Biological metals and metal-targeting compounds in major neurodegenerative diseases

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Neurodegenerative diseases and oxidative stress

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TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

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The neurobiology of zinc in health and disease

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The metallobiology of Alzheimer's disease

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Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

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The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction

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Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

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Dramatic Aggregation of Alzheimer Aβ by Cu(II) Is Induced by Conditions Representing Physiological Acidosis

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Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial

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The changing scene of amyotrophic lateral sclerosis

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Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity

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Zinc in the physiology and pathology of the CNS

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Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus

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ZnT-3, a putative transporter of zinc into synaptic vesicles

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The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein

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Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

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Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

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The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I)

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Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

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High-Affinity Zinc Inhibition of NMDA NR1–NR2A Receptors

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Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

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Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo

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Copper is required for oncogenic BRAF signalling and tumorigenesis

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The redox chemistry of the Alzheimer's disease amyloid β peptide

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Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

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Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with β-amyloid deposits in Alzheimer’s disease

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Metalloenzyme-like Activity of Alzheimer's Disease β-Amyloid

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Metal Binding and Oxidation of Amyloid-β within Isolated Senile Plaque Cores: Raman Microscopic Evidence

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An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

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The A53T α-Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity

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Loss of iron triggers PINK1/Parkin‐independent mitophagy

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In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

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Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses

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Copper in the brain and Alzheimer’s disease

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Affinity gradients drive copper to cellular destinations

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Aqueous Dissolution of Alzheimer's Disease Aβ Amyloid Deposits by Biometal Depletion

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A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients

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Measurement of Intracellular Free Zinc in Living Cortical Neurons: Routes of Entry

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Anti-inflammatory drugs and Alzheimer disease

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Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

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PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses

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Iron, Neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes

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Evidence that the β-Amyloid Plaques of Alzheimer's Disease Represent the Redox-silencing and Entombment of Aβ by Zinc

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Cognitive Loss in Zinc Transporter-3 Knock-Out Mice: A Phenocopy for the Synaptic and Memory Deficits of Alzheimer's Disease?

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Induction of Neuronal Apoptosis by Thiol Oxidation

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Copper Mediates Dityrosine Cross-Linking of Alzheimer's Amyloid-β

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Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide

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Metals and amyloid‐β in Alzheimer's disease

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Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains

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Overexpression of Alzheimer's Disease Amyloid-β Opposes the Age-dependent Elevations of Brain Copper and Iron

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Brain ferritin iron may influence age- and gender-related risks of neurodegeneration

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The Neurophysiology and Pathology of Brain Zinc

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Modulation of A beta adhesiveness and secretase site cleavage by zinc.

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Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice

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Endogenous amyloid‐β is necessary for hippocampal synaptic plasticity and memory

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Zinc-induced Alzheimer's Aβ1–40 Aggregation Is Mediated by Conformational Factors

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Iron (III) induces aggregation of hyperphosphorylated τ and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease

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Zinc ions promote Alzheimer Aβ aggregation via population shift of polymorphic states

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Nerve endings from rat brain tissue release copper upon depolarization. A possible role in regulating neuronal excitability.

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