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Cited by 419

The DOI matches its Crossref record; 103 of the 103 references it cites were found in a registry or an index.

Progress towards therapies for disease modification in Parkinson's disease

Open access
Vijiaratnam, Nirosen, Simuni, Tanya, Bandmann, Oliver, Morris, Huw R, Foltynie, Thomas·2021·The Lancet Neurology

Abstract

The development of interventions to slow or halt the progression of Parkinson's disease remains a priority for patients and researchers alike. To date, no agents have been shown to have unequivocal evidence of disease-modifying effects in Parkinson's disease. The absence of disease-modifying treatments might relate not only to inadequate approaches for the selection of therapeutic candidates but also to insufficient attention to detail in clinical trial design. Better understanding of Parkinson's disease pathogenesis associated with advances in laboratory models, the use of objective biomarkers of disease progression and target engagement, and a focus on agents known to be safe for human use, alongside the use of precision medicine approaches, should together greatly increase the likelihood for successful identification of disease-modifying treatments for Parkinson's disease.

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Crossref · 10.1016/s1474-4422(21)00061-2

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Metadata

Authors
Vijiaratnam, N., Simuni, T., Bandmann, O., Morris, H. R., & Foltynie, T.
Venue
The Lancet Neurology
Publisher
Elsevier BV
Published
2021-07
Volume
20
Issue
7
Pages
559-572
ISSN
1474-4422 (ISSN-L)
OpenAlex
W3172058623
Cited by
419
References
103
FWCI
21.64
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Progress towards therapies for disease modification in Parkinson's disease. https://app.cochat.ai/papers/10.1016/s1474-4422(21)00061-2
The paper
Vijiaratnam, N., Simuni, T., Bandmann, O., Morris, H. R., & Foltynie, T. (2021). Progress towards therapies for disease modification in Parkinson's disease. The Lancet Neurology. https://doi.org/10.1016/s1474-4422(21)00061-2

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.