The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Secondary Electrospray Ionization Ion Mobility Spectrometry/Mass Spectrometry of Illicit Drugs
Abstract
A secondary electrospray ionization (SESI) method was developed as a nonradioactive ionization source for ion mobility spectrometry (IMS). This SESI method relied on the gas-phase interaction between charged particles created by electrospray ionization (ESI) and neutral gaseous sample molecules. Mass spectrometry (MS) was used as the detection method after ion mobility separation for ion identification. Preliminary investigations focussed on understanding the ionization process of SESI. The performance of ESI-IMS and SESI-IMS for illicit drug detection was evaluated by determining the analytical figures of merit. In general, SESI had a higher ionization efficiency for small volatile molecules compared with the electrospray method. The potential of developing a universal interface for both GC- and LC-MS with an addition stage of mobility separation was demonstrated.
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Cites
Hill, H. H., Siems, W. F., & St. Louis, R. H. (1990) · Analytical Chemistry · doi:10.1021/ac00222a001 · Cited by 737
Self-citationIon formation from charged droplets: Roles of geometry, energy, and time
Fenn, J. B. (1993) · Journal of the American Society for Mass Spectrometry · doi:10.1016/1044-0305(93)85014-o · Cited by 518
Tang, L., & Kebarle, P. (1993) · Analytical Chemistry · doi:10.1021/ac00072a020 · Cited by 506
Naked Protein Conformations: Cytochrome c in the Gas Phase
Clemmer, D. E., Hudgins, R. R., & Jarrold, M. F. (1995) · Journal of the American Chemical Society · doi:10.1021/ja00145a037 · Cited by 491
Gas-Phase Conformation of Biological Molecules: Bradykinin
Wyttenbach, T., von Helden, G., & Bowers, M. T. (1996) · Journal of the American Chemical Society · doi:10.1021/ja9535928 · Cited by 384
von Helden, G., Wyttenbach, T., & Bowers, M. T. (1995) · Science · doi:10.1126/science.267.5203.1483 · Cited by 363
Electrospray Ionization Ion Mobility Spectrometry
Wittmer, D., Chen, Y. H., Luckenbill, B. K., & Hill, H. H. (1994) · Analytical Chemistry · doi:10.1021/ac00086a021 · Cited by 216
Self-citationOxidation of peptides during electrospray ionization
Morand, K. L., Talbo, G. H., & Mann, M. (1993) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.1290070811 · Cited by 127
Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry
Snyder, A. P. (1996) · ACS symposium series · doi:10.1021/bk-1995-0619 · Cited by 121
Plasma chromatography of heroin and cocaine with mass-identified mobility spectra
Karasek, F. W., Hill, H. H., & Kim, S. H. (1976) · Journal of Chromatography A · doi:10.1016/0021-9673(76)80009-x · Cited by 79
Self-citation
Cited by
Organic Reactions in Microdroplets: Reaction Acceleration Revealed by Mass Spectrometry
Yan, X., Bain, R. M., & Cooks, R. G. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201602270 · Cited by 583
Review on ion mobility spectrometry. Part 1: current instrumentation
Cumeras, R., Figueras, E., Davis, C. E., Baumbach, J. I., & Gràcia, I. (2015) · The Analyst · doi:10.1039/c4an01100g · Cited by 459
Metadata
- Authors
- Wu, C., Siems, W. F., & Hill, H. H.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1999-12-11
- Volume
- 72
- Issue
- 2
- Pages
- 396-403
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W1969724828
- Cited by
- 278
- References
- 11
- FWCI
- 2.13
- Type
- journal article
- Language
- en
- Open access
- closed
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