Growth factors for bone growth and repair: IGF, TGFβ and BMP

Mechanism of activation of the TGF-β receptor

Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., & Massagué, J. (1994) · Nature · doi:10.1038/370341a0 · Cited by 2,340 · see citing works

Nutritional Regulation of the Insulin-Like Growth Factors*

Thissen, J., Ketelslegers, J., & Underwood, L. E. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-1-80 · Cited by 1,578 · see citing works

Limb alterations in brachypodism mice due to mutations in a new member of the TGFβ-superfamily

Storm, E. E., Huynh, T. V., Copeland, N. G., Jenkins, N. A., Kingsley, D. M., & Lee, S. M. (1994) · Nature · doi:10.1038/368639a0 · Cited by 855 · see citing works

Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

ten Dijke, P., Yamashita, H., Sampath, T. K., Reddi, A. H., Estevez, M., Riddle, D. L., Ichijo, H., Heldin, C., & Miyazono, K. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32506-1 · Cited by 730 · see citing works

The bone morphogenetic protein family and osteogenesis

Wozney, J. M. (1992) · Molecular Reproduction and Development · doi:10.1002/mrd.1080320212 · Cited by 684 · see citing works

Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

Shimasaki, S., & LING, N. C. (1991) · Progress in Growth Factor Research · doi:10.1016/0955-2235(91)90003-m · Cited by 678 · see citing works

Regulation of Fracture Repair by Growth Factors

Bolander, M. E. (1992) · Experimental Biology and Medicine · doi:10.3181/00379727-200-43410a · Cited by 637 · see citing works

Bone Growth Factors

Mohan, S., & Baylink, D. J. (1991) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199102000-00004 · Cited by 533 · see citing works

Transforming Growth Factor-β Gene Family Members and Bone*

Horowitz, M. C., Wozney, J. M., & McCarthy, T. L. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-1-27 · Cited by 496 · see citing works

Transforming growth factor beta: the good, the bad, and the ugly.

Wahl, S. M. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.5.1587 · Cited by 486 · see citing works

The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defects.

Cook, S. D., BAFFES, G. C., Wolfe, M. W., et al. (1994) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-199406000-00006 · Cited by 381 · see citing works

Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing

Bostrom, M. P., Lane, J. M., Berberian, W. S., et al. (1995) · Journal of Orthopaedic Research® · doi:10.1002/jor.1100130309 · Cited by 374 · see citing works

Characterization and Cloning of a Receptor for BMP-2 and BMP-4 from NIH 3T3 Cells

Koenig, B. B., Cook, J. S., Wolsing, D. H., Ting, J., Tiesman, J. P., Correa, P. E., Olson, C. A., Pecquet, A. L., Ventura, F., Grant, R. A., et al. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.9.5961 · Cited by 366 · see citing works

Recombinant Human Bone Morphogenetic Protein-7 Induces Healing in a Canine Long-Bone Segmental Defect Model

Cook, S. D., BAFFES, G. C., WOLFE, M. W., et al. (1994) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199404000-00046 · Cited by 336 · see citing works

Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing

Nakase, T., Nomura, S., Yoshikawa, H., et al. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650090510 · Cited by 332 · see citing works

Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts

Harris, S. E., Bonewald, L. F., Harris, M. A., Sabatini, M., Dallas, S. L., Feng, J. Q., Ghosh‐Choudhury, N., Wozney, J. M., & Mundy, G. R. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650090611 · Cited by 325 · see citing works

Studies on the Mechanisms by Which Insulin-like Growth Factor (IGF) Binding Protein-4 (IGFBP-4) and IGFBP-5 Modulate IGF Actions in Bone Cells

Mohan, S., Nakao, Y., Honda, Y., et al. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.35.20424 · Cited by 310 · see citing works

Healing Segmental Femoral Defects in Sheep Using Recombinant Human Bone Morphogenetic Protein

Gerhart, T. N., Kirker‐Head, C. A., KRIZ, M. J., et al. (1993) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199308000-00043 · Cited by 307 · see citing works

Role of active and latent transforming growth factor β in bone formation

Bonewald, L. F., & Dallas, S. L. (1994) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240550312 · Cited by 297 · see citing works

Induction of Dentin Formation on Canine Amputated Pulp by Recombinant Human Bone Morphogenetic Proteins (BMP)-2 and -4

Nakashima, M. (1994) · Journal of Dental Research · doi:10.1177/00220345940730090601 · Cited by 275 · see citing works

Modulation of Transforming Growth Factor-βProduction in Normal Human Osteoblast-Like Cells by 17β-Estradiol and Parathyroid Hormone

Oursler, M. J., CORTESE, C., Keeting, P. E., Anderson, M. A., Bonde, S. K., Riggs, B. L., & Spelsberg, T. C. (1991) · Endocrinology · doi:10.1210/endo-129-6-3313 · Cited by 263 · see citing works

BMP5 and the Molecular, Skeletal, and Soft-Tissue Alterations in short ear Mice

King, J. A., Marker, P. C., Seung, K. J., & Kingsley, D. M. (1994) · Developmental Biology · doi:10.1006/dbio.1994.1300 · Cited by 256 · see citing works

Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

ten Dijke, P., Miyazono, K., & Heldin, C. (1996) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(96)80058-5 · Cited by 254 · see citing works

Insulin-like growth factor-I supports formation and activation of osteoclasts

Mochizuki, H., Hakeda, Y., Wakatsuki, N., et al. (1992) · Endocrinology · doi:10.1210/endo.131.3.1505451 · Cited by 250 · see citing works

Osteogenin and recombinant bone morphogenetic protein 2B are chemotactic for human monocytes and stimulate transforming growth factor beta 1 mRNA expression.

Cunningham, N. S., Paralkar, V. M., & Reddi, A. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.24.11740 · Cited by 241 · see citing works

Transforming growth factor-beta in the regulation of fracture repair.

Joyce, M. E., Jingushi, S., & Bolander, M. E. (1990) · PubMed · Cited by 240 · see citing works

Insulin-like Growth Factors and Bone: The Osteoporosis Connection

Rosen, C. J., Donahue, L. R., & Hunter, S. J. (1994) · Experimental Biology and Medicine · doi:10.3181/00379727-206-43726 · Cited by 228 · see citing works

In vivo actions of insulin-like growth factor-I (IGF-I) on bone formation and resorption in rats

Spencer, E., Liu, C. C., Si, E. C. C., & Howard, G. A. (1991) · Bone · doi:10.1016/8756-3282(91)90050-s · Cited by 222 · see citing works

Increased Activity of Insulin-Like Growth Factor (IGF) in Osteoblastic Cells in the Presence of Growth Hormone (GH): Positive Correlation with the Presence of the GHInduced IGF-Binding Protein BP-3

Ernst, M., & Rodan, G. A. (1990) · Endocrinology · doi:10.1210/endo-127-2-807 · Cited by 218 · see citing works

Transforming growth factor-β enhances fracture healing in rabbit tibiae

Lind, M., Schumacker, B., Søballé, K., Keller, J. O., Melsen, F., & Bünger, C. E. (1993) · Acta Orthopaedica Scandinavica · doi:10.3109/17453679308993691 · Cited by 217 · see citing works

Gene Expression During Bone Repair

Sandberg, M., Aro, H. T., & VUORIO, E. I. (1993) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199304000-00043 · Cited by 211 · see citing works

Mechanical loading stimulates rapid changes in periosteal gene expression

Cullen, D. M., Thiede, M. A., Petersen, D. N., Kimmel, D. B., & Recker, R. R. (1994) · Calcified Tissue International · doi:10.1007/bf00298562 · Cited by 211 · see citing works

Age-related decreases in insulin-like growth factor-I and transforming growth factor-beta in femoral cortical bone from both men and women: implications for bone loss with aging

Nicolas, V., Prewett, A., Bettica, P. U., Mohan, S., Finkelman, R. D., Baylink, D. J., & Farley, J. R. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.78.5.8175953 · Cited by 209 · see citing works

Transforming Growth Factor-β: Latent Forms, Binding Proteins and Receptors

Miyazono, K., Ichijo, H., & Heldin, C. (1993) · Growth Factors · doi:10.3109/08977199309029130 · Cited by 209 · see citing works

Skeletal Growth Factors

CANALIS, E. M. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-375098-3.50020-2 · Cited by 208 · see citing works

Transforming Growth Factor-β in the Regulation of Fracture Repair

Joyce, M. E., Jingushi, S., & Bolander, M. E. (1990) · Orthopedic Clinics of North America · doi:10.1016/s0030-5898(20)31576-5 · Cited by 208 · see citing works

Journal of Bone and Mineral Research

Reddi, A. H., & Cunningham, N. S. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650081313 · Cited by 204 · see citing works

Generalized osteoarthritis associated with increased insulin‐like growth factor types i and ii and transforming growth factor β in cortical bone from the iliac crest. possible mechanism of increased bone density and protection against osteoporosis

Dequeker, J., Mohan, S., Finkelman, R. D., et al. (1993) · Arthritis & Rheumatism · doi:10.1002/art.1780361209 · Cited by 191 · see citing works

TGF-β1 induces bone closure of skull defects: Temporal dynamics of bone formation in defects exposed to rhTGF-β1

Beck, L. S., Amento, E. P., Xu, Y., Deguzman, L., Lee, W. P., Nguyen, T. H., & Gillett, N. A. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650080614 · Cited by 175 · see citing works

Short-term effects of recombinant human insulin-like growth factor I on bone turnover in normal women

Ebeling, P. R., Jones, J. D., O’Fallon, W. M., Janes, C. H., & Riggs, B. L. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.77.5.8077337 · Cited by 174 · see citing works

Characterization and autoregulation of latent transforming growth factor beta (TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent TGF beta-binding protein.

Dallas, S. L., Park-Snyder, S., Miyazono, K., Twardzik, D. R., Mundy, G. R., & Bonewald, L. F. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37449-5 · Cited by 171 · see citing works

Local injection of TGF-β increases the strength of tibial fractures in the rat

Nielsen, H. M., Andreassen, T. T., Ledet, T., & Oxlund, H. (1994) · Acta Orthopaedica Scandinavica · doi:10.3109/17453679408993715 · Cited by 158 · see citing works

Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function.

Hill, P. A., Reynolds, J. J., & Meikle, M. C. (1995) · Endocrinology · doi:10.1210/endo.136.1.7828521 · Cited by 157 · see citing works

Recombinant Vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo.

Gitelman, S. E., Kobrin, M. S., Ye, J.-Q., et al. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.126.6.1595 · Cited by 155 · see citing works

Expression of bone morphogenetic protein messenger RNAs by normal rat and human prostate and prostate cancer cells

Harris, S. E., Harris, M. A., Mahy, P., Feng, J. Q., Mundy, G. R., & Wozney, J. M. (1994) · The Prostate · doi:10.1002/pros.2990240406 · Cited by 144 · see citing works

Glucocorticoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells.

Okazaki, R., Riggs, B. L., & Conover, C. A. (1994) · Endocrinology · doi:10.1210/endo.134.1.7506203 · Cited by 141 · see citing works

Insulin-like growth factor-I increases trabecular bone formation and osteoblastic cell proliferation in unloaded rats

Machwate, M., Zérath, E., Holy, X., Pastoureau, P., & Marie, P. J. (1994) · Endocrinology · doi:10.1210/endo.134.3.8119139 · Cited by 141 · see citing works

High-Affinity Androgen Binding and Androgenic Regulation of α1(I)-Procollagen and Transforming Growth Factor-β Steady State Messenger Ribonucleic Acid Levels in Human Osteoblast-Like Osteosarcoma Cells*

Benz, D., Haussler, M. R., Thomas, M. A., Speelman, B. A., & Komm, B. S. (1991) · Endocrinology · doi:10.1210/endo-128-6-2723 · Cited by 139 · see citing works

Insulin‐Like Growth Factor (IGF) Binding Proteins: the Role of Serum IGFBPs in Regulating IGF Availability

Baxter, R. C. (1991) · Acta Paediatrica · doi:10.1111/j.1651-2227.1991.tb17983.x · Cited by 130 · see citing works

Ovariectomy selectively reduces the concentration of transforming growth factor beta in rat bone: implications for estrogen deficiency-associated bone loss.

Finkelman, R. D., Bell, N. H., Strong, D. D., DEMERS, L. M., & Baylink, D. J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.24.12190 · Cited by 129 · see citing works

Complex pattern of insulin‐like growth factor binding protein expression in primary rat osteoblast enriched cultures: Regulation by prostaglandin E2, growth hormone, and the insulin‐like growth factors

McCarthy, T. L., Casinghino, S. R., & CANALIS, E. M. (1994) · Journal of Cellular Physiology · doi:10.1002/jcp.1041600119 · Cited by 125 · see citing works

Evaluation of Human Bone Morphogenetic Protein 2 in a Canine Spinal Fusion Model

Muschler, G. F., Hyodo, A., Manning, T., KAMBIC, H. E., & Easley, K. A. (1994) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199411000-00033 · Cited by 121 · see citing works

Plasminogen‐dependent activation of latent transforming growth factor beta (TGFβ) by growing cultures of osteoblast‐like cells

Yee, J. A., Yan, L., Dominguez, J. C., Allan, E. H., & Martin, T. J. (1993) · Journal of Cellular Physiology · doi:10.1002/jcp.1041570312 · Cited by 120 · see citing works

The effect of exogenous transforming growth factor-β2 on healing fractures in the rabbit

Critchlow, M. A., Bland, Y. S., & Ashhurst, D. E. (1995) · Bone · doi:10.1016/8756-3282(95)00085-r · Cited by 119 · see citing works

Benefit of systemically administered rhIGF-I and rhIGF-I/IGFBP-3 on cancellous bone in ovariectomized rats

Bagi, C. M., Brommage, R., Deleon, L., Adams, S., Rosen, D. M., & Sommer, A. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650090820 · Cited by 119 · see citing works

Insulin-like growth factor binding proteins in bone cell regulation.

Mohan, S. (1993) · PubMed · Cited by 113 · see citing works

Insulinlike growth factor gene expression in human fracture callus

Andrew, J. G., Hoyland, J. A., Freemont, A. J., et al. (1993) · Calcified Tissue International · doi:10.1007/bf01321886 · Cited by 112 · see citing works

Bone grafts, derivatives and substitutes

Klenerman, L. (1994) · British Journal of Plastic Surgery · doi:10.1016/0007-1226(94)90155-4 · Cited by 111 · see citing works

Expression of mRNA for IL1 beta, IL6 and TGF beta 1 in developing human bone and cartilage.

Dodds, R. A., Merry, K., Littlewood, A. J., & Gowen, M. (1994) · Journal of Histochemistry & Cytochemistry · doi:10.1177/42.6.8189035 · Cited by 110 · see citing works

Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction.

Finkelman, R. D., Linkhart, T. A., Mohan, S., Lau, K. ‐. W., Baylink, D. J., & Bell, N. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.9.3657 · Cited by 105 · see citing works

Serine/threonine kinase receptors

ten Dijke, P., Franzèn, P., Yamashita, H., Ichijo, H., Heldin, C., & Miyazono, K. (1994) · Progress in Growth Factor Research · doi:10.1016/0955-2235(94)90017-5 · Cited by 88 · see citing works

Osteogenic Protein-1 Stimulates Proliferation and Differentiation of Human Bone Cells in Vitro

Knutsen, R., Wergedal, J. E., Sampath, T. K., et al. (1993) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1993.1973 · Cited by 87 · see citing works

The Effects of Insulin-like Growth Factor-1 on Critical-Size Calvarial Defects in Sprague—Dawley Rats

Thaller, S. R., Dart, A. J., & Tesluk, H. (1993) · Annals of Plastic Surgery · doi:10.1097/00000637-199311000-00007 · Cited by 85 · see citing works

O’ Bone Graft Derivatives and Substitutes.

Urist, M. R., O'Connor, B. T., & Burwell, R. G. (1994) · Butterworth-Heinemann eBooks · Cited by 82 · see citing works

Regional variation of insulin-like growth factor-I gene expression in mature rat bone and cartilage

Lazowski, D.-A., Fraher, L. J., Hodsman, A. B., Steer, B. M., Modrowski, D., & Han, V. K. M. (1994) · Bone · doi:10.1016/8756-3282(94)90282-8 · Cited by 75 · see citing works

Pulsating Electromagnetic Field Stimulates mRNA Expression of Bone Morphogenetic Protein-2 and -4

Nagai, M., & Ota, M. (1994) · Journal of Dental Research · doi:10.1177/00220345940730100401 · Cited by 73 · see citing works

Systemic administration of recombinant transforming growth factor beta 2 (rTGF-β2) stimulates parameters of cancellous bone formation in juvenile and adult rats

Rosen, D., Miller, S. C., DeLeon, E., Thompson, A. Y., Bentz, H., Mathews, M. C., & Adams, S. (1994) · Bone · doi:10.1016/8756-3282(94)90300-x · Cited by 73 · see citing works

IGF-I and pamidronate increase bone mineral density in ovariectomized adult rats

Ammann, P., Rizzoli, R., Müller, K., et al. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.5.e770 · Cited by 71 · see citing works

An age-related decrease in the concentration of insulin-like growth factor binding protein-5 in human cortical bone

Nicolas, V., Mohan, S., Honda, Y., et al. (1995) · Calcified Tissue International · doi:10.1007/bf00310260 · Cited by 70 · see citing works

Insulinlike growth factor II and transforming growth factor β regulate collagen expression in human osteoblastlike cells in vitro

Strong, D. D., Beachler, A. L., Wergedal, J. E., et al. (1991) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650060105 · Cited by 70 · see citing works

Regulation of insulin-like growth factor system components by osteogenic protein-1 in human bone cells.

Knutsen, R., Honda, Y., Strong, D. D., et al. (1995) · Endocrinology · doi:10.1210/endo.136.3.7532581 · Cited by 64 · see citing works

Bone morphogenetic protein 2 stimulates osteogenesis but does not affect chondrogenesis in osteochondrogenic differentiation of periosteum-derived cells

Iwasaki, M., Nakahara, H., Nakase, T., et al. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650090809 · Cited by 63 · see citing works

1,25-Dihydroxyvitamin D3 increases secretion of insulin-like growth factor binding protein-4 (IGFBP-4) by human osteoblast-like cells in vitro and elevates IGFBP-4 serum levels in vivo.

SCHARLA, S. H., Strong, D. D., Rosen, C. J., et al. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.77.5.7521341 · Cited by 61 · see citing works

Effects of transforming growth factor beta (TGFβ) and 1,25 dihydroxyvitamin D3 on the function, cytochemistry and morphology of normal human osteoblast-like cells

Ingram, R. T., Bonde, S. K., Riggs, B. L., & Fitzpatrick, L. A. (1994) · Differentiation · doi:10.1046/j.1432-0436.1994.5520153.x · Cited by 60 · see citing works

Autocrine regulators of MC3T3-E1 cell proliferation

Amarnani, S. N., Merriman, H. L., Linkhart, T. A., et al. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650080206 · Cited by 58 · see citing works

Bone morphogenetic protein 2 increases insulin-like growth factor I and II transcripts and polypeptide levels in bone cell cultures

CANALIS, E. M., & Gabbitas, B. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650091221 · Cited by 53 · see citing works

Expression of insulin-like growth factor I messenger ribonucleic acid in regenerating bone after fracture: Influence of indomethacin

Edwall, D., Prisell, P. T., Levinovitz, A., Jennische, E., & Norstedt, G. (1992) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650070212 · Cited by 53 · see citing works

Differentiation of normal human bone cells by transforming growth factor-β and 1,25(OH)2 vitamin D3

Wergedal, J. E., Matsuyama, T., & Strong, D. D. (1992) · Metabolism · doi:10.1016/0026-0495(92)90189-h · Cited by 49 · see citing works

Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function

Hill, P. (1995) · Endocrinology · doi:10.1210/en.136.1.124 · Cited by 44 · see citing works

Molecular Cloning of Rat Bone Morphogenetic Protein (BMP) Type IA Receptor and Its Expression During Ectopic Bone Formation Induced by BMP

Takeda, K., Oida, S., Ichijo, H., et al. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.2445 · Cited by 41 · see citing works

Stimulation of trabecular bone formation by insulin-like growth factor I in adult ovariectomized rats

Mueller, K., Cortesi, R., Modrowski, D., & Marie, P. J. (1994) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1994.267.1.e1 · Cited by 40 · see citing works

Transforming growth factor-beta inhibition of mineralization by neonatal rat osteoblasts in monolayer and collagen gel culture

Talley-Ronsholdt, D. J., Lajiness, E. J., & Nagodawithana, K. (1995) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/bf02634001 · Cited by 39 · see citing works

Expression of insulin-like growth factors during bone induction in rat

Prisell, P. T., Edwall, D., Lindblad, J. B., et al. (1993) · Calcified Tissue International · doi:10.1007/bf01321838 · Cited by 38 · see citing works

Recombinant human bone morphogenetic protein‐2 enhances expression of interleukin‐6 and transforming growth factor‐β1 genes in normal human osteoblast‐like cells

Zheng, M., Wood, D. J., Wysocki, S. J., Papadimitriou, J. M., & Wang, E. H. A. (1994) · Journal of Cellular Physiology · doi:10.1002/jcp.1041590111 · Cited by 37 · see citing works

Elevated IGF-II and TGF- beta Concntrations in Human Calvarial Bone

Finelman, R. D., Eason, A. L., Rakijian, D. R., et al. (1994) · Plastic & Reconstructive Surgery · doi:10.1097/00006534-199404000-00012 · Cited by 35 · see citing works

Interleukin-1 stimulates release of insulin-like growth factor-I from neonatal mouse calvaria by a prostaglandin synthesis-dependent mechanism.

Linkhart, T. A., & MacCharles, D. C. (1992) · Endocrinology · doi:10.1210/endo.131.5.1425428 · Cited by 34 · see citing works

Osteoblast-Specific Expression of the α2(I) Collagen Promoter in Transgenic Mice: Correlation with the Distribution of TGF-β1

D’Souza, R. N., Niederreither, K., & Crombrugghe, B. D. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650080914 · Cited by 33 · see citing works

Glucocorticoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells

Okazaki, R. (1994) · Endocrinology · doi:10.1210/en.134.1.126 · Cited by 33 · see citing works

Osteoinductive Proteins

Elima, K. (1993) · Annals of Medicine · doi:10.3109/07853899309147302 · Cited by 32 · see citing works

1,25-Dihydroxyvitamin D3 increases secretion of insulin-like growth factor binding protein-4 (IGFBP-4) by human osteoblast-like cells in vitro and elevates IGFBP-4 serum levels in vivo

Scharla, S. H. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.77.5.1190 · Cited by 26 · see citing works

Regulation of insulin-like growth factor system components by osteogenic protein-1 in human bone cells

Knutsen, R. (1995) · Endocrinology · doi:10.1210/en.136.3.857 · Cited by 26 · see citing works

Early histologic response to titanium implants complexed with bovine bone morphogenetic protein

Yan, J. Q., Wang, X., Baolin, L., et al. (1994) · Journal of Prosthetic Dentistry · doi:10.1016/0022-3913(94)90469-3 · Cited by 25 · see citing works

Bone induction and bone repair by composites of bone morphogenetic protein and biodegradable synthetic polymers.

Miyamoto, S., & Takaoka, K. (1993) · PubMed · Cited by 22 · see citing works

Osteogenic activity of bone morphogenetic protein and hydroxyapatite composite implants.

Herr, G., Wahl, D., & Küsswetter, W. (1993) · PubMed · Cited by 20 · see citing works

Changes in bone inducing activity of bone morphogenetic protein with aging.

Bessho, K., & Iizuka, T. (1993) · PubMed · Cited by 20 · see citing works

Factors which stimulate bone growth in vivo.

Mundy, G. R. (1993) · PubMed · Cited by 19 · see citing works

Interleukin-1 stimulates release of insulin-like growth factor-I from neonatal mouse calvaria by a prostaglandin synthesis-dependent mechanism

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