wag the dog: Skepticism on seizure alert canines
Doherty, M. J., & Haltiner, A. M. (2007) · Neurology · doi:10.1212/01.wnl.0000252369.82956.a3 · Cited by 23 · see citing works
Impact of Patient-Specificity on Seizure Onset Detection Performance
Shoeb, A. H., Bourgeois, B. F. D., Treves, S. T., Schachter, S. C., & Guttag, J. V. (2007) · Conference proceedings · doi:10.1109/iembs.2007.4353240 · Cited by 22 · see citing works
Krauss, G. L., Choi, J. S., & Lesser, R. P. (2007) · Neurology · doi:10.1212/01.wnl.0000250345.23677.6b · Cited by 22 · see citing works
Non-intrusive head movement analysis of videotaped seizures of epileptic origin
Mandal, B., Eng, H., Lu, H., et al. (2012) · doi:10.1109/embc.2012.6347376 · Cited by 21 · see citing works
Collection and Exploratory Analysis of Attitude Sensor Data in an Epilepsy Monitoring Unit
Becq, G., Bonnet, S., Minotti, L., et al. (2007) · Conference proceedings · doi:10.1109/iembs.2007.4352904 · Cited by 19 · see citing works
Seizure prediction using adaptive neuro-fuzzy inference system
Rabbi, A. F., Azinfar, L., & Fazel-Rezai, R. (2013) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2013.6609947 · Cited by 18 · see citing works
Epileptic seizure detection - an AR model based algorithm for implantable device
Kim, H., & Rosén, J. (2010) · Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society · doi:10.1109/iembs.2010.5626784 · Cited by 17 · see citing works
A feasibility study on a single-unit wireless EEG sensor
Luan, B., Jia, W., Thirumala, P. D., et al. (2014) · doi:10.1109/icosp.2014.7015401 · Cited by 14 · see citing works
Model for arm movements during myoclonic seizures
Nijsen, T. M. E., Aarts, R. M., Arends, J. B. A. M., & Cluitmans, P. J. M. (2007) · Conference proceedings · doi:10.1109/iembs.2007.4352607 · Cited by 13 · see citing works
Electrical stimulation and gene-based neuromodulation for control of medically-refractory epilepsy
Alexopoulos, A. V., Gonugunta, V., Yang, J., et al. (2007) · Springer eBooks · doi:10.1007/978-3-211-33081-4_33 · Cited by 11 · see citing works
A simulation study on a single-unit wireless EEG Sensor
Luan, B., & Sun, M. (2015) · Annual Northeast Biomedical Engineering Conference · doi:10.1109/nebec.2015.7117176 · Cited by 9 · see citing works
Increased cerebral oxygenation precedes generalized tonic clonic seizures
Moseley, B. D., Britton, J. W., & So, E. L. (2014) · Epilepsy Research · doi:10.1016/j.eplepsyres.2014.09.017 · Cited by 9 · see citing works
Seizure prediction in intracranial EEG: A patient-specific rule-based approach
Aarabi, A., & He, B. (2011) · doi:10.1109/iembs.2011.6090709 · Cited by 8 · see citing works
Epileptic seizure prediction using variational mixture of Gaussians
Zandi, A. S., Dumont, G. A., Javidan, M., et al. (2011) · doi:10.1109/iembs.2011.6091861 · Cited by 5 · see citing works
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Research works printed but not linked: 1
- Hoppe C, Poepel A, Elger CE. Epilepsy: accuracy of patient seizure counts. Arch Neurol 2007;64(11):1595-9.
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Artificial intelligence for clinical trial design
Harrer, S., Shah, P., Antony, B., & Hu, J. (2019) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2019.05.005 · Cited by 672 · see citing works
Diagnostic challenges in epilepsy: seizure under-reporting and seizure detection
Elger, C. E., & Hoppe, C. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30038-3 · Cited by 403 · see citing works
Multicenter clinical assessment of improved wearable multimodal convulsive seizure detectors
Onorati, F., Regalia, G., Caborni, C., Migliorini, M., Bender, D., Poh, M., Frazier, C., Kovitch Thropp, E., Mynatt, E. D., Bidwell, J., et al. (2017) · Epilepsia · doi:10.1111/epi.13899 · Cited by 212 · see citing works
Self-citationSeizure detection using wearable sensors and machine learning: Setting a benchmark
Tang, J., El Atrache, R., Yu, S., Asif, U., Jackson, M., Roy, S., Mirmomeni, M., Cantley, S., Sheehan, T., Schubach, S., et al. (2021) · Epilepsia · doi:10.1111/epi.16967 · Cited by 146 · see citing works
Self-citationData quality evaluation in wearable monitoring
Böttcher, S., Vieluf, S., Bruno, E., Joseph, B., Epitashvili, N., Biondi, A., Zabler, N., Glasstetter, M., Dümpelmann, M., Van Laerhoven, K., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-25949-x · Cited by 91 · see citing works
Self-citationNon-invasive wearable seizure detection using long–short-term memory networks with transfer learning
Nasseri, M., Pal Attia, T., Joseph, B., Gregg, N. M., Nurse, E. S., Viana, P. F., Schulze-Bonhage, A., Dümpelmann, M., Worrell, G., Freestone, D. R., et al. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/abef8a · Cited by 66 · see citing works
Robust Epileptic Seizure Detection on Wearable Systems with Reduced False-Alarm Rate
Zanetti, R., Aminifar, A., & Atienza, D. (2020) · 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) · doi:10.1109/embc44109.2020.9175339 · Cited by 45 · see citing works
Böttcher, S., Bruno, E., Epitashvili, N., Dümpelmann, M., Zabler, N., Glasstetter, M., Ticcinelli, V., Thorpe, S., Lees, S., Van Laerhoven, K., et al. (2022) · Sensors · doi:10.3390/s22093318 · Cited by 23 · see citing works
Glasstetter, M., Böttcher, S., Zabler, N., Epitashvili, N., Dümpelmann, M., Richardson, M. P., & Schulze-Bonhage, A. (2021) · Sensors · doi:10.3390/s21186017 · Cited by 21 · see citing works
El Atrache, R., Tamilia, E., Mohammadpour Touserkani, F., Hammond, S., Papadelis, C., Kapur, K., Jackson, M., Bucciarelli, B., Tsuboyama, M., Sarkis, R. A., et al. (2020) · Epilepsia · doi:10.1111/epi.16621 · Cited by 16 · see citing works
Self-citation
- Authors
- Ulate-Campos, A., Coughlin, F., Gaínza-Lein, M., Fernández, I. S., Pearl, P. L., & Loddenkemper, T.
- Affiliations
- Hospital Nacional de Niños (CR)
- Boston Children's Hospital (US)
- Corresponding author
- Ulate-Campos, A.
- Coughlin, F.
- Fernández, I. Sánchez
- Pearl, P.L.
- Loddenkemper, T.
- Venue
- Seizure
- Publisher
- Elsevier BV
- Published
- 2016-08
- Volume
- 40
- Pages
- 88-101
- ISSN
- 1059-1311 (ISSN-L)
- OpenAlex
- W2422080706
- Cited by
- 233
- References
- 140
- Citations by year
- 2026: 6 · 2025: 20 · 2024: 20 · 2023: 29 · 2022: 23 · 2021: 37 · 2020: 29 · 2019: 26 · 2018: 32 · 2017: 8 · 2016: 3
- FWCI
- 3.28
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Seizure (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Epilepsy Research Fund
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
- Physical Sciences › Computer Science › Artificial Intelligence › Seismology and Earthquake Studies
- Keywords
- epilepsy, drug-resistant epilepsy, seizure types, closed-loop systems, device selection, device validation, seizure semiology
- MeSH terms
- Humans, Seizures, Neurophysiological Monitoring
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