Cited by 102Child and Adolescent Psychosocial and Emotional DevelopmentGenetic Associations and EpidemiologyAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Monozygotic twins discordant for major depression: a preliminary exploration of the role of environmental experiences in the aetiology and course of illness

KENDLER, KENNETH S., GARDNER, CHARLES O.·2001·Psychological Medicine

DOI 10.1017/s0033291701003622

Open this paper in CoChat — free account

Abstract

Background. Genetic effects upon behaviour are pervasive. To what extent are the many correlates of major depression (MD) due to individual-specific environmental experiences versus genetic factors correlated with risk for MD? Methods. From a population-based twin registry, we identified 72 female monozygotic pairs discordant for a lifetime history of MD and compared the affected and unaffected members on a wide range of putative correlates of MD. Results. The affected twin differed from her unaffected co-twin on many variables, eight of which were maximally discriminating: (i) maternal protectiveness; (ii) conflictual parent–child relationship; (iii) low optimism; (iv) current stressful life events; (v) financial difficulties and a history of (vi) phobia, (vii) nicotine dependence; and (viii) divorce. A cluster analysis suggested three ‘environmental pathways' to MD characterized by: (i) childhood vulnerability and anxiety; (ii) acting-out and demoralization; and (iii) interpersonal difficulties. Conclusion. Important precursors and sequelae of MD originate in environmental experiences unique to the individual and are not mediated through genetic factors or family-of-origin effects. Such environmental factors cause pervasive differences in monozygotic twins discordant for MD, especially in the areas of interpersonal difficulties, psychopathology, social problems and self-concept. These findings should be interpreted in the context of possible retrospective recall bias and the difficulty of distinguishing risk factors from sequelae in co-twin–control studies.

Integrity signals

Registry

Crossref · 10.1017/s0033291701003622

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Society and the Adolescent Self-Image
Rosenberg, M. (1965) · doi:10.1515/9781400876136 · Cited by 30,126
A parental bonding instrument.
Parker, G., Tupling, H., & Brown, L. B. (1979) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1979.tb02487.x · Cited by 3,788
A revised version of the Psychoticism scale
Eysenck, S. B. G., Eysenck, H. J., & Barrett, P. (1985) · Personality and Individual Differences · doi:10.1016/0191-8869(85)90026-1 · Cited by 3,094
Social Origins of Depression: A Study of Psychiatric Disorder in Women.
Schnitzer, P. K., Brown, G. W., & Harris, T. (1980) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2065631 · Cited by 3,053
Measuring nicotine dependence: A review of the Fagerstrom Tolerance Questionnaire
Fagerstrom, K. O., & Schneider, N. G. (1989) · Journal of Behavioral Medicine · doi:10.1007/bf00846549 · Cited by 1,598
The role of parents in the socialization of children: An historical overview.
Maccoby, E. E. (1992) · Developmental Psychology · doi:10.1037/0012-1649.28.6.1006 · Cited by 1,229
The attributional Style Questionnaire
Peterson, C., Semmel, A., von Baeyer, C., Abramson, L., Metalsky, G., & Seligman, M. (1982) · Cognitive Therapy and Research · doi:10.1007/bf01173577 · Cited by 1,226
Smoking and Major Depression: A Causal Analysis
Kendler, K. S. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820130038007 · Cited by 792
Self-citation
The Structure of the Genetic and Environmental Risk Factors for Six Major Psychiatric Disorders in Women
Kendler, K. S. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950170048007 · Cited by 693
Self-citation
Genes, culture, and personality : an empirical approach
Eaves, L. J., Eysenck, H. J., & Martin, N. G. (1989) · Cited by 637

Show all 32 references

Sorted by citations

Effects of perinatal mental disorders on the fetus and child
Stein, A., Pearson, R. M., Goodman, S. H., Rapa, E., Rahman, A., McCallum, M., Howard, L. M., & Pariante, C. M. (2014) · The Lancet · doi:10.1016/s0140-6736(14)61277-0 · Cited by 2,166
The association of cigarette smoking with depression and anxiety: a systematic review
Fluharty, M., Taylor, A. E., Grabski, M., & Munafò, M. R. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntw140 · Cited by 1,299
Gene-Environment Interplay in Relation to Emotional and Behavioral Disturbance
Rutter, M. L., & Silberg, J. L. (2002) · Annual Review of Psychology · doi:10.1146/annurev.psych.53.100901.135223 · Cited by 462
Neural and behavioral substrates of mood and mood regulation
Davidson, R. J., Lewis, D. A., Alloy, L. B., Amaral, D. G., Bush, G., Cohen, J. D., Drevets, W. C., Farah, M. J., Kagan, J., McClelland, J. L., et al. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01458-0 · Cited by 411
Allostasis and the human brain: Integrating models of stress from the social and life sciences.
Ganzel, B. L., Morris, P., & Wethington, E. (2010) · Psychological Review · doi:10.1037/a0017773 · Cited by 415
Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model-Are we there yet?
Jesulola, E., Micalos, P., & Baguley, I. J. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.12.025 · Cited by 379
Maternal Smoking During Pregnancy and Child Outcomes: Real or Spurious Effect?
Knopik, V. S. (2009) · Developmental Neuropsychology · doi:10.1080/87565640802564366 · Cited by 261
The role of the Children of Twins design in elucidating causal relations between parent characteristics and child outcomes
D'Onofrio, B. M., Turkheimer, E. N., Eaves, L. J., Corey, L. A., Berg, K., Solaas, M. H., & Emery, R. E. (2003) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00196 · Cited by 219
Recent developments in understanding the psychosocial aspects of depression
Harris, T. (2001) · British Medical Bulletin · doi:10.1093/bmb/57.1.17 · Cited by 181
Epigenetic mechanisms of major depression: Targeting neuronal plasticity
Uchida, S., Yamagata, H., Seki, T., & Watanabe, Y. (2018) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12621 · Cited by 181
NONSHARED ENVIRONMENTAL INFLUENCES ON ADOLESCENT DELINQUENT INVOLVEMENT AND ADULT CRIMINAL BEHAVIOR*
BEAVER, K. M. (2008) · Criminology · doi:10.1111/j.1745-9125.2008.00112.x · Cited by 158
Omega 3 polyunsaturated fatty acids and the treatment of depression
Deacon, G., Kettle, C., Hayes, D., Dennis, C., & Tucci, J. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2013.876959 · Cited by 149
Poor sleep predicts symptoms of depression and disability retirement due to depression
Paunio, T., Korhonen, T., Hublin, C., Partinen, M., Koskenvuo, K., Koskenvuo, M. J., & Kaprio, J. A. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.10.002 · Cited by 129
TPH2 Gene Polymorphisms and Major Depression – A Meta-Analysis
Gao, J., Pan, Z., Jiao, Z., Li, F., Zhao, G., Wei, Q., Pan, F., & Εvangelou, Ε. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036721 · Cited by 112
Association of smoking and nicotine dependence with severity and course of symptoms in patients with depressive or anxiety disorder
Jamal, M., van der Does, W. A. J., Cuijpers, P. J., & Penninx, B. W. J. H. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.05.001 · Cited by 115
Review: Serotonin by stress interaction: a susceptibility factor for the development of depression?
Firk, C., & Markus, C. R. (2007) · Journal of Psychopharmacology · doi:10.1177/0269881106075588 · Cited by 106
The impact of high neuroticism in parents on children's psychosocial functioning in a population at high risk for major affective disorder: A family–environmental pathway of intergenerational risk
Ellenbogen, M. A., & Hodgins, S. (2004) · Development and Psychopathology · doi:10.1017/s0954579404044438 · Cited by 113
Maternal Depression, Locus of Control, and Emotion Regulatory Strategy as Predictors of Preschoolers’ Internalizing Problems
Coyne, L. W., & Thompson, A. D. (2011) · Journal of Child and Family Studies · doi:10.1007/s10826-011-9455-2 · Cited by 98
Genetics of nicotine dependence and pharmacotherapy
Lessov‐Schlaggar, C. N., Pergadia, M. L., Khroyan, T. V., & Swan, G. E. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.08.018 · Cited by 97
Gene–Environment Interaction in Major Depression and Antidepressant Treatment Response
Keers, R., & Uher, R. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-011-0251-x · Cited by 94
Therapygenetics: Using genetic markers to predict response to psychological treatment for mood and anxiety disorders
Lester, K. J., & Eley, T. C. (2013) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-3-4 · Cited by 95
Risk factors for preschool depression: the mediating role of early stressful life events
Luby, J. L., Belden, A. C., & Spitznagel, E. L. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01672.x · Cited by 91
Demoralization syndrome among cancer outpatients in Taiwan
Lee, C., Fang, C., Yang, Y., Liu, C., Leu, Y., Wang, T.-E., Chang, Y.-F., Hsieh, R.-K., Chen, Y.-J., Tsai, L., et al. (2011) · Supportive Care in Cancer · doi:10.1007/s00520-011-1332-4 · Cited by 84
Is the association of smoking and depression a recent phenomenon?
Johnson, E. O., & Breslau, N. (2006) · Nicotine & Tobacco Research · doi:10.1080/14622200600576644 · Cited by 82
Perceived Work Stress and Major Depressive Episodes in a Population of Employed Canadians Over 18 Years Old
Wang, J. (2004) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000110242.97744.bc · Cited by 81
Children of parents with bipolar disorder
Hodgins, S., Faucher, B., Zarac, A., & Ellenbogen, M. A. (2002) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/s1056-4993(02)00002-0 · Cited by 81
Distress, demoralization and psychopathology: Diagnostic boundaries
de Figueiredo, J. M. (2013) · The European Journal of Psychiatry · doi:10.4321/s0213-61632013000100008 · Cited by 76
Are Stressful Life Events Causally Related to the Severity of Obsessive-Compulsive Symptoms? A Monozygotic Twin Difference Study
Vidal‐Ribas, P., Stringaris, A. K., Rück, C., Serlachius, E., Lichtenstein, P., & Mataix‐Cols, D. (2014) · European Psychiatry · doi:10.1016/j.eurpsy.2014.11.008 · Cited by 67
Marital Dissolution and Blood Pressure Reactivity: Evidence for the Specificity of Emotional Intrusion-Hyperarousal and Task-Rated Emotional Difficulty
Sbarra, D. A., Law, R. W., Lee, L. A., & Mason, A. E. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181a23eee · Cited by 65
Counseling Adopted Persons in Adulthood
Baden, A. L., & Wiley, M. O. (2007) · The Counseling Psychologist · doi:10.1177/0011000006291409 · Cited by 63
A Monozygotic Twin Differences Study of Nonshared Environmental Influence on Adolescent Depressive Symptoms
Liang, H., & Eley, T. C. (2005) · Child Development · doi:10.1111/j.1467-8624.2005.00848.x · Cited by 61
Towards translational rodent models of depression
O’Leary, O. F., & Cryan, J. F. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1587-9 · Cited by 60
Life events and depressiveness – the effect of adjustment for psychosocial factors, somatic health and genetic liability
Romanov, K., Varjonen, J., Kaprio, J. A., & Koskenvuo, M. (2003) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2003.01419.x · Cited by 59
Commentary: Nature–nurture interplay in emotional disorders
Rutter, M. L. (2003) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00178 · Cited by 61
A comparison of early family life events amongst monozygotic twin women with lifetime anorexia nervosa, bulimia nervosa, or major depression
Wade, T. D., Gillespie, N. A., & Martin, N. G. (2007) · International Journal of Eating Disorders · doi:10.1002/eat.20461 · Cited by 57
Adaptation of Lipid Profiling in Depression Disease and Treatment: A Critical Review
Pinto, B., Conde, T., Domingues, I., & Domingues, M. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042032 · Cited by 51
“Thus, it may explain why women’s heritability appears to be much larger than men’s, confirming higher incidence and prevalence of most types of depression in women [40].”
Background
Relationships Among Alexithymia, Adverse Childhood Experiences, Sociodemographic Variables, and Actual Mood Disorder: A 2-Year Clinical Follow-Up Study of Patients With Major Depressive Disorder
Honkalampi, K. M., Koivumaa-Honkanen, H. T., Antikainen, R., Haatainen, K. M., Hintikka, J. J., & Viinamäki, H. T. (2004) · Psychosomatics · doi:10.1176/appi.psy.45.3.197 · Cited by 52
Estimating the Impact of Education on Political Participation: Evidence from Monozygotic Twins in the United States, Denmark and Sweden
Dinesen, P. T., Dawes, C. T., Johannesson, M., Klemmensen, R., Magnusson, P. K. E., Nørgaard, A. S., Petersen, I., & Oskarsson, S. (2016) · Political Behavior · doi:10.1007/s11109-015-9328-2 · Cited by 47
Role of stressful life events and menopausal stage in wellbeing and health
Alexander, J. L., Dennerstein, L., Woods, N. F., McEwen, B. S., Halbreich, U. M., Kotz, K. J., & Richardson, G. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.11s.s93 · Cited by 48
Depression and HIV Risk Behavior Practices Among “At Risk” Women
Klein, H., Elifson, K. W., & Sterk, C. E. (2008) · Women & Health · doi:10.1080/03630240802313605 · Cited by 43
Greater Physiological and Behavioral Effects of Interrupted Stress Pattern Compared to Daily Restraint Stress in Rats
Zhang, W., Hetzel, A., Shah, B., Atchley, D., Blume, S. R., Padival, M., & Rosenkranz, J. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102247 · Cited by 44
Executive Self, Self-Esteem, and Negative Affectivity: Relations at the Phenotypic and Genotypic Level.
Neiss, M. B., Stevenson, J., Sedikides, C., Kumashiro, M., Finkel, E. J., & Rusbult, C. E. (2005) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.89.4.593 · Cited by 43
The road not taken: life experiences in monozygotic twin pairs discordant for major depression
Kendler, K. S., & Halberstadt, L. J. (2012) · Molecular Psychiatry · doi:10.1038/mp.2012.55 · Cited by 41
Self-citation
Associations between substance use disorders and major depression in parents and late adolescent–emerging adult offspring: an adoption study
Marmorstein, N. R., Iacono, W. G., & McGue, M. K. (2012) · Addiction · doi:10.1111/j.1360-0443.2012.03934.x · Cited by 45
A Population Based Twin Study of Sex Differences in Depressive Symptoms
Arpana Agrawal, A., Jacobson, K. C., Gardner, C. O., Prescott, C. A., & Kendler, K. S. (2004) · Twin Research · doi:10.1375/136905204323016159 · Cited by 42
Self-citation
Genetic and environmental risk factors for depression assessed by subject-rated Symptom Check List versus Structured Clinical Interview
Foley, D. L., Neale, M. C., & Kendler, K. S. (2001) · Psychological Medicine · doi:10.1017/s0033291701004755 · Cited by 37
Self-citation
Prevention of anxiety disorders: A model for intervention
Craske, M. G., & Zucker, B. G. (2001) · Applied and Preventive Psychology · doi:10.1016/s0962-1849(01)80012-3 · Cited by 37
Stressful life events increase the risk of major depressive episodes: A population-based twin study
Bjørndal, L. D., Kendler, K. S., Reichborn-Kjennerud, T., & Ystrom, E. (2023) · Psychological Medicine · doi:10.1017/s0033291722002227 · Cited by 35
“…on the risk of depression has been suggested for a number of specific SLEs included in the current study, such as assault (Kendler et al., 1999a, 2010), sexual abuse (Kendler et al., 2000; Kendler & Aggen, 2014; Nelson et al., 2002), and romantic problems and job loss (Kendler & Gardner, 2001).”
BackgroundMethodResultInfluentialSelf-citation
Psychological well-being (PWB): a natural life outlook? An Italian twin study on heritability of PWB in young adults
Gigantesco, A., Stazi, M. A., Alessandri, G., Medda, E., Tarolla, E., & Fagnani, C. (2011) · Psychological Medicine · doi:10.1017/s0033291711000663 · Cited by 41
Development and psychopathology: a life course perspective
Maughan, B., & Collishaw, S. (2015) · Rutter's Child and Adolescent Psychiatry · doi:10.1002/9781118381953.ch1 · Cited by 31
Performance of Polygenic Scores for Predicting Phobic Anxiety
Walter, S., Glymour, M. M., Koenen, K. C., Liang, L., Tchetgen, E. J. T., Cornelis, M. C., Chang, S.-C., Rimm, E. B., Kawachi, I. I., & Kubzansky, L. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080326 · Cited by 28
The influence of life events on first and recurrent admissions in bipolar disorder
Kemner, S. M., van Haren, N. E. M., Bootsman, F., Eijkemans, M. J. C., Vonk, R., van der Schot, A. C., Nolen, W. A., & Hillegers, M. H. J. (2015) · International Journal of Bipolar Disorders · doi:10.1186/s40345-015-0022-4 · Cited by 27
Sex-Specific Association of Depression and a Haplotype in Leukotriene A4 Hydrolase Gene
Zhao, J., Quyyumi, A. A., Patel, R. S., Zafari, A. M., Veledar, E., Onufrak, S. J., Shallenberger, L. H., Jones, L. R., & Vaccarino, V. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181b05c57 · Cited by 24
Life events: effects and genesis
Paykel, E. S. (2003) · Psychological Medicine · doi:10.1017/s0033291703008638 · Cited by 25
The associations of birth outcome differences in twins with prenatal exposure to bisphenol A and its alternatives
Wang, J., Mei, H., Zhou, A., Huang, L.-L., Cao, Z., Hong, A.-B., Yang, M., Xie, Q., Chen, D., Yang, S., et al. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111459 · Cited by 22
Adolescent twins discordant for major depressive disorder: shared familial liability to externalizing and other internalizing disorders
Burcusa, S. L., Iacono, W. G., & McGue, M. K. (2003) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00184 · Cited by 22
Association of the T102C polymorphism in the HTR2A gene with major depressive disorder, bipolar disorder, and schizophrenia
Tan, J., Chen, S., Su, L., Long, J., Xie, J., Shen, T., Jiang, J., & Gu, L. (2014) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32248 · Cited by 21
Genetic and Environmental Contributions of Negative Valence Systems to Internalizing Pathways
Cecilione, J. L., Rappaport, L. M., Hahn, S., Anderson, A. E., Hazlett, L. E., Burchett, J. R., Moore, A. A., Savage, J. E., Hettema, J. M., & Roberson‐Nay, R. (2018) · Twin Research and Human Genetics · doi:10.1017/thg.2017.72 · Cited by 19
Nonshared Environmental Effects on Adulthood Psychopathic Personality Traits: Results from a Monozygotic Twin Difference Scores Analysis
Beaver, K. M., Vaughn, M. G., & DeLisi, M. (2013) · Psychiatric Quarterly · doi:10.1007/s11126-013-9255-5 · Cited by 19
Demoralisation - A Useful Conceptualisation of Non-Specific Psychological Distress Among Refugees Attending Mental Health Services
Briggs, L., & Macleod, A. D. (2006) · International Journal of Social Psychiatry · doi:10.1177/0020764006066832 · Cited by 19
Depression and psychological distress: a life course perspective
Maughan, B., & Rodgers, B. (2002) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780192632890.003.0008 · Cited by 19
Neuropsychological deficits in major depression reflect genetic/familial risk more than clinical history: A monozygotic discordant twin-pair study
Hsu, K. J., Young‐Wolff, K. C., Kendler, K. S., Halberstadt, L. J., & Prescott, C. A. (2013) · Psychiatry Research · doi:10.1016/j.psychres.2013.10.037 · Cited by 17
Self-citation
Exposure to per- and polyfluoroalkyl substances in women with twin pregnancies: Patterns and variability, transplacental transfer, and predictors
Huang, S., Li, X., Deng, L., Xie, J., Huang, G., Zeng, C., Wu, N.-X., Zhu, S., Liu, C., Mei, H., et al. (2023) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2023.132432 · Cited by 17
Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms
Gonda, X., Eszlári, N., Kovács, D., Anderson, I. M., Deakin, J. F. W., Juhász, G., & Bagdy, G. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.57 · Cited by 17
Meta-analysis of association between TPH2 single nucleotide poiymorphism and depression
Liu, Z.-L., Wang, X., Liu, M., & Ye, B. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.104517 · Cited by 18
Testosterone Replacement Therapy in the Treatment of Depression
Anderson, D. J., Vazirnia, P., Loehr, C. A., Sternfels, W., Hasoon, J. J., Viswanath, O., Kaye, A. D., & Urits, I. (2022) · Health Psychology Research · doi:10.52965/001c.38956 · Cited by 18
P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms
Kristóf, Z., Eszlári, N., Sütöri, S., Gál, Z., Török, D., Baksa, D., Petschner, P., Sperlágh, B., Anderson, I. M., Deakin, J. F. W., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0252766 · Cited by 16
Differences in frontal and limbic brain activation in a small sample of monozygotic twin pairs discordant for severe stressful life events
Godinez, D. A., McRae, K., Andrews‐Hanna, J. R., Smolker, H. R., & Banich, M. T. (2016) · Neurobiology of Stress · doi:10.1016/j.ynstr.2016.10.002 · Cited by 15
Do depressive episodes lead to accumulation of vulnerability in the elderly?
Oldehinkel, A. J., van den Berg, M. D., Bouhuys, A. L., & Ormel, J. (2003) · Depression and Anxiety · doi:10.1002/da.10116 · Cited by 14
Nicotine Addiction: Past and Present
Office on Smoking (2010) · Cited by 14
The Influence of Psychopathic Personality Traits, Low Self-Control, and Nonshared Environmental Factors on Criminal Involvement
Boccio, C. M., & Beaver, K. M. (2016) · Youth Violence and Juvenile Justice · doi:10.1177/1541204016684176 · Cited by 13
Mood Disorders and Symptoms in Girls
Zahn‐Waxler, C., Race, E., & Duggal, S. (2005) · Springer eBooks · doi:10.1007/0-306-48674-1_2 · Cited by 11
[Children of parents with bipolar disorder].
Reichart, C. G., Wals, M., & Hillegers, M. H. J. (2007) · PubMed · Cited by 11
Demoralization Revisited
Shader, R. I. (2005) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000172072.58388.74 · Cited by 11
Genetic and environmental influences on global family conflict.
Horwitz, B. N., Neiderhiser, J. M., Ganiban, J. M., Spotts, E. L., Lichtenstein, P., & Reiss, D. (2010) · Journal of Family Psychology · doi:10.1037/a0019064 · Cited by 9
Gene—environment interplay in relation to emotional and behavioural disturbance
Rutter, M. L. (2002) · European Psychiatry · doi:10.1016/s0924-9338(02)80062-1 · Cited by 9
Perinatal mental health 3 Eff ects of perinatal mental disorders on the fetus and child
Stein, A. L., Pearson, R. M., Goodman, S. H., Rapa, E., Rahman, A., McCallum, M., Howard, L. M., & Pariante, C. M. (2014) · Cited by 7
Phenotypic and Discordant-Monozygotic Analyses of Stress and Perceived Social Support as Antecedents to or Sequelae of Risk for Depression
Coventry, W. L., Medland, S. E., Wray, N. R., Thorsteinsson, E., Heath, A. C., & Byrne, B. (2009) · Twin Research and Human Genetics · doi:10.1375/twin.12.5.469 · Cited by 7
The Effects of Nonshared Environments on Adolescent Depression: Findings From a Sample of Monozygotic Twins
Shields, R. T., & Beaver, K. M. (2010) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2010.08.022 · Cited by 5
Ideas equivocadas sobre la depresión y su tratamiento (I)
Sanz, J., & García‐Vera, M. P. (2017) · Papeles del Psicólogo - Psychologist Papers · doi:10.23923/pap.psicol2017.2833 · Cited by 5
Genetic foundations of vulnerability to depression
Fañanás, L. (2009) · Anales del Sistema Sanitario de Navarra · doi:10.23938/assn.0840 · Cited by 4
Evidence that stress per se has a role in the precipitation and natural history of depressive illness
Gold, P. W. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.85 · Cited by 4
Mood Instability Is a Precursor of Relationship and Marital Difficulties: Results from Prospective Data from the British Health and Lifestyle Surveys
Bowen, R., Dong, L. Y., Peters, E. M., Baetz, M., & Balbuena, L. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00276 · Cited by 3
Affektive Störungen — Neuropsychologie
Hautzinger, M. (2006) · Springer eBooks · doi:10.1007/3-540-30887-3_10 · Cited by 3
The Dark Side of Divorce
Sbarra, D. A., & Mason, A. E. (2013) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780195398700.013.0008 · Cited by 3
Depression
Craig, T. (2010) · Wiley eBooks · doi:10.1002/9780470684214.ch16 · Cited by 3
Mental illbeing and wellbeing are influenced by recent adverse life events. Evidence from a longitudinal twin study
Hofgaard, L. S., Nes, R. B., Vassend, O. M., Ayorech, Z., Czajkowski, N. O., & Røysamb, E. (2025) · Current Psychology · doi:10.1007/s12144-025-07758-3 · Cited by 2
Monozygotic twins discordant for depression: An extended network comparison of depressive symptoms, cognitive functions and daily activities
Moroń, M., Mengel‐From, J., & Semkovska, M. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.07.037 · Cited by 3
IGF-I, IGF-BP3, and GH serum levels after stimulation tests in prepubertal allergic boys.
Hauache, A. G., Spinola‐Castro, A. M., Lourenzi, V., Tufík, S., Naspitz, C. K., & Solé, D. (2003) · PubMed · Cited by 2
Genetic epidemiology in a molecular age
Paykel, E. S. (2002) · Psychological Medicine · doi:10.1017/s0033291702006542 · Cited by 2
Twin and Genetic Effects on Life Events
Middeldorp, C. M., Cath, D. C., Vink, J. M., & Boomsma, D. I. (2005) · Twin Research and Human Genetics · doi:10.1375/1832427054253130 · Cited by 35
Eating Pathology and Perceptions of the Parent-Child Relationship across Adolescence: Exploring Longitudinal Associations within a Monozygotic Twin Differences Design
Wallace, L. M. (2015) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/25777 · Cited by 1
At risk for depression : the role of stress and serotonergic vulnerability
Firk, C. (2009) · Research Publications (Maastricht University) · doi:10.26481/dis.20090312cf
Genetics of Mood Disorders: Current Status of Knowledge and Prospects 1
Maier, W. (2002) · KARGER eBooks · doi:10.1159/000066875
Análisis de registros MEG en pacientes con depresión
Gómez, R., & José, S. (2014) · University of Valladolid Documentary Repository (University of Valladolid)
Heritability and Differential Susceptibility (to Mental Disorders)
Bannon, B. L., Zavala, C., Horwitz, B. N., & Reynolds, C. A. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-397045-9.00255-x
Research Counseling Adopted Persons in Adulthood: Integrating Practice and
Baden, A. L., & Wiley, M. O. (2014)
Structural brain imaging and cognitive function in individuals at high familial risk of mood disorders
Papmeyer, M. (2015) · ERA
Avaliação da resposta terapêutica de pacientes depressivos com estresse precoce: uma perspectiva da terapia ocupacional
Monteverde, C. M. S. M. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2017.tde-05012017-113410
Depresijas un ģeneralizētas trauksmes traucējumu simptomu izplatība un dzimuma specifiskie asociētie faktori Latvijas vispārējā pieaugušo iedzīvotāju populācijā. Promocijas darbs
Vinogradova, V. V. (2023) · doi:10.25143/prom-rsu_2023-17_pd

Authors: KENDLER, K. S., & GARDNER, C. O.
Affiliations: Virginia Commonwealth University (US)
ORCID: KENDLER, KENNETH S.
Venue: Psychological Medicine
Publisher: Cambridge University Press (CUP)
Published: 2001-04
Volume: 31
Issue: 3
Pages: 411-423
ISSN: 0033-2917 (ISSN-L)
1469-8978
DOI: 10.1017/s0033291701003622
OpenAlex: W2132589140
Cited by: 102
References: 32
Citations by year: 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 3 · 2018: 1 · 2017: 5 · 2016: 6 · 2015: 6 · 2014: 8 · 2013: 8 · 2012: 4
FWCI: 9.32
Type: journal article
Language: en
Open access: closed
Licence: www.cambridge.org/core/terms (unspecified, 11 d)
Locations: Psychological Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k05mh001277-05)
National Institute on Alcohol Abuse and Alcoholism (R01AA009095, AA-09095)
National Institute of Mental Health (MH-01277, R01MH040828, MH 40828)
Topics: Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: major depressive disorder, monozygotic twins, discordant twins, environmental risk factors, parent-child conflict, optimism, life events, financial hardship, phobia, nicotine dependence, divorce, childhood anxiety, interpersonal problems, etiology of depression, genetic versus environmental factors, co-twin control
MeSH terms: Adult, Alcohol Drinking, Major Depressive Disorder, Environment, Female, Health Status, Humans, Parent-Child Relations, Personality, Psychiatric Status Rating Scales, Risk Factors, Self Concept, Severity of Illness Index, Twins, Monozygotic, Cluster Analysis, Marital Status, Substance-Related Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Monozygotic twins discordant for major depression: a preliminary exploration of the role of environmental experiences in the aetiology and course of illness

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks