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. Psychological treatments in schizophrenia: I. meta-analysis of family intervention and cognitive behaviour therapy.
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Background. While there is a growing body of evidence on the efficacy of psychological interventions for schizophrenia, this meta-analysis improves upon previous systematic and meta-analytical reviews by including a wider range of randomized controlled trials and providing comparisons against both standard care and other active interventions. Method. Literature searches identified randomized controlled trials of four types of psychological interventions: family intervention, cognitive behavioural therapy (CBT), social skills training and cognitive remediation. These were then subjected to meta-analysis on a variety of outcome measures. This paper presents results relating to the first two. Results. Family therapy, in particular single family therapy, had clear preventative effects on the outcomes of psychotic relapse and readmission, in addition to benefits in medication compliance. CBT produced higher rates of ‘important improvement’ in mental state and demonstrated positive effects on continuous measures of mental state at follow-up. CBT also seems to be associated with low drop-out rates. Conclusions. Family intervention should be offered to people with schizophrenia who are in contact with carers. CBT may be useful for those with treatment resistant symptoms. Both treatments, in particular CBT, should be further investigated in large trials across a variety of patients, in various settings. The factors mediating treatment success in these interventions should be researched.
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“These findings are consistent with previous studies of acceptance and commitment therapy for psychosis.”
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“A recent meta-analysis of mindfulness/acceptance interventions for psychosis showed that these treatments are most effective for distress related to psychosis and negative or affective symptoms.60,61”
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Metadata
- Authors
- PILLING, S., BEBBINGTON, P., KUIPERS, E., GARETY, P., GEDDES, J., ORBACH, G., & MORGAN, C.
- Affiliations
- St Thomas' Hospital (GB)
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2002-07
- Volume
- 32
- Issue
- 5
- Pages
- 763-782
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2160436994
- Cited by
- 887
- References
- 62
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 8 · 2023: 13 · 2022: 10 · 2021: 52 · 2020: 29 · 2019: 24 · 2018: 17 · 2017: 20 · 2016: 32 · 2015: 25 · 2014: 37 · 2013: 41 · 2012: 55
- FWCI
- 8.31
- Type
- journal article
- Language
- en
- Open access
- green
- discovery.ucl.ac.uk
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Counseling, Therapy, and Family Dynamics
- Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
- Keywords
- schizophrenia, family intervention, family therapy, cognitive behavioral therapy, social skills training, cognitive remediation, psychotic relapse, hospital readmission, medication adherence, treatment discontinuation, caregivers, treatment-resistant symptoms
- MeSH terms
- Adolescent, Adult, Family Therapy, Humans, Male, Middle Aged, Outcome and Process Assessment, Health Care, Schizophrenia, Schizophrenic Psychology, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic
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