The DOI matches its Crossref record; 106 of the 106 references it cites were found in a registry or an index.
A global scientific strategy to cure hepatitis B
Open accessAbstract
Chronic hepatitis B virus (HBV) infection is a global public health challenge on the same scale as tuberculosis, HIV, and malaria. The International Coalition to Eliminate HBV (ICE-HBV) is a coalition of experts dedicated to accelerating the discovery of a cure for chronic hepatitis B. Following extensive consultation with more than 50 scientists from across the globe, as well as key stakeholders including people affected by HBV, we have identified gaps in our current knowledge and new strategies and tools that are required to achieve HBV cure. We believe that research must focus on the discovery of interventional strategies that will permanently reduce the number of productively infected cells or permanently silence the covalently closed circular DNA in those cells, and that will stimulate HBV-specific host immune responses which mimic spontaneous resolution of HBV infection. There is also a pressing need for the establishment of repositories of standardised HBV reagents and protocols that can be accessed by all HBV researchers throughout the world. The HBV cure research agenda outlined in this position paper will contribute markedly to the goal of eliminating HBV infection worldwide.
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Cites
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
Lampertico, P., Agarwal, K., Berg, T., Buti, M., Janssen, H. L. A., Papatheodoridis, G., Zoulim, F., & Tacke, F. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.03.021 · Cited by 5,391
Self-citationYan, H., Zhong, G., Xu, G., He, W., Jing, Z., Gao, Z., Huang, Y., Qi, Y., Peng, B., Wang, H., et al. (2012) · eLife · doi:10.7554/elife.00049 · Cited by 2,115
Self-citationRazavi-Shearer, D., Gamkrelidze, I., Nguyen, M. H., Chen, D.-S., Van Damme, P., Abbas, Z., Abdulla, M., Abou Rached, A., Adda, D., Aho, I., et al. (2018) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(18)30056-6 · Cited by 1,661
Self-citationHepatitis B Virus Immunopathogenesis
Chisari, F. V. (1995) · Annual Review of Immunology · doi:10.1146/annurev.immunol.13.1.29 · Cited by 1,609
Self-citationStanaway, J. D., Flaxman, A. D., Naghavi, M., Fitzmaurice, C., Vos, T., Abubakar, I., Abu-Raddad, L. J., Assadi, R., Bhala, N., Cowie, B., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)30579-7 · Cited by 1,358
Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection
Guidotti, L. G., Rochford, R., Chung, J., Shapiro, M., Purcell, R., & Chisari, F. V. (1999) · Science · doi:10.1126/science.284.5415.825 · Cited by 1,223
Self-citationThimme, R., Wieland, S., Steiger, C., Ghrayeb, J., Reimann, K. A., Purcell, R. H., & Chisari, F. V. (2003) · Journal of Virology · doi:10.1128/jvi.77.1.68-76.2003 · Cited by 979
Self-citationCharacterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection
Boni, C., Fisicaro, P., Valdatta, C., Amadei, B., Di Vincenzo, P., Giuberti, T., Laccabue, D., Zerbini, A., Cavalli, A., Missale, G., et al. (2007) · Journal of Virology · doi:10.1128/jvi.02844-06 · Cited by 920
Self-citationWerle–Lapostolle, B., Bowden, S., Locarnini, S., Wursthorn, K., Petersen, J., Lau, G., Trepo, C., Marcellin, P., Goodman, Z., & Delaney IV, W. E. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.03.018 · Cited by 905
Self-citationHBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B
Nassal, M. (2015) · Gut · doi:10.1136/gutjnl-2015-309809 · Cited by 899
Cited by
Immunobiology and pathogenesis of hepatitis B virus infection
Iannacone, M., & Guidotti, L. G. (2022) · Nature Reviews Immunology · doi:10.1038/s41577-021-00549-4 · Cited by 520
Self-citationOptimization of AAV vectors to target persistent viral reservoirs
Colón-Thillet, R., Jerome, K. R., & Stone, D. (2021) · Virology Journal · doi:10.1186/s12985-021-01555-7 · Cited by 50
Li, J., Lin, Y., Wang, X., & Lu, M. (2024) · Virologica Sinica · doi:10.1016/j.virs.2024.01.001 · Cited by 9
Metadata
- Authors
- Revill, P. A., Chisari, F. V., Block, J. M., Dandri, M., Gehring, A. J., Guo, H., Hu, J., Kramvis, A., Lampertico, P., Janssen, H. L. A., Levrero, M., Li, W., Liang, T. J., Lim, S.-G., Lu, F., Penicaud, M. C., Tavis, J. E., Thimme, R., Arbuthnot, P., Boonstra, A., Chang, K.-M., Chen, P.-J., Glebe, D., Guidotti, L. G., Fellay, J., Ferrari, C., Jansen, L., Lau, D. T. Y., Lok, A. S., Maini, M. K., Mason, W., Matthews, G., Paraskevis, D., Petersen, J., Rehermann, B., Shin, E.-C., Thompson, A., van Bömmel, F., Wang, F.-S., Watashi, K., Yang, H.-C., Yuan, Z., Yuen, M.-F., Block, T., Miller, V., Protzer, U., Bréchot, C., Locarnini, S., Peters, M. G., Schinazi, R. F., & Zoulim, F.
- Venue
- The Lancet Gastroenterology & Hepatology
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 4
- Issue
- 7
- Pages
- 545-558
- ISSN
- 2468-1156 (ISSN-L)
- 2468-1253
- OpenAlex
- W2938013723
- Cited by
- 508
- References
- 106
- FWCI
- 40.57
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Revill, P. A., Chisari, F. V., Block, J. M., Dandri, M., Gehring, A. J., Guo, H., Hu, J., Kramvis, A., Lampertico, P., Janssen, H. L. A., Levrero, M., Li, W., Liang, T. J., Lim, S.-G., Lu, F., Penicaud, M. C., Tavis, J. E., Thimme, R., Arbuthnot, P., . . . Zoulim, F. (2019). A global scientific strategy to cure hepatitis B. The Lancet Gastroenterology & Hepatology. https://doi.org/10.1016/s2468-1253(19)30119-0
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
