The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology
Open accessAbstract
Andrographis paniculata Wall (family Acanthaceae) is one of the most popular medicinal plants used traditionally for the treatment of array of diseases such as cancer, diabetes, high blood pressure, ulcer, leprosy, bronchitis, skin diseases, flatulence, colic, influenza, dysentery, dyspepsia and malaria for centuries in Asia, America and Africa continents. It possesses several photochemical constituents with unique and interesting biological properties. This review describes the past and present state of research on Andrographis paniculata with respect to the medicinal usage, phytochemistry, pharmacological activities, toxicity profile and therapeutic usage, in order to bridge the gap requiring future research opportunities. This review is based on literature study on scientific journals and books from library and electronic sources. Diterpenes, flavonoids, xanthones, noriridoides and other miscellaneous compounds have been isolated from the plant. Extract and pure compounds of the plant have been reported for their anti-microbial, cytotoxicity, anti-protozoan, anti-inflammatory, anti-oxidant, immunostimulant, anti-diabetic, anti-infective, anti-angiogenic, hepato-renal protective, sex hormone/sexual function modulation, liver enzymes modulation insecticidal and toxicity activities. The results of numerous toxicity evaluations of extracts and metabolites isolated from this plant did not show any significant acute toxicity in experimental animals. Detailed and more comprehensive toxicity profile on mammalian tissues and organs is needed in future studies.
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Cites
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Cited by
Wound Healing and the Use of Medicinal Plants
Shedoeva, A., Leavesley, D., Upton, Z., & Fan, C. (2019) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2019/2684108 · Cited by 420
Fardiyah, Q., Ersam, T., Suyanta, Slamet, A., Suprapto, & Kurniawan, F. (2020) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2020.10.015 · Cited by 51
Fitrasyah, S. I., Ariani, A., Rahman, N., Nurulfuadi, N., Aiman, U., Nadila, D., Pradana, F., Rakhman, A., & Hartini, D. A. (2021) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2021.5872 · Cited by 12
Metadata
- Authors
- Okhuarobo, A., Ehizogie Falodun, J., Erharuyi, O., Imieje, V., Falodun, A., & Langer, P.
- Venue
- Asian Pacific Journal of Tropical Disease
- Publisher
- Elsevier BV
- Published
- 2014-06
- Volume
- 4
- Issue
- 3
- Pages
- 213-222
- ISSN
- 2222-1808 (ISSN-L)
- OpenAlex
- W2054618769
- Cited by
- 289
- References
- 27
- FWCI
- 16.99
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Okhuarobo, A., Ehizogie Falodun, J., Erharuyi, O., Imieje, V., Falodun, A., & Langer, P. (2014). Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pacific Journal of Tropical Disease. https://doi.org/10.1016/s2222-1808(14)60509-0
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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