The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
High-Performance Mass Spectrometry: Fourier Transform Ion Cyclotron Resonance at 14.5 Tesla
Abstract
We describe the design and current performance of a 14.5 T hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometer. Ion masses are routinely determined at 4-fold better mass accuracy and 2-fold higher resolving power than similar 7 T systems at the same scan rate. The combination of high magnetic field and strict control of the number of trapped ions results in external calibration broadband mass accuracy typically less than 300 ppb rms, and a resolving power of 200,000 (m/Delta m50% at m/z 400) is achieved at greater than 1 mass spectrum per second. Novel ion storage optics and methodology increase the maximum number of ions that can be delivered to the FTICR cell, thereby improving dynamic range for tandem mass spectrometry and complex mixture applications.
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Citations
Cites
Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange
Lanman, J., Lam, T. T., Emmett, M. R., Marshall, A. G., Sakalian, M., & Prevelige, P. E. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb790 · Cited by 164
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Cited by
Zubarev, R. A., & Makarov, A. (2013) · Analytical Chemistry · doi:10.1021/ac4001223 · Cited by 658
Top Down proteomics: Facts and perspectives
Catherman, A. D., Skinner, O. S., & Kelleher, N. L. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.02.041 · Cited by 507
“5 T version of the LTQ-FT-ICR instrument has also been reported, featuring approximately 4-fold higher mass accuracy and twice the resolving power of the 7T instrument [99].”
MethodPrecision proteomics: The case for high resolution and high mass accuracy
Mann, M., & Kelleher, N. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800788105 · Cited by 450
Hendrickson, C. L., Quinn, J. P., Kaiser, N. K., Smith, D. F., Blakney, G. T., Chen, T., Marshall, A. G., Weisbrod, C. R., & Beu, S. C. (2015) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-015-1182-2 · Cited by 278
Self-citationHigh Resolution Mass Spectrometry
Xian, F., Hendrickson, C. L., & Marshall, A. G. (2012) · Analytical Chemistry · doi:10.1021/ac203191t · Cited by 281
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Metadata
- Authors
- Schaub, T. M., Hendrickson, C. L., Horning, S., Quinn, J. P., Senko, M. W., & Marshall, A. G.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-05-09
- Volume
- 80
- Issue
- 11
- Pages
- 3985-3990
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2000858971
- Cited by
- 192
- References
- 1
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- closed
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