A clinical review of 128 cases of head and neck tuberculosis presenting over a 10-year period in Bradford, UK
Abstract
Aims: To analyse the epidemiology, presentation and diagnosis of head and neck tuberculosis (TB). Methods: We conducted a 10-year retrospective study of all cases of tuberculosis of the head and neck region occurring in Bradford, UK. Results: Of a total of 1315 cases of TB, 128 presented with head and neck TB (12 per cent of which (15/128) were in children). Cervical lymph nodes were most commonly involved (87 per cent, 111/128), other sites being: salivary glands (five cases); larynx, oral cavity, eyes and ears (two cases each); and skin, thyroid, nasopharynx and retropharyngeal space (one case each). Patients' ethnic origins were Asian (89 per cent, 114/128), Caucasian (10 per cent, 13/128) and African (one case). Only 26 per cent (33/128) had constitutional symptoms, and 20 per cent (25/128) had a coexistent site of TB. Only 39 per cent (40/105) of surgical specimens were sent for culture. Conclusions: Isolated head and neck TB is not uncommon. Atypical presentations render diagnosis challenging, so awareness aids early diagnosis. Mycobacterial cultures should be performed, where possible, for diagnosis.
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The average duration of symptoms prior to diagnosis of head and neck EPTB can range from 4 weeks to several months, with many patients presenting late due to absence of typical systemic symptoms like coughing or weight loss.
“According to studies as those by Menon et al. [13] and Sharma & Rana [15], the average duration of symptoms prior to diagnosis can range from 4 weeks to several months, with many patients presenting late due to the absence of typical systemic symptoms like coughing or weight loss.”
From Head and Neck Tuberculosis: A Rare Diagnosis and the Role of Surgical Biopsy and Histopathological Evaluation in Extrapulmonary Disease (2025) · cites this paper as Menon et al. [13]
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- Authors
- Menon, K., Bem, C., Gouldesbrough, D., & Strachan, D. R.
- Affiliations
- Bradford Teaching Hospitals NHS Foundation Trust (GB)
- Venue
- The Journal of Laryngology & Otology
- Publisher
- Cambridge University Press (CUP)
- Published
- 2006-08-21
- Volume
- 121
- Issue
- 4
- Pages
- 362-368
- ISSN
- 0022-2151 (ISSN-L)
- 1748-5460
- OpenAlex
- W2170659984
- Cited by
- 95
- References
- 0
- Citations by year
- 2025: 2 · 2024: 5 · 2023: 5 · 2022: 6 · 2021: 7 · 2020: 5 · 2019: 7 · 2018: 13 · 2017: 5 · 2016: 8 · 2015: 5 · 2014: 4 · 2013: 6 · 2012: 1
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Laryngology & Otology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Diagnosis and treatment of tuberculosis
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Surgery › Infectious Diseases and Tuberculosis
- Keywords
- head and neck tuberculosis, scrofula, salivary gland tuberculosis, laryngeal tuberculosis, oral tuberculosis, tuberculosis epidemiology, atypical presentation, mycobacterial culture, ethnicity, children, Bradford
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, England, Female, Humans, Male, Middle Aged, Nasopharynx, Pharyngeal Diseases, Retrospective Studies, Tuberculosis, Tuberculosis, Cutaneous, Tuberculosis, Laryngeal, Tuberculosis, Lymph Node, Tuberculosis, Ocular, Tuberculosis, Oral, Age Distribution, Sex Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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