The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Dopamine-,l-DOPA-, Adrenaline-, and Noradrenaline-Induced Growth of Au Nanoparticles: Assays for the Detection of Neurotransmitters and of Tyrosinase Activity
Abstract
The neurotransmitters dopamine (1), L-DOPA (2), adrenaline (3), and noradrenaline (4) mediate the generation and growth of Au nanoparticles (Au-NPs). The plasmon absorbance of the Au-NPs allows the quantitative colorimetric detection of the neurotransmitters. Neurotransmitters 1, 2, and 4 are sensed with a detection limit of 2.5 x 10(-6) M, whereas the detection limit for analyzing 3 corresponds to 2 x 10(-5) M. The neurotransmitter-mediated growth of the Au-NPs is also used to probe the activity of tyrosinase. The later biocatalyst oxidizes tyrosine to L-DOPA that mediates the growth of the Au-NPs. The analysis of tyrosinase activity is important for detecting melanoma cells and Parkinson disease.
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"Plugging into Enzymes": Nanowiring of Redox Enzymes by a Gold Nanoparticle
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Metadata
- Authors
- Baron, R., Zayats, M., & Willner, I.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-02-04
- Volume
- 77
- Issue
- 6
- Pages
- 1566-1571
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2091856513
- Cited by
- 373
- References
- 13
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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