The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Global mortality variations in patients with heart failure: results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study
Open accessAbstract
BACKGROUND: Most data on mortality and prognostic factors in patients with heart failure come from North America and Europe, with little information from other regions. Here, in the International Congestive Heart Failure (INTER-CHF) study, we aimed to measure mortality at 1 year in patients with heart failure in Africa, China, India, the Middle East, southeast Asia and South America; we also explored demographic, clinical, and socioeconomic variables associated with mortality. METHODS: We enrolled consecutive patients with heart failure (3695 [66%] clinic outpatients, 2105 [34%] hospital in patients) from 108 centres in six geographical regions. We recorded baseline demographic and clinical characteristics and followed up patients at 6 months and 1 year from enrolment to record symptoms, medications, and outcomes. Time to death was studied with Cox proportional hazards models adjusted for demographic and clinical variables, medications, socioeconomic variables, and region. We used the explained risk statistic to calculate the relative contribution of each level of adjustment to the risk of death. FINDINGS: We enrolled 5823 patients within 1 year (with 98% follow-up). Overall mortality was 16·5%: highest in Africa (34%) and India (23%), intermediate in southeast Asia (15%), and lowest in China (7%), South America (9%), and the Middle East (9%). Regional differences persisted after multivariable adjustment. Independent predictors of mortality included cardiac variables (New York Heart Association Functional Class III or IV, previous admission for heart failure, and valve disease) and non-cardiac variables (body-mass index, chronic kidney disease, and chronic obstructive pulmonary disease). 46% of mortality risk was explained by multivariable modelling with these variables; however, the remainder was unexplained. INTERPRETATION: Marked regional differences in mortality in patients with heart failure persisted after multivariable adjustment for cardiac and non-cardiac factors. Therefore, variations in mortality between regions could be the result of health-care infrastructure, quality and access, or environmental and genetic factors. Further studies in large, global cohorts are needed. FUNDING: The study was supported by Novartis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.019 · Cited by 12,536
Peduzzi, P., Concato, J., Feinstein, A. R., & Holford, T. R. (1995) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(95)00048-8 · Cited by 2,154
Wang, H., Dwyer-Lindgren, L., Lofgren, K. T., Rajaratnam, J. K., Marcus, J. R., Levin-Rector, A., Levitz, C. E., Lopez, A. D., & Murray, C. J. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61719-x · Cited by 810
Crespo-Leiro, M. G., Anker, S. D., Maggioni, A. P., Coats, A. J., Filippatos, G., Ruschitzka, F., Ferrari, R., Piepoli, M. F., Delgado Jimenez, J. F., Metra, M., et al. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.566 · Cited by 798
Cited by
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Beaton, A. Z., Boehme, A. K., Buxton, A. E., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001123 · Cited by 8,300
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Alonso, A., Beaton, A. Z., Bittencourt, M. S., Boehme, A. K., Buxton, A. E., Carson, A. P., Commodore-Mensah, Y., et al. (2022) · Circulation · doi:10.1161/cir.0000000000001052 · Cited by 5,987
Groenewegen, A., Rutten, F. H., Mosterd, A., & Hoes, A. W. (2020) · European Journal of Heart Failure · doi:10.1002/ejhf.1858 · Cited by 2,043
Wang, K., Tian, J., Zheng, C., Yang, H., Ren, J., Liu, Y., Han, Q., & Zhang, Y. (2021) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2021.104813 · Cited by 361
Rossignol, P., Hernandez, A. F., Solomon, S. D., & Zannad, F. (2019) · The Lancet · doi:10.1016/s0140-6736(18)31808-7 · Cited by 316
Metadata
- Authors
- Dokainish, H., Teo, K., Zhu, J., Roy, A., AlHabib, K. F., ElSayed, A., Palileo-Villaneuva, L., Lopez-Jaramillo, P., Karaye, K., Yusoff, K., Orlandini, A., Sliwa, K., Mondo, C., Lanas, F., Prabhakaran, D., Badr, A., Elmaghawry, M., Damasceno, A., Tibazarwa, K., Belley-Cote, E., Balasubramanian, K., Islam, S., Yacoub, M. H., Huffman, M. D., Harkness, K., Grinvalds, A., McKelvie, R., Bangdiwala, S. I., Yusuf, S., Campos, R., Chacón, C., Cursack, G., Diez, F., Escobar, C., Garcia, C., Vilamajo, O. G., Hominal, M., Ingaramo, A., Kucharczuk, G., Pelliza, M., Rojas, A., Villani, A., Zapata, G., Bourke, P., Lanas, F., Nahuelpan, L., Olivares, C., Riquelme, R., Ai, F., Bai, X., Chen, X., Chen, Y., Gao, M., Ge, C., He, Y., Huang, W., Jiang, H., Liang, T., Liang, X., Liao, Y., Liu, S., Luo, Y., Lu, L., Qin, S., Tan, G., Tan, H., Wang, T., Wang, X., Wei, F., Xiao, F., Zhang, B., Zheng, T., Mendoza, J. L. A., Anaya, M. B., Gomez, E., de Salazar, D. I. M., Quiroz, F., Rodríguez, M. J., Sotomayor, M. S., Navas, A. T., León, M. B., Montalvo, L. A. F., Jaramillo, M. L., Patiño, E. P., Perugachi, C., Trujillo Cruz, F., Elmaghawry, M., Wagdy, K., Bhardwaj, A. K., Chaturvedi, V., Gokhale, G. K., Gupta, R., Honnutagi, R., Joshi, P., Ladhani, S., Negi, P. C., Roy, A., Reddy, N., Abdullah, A., Hassan, M. R. A., Balasinga, M., Kasim, S., Tan, W. Y., Yusoff, K., Damasceno, A., Banze, R., Calua, E., Novela, C., Chemane, J., Akintunde, A. A., Ansa, V., Gbadamosi, H., Karaye, K. M., Mbakwem, A., Mohammed, S., Nwafor, E., Ojji, D., Olunuga, T., Sa'idu, B. O. H., Umuerri, E., Alcaraz, J., Palileo-Villanueva, L., Palomares, E., Timonera, M. R., Badr, A., Alghamdi, S., Alhabib, K., Almasood, A., Alsaif, S., Elasfar, A., Ghabashi, A., Mimish, L., Bester, F., Kelbe, D., Klug, E., Sliwa, K., Tibarzawa, K., Abdalla, O. E., Dimitri, M. E., Mustafa, H., Osman, O., Saad, A., & Mondo, C.
- Venue
- The Lancet Global Health
- Publisher
- Elsevier BV
- Published
- 2017-07
- Volume
- 5
- Issue
- 7
- Pages
- e665-e672
- ISSN
- 2214-109X (ISSN-L)
- OpenAlex
- W2611250527
- Cited by
- 409
- References
- 4
- FWCI
- 23.01
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Global mortality variations in patients with heart failure: results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study. https://app.cochat.ai/papers/10.1016/s2214-109x(17)30196-1
- The paper
- Dokainish, H., Teo, K., Zhu, J., Roy, A., AlHabib, K. F., ElSayed, A., Palileo-Villaneuva, L., Lopez-Jaramillo, P., Karaye, K., Yusoff, K., Orlandini, A., Sliwa, K., Mondo, C., Lanas, F., Prabhakaran, D., Badr, A., Elmaghawry, M., Damasceno, A., Tibazarwa, K., . . . Mondo, C. (2017). Global mortality variations in patients with heart failure: results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study. The Lancet Global Health. https://doi.org/10.1016/s2214-109x(17)30196-1
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
