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Aβ-mediated ROS production by Cu ions: Structural insights, mechanisms and relevance to Alzheimer's disease

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Cu(II) Affinity for the Alzheimer’s Peptide: Tyrosine Fluorescence Studies Revisited

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Deprotonation of the Asp1Ala2 Peptide Bond Induces Modification of the Dynamic Copper(II) Environment in the Amyloid‐β Peptide near Physiological pH

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Identification of key structural features of the elusive Cu–Aβ complex that generates ROS in Alzheimer’s disease

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The Catalytically Active Copper‐Amyloid‐Beta State: Coordination Site Responsible for Reactive Oxygen Species Production

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Bioinorganic Chemistry of Parkinson’s Disease: Structural Determinants for the Copper-Mediated Amyloid Formation of Alpha-Synuclein

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Electrochemical and homogeneous electron transfers to the Alzheimer amyloid-β copper complex follow a preorganization mechanism

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Amyloid β−Cu2+Complexes in both Monomeric and Fibrillar Forms Do Not Generate H2O2Catalytically but Quench Hydroxyl Radicals

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Reevaluation of Copper(I) Affinity for Amyloid‐β Peptides by Competition with Ferrozine—An Unusual Copper(I) Indicator

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Mutual interference of Cu and Zn ions in Alzheimer's disease: perspectives at the molecular level

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Reaction Rates and Mechanism of the Ascorbic Acid Oxidation by Molecular Oxygen Facilitated by Cu(II)-Containing Amyloid-β Complexes and Aggregates

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Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing

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Metal-catalyzed oxidation of Aβ and the resulting reorganization of Cu binding sites promote ROS production

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An integrated study of the affinities of the Aβ16 peptide for Cu( i ) and Cu( ii ): implications for the catalytic production of reactive oxygen species

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Zn impacts Cu coordination to amyloid-β, the Alzheimer's peptide, but not the ROS production and the associated cell toxicity

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Copper(I)-α-Synuclein Interaction: Structural Description of Two Independent and Competing Metal Binding Sites

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Copper binding and redox chemistry of the Aβ16 peptide and its variants: insights into determinants of copper-dependent reactivity

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Copper(I/II), α/β‐Synuclein and Amyloid‐β: Menage à Trois?

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Copper Coordination to Native N-Terminally Modified versus Full-Length Amyloid-β: Second-Sphere Effects Determine the Species Present at Physiological pH

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Copper( i ) targeting in the Alzheimer's disease context: a first example using the biocompatible PTA ligand

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Is ascorbate Dr Jekyll or Mr Hyde in the Cu(Aβ) mediated oxidative stress linked to Alzheimer's disease?

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Redox Cycling of Copper–Amyloid β 1–16 Peptide Complexes Is Highly Dependent on the Coordination Mode

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A new water-soluble Cu(II) chelator that retrieves Cu from Cu(amyloid-β) species, stops associated ROS production and prevents Cu(II)‐induced Aβ aggregation

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Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance

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A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation

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CuII Binding Properties of N-Truncated Aβ Peptides: In Search of Biological Function

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Binding and Reactivity of Copper to R1 and R3 Fragments of tau Protein

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Current understanding of metal-dependent amyloid-β aggregation and toxicity

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Copper and cuproptosis: new therapeutic approaches for Alzheimer’s disease

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Impact of N‐Truncated Aβ Peptides on Cu‐ and Cu(Aβ)‐Generated ROS: Cu^I Matters!

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Mechanistic approaches for chemically modifying the coordination sphere of copper–amyloid-β complexes

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Structural analysis of copper(I) interaction with amyloid β peptide

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Structural Insight into Redox Dynamics of Copper Bound N-Truncated Amyloid-β Peptides from in Situ X-ray Absorption Spectroscopy

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Both metal-chelating and free radical-scavenging synthetic pentapeptides as efficient inhibitors of reactive oxygen species generation

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A β-sheet-targeted theranostic agent for diagnosing and preventing aggregation of pathogenic peptides in Alzheimer’s disease

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The reactivity of copper complexes with neuronal peptides promoted by catecholamines and its impact on neurodegeneration

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Development of Cu( ii )-specific peptide shuttles capable of preventing Cu–amyloid beta toxicity and importing bioavailable Cu into cells

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Mechanism of oxidative stress and neurotoxicity associated with heme and copper–Aβ relevant to Alzheimer's disease

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Copper Transporters? Glutathione Reactivity of Products of Cu–Aβ Digestion by Neprilysin

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His6, His13, and His14 residues in Aβ 1–40 peptide significantly and specifically affect oligomeric equilibria

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The aroylhydrazone INHHQ prevents memory impairment induced by Alzheimer’s-linked amyloid-β oligomers in mice

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Bio-Inspired Casein-Derived Antioxidant Peptides Exhibiting a Dual Direct/Indirect Mode of Action

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Oxidative Damages on the Alzheimer’s Related-Aβ Peptide Alters Its Ability to Assemble

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A Combined NMR and UV–Vis Approach to Evaluate Radical Scavenging Activity of Rosmarinic Acid and Other Polyphenols

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A Comparative Study between Lycorine and Galantamine Abilities to Interact with AMYLOID β and Reduce In Vitro Neurotoxicity

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New mescaline-related N-acylhydrazone and its unsubstituted benzoyl derivative: Promising metallophores for copper-associated deleterious effects relief in Alzheimer's disease

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Unexpected Trends in Copper Removal from Aβ Peptide: When Less Ligand Is Better and Zn Helps

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Alzheimer’s Disease and Retinal Degeneration: A Glimpse at Essential Trace Metals in Ocular Fluids and Tissues

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Role of PTA in the prevention of Cu(amyloid-β) induced ROS formation and amyloid-β oligomerisation in the presence of Zn

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A Cu-bis(imidazole) Substrate Intermediate Is the Catalytically Competent Center for Catechol Oxidase Activity of Copper Amyloid-β

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Rationally Designed Cu(I) Ligand to Prevent CuAβ-Generated ROS Production in the Alzheimer’s Disease Context

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Combating multiple aetiologies of Alzheimer's disease to rescue behavioural deficits

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On the propagation of the OH radical produced by Cu-amyloid beta peptide model complexes. Insight from molecular modelling

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Hybrid Bis-Histidine Phenanthroline-Based Ligands to Lessen Aβ-Bound Cu ROS Production: An Illustration of Cu(I) Significance

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Molecular interactions, structural effects, and binding affinities between silver ions (Ag+) and amyloid beta (Aβ) peptides

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Mutations of Histidine 13 to Arginine and Arginine 5 to Glycine Are Responsible for Different Coordination Sites of Zinc(II) to Human and Murine Peptides

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Dual mode of voltammetric studies on Cu( ii ) complexes of His2 peptides: phosphate and peptide sequence recognition

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Ability of Azathiacyclen Ligands To Stop Cu(Aβ)‐Induced Production of Reactive Oxygen Species: [3N1S] Is the Right Donor Set

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New BDNF and NT-3 Cyclic Mimetics Concur with Copper to Activate Trophic Signaling Pathways as Potential Molecular Entities to Protect Old Brains from Neurodegeneration

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Cu(II) Binding to the N-Terminal Model Peptide of the Human Ctr2 Transporter at Lysosomal and Extracellular pH

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The Palladium(II) Complex of Aβ4−16 as Suitable Model for Structural Studies of Biorelevant Copper(II) Complexes of N-Truncated Beta-Amyloids

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Oxidative Activity of Copper Ions in Ternary Systems With N‐Truncated Amyloid Beta Peptides and Low Molecular Weight Substances

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Solid-state and solution characterizations of [(TMPA)Cu(II)(SO3)] and [(TMPA)Cu(II)(S2O3)] complexes: Application to sulfite and thiosulfate fast detection

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Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of Aβ by Metal Ion Stripping and Redox Silencing

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Molecular dynamics simulations of copper binding to N-terminus mutants of amyloid-β

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Investigating Cu(I) binding to model peptides of N-terminal Aβ isoforms

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The Angiotensin Metabolite His-Leu Is a Strong Copper Chelator Forming Highly Redox Active Species

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Accelerated Molecular Dynamics to Explore the Binding of Transition Metals to Amyloid-β

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Fusobacterium nucleatum’s Copper-FomA Proteins: Driving Cancer Forward

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The redox-active Cu-FomA complex: the mode that provides coordination of Cu II /Cu I ions during the reduction/oxidation cycle

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Exploration of Lycorine and Copper(II)’s Association with the N-Terminal Domain of Amyloid β

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4‐Dimethylamino‐1,8‐Naphthalimide as a Fluorescence Signal Amplification for Site Selective and in Situ Probing of the Hydroxyl Radical

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FURTHER DEVELOPMENT OF THE NEW GENERATION OF NACYLHYDRAZONES CONTAINING THE 1-METHYLIMIDAZOLE GROUP AND THEIR EVALUATION AGAINST MODELS OF ENDOCRINE AND NEUROENDOCRINE AGGREGOPATHIES

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Cu(I) Is a Game Changer in the Arrest of Cu(Aβ)‐Induced ROS Production in the Presence of Competing Zn(II) Ions

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Synthesis and characterization of copper-peptide systems for oxidation catalysis

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Cu(I/II) complexes as models of the copper-(amyloid-beta) in-between state responsible for oxidative stress in Alzheimer's disease

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Etudes spectroscopiques d'une protéine périplasmique impliquée dans un nouveau mécanisme de résistance bactérienne au cuivre

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Peptides as unique tools to modulate redox levels: towards applications in living cells and in vivo

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Phospholipids and amyloid-β compete for copper-induced reactive oxygen species production in the context of Alzheimer's disease

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Targeting Cu2+ mediated Aβ aggregation and ROS generation using 2-(4-aminophenyl)benzothiazole–based chelators

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Reaction Rates and Mechanism of the Ascorbic Acid Oxidation by Molecular Oxygen Facilitated by Cu(II)-Containing Amyloid-β Complexes and Aggregates

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Oxidative Activity of Copper Ions in Ternary Systems With N‐Truncated Amyloid Beta Peptides and Low Molecular Weight Substances

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