Bright light therapy for agitation in dementia: a randomized controlled trial
Open accessAbstract
BACKGROUND: Agitation is common in people with dementia, is distressing to patients and stressful to their carers. Drugs used to treat the condition have the potential to cause particularly severe side effects in older people with dementia and have been associated with an increased death rate. Alternatives to drug treatment for agitation should be sought. The study aimed to assess the effects of bright light therapy on agitation and sleep in people with dementia. METHODS: A single center randomized controlled trial of bright light therapy versus standard light was carried out. The study was completed prior to the mandatory registration of randomized controls on the clinical trials registry database and, owing to delays in writing up, retrospective registration was not completed. RESULTS: There was limited evidence of reduction in agitation in people on active treatment, sleep was improved and a suggestion of greater efficacy in the winter months. CONCLUSIONS: Bright light therapy is a potential alternative to drug treatment in people with dementia who are agitated.
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A recent meta-analysis of family caregiver interventions for overall neuropsychiatric symptoms in dementia found an effect size of 0.23, but did not consider which symptoms improved.
“A recent meta-analysis of family caregiver interventions for overall neuropsychiatric symptoms in dementia found an effect size of 0.23, but did not consider which symptoms improved. 8”
From Non-pharmacological interventions for agitation in dementia: systematic review of randomised controlled trials (2014) · cites this paper as [8]
Sleep quality was particularly improved in 48 patients with dementia receiving bright light therapy.
“found that sleep quality was particularly improved in 48 patients with dementia.”
From Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review (2015) · cites this paper as [29]
Agitation improved but there was no statistically significant effect of bright light therapy on agitation.
“Agitation improved but there was no statistically significant effect.”
From Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review (2015) · cites this paper as [29]
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- Authors
- Burns, A., Allen, H., Tomenson, B., Duignan, D., & Byrne, J.
- Affiliations
- University of Manchester (GB)
- Manchester Mental Health and Social Care Trust (GB)
- Corresponding author
- Burns, Alistair
- Venue
- International Psychogeriatrics
- Publisher
- Elsevier BV
- Published
- 2009-08
- Volume
- 21
- Issue
- 4
- Pages
- 711-721
- ISSN
- 1041-6102 (ISSN-L)
- OpenAlex
- W2105948530
- Cited by
- 171
- References
- 41
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 13 · 2023: 12 · 2022: 12 · 2021: 12 · 2020: 11 · 2019: 16 · 2018: 8 · 2017: 12 · 2016: 11 · 2015: 3 · 2014: 14 · 2013: 10 · 2012: 5
- FWCI
- 4.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Psychogeriatrics (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Funders
- Ministry of Earth Sciences
- Ministry of Education, India
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Keywords
- bright light therapy, dementia, agitation, sleep, non-pharmacological treatment, seasonal variation, winter, carer stress
- MeSH terms
- Activities of Daily Living, Aged, Aged, 80 and over, Alzheimer Disease, Depressive Disorder, Female, Homes for the Aged, Humans, Sleep Initiation and Maintenance Disorders, Male, Mental Status Schedule, Nursing Homes, Phototherapy, Psychomotor Agitation, Seasons, Dementia, Vascular, Lewy Body Disease
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