The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A Microfabrication-Based Dynamic Array Cytometer
Abstract
We have developed a microfabricated device for use in parallel luminescent single-cell assays that can sort populations upon the basis of dynamic functional responses to stimuli. This device is composed of a regular array of noncontact single-cell traps. These traps use dielectrophoresis to stably confine cells and hold them against disrupting fluid flows. Using quantitative modeling, we have designed traps with a novel asymmetric extruded-quadrupole geometry. This new trap can be physically arrayed and electrically addressed, enabling our cytometer. Situating an array of these traps in a microchannel, we have introduced cells into the array and demonstrated observation of fluorescent dynamic responses followed by sorting. Such a device has potential for use in investigating functional processes, as revealed by temporal behavior, in large numbers of single cells.
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Cites
Inositol trisphosphate and calcium signalling
Berridge, M. J. (1993) · Nature · doi:10.1038/361315a0 · Cited by 6,545
Jones, T. B. (1995) · doi:10.1017/cbo9780511574498 · Cited by 2,786
A N EW A PPROACH TO D ECODING L IFE : Systems Biology
Ideker, T., Galitski, T., & Hood, L. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.343 · Cited by 1,664
Cited by
El-Ali, J., Sorger, P. K., & Jensen, K. F. (2006) · Nature · doi:10.1038/nature05063 · Cited by 2,102
ELECTRICAL FORCES FOR MICROSCALE CELL MANIPULATION
Voldman, J. (2006) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.8.061505.095739 · Cited by 892
Self-citationMicrofluidics for cell separation
Bhagat, A. A. S., Bow, H., Hou, H. W., Tan, S. J., Han, J., & Lim, C. T. (2010) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-010-0611-4 · Cited by 632
Toner, M., & Irimia, D. (2005) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.7.011205.135108 · Cited by 623
Self-citationMicrofluidics technology for manipulation and analysis of biological cells
Yi, C., Li, C.-W., Ji, S., & Yang, M. (2006) · Analytica Chimica Acta · doi:10.1016/j.aca.2005.12.037 · Cited by 478
Metadata
- Authors
- Voldman, J., Gray, M. L., Toner, M., & Schmidt, M. A.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-07-10
- Volume
- 74
- Issue
- 16
- Pages
- 3984-3990
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W1993390786
- Cited by
- 328
- References
- 3
- FWCI
- 12.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- Voldman, J., Gray, M. L., Toner, M., & Schmidt, M. A. (2002). A Microfabrication-Based Dynamic Array Cytometer. Analytical Chemistry. https://doi.org/10.1021/ac0256235
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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