The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Mild Cognitive Impairment:An Overview
Abstract
Mild cognitive impairment (MCI) refers to the transitional state between the cognitive changes of normal aging and very early dementia. MCI has generated a great deal of research from both clinical and research perspectives. Several population- and community-based studies have documented an accelerated rate of progression to dementia and Alzheimer's disease in individuals diagnosed with MCI. Clinical subtypes of MCI have been proposed to broaden the concept and include prodromal forms of a variety of dementias. An algorithm is presented to assist the clinician in identifying subjects and subclassifying them into the various types of MCI. Progression factors, including genetic, neuroimaging, biomarker, and clinical characteristics, are discussed. Neuropathological studies indicating an intermediate state between normal aging and early dementia in subjects with MCI are presented. The recently completed clinical trials as well as neuropsychological and nutritional interventions are discussed. Finally, the clinical utility of MCI, and directions for future research are proposed.
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Citations
Cites
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Mild Cognitive Impairment: Clinical Characterization and Outcome
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Self-citationMild cognitive impairment as a diagnostic entity
Petersen, R. C. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01388.x · Cited by 7,864
Self-citationThe Global Deterioration Scale for assessment of primary degenerative dementia
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Self-citationImaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B
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Self-citationMild Cognitive Impairment Represents Early-Stage Alzheimer Disease
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Cited by
Single subject prediction of brain disorders in neuroimaging: Promises and pitfalls
Arbabshirani, M. R., Plis, S., Sui, J., & Calhoun, V. D. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2016.02.079 · Cited by 912
Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship
Nelson, P. T., Braak, H., & Markesbery, W. R. (2009) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181919a48 · Cited by 643
Probing the biology of Alzheimer’s disease in mice
Ashe, K. H., & Zahs, K. R. (2010) · Neuron · doi:10.1016/j.neuron.2010.04.031 · Cited by 413
Changing perspectives regarding late-life dementia
Fotuhi, M., Hachinski, V., & Whitehouse, P. J. (2009) · Nature Reviews Neurology · doi:10.1038/nrneurol.2009.175 · Cited by 291
Episodic simulation of future events is impaired in mild Alzheimer's disease
Addis, D. R., Sacchetti, D. C., Ally, B. A., Budson, A. E., & Schacter, D. L. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.05.018 · Cited by 287
Metadata
- Authors
- Petersen, R. C., & Negash, S.
- Venue
- CNS Spectrums
- Publisher
- Cambridge University Press (CUP)
- Published
- 2008-01
- Volume
- 13
- Issue
- 1
- Pages
- 45-53
- ISSN
- 1092-8529 (ISSN-L)
- 2165-6509
- OpenAlex
- W2117873449
- Cited by
- 667
- References
- 54
- FWCI
- 27.79
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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