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. Psychological treatments in schizophrenia: I. meta-analysis of family intervention and cognitive behaviour therapy.
Open accessAbstract
Background. While there is a growing body of evidence on the efficacy of psychological interventions for schizophrenia, this meta-analysis improves upon previous systematic and meta-analytical reviews by including a wider range of randomized controlled trials and providing comparisons against both standard care and other active interventions. Method. Literature searches identified randomized controlled trials of four types of psychological interventions: family intervention, cognitive behavioural therapy (CBT), social skills training and cognitive remediation. These were then subjected to meta-analysis on a variety of outcome measures. This paper presents results relating to the first two. Results. Family therapy, in particular single family therapy, had clear preventative effects on the outcomes of psychotic relapse and readmission, in addition to benefits in medication compliance. CBT produced higher rates of ‘important improvement’ in mental state and demonstrated positive effects on continuous measures of mental state at follow-up. CBT also seems to be associated with low drop-out rates. Conclusions. Family intervention should be offered to people with schizophrenia who are in contact with carers. CBT may be useful for those with treatment resistant symptoms. Both treatments, in particular CBT, should be further investigated in large trials across a variety of patients, in various settings. The factors mediating treatment success in these interventions should be researched.
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“These findings are consistent with previous studies of acceptance and commitment therapy for psychosis.”
From Acceptance-based Behavior Therapy for Depression With Psychosis (2015) · cites this paper as [60]
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“A recent meta-analysis of mindfulness/acceptance interventions for psychosis showed that these treatments are most effective for distress related to psychosis and negative or affective symptoms.60,61”
From Acceptance-based Behavior Therapy for Depression With Psychosis (2015) · cites this paper as [60]
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“Psychosocial interventions to enhance coping ability and social support can reduce symptom severity and improve overall level of functioning (Pilling et al., 2002).”
BackgroundAbbs, B., Achalia, R. M., Adelufosi, A. O., Aktener, A. Y., Beveridge, N. J., Bhakta, S. G., Blackman, R. K., Bora, E., Byun, M. S., Cabanis, M., et al. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.07.024 · Cited by 8
Recovery from a psychiatrist's viewpoint.
Diamond, R. J. (2006) · PubMed · Cited by 10
Bredemeier, K., Beck, A. T., & Grant, P. M. (2017) · Clinical Psychological Science · doi:10.1177/2167702617734019 · Cited by 9
“Despite the historical emphasis on biological theories, research, and treatment in schizophrenia, psychosocial treatments have proven quite efficacious in promoting recovery in this population (Dixon et al., 2010; Kern, Glynn, Horan, & Marder, 2009; National Institute for Health and Clinical Excellence, 2002; Pilling…”
BackgroundPsychosoziale Interventionen bei schweren psychischen Störungen
Riedel-Heller, S. G., Gühne, U., Weinmann, S., Arnold, K., Ay, E., & Becker, T. (2012) · Der Nervenarzt · doi:10.1007/s00115-011-3471-8 · Cited by 9
Mayoral, F., Berrozpe, A., Romero, J. D. L. H., Jambrina, J. J. M., Luna, J. D. D., & Torres‐González, F. (2014) · Revista de Psiquiatría y Salud Mental · doi:10.1016/j.rpsm.2013.11.001 · Cited by 9
Management of early-onset psychosis
Shaw, M., & Singh, S. P. (2004) · Current Opinion in Psychiatry · doi:10.1097/01.yco.0000133826.11672.0b · Cited by 9
What is it like to be friends with a young person with psychosis? A qualitative study
Brand, R. M., Harrop, C. E., & Ellett, L. (2010) · Psychosis · doi:10.1080/17522439.2010.528562 · Cited by 9
“In the same way that family interventions have been shown to be effective (Pilling et al., 2002), peer interventions offer the potential to intervene in what might be considered to be a more important area during this developmental phase.”
BackgroundCaqueo‐Urízar, A., Gutiérrez‐Maldonado, J., & Palma-Faúndez, C. (2011) · Procedia - Social and Behavioral Sciences · doi:10.1016/j.sbspro.2011.10.482 · Cited by 9
Wessels, H., Wagner, M., Kuhr, K., Berning, J., Pützfeld, V., Janssen, B., Bottlender, R., Maurer, K., Möller, H., Gaebel, W., et al. (2019) · Early Intervention in Psychiatry · doi:10.1111/eip.12460 · Cited by 9
Dyck, D. G., Weeks, D. L., Smith, C. L., & Shaw, M. R. (2020) · Journal of Spinal Cord Medicine · doi:10.1080/10790268.2019.1710946 · Cited by 9
Psychotherapie der Schizophrenie
Klingberg, S., Roesch-Ely, D., Buchkremer, G., & Mundt, C. (2008) · Elsevier eBooks · doi:10.1016/b978-343723730-0.50023-9 · Cited by 9
Mechanisms of disrupted language comprehension in schizophrenia
Condray, R., & Steinhauer, S. R. (2003) · Behavioral and Brain Sciences · doi:10.1017/s0140525x03270023 · Cited by 9
Psychological and social interventions for schizophrenia
Kingdon, D. (2006) · BMJ · doi:10.1136/bmj.333.7561.212 · Cited by 9
“Working with families to improve coping and reduce high expressed emotion is already well established as a means to reduce relapse rates in schizophrenia.”
BackgroundO’Connor, C., & Vaughan, S. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.113726 · Cited by 8
“While the various treatment approaches can be complementary, their relative efficacy varies across diagnoses and patient characteristics (Bandelow et al., 2007; Cuijpers et al., 2013; Pilling et al., 2002).”
BackgroundFamily-based interventions versus standard care for people with schizophrenia
Chien, W. T., Ma, C. F., Bressington, D. T., & Suen, L. K. P. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013541 · Cited by 8
Psychoedukation bei Personen mit erhöhtem Psychoserisiko
Zarafonitis, S., Wagner, M., Pützfeld, V., Berning, J., Janssen, B., Decker, P., Ronald Bottlender, A., Möller, H., Gäebel, W., Maier, W., et al. (2012) · Psychotherapeut · doi:10.1007/s00278-012-0928-6 · Cited by 8
Gamble, C., Sin, J., Kelly, M., O'Loughlin, D., & Moone, N. (2012) · Journal of Psychiatric and Mental Health Nursing · doi:10.1111/jpm.12013 · Cited by 8
Fleming, M. P., & Martin, C. R. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-012-0260-4 · Cited by 8
Lecomte, T., Corbière, M., & Leclerc, C. (2014) · The Canadian Journal of Psychiatry · doi:10.1177/070674371405900404 · Cited by 8
Metadata
- Authors
- PILLING, S., BEBBINGTON, P., KUIPERS, E., GARETY, P., GEDDES, J., ORBACH, G., & MORGAN, C.
- Affiliations
- St Thomas' Hospital (GB)
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2002-07
- Volume
- 32
- Issue
- 5
- Pages
- 763-782
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2160436994
- Cited by
- 887
- References
- 62
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 8 · 2023: 13 · 2022: 10 · 2021: 52 · 2020: 29 · 2019: 24 · 2018: 17 · 2017: 20 · 2016: 32 · 2015: 25 · 2014: 37 · 2013: 41 · 2012: 55
- FWCI
- 8.31
- Type
- journal article
- Language
- en
- Open access
- green
- discovery.ucl.ac.uk
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Counseling, Therapy, and Family Dynamics
- Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
- Keywords
- schizophrenia, family intervention, family therapy, cognitive behavioral therapy, social skills training, cognitive remediation, psychotic relapse, hospital readmission, medication adherence, treatment discontinuation, caregivers, treatment-resistant symptoms
- MeSH terms
- Adolescent, Adult, Family Therapy, Humans, Male, Middle Aged, Outcome and Process Assessment, Health Care, Schizophrenia, Schizophrenic Psychology, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic
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