Comparison of effectiveness and cost-effectiveness of an intensive community supported discharge service versus treatment as usual for adolescents with psychiatric emergencies: a randomised controlled trial
Open accessAbstract
BACKGROUND: Intensive community treatment to reduce dependency on adolescent psychiatric inpatient care is recommended in guidelines but has not been assessed in a randomised controlled trial in the UK. We designed a supported discharge service (SDS) provided by an intensive community treatment team and compared outcomes with usual care. METHODS: Eligible patients for this randomised controlled trial were younger than 18 years and had been admitted for psychiatric inpatient care in the South London and Maudsley NHS Foundation Trust. Patients were assigned 1:1 to either the SDS or to usual care by use of a computer-generated pseudorandom code with random permuted blocks of varying sizes. The primary outcome was number of inpatient bed-days, change in Strengths and Difficulties Questionnaire (SDQ) scores, and change in Children's Global Assessment Scale (CGAS) scores at 6 months, assessed by intention to treat. Cost-effectiveness was explored with acceptability curves based on CGAS scores and quality-adjusted life-years (QALYs) calculated from the three-level EuroQol measure of health-related quality of life (EQ-5D-3L), taking a health and social care perspective. This study is registered with the ISRCTN Registry, number ISRCTN82129964. FINDINGS: Hospital use at 6 months was significantly lower in the SDS group than in the usual care group (unadjusted median 34 IQR 17-63 vs 50 days, 19-125, p=0·04). The ratio of mean total inpatient days for usual care to SDS was 1·67 (95% CI 1·02-2·81, p=0·04), which decreased to 1·65 (0·99-2·77, p=0·057) when adjusted for differences in hospital use before randomisation. Scores for SDQ and CGAS did not differ between groups. The cost-effectiveness acceptability curve based on QALYs showed that the probability of SDS being cost-effective compared with usual care was around 60% with a willingness-to-pay threshold of £20 000-30 000 per QALY, and that based on CGAS showed at least 58% probability of SDS being cost-effective compared with usual care irrespective of willingness to pay. We recorded no adverse events attributable to SDS or usual care. INTERPRETATION: SDS provided by an intensive community treatment team reduced bed usage at 6 months' follow-up but had no effect on functional status and symptoms of mental health disorders compared with usual care. The possibility of preventing admissions, particularly through features such as reduced self-harm and improved reintegration into school, with intensive community treatment should be investigated in future studies. FUNDING: South London and Maudsley NHS Trust.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Intensive community treatment can reduce need for hospital admission among adolescents.
“Intensive community treatment can reduce need for hospital admission among adolescents [42]”
From Social media, internet use and suicide attempts in adolescents (2019) · cites this paper as [42]
The Results (page unavailable) report fewer occupied hospital bed-days for adolescents receiving intensive community supported discharge than for those receiving usual care. But the Abstract’s Interpretation (page unavailable) says whether this treatment can prevent admissions should be investigated in future studies. Reduced hospital use is supported; a reduced need for admission is not established. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
1 retracted
Assertive community treatment for people with severe mental disorders
Marshall, M., & Lockwood, A. (1998) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001089 · Cited by 589 · see citing works
RetractedEuroQol: a new facility for the measurement of health-related quality of life
(1990) · Health Policy · doi:10.1016/0168-8510(90)90421-9 · Cited by 15,736 · see citing works
Multiple imputation using chained equations: Issues and guidance for practice
White, I. R., Royston, P., & Wood, A. M. (2011) · Statistics in Medicine · doi:10.1002/sim.4067 · Cited by 9,792 · see citing works
A Children's Global Assessment Scale (CGAS)
Shaffer, D. (1983) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790100074010 · Cited by 3,716 · see citing works
Self-harm and suicide in adolescents
Hawton, K., Saunders, K. E., & O'Connor, R. C. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60322-5 · Cited by 2,306 · see citing works
Goodman, R. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00494 · Cited by 1,760 · see citing works
Subgroup analysis and other (mis)uses of baseline data in clinical trials
Assmann, S. F., Pocock, S. J., Enos, L. E., & Kasten, L. E. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02039-0 · Cited by 1,167 · see citing works
Manca, A., Hawkins, N., & Sculpher, M. J. (2005) · Health Economics · doi:10.1002/hec.944 · Cited by 1,024 · see citing works
How should cost data in pragmatic randomised trials be analysed?
Thompson, S. G. (2000) · BMJ · doi:10.1136/bmj.320.7243.1197 · Cited by 772 · see citing works
A rational framework for decision making by the National Institute for Clinical Excellence (NICE)
Claxton, K., Sculpher, M., & Drummond, M. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09832-x · Cited by 456 · see citing works
A guide to cost-effectiveness acceptability curves
Fenwick, E. A. L., & Byford, S. (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.187.2.106 · Cited by 420 · see citing works
Self-citationIntensive versus standard case management for severe psychotic illness: a randomised trial
Burns, T., Creed, F. H., Fahy, T., Thompson, S. G., & Tyrer, P. J. (1999) · The Lancet · doi:10.1016/s0140-6736(98)12191-8 · Cited by 321 · see citing works
Multiple Imputation of Missing Values: New Features for Mim
Royston, P. J., Carlin, J. B., & White, I. R. (2009) · The Stata Journal Promoting communications on statistics and Stata · doi:10.1177/1536867x0900900205 · Cited by 217 · see citing works
Byford, S., Harrington, R., Torgerson, D. J., Kerfoot, M., Dyer, E. J., Harrington, V., Woodham, A., Gill, J., & McNiven, F. (1999) · The British Journal of Psychiatry · doi:10.1192/bjp.174.1.56 · Cited by 103 · see citing works
Self-citationReliable Self-Report of Health Service Use by Individuals With Serious Mental Illness
Goldberg, R. W., Seybolt, D. C., & Lehman, A. F. (2002) · Psychiatric Services · doi:10.1176/appi.ps.53.7.879 · Cited by 101 · see citing works
Can You Trust Self-Report Data Provided By Homeless Mentally Ill Individuals?
Calsyn, R. J., Allen, G., Morse, G. A., Smith, R. D., & Tempelhoff, B. (1993) · Evaluation Review · doi:10.1177/0193841x9301700306 · Cited by 94 · see citing works
Mental health provision for young offenders: service use and cost
Barrett, B. M., Byford, S., Chitsabesan, P., & Kenning, C. (2006) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.105.010108 · Cited by 80 · see citing works
Self-citationHarrington, R. (2000) · BMJ · doi:10.1136/bmj.321.7268.1047 · Cited by 80 · see citing works
Wolff, J. C., Frazier, E. A., Esposito-Smythers, C. L., Burke, T. A., Sloan, E., & Spirito, A. (2013) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-013-9743-y · Cited by 74 · see citing works
Review: Alternatives to inpatient care for children and adolescents with mental health disorders
Kwok, R. K. H., Yuan, S. N. V., & Ougrin, D. (2015) · Child and Adolescent Mental Health · doi:10.1111/camh.12123 · Cited by 74 · see citing works
Self-citationBoege, I., Corpus, N., Schepker, R., Kilian, R., & Fegert, J. M. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2015.01.009 · Cited by 60 · see citing works
Reavey, P., Poole, J., Corrigall, R. J., Zundel, T., Byford, S., Sarhane, M., Taylor, E. A., Ivens, J., & Ougrin, D. (2017) · Health & Place · doi:10.1016/j.healthplace.2017.05.008 · Cited by 52 · see citing works
Self-citationOugrin, D., & Boege, I. (2012) · Journal of Adolescence · doi:10.1016/j.adolescence.2012.09.006 · Cited by 50 · see citing works
Self-citationGoodwin, N., & Lawton-Smith, S. H. (2010) · International Journal of Integrated Care · doi:10.5334/ijic.516 · Cited by 45 · see citing works
Worrall, A., O’Herlihy, A., Banerjee, S., et al. (2004) · BMJ · doi:10.1136/bmj.38058.605787.ae · Cited by 39 · see citing works
Morriss, R. K., Garland, A., Nixon, N. L., Guo, B., James, M., Kaylor‐Hughes, C., Moore, R. G., Ramana, R., Sampson, C., Sweeney, T., et al. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)30143-2 · Cited by 38 · see citing works
Ougrin, D., Zundel, T., Corrigall, R. J., Padmore, J., & Loh, C. B.-L. (2013) · Child and Adolescent Mental Health · doi:10.1111/camh.12038 · Cited by 37 · see citing works
Self-citationBehandelt zu Hause Gesund werden
Boege, I., Copus, N., & Schepker, R. (2013) · Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie · doi:10.1024/1422-4917/a000267 · Cited by 35 · see citing works
Suicide survey in a London borough: primary care and public health perspectives
Ougrin, D., Banarsee, R., Dunn-Toroosian, V., & Majeed, A. (2010) · Journal of Public Health · doi:10.1093/pubmed/fdq094 · Cited by 30 · see citing works
Self-citationService innovations: rethinking in-patient provision for adolescents
Corrigall, R., & Mitchell, B. (2002) · Psychiatric Bulletin · doi:10.1192/pb.26.10.388 · Cited by 23 · see citing works
Self-citationKillaspy, H. T., Mas-Expósito, L., Marston, L., & King, M. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0296-6 · Cited by 19 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [18]NICE Guide to the methods of technology appraisal 2013 2013 National Institute of Health and Care Excellence London 27905712
Cited by
Sorted by citations
Social media, internet use and suicide attempts in adolescents
Sedgwick, R., Epstein, S., Dutta, R., & Ougrin, D. (2019) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000547 · Cited by 260 · see citing works
Self-citationKothgassner, O. D., Robinson, K., Goreis, A., Ougrin, D., & Plener, P. L. (2020) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-020-00123-9 · Cited by 163 · see citing works
“Recent studies have shown that longer inpatient admissions might be linked with increased risk of self-harm in young people [58, 62].”
BackgroundSelf-citationJuul, S., Gluud, C., Simonsen, S., Frandsen, F. W., Kirsch, I., & Jakobsen, J. C. (2021) · BMJ Evidence-Based Medicine · doi:10.1136/bmjebm-2020-111407 · Cited by 135 · see citing works
Iyengar, U., Snowden, N., Asarnow, J. R., Moran, P., Tranah, T., & Ougrin, D. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00583 · Cited by 111 · see citing works
Self-citationAsarnow, J. R., & Mehlum, L. (2019) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13130 · Cited by 100 · see citing works
Steinhoff, A., Ribeaud, D., Kupferschmid, S., Raible-Destan, N., Quednow, B. B., Hepp, U., Eisner, M., & Shanahan, L. (2021) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-020-01573-w · Cited by 100 · see citing works
Bahji, A., Pierce, M., Wong, J., Roberge, J. N., Ortega, I., & Patten, S. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.6614 · Cited by 60 · see citing works
Vusio, F., Thompson, A., Birchwood, M., & Clarke, L. (2020) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-019-01420-7 · Cited by 27 · see citing works
- Authors
- Ougrin, D., Corrigall, R., Poole, J., Zundel, T., Sarhane, M., Slater, V., Stahl, D., Reavey, P., Byford, S., Heslin, M., Ivens, J., Crommelin, M., Abdulla, Z., Hayes, D., Middleton, K., Nnadi, B., & Taylor, E.
- Affiliations
- King's College London (GB)
- South London and Maudsley NHS Foundation Trust (GB)
- London South Bank University (GB)
- Corresponding author
- Ougrin, Dennis
- Venue
- The Lancet Psychiatry
- Publisher
- Elsevier BV
- Published
- 2018-06
- Volume
- 5
- Issue
- 6
- Pages
- 477-485
- ISSN
- 2215-0366 (ISSN-L)
- PMC
- PMC5994473
- OpenAlex
- W2799609585
- Cited by
- 101
- References
- 31
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 15 · 2023: 9 · 2022: 3 · 2021: 21 · 2020: 17 · 2019: 11 · 2018: 7
- FWCI
- 16.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- The Lancet Psychiatry (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Research Open (London South Bank University) (acceptedVersion, cc-by-nc-nd)
- Research Open (London South Bank University) (acceptedVersion)
- Research Portal (King's College London) (submittedVersion, cc-by-nc-nd)
- Funders
- South London and Maudsley NHS Foundation Trust
- NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research
- National Institute for Health and Care Research
- King's College London
- National Institutes of Health
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Health Sciences › Medicine › Emergency Medicine › Emergency and Acute Care Studies
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- psychiatric inpatient care, community mental health services, hospital readmission, cost-effectiveness, quality-adjusted life years, hospital bed days, adolescents
- MeSH terms
- Adolescent, Mental Disorders, Child, Community Mental Health Services, Cost-Benefit Analysis, Emergency Services, Psychiatric, Female, Humans, Male, Neuropsychological Tests, Patient Discharge, Quality of Life
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review