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Exploring Iron Withholding by the Innate Immune Protein Human Calprotectin
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“According to reports, calprotectin (CP) withheld iron from P. aeruginosa by using the His6 site (Zygiel and Nolan 2019).”
From Nutritional Immunity in Wound Infection: Unveiling the Role of Dietary Elements in Host–Pathogen Interaction (2025) · cites this paper as Zygiel and Nolan 2019
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Cites
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Hood, M. I., & Skaar, E. P. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2836 · Cited by 1,535
Iron in infection and immunity
Cassat, J. E., & Skaar, E. P. (2013) · Cell Host & Microbe · doi:10.1016/j.chom.2013.04.010 · Cited by 1,214
Mechanisms of mammalian iron homeostasis
Pantopoulos, K., Porwal, S. K., Tartakoff, A., & Devireddy, L. (2012) · Biochemistry · doi:10.1021/bi300752r · Cited by 598
Human calprotectin is an iron-sequestering host-defense protein
Nakashige, T. G., Zhang, B., Krebs, C., & Nolan, E. M. (2015) · Nature Chemical Biology · doi:10.1038/nchembio.1891 · Cited by 291
Self-citationPhenazine-1-carboxylic acid promotes bacterial biofilm development via ferrous iron acquisition
Wang, Y., Wilks, J. C., Danhorn, T., Ramos, I., Croal, L., & Newman, D. K. (2011) · Journal of Bacteriology · doi:10.1128/jb.00396-11 · Cited by 239
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Nickel Sequestration by the Host-Defense Protein Human Calprotectin
Nakashige, T. G., Zygiel, E. M., Drennan, C. L., & Nolan, E. M. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b01212 · Cited by 125
Self-citationZygiel, E. M., Nelson, C. E., Brewer, L. K., Oglesby-Sherrouse, A. G., & Nolan, E. M. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.006819 · Cited by 76
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Cited by
Sorted by citations
Klebba, P. E., Newton, S. M. C., Six, D. A., Kumar, A., Yang, T., Nairn, B. L., Munger, C., & Chakravorty, S. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01005 · Cited by 150
Zygiel, E. M., Obisesan, A. O., Nelson, C. E., Oglesby, A. G., & Nolan, E. M. (2021) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.015975 · Cited by 36
Self-citationChen, C., Hu, X., He, D., He, X., & Shen, L. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70854 · Cited by 6
Role of Metal Availability in Modulating Antibiotic Efficacy
Velez, A. (2025) · The University of North Carolina at Chapel Hill University Libraries · doi:10.17615/qh5n-2n35
Metadata
- Authors
- Zygiel, E. M., & Nolan, E. M.
- Affiliations
- Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
- ORCID
- Nolan, Elizabeth M.
- Venue
- Accounts of Chemical Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2019-08-05
- Volume
- 52
- Issue
- 8
- Pages
- 2301-2308
- ISSN
- 0001-4842
- 1520-4898
- PMC
- PMC6702060
- Cited by
- 34
- References
- 9
- Language
- en
- Licence
- Funders
- National Institute of General Medical Sciences (R01 GM118695, R01 GM126376)
- National Science Foundation
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- CoChat. (2026). Citation check: Exploring Iron Withholding by the Innate Immune Protein Human Calprotectin. https://app.cochat.ai/papers/10.1021/acs.accounts.9b00250
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- Zygiel, E. M., & Nolan, E. M. (2019). Exploring Iron Withholding by the Innate Immune Protein Human Calprotectin. Accounts of Chemical Research. https://doi.org/10.1021/acs.accounts.9b00250