The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
Phytochemistry, pharmacology, and therapeutic uses of black seed ( Nigella sativa )
Abstract
Black seed (Nigella sativa) is an annual flowering plant from Ranunculaceae family, native to southwest Asia. This plant has many food and medicinal uses. The use of its seeds and oil is common for treatment of many diseases, including rheumatoid arthritis, asthma, inflammatory diseases, diabetes and digestive diseases. The purpose of this study was to provide a comprehensive review on the scientific reports that have been published about N. sativa. The facts and statistics presented in this review article were gathered from the journals accessible in creditable databases such as Science Direct, Medline, PubMed, Scopus, EBSCO, EMBASE, SID and IranMedex. The keywords searched in Persian and English books on medicinal plants and traditional medicine, as well as the above reputable databases were "Black seed", "Nigella sativa", "therapeutic effect", and "medicinal plant". The results showed that N. sativa has many biological effects such as anti-inflammatory, anti-hyperlipidemic, anti-microbial, anti-cancer, anti-oxidant, anti-diabetic, anti-hypertensive, and wound healing activities. It also has effects on reproductive, digestive, immune and central nervous systems, such as anticonvulsant and analgesic activities. In summary, it can be used as a valuable plant for production of new drugs for treatment of many diseases.
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Cites
Antioxidant activity of Nigella sativa essential oil
Burits, M., & Bucar, F. (2000) · Phytotherapy Research · doi:10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q · Cited by 1,857
A review on therapeutic potential of Nigella sativa: A miracle herb
Ahmad, A., Husain, A., Mujeeb, M., Khan, S. A., Najmi, A. K., Siddique, N. A., Damanhouri, Z. A., & Anwar, F. (2013) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/s2221-1691(13)60075-1 · Cited by 1,430
The role of cyclooxygenases in inflammation, cancer, and development
Williams, C. S., Mann, M., & DuBois, R. N. (1999) · Oncogene · doi:10.1038/sj.onc.1203286 · Cited by 1,417
Pharmacological and toxicological properties of Nigella sativa
Ali, B. H., & Blunden, G. (2003) · Phytotherapy Research · doi:10.1002/ptr.1309 · Cited by 1,119
Immunomodulatory and therapeutic properties of the Nigella sativa L. seed
Salem, M. L. (2005) · International Immunopharmacology · doi:10.1016/j.intimp.2005.06.008 · Cited by 853
Houghton, P., Zarka, R., de las Heras, B., & Hoult, J. (1995) · Planta Medica · doi:10.1055/s-2006-957994 · Cited by 782
The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa
Al-Ghamdi, M. S. (2001) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(01)00216-1 · Cited by 491
Thymoquinone Is a Potent Superoxide Anion Scavenger
Badary, O. A., Taha, R. A., Gamal El-Din, A. M., & Abdel-Wahab, M. H. (2003) · Drug and Chemical Toxicology · doi:10.1081/dct-120020404 · Cited by 447
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Thymoquinone: A promising anti-cancer drug from natural sources
Gali-Muhtasib, H., Roessner, A., & Schneider-Stock, R. (2006) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2005.10.009 · Cited by 420
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Kooti, W., Servatyari, K., Behzadifar, M., Asadi-Samani, M., Sadeghi, F., Nouri, B., & Zare Marzouni, H. (2017) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587217696927 · Cited by 267
Self-citationAnsari, P., Khan, J. T., Choudhary, S., Reberio, A. D., Kumar, S., Seidel, V., Abdel-Wahab, Y. H. A., & Flatt, P. R. (2024) · doi:10.20944/preprints202408.1739.v1 · Cited by 89
Metadata
- Authors
- Kooti, W., Hasanzadeh-Noohi, Z., Sharafi-Ahvazi, N., Asadi-Samani, M., & Ashtary-Larky, D.
- Venue
- Chinese Journal of Natural Medicines
- Publisher
- Elsevier BV
- Published
- 2016-10
- Volume
- 14
- Issue
- 10
- Pages
- 732-745
- ISSN
- 1672-3651 (ISSN-L)
- 1875-5364
- OpenAlex
- W2543104784
- Cited by
- 308
- References
- 77
- FWCI
- 30.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kooti, W., Hasanzadeh-Noohi, Z., Sharafi-Ahvazi, N., Asadi-Samani, M., & Ashtary-Larky, D. (2016). Phytochemistry, pharmacology, and therapeutic uses of black seed ( Nigella sativa ). Chinese Journal of Natural Medicines. https://doi.org/10.1016/s1875-5364(16)30088-7
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