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Clinical and Therapeutic Profile and Quality of Life of Patients With Seborrheic Dermatitis
Open accessAbstract
The clinical characteristics of seborrheic dermatitis (SD), therapeutic strategies employed in current clinical practice and impact on the quality of life in the Spanish population are described. An epidemiological, multicenter, transversal study in patients older than 16 years with seborrheic dermatitis. We evaluated the intensity of symptoms (scale 0-4), and impact on the quality of life by the Skindex-29 questionnaire (scale 0-100). Two thousand one hundred and fifty nine patients participated, the mean age was 43.6 years, 55% were men and 42% had a family history of seborrheic dermatitis. Diagnosis is usually carried out at a mean age of 33.7 years. The median number of outbreaks in the last year is three. The median duration of each outbreak is 14 days. The most involved areas are the face (88%) and scalp (70%). The mean intensities are as follows: scaling 1.9, erythema 1.89, pruritus 1.73, oily skin 1.52, and induration 0.87. Ninety-eight percent of patients report a trigger factor for outbreaks, namely stress/depression/fatigue (76%) and seasonal variation (44%). Acne is the most common concomitant disease (35%). The most common treatments are topical steroids (60%), imidazole antifungals (35%) and hydratating/nutritive products (31%). The mean Skindex-29 global score is 20.5. The most common clinical profile of seborrheic dermatitis is a 40-year-old patient with facial/scalp involvement of mild to moderate intensity with a history of stress/depression/fatigue prior to the outbreak. The most common treatments in the daily clinical practice are topical steroids and imidazole antifungals. The impact of seborrheic dermatitis in the quality of life is low. Se describen las características clínicas de la dermatitis seborreica (DS), las estrategias terapéuticas empleadas en la práctica clínica habitual y el impacto en la calidad de vida de la población afectada en España. Estudio epidemiológico, multicéntrico, transversal en pacientes mayores de 16 años con DS. Se evaluaron la intensidad de los síntomas (escala 0-4) y el impacto en la calidad de vida mediante el cuestionario Skindex-29 (escala 0-100). Participaron 2.159 pacientes, con una edad media de 43,6 años, el 55% hombres y el 42% con antecedentes familiares de DS. El diagnóstico se realizó como media a los 33,7 años. La mediana de brotes en el último año es de 3. La duración mediana de cada brote es de 14 días. Las zonas más afectadas son la facial (88%) y el cuero cabelludo (70%). Las medias de las intensidades son: descamación 1,9, eritema 1,89, prurito 1,73, piel grasa 1,52, infiltración 0,87. El 98% de los pacientes refiere un factor desencadenante de los brotes, estrés/depresión/fatiga (76%) y estacionalidad (44%). La patología concomitante más común es el acné (35%). Los tratamientos más frecuentes son corticoides tópicos (60%), antimicóticos imidazólicos (35%) e hidratantes/nutritivos (31%). La puntuación global media del Skindex-29 es de 20,5. El perfil clínico mayoritario de la DS es un paciente de 40 años, con afectación facial/cuero cabelludo, intensidad leve-moderada, padeciendo un episodio de estrés/depresión/fatiga previo al brote. Los tratamientos más frecuentes, en la práctica clínica habitual, son corticoides tópicos y antimicóticos imidazólicos. El impacto de la DS sobre la calidad de vida es bajo.
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“SD can affect the scalp as well as other seborrheic areas, and involves itchy and flaking or scaling skin, inflammation and pruritus.”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [29]
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“On the other hand, in adults, SD is a chronic or relapsing condition, featured by erythematous patches, with flaky, large, oily or dry scales in sebum-rich areas such as face (87.7%), scalp (70.3%), upper trunk (26.8%), lower extremities (2.3%), and upper extremities (1.3%) [5,7,29].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [29]
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Chren, M.-M., Lasek, R. J., Quinn, L. M., Mostow, E. N., & Zyzanski, S. J. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12365600 · Cited by 699
Which chronic conditions are associated with better or poorer quality of life?
Sprangers, M. A. G., de Regt, E. B., Andries, F., van Agt, H. M. E., Bijl, R. V., de Boer, J. B., Foets, M., Hoeymans, N., Jacobs, A., Kempen, G. I. J. M., et al. (2000) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00204-3 · Cited by 649
Chren, M.-M. (1997) · Archives of Dermatology · doi:10.1001/archderm.1997.03890470111018 · Cited by 480
Chren, M. (1997) · Archives of Dermatology · doi:10.1001/archderm.133.11.1433 · Cited by 446
Acne Vulgaris and the Quality of Life of Adult Dermatology Patients
Lasek, R. J., & Chren, M.-M. (1998) · Archives of Dermatology · doi:10.1001/archderm.134.4.454 · Cited by 285
Stressful Life Events and Skin Diseases: Disentangling Evidence from Myth
Picardi, A., & Abeni, D. (2001) · Psychotherapy and Psychosomatics · doi:10.1159/000056237 · Cited by 267
(2006) · PubMed · Cited by 178
Gupta, A. K., Bluhm, R., Cooper, E. A., Summerbell, R. C., & Batra, R. (2003) · Dermatologic Clinics · doi:10.1016/s0733-8635(03)00028-7 · Cited by 137
Wiwanitkit, V. (2004) · International Journal of Dermatology · doi:10.1111/j.1365-4632.2004.01649.x · Cited by 87
The Spanish version of Skindex‐29
Jones‐Caballero, M., Fernández‐Peñas, P., García‐Diez, A., Badia, X. C., & Chren, M. (2000) · International Journal of Dermatology · doi:10.1046/j.1365-4362.2000.00944.x · Cited by 78
Research works printed but not linked: 1
- Gupta, 2004, Seborrheic dermatitis, JEADV, 18, 13
Cited by
Seborrheic Dermatitis and Dandruff: A Comprehensive Review
(2015) · Journal of Clinical and Investigative Dermatology · doi:10.13188/2373-1044.1000019 · Cited by 398
Sampaio, A. L. S. B., Mameri, Â. C. A., Vargas, T. J. D. S., Ramos-e-Silva, M., Nunes, A. P., & Carneiro, S. C. D. S. (2011) · Anais Brasileiros de Dermatologia · doi:10.1590/s0365-05962011000600002 · Cited by 103
Metadata
- Authors
- Peyrí, J., & Lleonart, M.
- Affiliations
- Novartis (Spain) (ES)
- Venue
- Actas Dermo-Sifiliográficas (English Edition)
- Publisher
- Elsevier BV
- Published
- 2007
- Volume
- 98
- Issue
- 7
- Pages
- 476-482
- ISSN
- 0001-7310 (ISSN-L)
- 1578-2190
- OpenAlex
- W2068416389
- Cited by
- 68
- References
- 16
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 5 · 2023: 6 · 2022: 6 · 2021: 4 · 2020: 5 · 2019: 3 · 2018: 4 · 2017: 3 · 2016: 5 · 2015: 6 · 2014: 6 · 2013: 4 · 2012: 1
- FWCI
- 0.92
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- creativecommons.org/licenses/by-nc-nd/4.0/ (vor, 4994 d)
- Locations
- Actas Dermo-Sifiliográficas (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Nail Diseases and Treatments
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Cutaneous lymphoproliferative disorders research
- Keywords
- seborrheic dermatitis, quality of life, Skindex-29, topical corticosteroids, imidazole antifungals, pruritus, seasonal variation, scalp involvement, facial involvement, clinical profile, treatment patterns, Spanish patients
- MeSH terms
- Acne Vulgaris, Adolescent, Adult, Cross-Sectional Studies, Dermatologic Agents, Female, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Dermatitis, Seborrheic, Severity of Illness Index, Spain, Stress, Psychological, Comorbidity, Anti-Allergic Agents
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- Peyrí, J., & Lleonart, M. (2007). Clinical and Therapeutic Profile and Quality of Life of Patients With Seborrheic Dermatitis. Actas Dermo-Sifiliográficas (English Edition). https://doi.org/10.1016/s1578-2190(07)70491-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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