The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Million-fold Preconcentration of Proteins and Peptides by Nanofluidic Filter
Abstract
We have developed a highly efficient microfluidic sample preconcentration device based on the electrokinetic trapping mechanism enabled by nanofluidic filters. The device, fabricated by standard photolithography and etching techniques, generates an extended space charge region within a microchannel, which was used to both collect and trap the molecules efficiently. The electrokinetic trapping and collection can be maintained for several hours, and concentration factors as high as 10(6)-10(8) have been demonstrated. This device could be useful in various bioanalysis microsystems, due to its simplicity, performance, robustness, and integrabilty to other separation and detection systems.
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Cites
Increased Vascularization in Mice Overexpressing Angiopoietin-1
Suri, C., McClain, J., Thurston, G., McDonald, D. M., Zhou, H., Oldmixon, E. H., Sato, T. N., & Yancopoulos, G. D. (1998) · Science · doi:10.1126/science.282.5388.468 · Cited by 818
Cited by
Concentration Polarization and Nonlinear Electrokinetic Flow near a Nanofluidic Channel
Kim, S. J., Wang, Y.-C., Lee, J. H., Jang, H., & Han, J. (2007) · Physical Review Letters · doi:10.1103/physrevlett.99.044501 · Cited by 555
Self-citationRocchitta, G., Spanu, A., Babudieri, S., Latte, G., Madeddu, G., Galleri, G., Nuvoli, S., Bagella, P., Demartis, M., Fiore, V., et al. (2016) · Sensors · doi:10.3390/s16060780 · Cited by 555
Chen, Y., Guo, Z., Wang, X., & Qiu, C. (2008) · Journal of Chromatography A · doi:10.1016/j.chroma.2007.10.026 · Cited by 316
Electrokinetic particle translocation through a nanopore
Ai, Y., & Qian, S. (2011) · Physical Chemistry Chemical Physics · doi:10.1039/c0cp02267e · Cited by 86
Metadata
- Authors
- Wang, Y.-C., Stevens, A. L., & Han, J.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-06-10
- Volume
- 77
- Issue
- 14
- Pages
- 4293-4299
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2005644024
- Cited by
- 618
- References
- 1
- FWCI
- 25.06
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
