Cited by 963Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolismIron Metabolism and Disorders

Increased nigral iron content in postmortem parkinsonian brain

Dexter, D.T., Wells, F.R., Agid, F., Agid, Y., Lees, A.J., Jenner, P., Marsden, C.D.·1987·The Lancet

Integrity signals

Registry

Crossref · 10.1016/s0140-6736(87)91361-4

Cites

7 of 7 references verified0 citation errors · 0 not checkable

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Claims the paper makes

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Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Several studies have shown increases of total iron concentration in the substantia nigra of patients with Parkinson's disease.

    “Several studies have shown increases of total iron concentration in the substantia nigra of patients with Parkinson’s disease.”
  • Neuropathological studies using accurate spectroscopic methods showed that iron concentrations in the substantia nigra pars compacta and reticulata increase with disease severity.

    “Neuropathological studies that used accurate spectroscopic methods to measure total iron concentrations in specific brain regions, such as substantia nigra pars compacta and reticulata showed that iron concentrations in these regions increase with disease severity.100–103”

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Authors
Dexter, D. T., Wells, F. R., Agid, F., Agid, Y., Lees, A. J., Jenner, P., & Marsden, C. D.
Venue
The Lancet
Publisher
Elsevier BV
Published
1987-11
Volume
330
Issue
8569
Pages
1219-1220
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2039403847
Cited by
963
References
7
Citations by year
2026: 11 · 2025: 15 · 2024: 17 · 2023: 19 · 2022: 28 · 2021: 28 · 2020: 31 · 2019: 35 · 2018: 22 · 2017: 32 · 2016: 25 · 2015: 44 · 2014: 28 · 2013: 27 · 2012: 18
FWCI
26.62
Type
journal article
Language
en
Open access
closed
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Topics
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
  • Life Sciences › Neuroscience › Neurology › Neurological diseases and metabolism
  • Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
Keywords
substantia nigra, iron content, Parkinson's disease, postmortem brain, iron accumulation
MeSH terms
Aged, Humans, Iron, Parkinson Disease, Substantia Nigra

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