A molecular explanation of interactions between photic and non-photic circadian clock-resetting stimuli
Abstract
Non-photic clock-resetting events (arousal and locomotor activity) in the subjective day reduced expression of Period genes in the suprachiasmatic nucleus of hamsters. This decrease was attenuated by a 30-min light pulse occurring during the last 0.5 h of 3.5 h of confinement to a novel running wheel. This provides an example at the molecular level of an interaction between different modalities of synchronizing agents.
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Many physiological systems that are regulated by circadian rhythms are also known to influence circadian function.
“In support of this theory, many physiological systems that are regulated by circadian rhythms are also known to influence circadian function.”
From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [111]
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- Authors
- Maywood, E. S., & Mrosovsky, N.
- Affiliations
- University of Cambridge (GB)
- University of Toronto (CA)
- Corresponding author
- Mrosovsky, N.
- ORCID
- Maywood, E.S.
- Venue
- Gene Expression Patterns
- Publisher
- Elsevier BV
- Published
- 2001-08
- Volume
- 1
- Issue
- 1
- Pages
- 27-31
- ISSN
- 1567-133X (ISSN-L)
- OpenAlex
- W2034725606
- Cited by
- 70
- References
- 21
- Citations by year
- 2025: 4 · 2024: 1 · 2023: 3 · 2021: 1 · 2020: 1 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 2 · 2012: 3
- FWCI
- 1.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Gene Expression Patterns (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Keywords
- circadian clock, non-photic entrainment, light entrainment, period gene, suprachiasmatic nucleus, arousal, locomotor activity, running wheel, light pulses, hamster, clock gene expression
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