Matrix Mediated Viral Gene Delivery: A Review
Abstract
Polymeric matrices inherently protect viral vectors from pre-existing immune conditions, limit dissemination to off-target sites, and can sustain vector release. Advancing methodologies in development of particulate based vehicles have led to improved encapsulation of viral vectors. Polymeric delivery systems have contributed to increasing cellular transduction, responsive release mechanisms, cellular infiltration, and cellular signaling. Synthetic polymers are easily customizable, and are capable of balancing matrix retention with cellular infiltration. Natural polymers contain inherent biorecognizable motifs adding therapeutic efficacy to the incorporated viral vector. Recombinant polymers use highly conserved motifs to carefully engineer matrices, allowing for precise design including elements of vector retention and responsive release mechanisms. Composite polymer systems provide opportunities to create matrices with unique properties. Carefully designed matrices can control spatiotemporal release patterns that synergize with approaches in regenerative medicine and antitumor therapies.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
bioPROTACs would most likely be delivered as mRNA or DNA constructs via a viral vector gene delivery system or in a nanoparticle.
“Indeed, bioPROTACs would most likely be delivered as mRNA or DNA constructs via a viral vector gene delivery system204–206 or in a nanoparticle207–209.”
From PROTAC targeted protein degraders: the past is prologue (2022) · cites this paper as [208]
Cites
Alginate: Properties and biomedical applications
Lee, K. Y., & Mooney, D. J. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.06.003 · Cited by 8,218 · see citing works
Designing hydrogels for controlled drug delivery
Li, J., & Mooney, D. J. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2016.71 · Cited by 4,891 · see citing works
Porous scaffold design for tissue engineering
Hollister, S. J. (2005) · Nature Materials · doi:10.1038/nmat1421 · Cited by 3,979 · see citing works
Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan—a review
George, M., & Abraham, T. E. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.04.017 · Cited by 2,012 · see citing works
Biomedical applications of collagen
Lee, C. H., Singla, A., & Lee, Y. (2001) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(01)00691-3 · Cited by 1,948 · see citing works
Polymers for Drug Delivery Systems
Liechty, W. B., Kryscio, D. R., Slaughter, B. V., & Peppas, N. A. (2010) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-073009-100847 · Cited by 1,608 · see citing works
Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery
Kabanov, A. V., Batrakova, E. V., & Alakhov, V. Y. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00009-3 · Cited by 1,474 · see citing works
Dunbar, C. E., High, K. A., Joung, J. K., Kohn, D. B., Ozawa, K., & Sadelain, M. (2018) · Science · doi:10.1126/science.aan4672 · Cited by 1,410 · see citing works
Malafaya, P. B., Silva, G. A., & Reis, R. L. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.03.012 · Cited by 1,400 · see citing works
Gene Editing of <i>CCR5</i> in Autologous CD4 T Cells of Persons Infected with HIV
Tebas, P., Stein, D., Tang, W. W., Frank, I., Wang, S. Q., Lee, G., Spratt, S. K., Surosky, R. T., Giedlin, M. A., Nichol, G., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1300662 · Cited by 1,357 · see citing works
A Review of Poloxamer 407 Pharmaceutical and Pharmacological Characteristics
Dumortier, G., Grossiord, J., Agnely, F., & Chaumeil, J. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9104-4 · Cited by 1,273 · see citing works
Cyclodextrin Rotaxanes and Polyrotaxanes
Wenz, G., Han, B., & Müller, A. H. E. (2006) · Chemical Reviews · doi:10.1021/cr970027+ · Cited by 1,245 · see citing works
Effect of genome size on AAV vector packaging
Wu, Z., Yang, H., & Colosi, P. (2010) · Molecular Therapy · doi:10.1038/mt.2009.255 · Cited by 1,025 · see citing works
Development of biocompatible synthetic extracellular matrices for tissue engineering
Kim, B., & Mooney, D. J. (1998) · Trends in biotechnology · doi:10.1016/s0167-7799(98)01191-3 · Cited by 934 · see citing works
Gene therapy clinical trials worldwide to 2017: An update
Ginn, S. L., Amaya, A. K., Alexander, I. E., Edelstein, M., & Abedi, M. R. (2018) · The Journal of Gene Medicine · doi:10.1002/jgm.3015 · Cited by 903 · see citing works
Rho, K. S., Jeong, L., Lee, G., Seo, B., Park, Y. J., Hong, S., Roh, S., Cho, J. J., Park, W. H., & Min, B. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.08.004 · Cited by 874 · see citing works
LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex
Mi, S., Lee, X., Shao, Z., Thill, G., Ji, B., Relton, J. K., Levesque, M., Allaire, N., Perrin, S., Sands, B., et al. (2004) · Nature Neuroscience · doi:10.1038/nn1188 · Cited by 827 · see citing works
Gene therapy clinical trials worldwide to 2012 – an update
Ginn, S., Alexander, I. E., Edelstein, M. L., Abedi, M. R., & Wixon, J. (2013) · Journal of Gene Medicine · doi:10.1002/jgm.2698 · Cited by 807 · see citing works
The origins and evolution of “controlled” drug delivery systems
Hoffman, A. S. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.08.012 · Cited by 740 · see citing works
Fibrin gels and their clinical and bioengineering applications
Janmey, P. A., Winer-Jones, J. P., & Weisel, J. W. (2008) · Journal of The Royal Society Interface · doi:10.1098/rsif.2008.0327 · Cited by 683 · see citing works
Degradation of Partially Oxidized Alginate and Its Potential Application for Tissue Engineering
Bouhadir, K. H., Lee, K. Y., Alsberg, E., Damm‐Ganamet, K. L., Anderson, K. W., & Mooney, D. J. (2001) · Biotechnology Progress · doi:10.1021/bp010070p · Cited by 672 · see citing works
Boontheekul, T., Kong, H., & Mooney, D. J. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.044 · Cited by 659 · see citing works
Lee, C. H., Shin, H. J., Cho, I. H., Kang, Y.-M., Kim, I. A., Park, K., & Shin, J. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.04.037 · Cited by 633 · see citing works
Human bone marrow stromal cell responses on electrospun silk fibroin mats
Jin, H., Chen, J., Karageorgiou, V., Altman, G. H., & Kaplan, D. L. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00609-4 · Cited by 631 · see citing works
LINGO-1 negatively regulates myelination by oligodendrocytes
Mi, S., Miller, R. H., Lee, X., Scott, M. L., Shulag-Morskaya, S., Shao, Z., Chang, J., Thill, G., Levesque, M., Zhang, M., et al. (2005) · Nature Neuroscience · doi:10.1038/nn1460 · Cited by 628 · see citing works
Meinel, L., Karageorgiou, V., Fajardo, R., Snyder, B. D., Patil, V. R. S., Zichner, L., Kaplan, D. L., Langer, R., & Vunjak‐Novakovic, G. (2003) · Annals of Biomedical Engineering · doi:10.1023/b:abme.0000007796.48329.b4 · Cited by 561 · see citing works
Kaufman, H. L., Kim, D. W., DeRaffele, G., Mitcham, J., Coffin, R., & Kim‐Schulze, S. (2009) · Annals of Surgical Oncology · doi:10.1245/s10434-009-0809-6 · Cited by 519 · see citing works
Form, function, and use of retroviral Gag proteins
Wills, J. W., & Craven, R. C. (1991) · AIDS · doi:10.1097/00002030-199106000-00002 · Cited by 515 · see citing works
Chung, C., & Burdick, J. A. (2008) · Tissue Engineering Part A · doi:10.1089/ten.tea.2008.0067 · Cited by 465 · see citing works
Silk implants for the healing of critical size bone defects
Meinel, L., Fajardo, R., Hofmann, S., Langer, R., Chen, J., Snyder, B. D., Vunjak‐Novakovic, G., & Kaplan, D. L. (2005) · Bone · doi:10.1016/j.bone.2005.06.010 · Cited by 460 · see citing works
Collagen: Molecular Diversity in the Body's Protein Scaffold
Eyre, D. R. (1980) · Science · doi:10.1126/science.7355290 · Cited by 455 · see citing works
Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA+ Metastatic Colorectal Cancers
Zhang, C., Wang, Z., Yang, Z., Wang, M., Li, S., Li, Y., Zhang, R., Xiong, Z., Wei, Z., Shen, J., et al. (2017) · Molecular Therapy · doi:10.1016/j.ymthe.2017.03.010 · Cited by 454 · see citing works
Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering
Chung, B. G., Lee, K. H., Khademhosseini, A., & Lee, S. (2011) · Lab on a Chip · doi:10.1039/c1lc20859d · Cited by 437 · see citing works
Protein-based materials, toward a new level of structural control
van Hest, J. C. M., & Tirrell, D. A. (2001) · Chemical Communications · doi:10.1039/b105185g · Cited by 416 · see citing works
The application of recombinant human collagen in tissue engineering
Yang, C., Hillas, P. J., B??ez, J. A., Nokelainen, M., Balan, J., Tang, J., Spiro, R., & Polarek, J. W. (2004) · BioDrugs · doi:10.2165/00063030-200418020-00004 · Cited by 385 · see citing works
Shao, Z., Browning, J. L., Lee, X., Scott, M. L., Shulga-Morskaya, S., Allaire, N., Thill, G., Levesque, M., Sah, D. W. Y., McCoy, J. M., et al. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.050 · Cited by 383 · see citing works
Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells
Varghese, S., Hwang, N. S.-Y., Canver, A. C., Theprungsirikul, P., Lin, D. W., & Elisseeff, J. H. (2007) · Matrix Biology · doi:10.1016/j.matbio.2007.07.002 · Cited by 380 · see citing works
Outcomes Following Gene Therapy in Patients With Severe Wiskott-Aldrich Syndrome
Hacein‐Bey‐Abina, S., Gaspar, H. B., Blondeau, J., Caccavelli, L., Charrier, S., Buckland, K. F., Pïcard, C., Six, E. M., Himoudi, N., Gilmour, K. C., et al. (2015) · JAMA · doi:10.1001/jama.2015.3253 · Cited by 378 · see citing works
Structure of the Prefusion Form of the Vesicular Stomatitis Virus Glycoprotein G
Roche, S., Rey, F. A., Gaudin, Y., & Bressanelli, S. (2007) · Science · doi:10.1126/science.1135710 · Cited by 364 · see citing works
Controlling Rigidity and Degradation of Alginate Hydrogels via Molecular Weight Distribution
Kong, H. J., Kaigler, D., Kim, K., & Mooney, D. J. (2004) · Biomacromolecules · doi:10.1021/bm049879r · Cited by 351 · see citing works
Stenzel, K. H., Miyata, T., & Rubin, A. L. (1974) · Annual Review of Biophysics and Bioengineering · doi:10.1146/annurev.bb.03.060174.001311 · Cited by 337 · see citing works
The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes
Gao, Y., Liu, S., Huang, J., Guo, W., Chen, J., Zhang, L., Zhao, B., Peng, J. C., Wang, Y., Wang, Y., et al. (2014) · BioMed Research International · doi:10.1155/2014/648459 · Cited by 329 · see citing works
Genetic Engineering of Structural Protein Polymers
Cappello, J., Crissman, J. W., Dorman, M., Mikolajczak, M., Textor, G., Marquet, M., & Ferrari, F. (1990) · Biotechnology Progress · doi:10.1021/bp00003a006 · Cited by 323 · see citing works
Mechanical and thermal properties of dragline silk from the spider Nephila clavipes
Cunniff, P. M., Fossey, S. A., Auerbach, M. A., Song, J. W., Kaplan, D. L., Adams, W. W., Eby, R. K., Mahoney, D. V., & Vezie, D. L. (1994) · Polymers for Advanced Technologies · doi:10.1002/pat.1994.220050801 · Cited by 297 · see citing works
Coaxial electrospun fibers: applications in drug delivery and tissue engineering
Lu, Y., Huang, J., Yu, G., Cardenas, R., Wei, S., Wujcik, E. K., & Guo, Z. (2016) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1391 · Cited by 285 · see citing works
Oncolytic Viral Therapy and the Immune System: A Double-Edged Sword Against Cancer
Marelli, G., Howells, A., Lemoine, N. R., & Wang, Y. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00866 · Cited by 284 · see citing works
Biomaterials Applications for Nanomedicine
Pignatello, R. (2011) · InTech eBooks · doi:10.5772/1957 · Cited by 274 · see citing works
Unraveling the complex story of immune responses to AAV vectors trial after trial.
Vandamme, C., Adjali, O., & Mingozzi, F. (2017) · Human Gene Therapy · doi:10.1089/hum.2017.150 · Cited by 234 · see citing works
Aligned Core–Shell Nanofibers Delivering Bioactive Proteins
Liao, I., Chew, S. Y., & Leong, K. W. (2006) · Nanomedicine · doi:10.2217/17435889.1.4.465 · Cited by 224 · see citing works
The Acidic Microclimate in Poly(lactide-co-glycolide) Microspheres Stabilizes Camptothecins
Shenderova, A., Burke, T. G., & Schwendeman, S. P. (1999) · Pharmaceutical Research · doi:10.1023/a:1018876308346 · Cited by 222 · see citing works
Cryo-electron tomography of vaccinia virus
Cyrklaff, M., Risco, C., Fernández, J., Jiménez, M. V., Estéban, M., Baumeister, W. P., & Carrascosa, J. L. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409825102 · Cited by 215 · see citing works
Degradation Behavior of Covalently Cross-Linked Poly(aldehyde guluronate) Hydrogels
Lee, K. Y., Bouhadir, K. H., & Mooney, D. J. (1999) · Macromolecules · doi:10.1021/ma991286z · Cited by 211 · see citing works
In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy
Megeed, Z., Haider, M. A., Li, D., O'Malley, B. W., Cappello, J., & Ghandehari, H. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.10.027 · Cited by 202 · see citing works
Self-citationSelf-assembly and optically triggered disassembly of hierarchical dendron–virus complexes
Kostiainen, M. A., Kasyutich, O. I., Cornelissen, J. J. L. M., & Nolte, R. J. M. (2010) · Nature Chemistry · doi:10.1038/nchem.592 · Cited by 190 · see citing works
The significance of angiogenesis in guided bone regeneration. A case report of a rabbit experiment.
Schmid, J., Wallkamm, B., Hämmerle, C. H. F., Gogolewski, S., & Lang, N. P. (1997) · Clinical Oral Implants Research · doi:10.1034/j.1600-0501.1997.080311.x · Cited by 190 · see citing works
van Loo, N.-D., Fortunati, E., Ehlert, E., Rabelink, M. J. W. E., Grosveld, F. G., & Scholte, B. J. (2001) · Journal of Virology · doi:10.1128/jvi.75.2.961-970.2001 · Cited by 188 · see citing works
Paul, A., Manoharan, V., Krafft, D., Assmann, A., Uquillas, J. A., Shin, S. R., Hasan, A., Hussain, M. A., Memić, A., Gaharwar, A. K., et al. (2016) · Journal of Materials Chemistry B · doi:10.1039/c5tb02745d · Cited by 178 · see citing works
In Situ Gelling of Alginate/Pluronic Solutions for Ophthalmic Delivery of Pilocarpine
Lin, H., Sung, K. C., & Vong, W.-J. (2004) · Biomacromolecules · doi:10.1021/bm0496965 · Cited by 177 · see citing works
Chen, J., Huang, X., Wang, Q., Huang, J., Zhang, L., Chen, X., Lei, J., & Cheng, Z. (2012) · Carcinogenesis · doi:10.1093/carcin/bgs274 · Cited by 172 · see citing works
Supramolecular cyclodextrin-based drug nanocarriers
Simões, S. M. N., Rey‐Rico, A., Concheiro, Á., & Alvarez‐Lorenzo, C. (2015) · Chemical Communications · doi:10.1039/c4cc10388b · Cited by 164 · see citing works
Gene therapy progress and prospects cancer: oncolytic viruses
Liu, T.-C., & Kirn, D. H. (2008) · Gene Therapy · doi:10.1038/gt.2008.72 · Cited by 158 · see citing works
Collagen and its interactions with chitosan III. Some biological and mechanical properties
Taravel, M. N. (1996) · Biomaterials · doi:10.1016/0142-9612(96)89663-3 · Cited by 158 · see citing works
A review of hydrogel use in fracture healing and bone regeneration
Gibbs, D., Black, C. R. M., Dawson, J. I., & Oreffo, R. O. C. (2014) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1968 · Cited by 156 · see citing works
Zhang, Y., Cheng, X., Wang, J., Wang, Y., Shi, B., Huang, C., Yang, X., & Liu, T. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.03.106 · Cited by 155 · see citing works
Sustained viral gene delivery through core-shell fibers
Liao, I., Chen, S., Liu, J. B., & Leong, K. W. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.06.007 · Cited by 151 · see citing works
Lin, H., Cheng, A. W. M., Alexander, P. G., Beck, A. M., & Tuan, R. S. (2014) · Tissue Engineering Part A · doi:10.1089/ten.tea.2013.0642 · Cited by 149 · see citing works
Isaacson, K. J., Jensen, M. M., Subrahmanyam, N. B., & Ghandehari, H. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.01.034 · Cited by 149 · see citing works
Self-citationCroyle, M. A., Callahan, S. M., Auricchio, A., Schumer, G., Linse, K. D., Wilson, J. M., Brunner, L. J., & Kobinger, G. P. (2003) · Journal of Virology · doi:10.1128/jvi.78.2.912-921.2004 · Cited by 148 · see citing works
Non-affine deformations in polymer hydrogels
Wen, Q., Basu, A., Janmey, P. A., & Yodh, A. G. (2012) · Soft Matter · doi:10.1039/c2sm25364j · Cited by 148 · see citing works
Fibrin-based delivery strategies for acute and chronic wound healing
Heher, P., Mühleder, S., Mittermayr, R., Redl, H. R., & Slezak, P. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.12.007 · Cited by 148 · see citing works
In Vivo Endochondral Bone Formation Using a Bone Morphogenetic Protein 2 Adenoviral Vector
Alden, T. D., Pittman, D. D., Hankins, G. R., Beres, E. J., Engh, J. A., Das, S., Hudson, S. B., Kerns, K. M., Kallmes, D. F., & Helm, G. A. (1999) · Human Gene Therapy · doi:10.1089/10430349950017220 · Cited by 145 · see citing works
Liljeström, V., Mikkilä, J., & Kostiainen, M. A. (2014) · Nature Communications · doi:10.1038/ncomms5445 · Cited by 143 · see citing works
The adenovirus capsid: major progress in minor proteins
Vellinga, J., van der Heijdt, S., & Hoeben, R. C. (2005) · Journal of General Virology · doi:10.1099/vir.0.80877-0 · Cited by 140 · see citing works
Controlling Degradation of Hydrogels via the Size of Crosslinked Junctions
Kong, H. J., Alsberg, E., Kaigler, D., Lee, K. Y., & Mooney, D. J. (2004) · Advanced Materials · doi:10.1002/adma.200400014 · Cited by 131 · see citing works
Mass Determination of Rous Sarcoma Virus Virions by Scanning Transmission Electron Microscopy
Vogt, V. M., & Simon, M. N. (1999) · Journal of Virology · doi:10.1128/jvi.73.8.7050-7055.1999 · Cited by 130 · see citing works
Alipogene Tiparvovec: A Review of Its Use in Adults with Familial Lipoprotein Lipase Deficiency
Scott, L. J. (2015) · Drugs · doi:10.1007/s40265-014-0339-9 · Cited by 130 · see citing works
Lim, J. Y., Hansen, J. C., Siedlecki, C. A., Hengstebeck, R. W., Cheng, J., Winograd, N., & Donahue, H. J. (2005) · Biomacromolecules · doi:10.1021/bm0503423 · Cited by 129 · see citing works
Assembly of vaccinia virus revisited: de novo membrane synthesis or acquisition from the host?
Sodeik, B., & Krijnse‐Locker, J. (2002) · Trends in Microbiology · doi:10.1016/s0966-842x(01)02256-9 · Cited by 123 · see citing works
Controlled Release of Plasmid DNA from a Genetically Engineered Silk-Elastinlike Hydrogel
Megeed, Z., Cappello, J., & Ghandehari, H. (2002) · Pharmaceutical Research · doi:10.1023/a:1016406120288 · Cited by 118 · see citing works
Self-citationAmann, E., Wolff, P., Breel, E. J., van Griensven, M., & Balmayor, E. R. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.01.064 · Cited by 117 · see citing works
Nanostructure of the Fibrin Clot
Yeromonahos, C., Polack, B., & Caton, F. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2010.04.059 · Cited by 115 · see citing works
Cytological Changes and Viral Morphogenesis during Baculovirus Infection
Williams, G. V., & Faulkner, P. (1997) · Springer eBooks · doi:10.1007/978-1-4899-1834-5_4 · Cited by 112 · see citing works
Sailaja, G. S., HogenEsch, H., North, A., Hays, J., & Mittal, S. K. (2002) · Gene Therapy · doi:10.1038/sj.gt.3301858 · Cited by 111 · see citing works
Beer, S., Matthews, C. B., Stein, C., Bd, R., Hilfinger, J. M., & Davidson, B. L. (1998) · Gene Therapy · doi:10.1038/sj.gt.3300647 · Cited by 106 · see citing works
Haider, M. A., Leung, V., Ferrari, F., Crissman, J. W., Powell, J., Cappello, J., & Ghandehari, H. (2005) · Molecular Pharmaceutics · doi:10.1021/mp049906s · Cited by 104 · see citing works
Self-citationWinet, H. (1996) · Bone · doi:10.1016/s8756-3282(96)00133-0 · Cited by 101 · see citing works
Interaction of tumor and normal blood cells with ethylene oxide and propylene oxide block copolymers
Melik‐Nubarov, N. S., Pomaz, O. O., Dorodnych, T. Y., Badun, G. A., Ksenofontov, A. L., Шемчукова, О. Б., & Arzhakov, S. A. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00208-2 · Cited by 100 · see citing works
Gene Therapy: The First Approved Gene-Based Medicines, Molecular Mechanisms and Clinical Indications
Räty, J. K., Pikkarainen, J. T., Wirth, T. C., & Ylä‐Herttuala, S. (2008) · Current Molecular Pharmacology · doi:10.2174/1874467210801010013 · Cited by 98 · see citing works
Delivery and Protection of Adenoviruses Using Biocompatible Hydrogels for Localized Gene Therapy
Schek, R. M., Hollister, S. J., & Krebsbach, P. H. (2003) · Molecular Therapy · doi:10.1016/j.ymthe.2003.10.002 · Cited by 96 · see citing works
Roos, N., Cyrklaff, M., Cudmore, S., Blasco, R., Locker, J. K., & Griffiths, G. W. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00590.x · Cited by 91 · see citing works
Mulder, G., Tallis, A. J., Marshall, V. T., Mozingo, D. W., Phillips, L., Pierce, G. F., Chandler, L. A., & Sosnowski, B. K. (2009) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2009.00541.x · Cited by 91 · see citing works
Structure of Intracellular Mature Vaccinia Virus Visualized by In Situ Atomic Force Microscopy
Malkin, A. J., McPherson, A., & Gershon, P. D. (2003) · Journal of Virology · doi:10.1128/jvi.77.11.6332-6340.2003 · Cited by 91 · see citing works
Zhang, Y., Song, J., Shi, B., Wang, Y., Chen, X., Huang, C., Yang, X., Xu, D., Cheng, X., & Chen, X. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.009 · Cited by 90 · see citing works
The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses
Thaçi, B., Ulasov, I. V., Wainwright, D. A., & Lesniak, M. S. (2011) · Oncotarget · doi:10.18632/oncotarget.231 · Cited by 89 · see citing works
In Vitro Chondrogenesis of Mesenchymal Stem Cells in Recombinant Silk-elastinlike Hydrogels
Haider, M. A., Cappello, J., Ghandehari, H., & Leong, K. W. (2007) · Pharmaceutical Research · doi:10.1007/s11095-007-9282-8 · Cited by 89 · see citing works
Self-citationLubaroff, D. M., Konety, B. R., Link, B. K., Gerstbrein, J., Madsen, T., Shannon, M., Howard, J., Paisley, J., Boeglin, D., Ratliff, T. L., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-1910 · Cited by 88 · see citing works
Cooperative colloidal self-assembly of metal-protein superlattice wires
Liljeström, V., Ora, A., Hassinen, J., Rekola, H. T., Nonappa, N., Heilala, M., Hynninen, V., Joensuu, J. J., Ras, R. H. A., Törmä, P., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-00697-z · Cited by 88 · see citing works
March, K. L., Madison, J. E., & Trapnell, B. C. (1995) · Human Gene Therapy · doi:10.1089/hum.1995.6.1-41 · Cited by 87 · see citing works
Gu, D., Nguyen, T., Gonzalez, A. M., Printz, M. A., Pierce, G. F., Sosnowski, B. A., Phillips, M. L., & Chandler, L. A. (2004) · Molecular Therapy · doi:10.1016/j.ymthe.2004.02.018 · Cited by 87 · see citing works
Luo, T., Zhang, W., Shi, B., Cheng, X., & Zhang, Y. (2011) · Clinical Oral Implants Research · doi:10.1111/j.1600-0501.2011.02164.x · Cited by 79 · see citing works
Energetics of Ca2+–EDTA interactions: calorimetric study
Griko, Y. V. (1999) · Biophysical Chemistry · doi:10.1016/s0301-4622(99)00047-2 · Cited by 79 · see citing works
Sojo, K., SAWAKI, Y., Hattori, H., Mizutani, H., & Ueda, M. (2005) · Journal of Cranio-Maxillofacial Surgery · doi:10.1016/j.jcms.2005.02.004 · Cited by 79 · see citing works
Fibrin hydrogels for lentiviral gene delivery in vitro and in vivo
Kidd, M. E., Shin, S., & Shea, L. D. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.08.036 · Cited by 78 · see citing works
Silk-elastinlike protein polymers for matrix-mediated cancer gene therapy
Gustafson, J. A., & Ghandehari, H. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.04.006 · Cited by 78 · see citing works
Self-citationSystemic dissemination of viral vectors during intratumoral injection.
Wang, Y., Hu, J., Krol, A., Li, Y.-P., Li, C., & Yuan, F. (2003) · PubMed · Cited by 77 · see citing works
Chemical and Biosynthetic Approaches to the Production of Novel Polypeptide Materials
McGrath, K. P., Tirrell, D. A., Kawai, M., Mason, T. L., & Fournier, M. J. (1990) · Biotechnology Progress · doi:10.1021/bp00003a004 · Cited by 77 · see citing works
Adenovirus Virion Stability and the Viral Genome: Size Matters
Kennedy, M. A., & Parks, R. J. (2009) · Molecular Therapy · doi:10.1038/mt.2009.202 · Cited by 71 · see citing works
Wu, H., Cen, J.-S., Zhong, Q., Chen, L., Wang, J., Deng, D. Y. B., & Wan, Y. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.11.013 · Cited by 71 · see citing works
Gustafson, J. A., Greish, K. F., Frandsen, J. L., Cappello, J., & Ghandehari, H. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.05.022 · Cited by 71 · see citing works
Self-citationPoloxamer synperonic F108 improves cellular transduction with lentiviral vectors
Höfig, I., Atkinson, M. J., Mall, S., Krackhardt, A. M., Thirion, C., & Anastasov, N. (2012) · The Journal of Gene Medicine · doi:10.1002/jgm.2653 · Cited by 69 · see citing works
Zhang, Y., Shi, B., Li, C., Wang, Y., Chen, Y., Zhang, W., Luo, T., & Cheng, X. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.02.016 · Cited by 69 · see citing works
Blume, P. A., Driver, V. R., Tallis, A. J., Kirsner, R. S., Kroeker, R., Payne, W. G., Wali, S., Marston, W. A., Dove, C., Engler, R. L., et al. (2011) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2011.00669.x · Cited by 68 · see citing works
Adenoviral Gene Delivery to Solid Tumors by Recombinant Silk–Elastinlike Protein Polymers
Hatefi, A., Cappello, J., & Ghandehari, H. (2007) · Pharmaceutical Research · doi:10.1007/s11095-006-9200-5 · Cited by 67 · see citing works
Self-citationBreen, A., Dockery, P., O’Brien, T., & Pandit, A. S. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.020 · Cited by 67 · see citing works
Menendez, M. I., Clark, D. J., Carlton, M. M., Flanigan, D. C., Jia, G., Sammet, S., Weisbrode, S. E., Knopp, M. V., & Bertone, A. L. (2011) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2011.05.007 · Cited by 67 · see citing works
Structure of high density fibrin networks probed with neutron scattering and rheology
Weigandt, K. M., Pozzo, D. C., & Porcar, L. (2009) · Soft Matter · doi:10.1039/b906256d · Cited by 65 · see citing works
Gu, X., Matsumura, Y., Tang, Y. M., Roy, S., Hoff, R., Wang, B., & Wagner, W. R. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.04.015 · Cited by 65 · see citing works
The structure of nuclear polyhedrosis viruses
Harrap, K. A. (1972) · Virology · doi:10.1016/0042-6822(72)90352-2 · Cited by 62 · see citing works
Kim, C. S., Yang, Y. J., Bahn, S. Y., & Chi, H. J. (2017) · NPG Asia Materials · doi:10.1038/am.2017.71 · Cited by 62 · see citing works
Feldman, L. J., Pastore, C., Aubailly, N., Kearney, M., Chen, D., Perricaudet, M., Steg, P. G., & Isner, J. M. (1997) · Gene Therapy · doi:10.1038/sj.gt.3300382 · Cited by 61 · see citing works
Zhang, Y., Wu, C., Luo, T., Li, S., Cheng, X., & Miron, R. J. (2012) · Bone · doi:10.1016/j.bone.2012.06.029 · Cited by 61 · see citing works
Lee, H. H., Haleem, A. M., Yao, V., Li, J., Xiao, X., & Chu, C. R. (2011) · Tissue Engineering Part A · doi:10.1089/ten.tea.2010.0586 · Cited by 61 · see citing works
Jung, B., Oh, E., Hong, J., Lee, Y., Park, K. D., & Yun, C. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.09.009 · Cited by 61 · see citing works
Structure and Assembly of Intracellular Mature Vaccinia Virus: Isolated-Particle Analysis
Griffiths, G. W., Wepf, R. A., Wendt, T. G., Locker, J. K., Cyrklaff, M., & Roos, N. (2001) · Journal of Virology · doi:10.1128/jvi.75.22.11034-11055.2001 · Cited by 60 · see citing works
Electrospun nanofibrous scaffolds for controlled release of adeno-associated viral vectors
Lee, S., Kim, J., Chu, H. S., Kim, G.-W., Won, J., & Jang, J. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.06.035 · Cited by 59 · see citing works
Siemens, D. R., Elzey, B. D., Lubaroff, D. M., Bohlken, C., Jensen, R. J., Swanson, A. K., & Ratliff, T. L. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.2.731 · Cited by 58 · see citing works
Stilhano, R. S., Madrigal, J. L., Wong, K. B., Williams, P. A., Martin, P. K. M., Yamaguchi, F. S. M., Samoto, V. Y., Han, S. W., & Silva, E. A. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.06.047 · Cited by 58 · see citing works
Controlled release from recombinant polymers
Price, R., Poursaid, A. E., & Ghandehari, H. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.06.016 · Cited by 57 · see citing works
Self-citationPradal, C., Jack, K. S., Grøndahl, L., & Cooper-White, J. J. (2013) · Biomacromolecules · doi:10.1021/bm401168h · Cited by 57 · see citing works
Delivery of a lentiviral vector in a Pluronic F127 gel to cells of the central nervous system
Strappe, P., Hampton, D. W., Cachón-González, B., FAWCETT, J., & Lever, A. M. L. (2005) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2005.06.006 · Cited by 57 · see citing works
Creel, H. S., Fournier, M. J., Mason, T. L., & Tirrell, D. A. (1991) · Macromolecules · doi:10.1021/ma00005a040 · Cited by 57 · see citing works
Gustafson, J. A., Price, R. A., Frandsen, J. L., Henak, C. R., Cappello, J., & Ghandehari, H. (2013) · Biomacromolecules · doi:10.1021/bm3013692 · Cited by 57 · see citing works
Self-citationBiodegradable Viral Nanoparticle/Polymer Implants Prepared via Melt-Processing
Lee, P. W., Shukla, S., Wallat, J. D., Danda, C., Steinmetz, N. F., Maia, J. M., & Pokorski, J. K. (2017) · ACS Nano · doi:10.1021/acsnano.7b02786 · Cited by 57 · see citing works
Lentivirus Immobilization to Nanoparticles for Enhanced and Localized Delivery From Hydrogels
Shin, S., & Shea, L. D. (2010) · Molecular Therapy · doi:10.1038/mt.2009.300 · Cited by 56 · see citing works
Local sustained delivery of oncolytic adenovirus with injectable alginate gel for cancer virotherapy
Choi, J.-W., Kang, E., Kwon, O.-J., Yun, T. J., Park, H.-K., Kim, P.-H., Kim, S., Kim, J. H., & Yun, C.-O. (2013) · Gene Therapy · doi:10.1038/gt.2013.10 · Cited by 55 · see citing works
Doel, M. T., Eaton, M. A. W., Cook, E. A., Lewis, H., Patel, T. P., & Carey, N. H. (1980) · Nucleic Acids Research · doi:10.1093/nar/8.20.4575 · Cited by 55 · see citing works
Greish, K. F., Frandsen, J. L., Scharff, S., Gustafson, J. A., Cappello, J., Li, D., O'Malley, B. W., & Ghandehari, H. (2010) · The Journal of Gene Medicine · doi:10.1002/jgm.1469 · Cited by 54 · see citing works
Self-citationLi, J., Xu, Q., Teng, B., Chen, Y., Li, J., Song, L., Lai, Y., Zhang, J. V., Zheng, W., & Ren, P. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.06.024 · Cited by 54 · see citing works
A Novel Method for Viral Gene Delivery in Solid Tumors
Wang, Y., Liu, S., Li, C., & Yuan, F. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1112 · Cited by 53 · see citing works
Poly-L-lysine improves gene transfer with adenovirus formulated in PLGA microspheres
Matthews, C. B., Jenkins, G., Hilfinger, J. M., & Davidson, B. L. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300978 · Cited by 51 · see citing works
Shepard, J. A., Virani, F. R., Goodman, A. G., Gossett, T. D., Shin, S., & Shea, L. D. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.06.081 · Cited by 50 · see citing works
Zhang, Y., Fan, W. Q., Nothdurft, L. D., Wu, C., Zhou, Y., Crawford, R., & Xiao, Y. (2011) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2010.0453 · Cited by 50 · see citing works
Price, R., Poursaid, A. E., Cappello, J., & Ghandehari, H. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.06.022 · Cited by 49 · see citing works
Self-citationThomas, A. M., & Shea, L. D. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.06.013 · Cited by 49 · see citing works
Bellocq, N. C., Kang, D. W., Wang, X., Jensen, G. S., Pun, S. H., Schluep, T., Zepeda, M. L., & Davis, M. E. (2004) · Bioconjugate Chemistry · doi:10.1021/bc0498119 · Cited by 47 · see citing works
Maillard, L., BELLE, E. V., Tio, F. O., Rivard, A., Kearney, M., Branellec, D., Steg, P. G., Isner, J. M., & Walsh, K. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301255 · Cited by 46 · see citing works
Madrigal, J. L., Sharma, S. N., Campbell, K. T., Stilhano, R. S., Gijsbers, R., & Silva, E. A. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.01.013 · Cited by 45 · see citing works
Thomas, A. M., Gomez, A., Palma, J. L., Yap, W. T., & Shea, L. D. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.06.027 · Cited by 44 · see citing works
Hwang, D., Moolchandani, V., Dandu, R., Haider, M. A., Cappello, J., & Ghandehari, H. (2008) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2008.10.021 · Cited by 43 · see citing works
Self-citationMok, H., Park, J. W., & Park, T. G. (2007) · Pharmaceutical Research · doi:10.1007/s11095-007-9441-y · Cited by 43 · see citing works
Optimization of a fibrin scaffold for sustained release of an adenoviral gene vector
Breen, A., Strappe, P., Kumar, A. C. V., O’Brien, T., & Pandit, A. S. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30735 · Cited by 41 · see citing works
Beer, S. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00022-7 · Cited by 41 · see citing works
Fibrin scaffold promotes adenoviral gene transfer and controlled vector delivery
Breen, A., Dockery, P., O’Brien, T., & Pandit, A. S. (2008) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32039 · Cited by 40 · see citing works
Price, R., Gustafson, J. A., Greish, K. F., Cappello, J., McGill, L. D., & Ghandehari, H. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.09.037 · Cited by 39 · see citing works
Self-citationZeng, Y., Tseng, S. ‐., Kempson, I. M., Peng, S., Wu, W., & Liu, J. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.09.018 · Cited by 38 · see citing works
Projection Stereolithographic Fabrication of BMP-2 Gene-activated Matrix for Bone Tissue Engineering
Lin, H., Tang, Y. M., Lozito, T. P., Oyster, N. M., Kang, R. B., Fritch, M. R., Wang, B., & Tuan, R. S. (2017) · Scientific Reports · doi:10.1038/s41598-017-11051-0 · Cited by 38 · see citing works
A PLG/HAp composite scaffold for lentivirus delivery
Boehler, R. M., Shin, S., Fast, A. G., Gower, R. M., & Shea, L. D. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.04.009 · Cited by 36 · see citing works
Fine structure of the vaccinia virion determined by controlled degradation and immunolocalization
Moussatché, N., & CONDIT, R. C. (2014) · Virology · doi:10.1016/j.virol.2014.11.020 · Cited by 35 · see citing works
Perreur, C., Habas, J., Peyrelasse, J., François, J., & Lapp, A. (2001) · Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics · doi:10.1103/physreve.63.031505 · Cited by 34 · see citing works
Voter, W. A., Lucaveche, C., & Erickson, H. (1986) · Biopolymers · doi:10.1002/bip.360251214 · Cited by 34 · see citing works
Rey‐Rico, A., Babicz, H., Madry, H., Concheiro, Á., Alvarez‐Lorenzo, C., & Cucchiarini, M. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.05.050 · Cited by 34 · see citing works
Celastrol enhances AAV1-mediated gene expression in mice adipose tissues
Zhang, F.-L., Jia, S.-Q., Zheng, S.-P., & Ding, W. (2011) · Gene Therapy · doi:10.1038/gt.2010.120 · Cited by 33 · see citing works
Díaz‐Rodríguez, P., Rey‐Rico, A., Madry, H., Landín, M., & Cucchiarini, M. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.11.008 · Cited by 33 · see citing works
Characterization of Structurally Related Adenovirus-laden Silk-elastinlike Hydrogels
Dandu, R., Ghandehari, H., & Cappello, J. (2007) · Journal of Bioactive and Compatible Polymers · doi:10.1177/0883911507085278 · Cited by 32 · see citing works
Self-citationCoacervate microspheres as carriers of recombinant adenoviruses
Kalyanasundaram, S., Feinstein, S., Nicholson, J. P., Leong, K. W., & Garver, R. I. (1999) · Cancer Gene Therapy · doi:10.1038/sj.cgt.7700025 · Cited by 32 · see citing works
Cresce, A. V. W., Dandu, R., Burger, A. M., Cappello, J., & Ghandehari, H. (2008) · Molecular Pharmaceutics · doi:10.1021/mp800054w · Cited by 31 · see citing works
Self-citationStooker, W., Niessen, H. W. M., Wildevuur, W. R., van Hinsbergh, V. W. M., Fritz, J., Jansen, E. K., Wildevuur, C. R. H., & Eijsman, L. (2002) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/s1010-7940(01)01121-6 · Cited by 31 · see citing works
Fibrin-mediated lentivirus gene transfer: Implications for lentivirus microarrays
Raut, S. D., Lei, P., Padmashali, R. M., & Andreadis, S. T. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.02.009 · Cited by 30 · see citing works
The development of a novel wound healing material, silk-elastin sponge
Kawabata, S., Kawai, K., Somamoto, S., Noda, K., Matsuura, Y., Nakamura, Y., & Suzuki, S. (2017) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2017.1382829 · Cited by 29 · see citing works
Price, R., Poursaid, A. E., Cappello, J., & Ghandehari, H. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.07.044 · Cited by 28 · see citing works
Self-citationDriessens, G., Nuttin, L., Gras, A., Maetens, J., Mievis, S., Schoore, M., Velu, T. J., Tenenbaum, L., Véronique Préat, A., & Bruyns, C. (2010) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-010-0941-y · Cited by 28 · see citing works
BONE INDUCTION BY ADBMP-2/COLLAGEN IMPLANTS
SCHREIBER, R. E., Blease, K., Ambrosio, A. M. A., Amburn, E., Sosnowski, B. A., & Sampath, T. K. (2005) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.d.02025 · Cited by 28 · see citing works
Polymers for viral gene delivery
Wang, C., & Pham, P.-T. T. (2008) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.5.4.385 · Cited by 27 · see citing works
Microfluidic generation of alginate microgels for the controlled delivery of lentivectors
Madrigal, J. L., Stilhano, R. S., Siltanen, C. A., Tanaka, K., Rezvani, S. N., Morgan, R. P., Revzin, A., Han, S. W., & Silva, E. A. (2016) · Journal of Materials Chemistry B · doi:10.1039/c6tb02150f · Cited by 25 · see citing works
Tseng, S. ‐., Kempson, I. M., Peng, S., Ke, B.-H., Chen, H., Chen, P., & Hwu, Y. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.05.009 · Cited by 24 · see citing works
Sponge-mediated lentivirus delivery to acute and chronic spinal cord injuries
Thomas, A. M., Palma, J. L., & Shea, L. D. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.02.032 · Cited by 24 · see citing works
del Barrio, G. G., Hendry, J., Renedo, M. J., Irache, J. M., & Novo, F. J. (2003) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.10.011 · Cited by 23 · see citing works
Wan, L., Li, D., & Wu, Q. (2006) · Journal of Surgical Research · doi:10.1016/j.jss.2006.02.056 · Cited by 20 · see citing works
ADVENTITIAL GENE TRANSFER TO ARTERIAL WALL
Laitinen, M., & Ylä‐Herttuala, S. (1998) · Pharmacological Research · doi:10.1006/phrs.1998.0296 · Cited by 19 · see citing works
Jung, S., Choi, J., Yun, C., Yhee, J. Y., Price, R., Kim, S. H., Kwon, I. C., & Ghandehari, H. (2014) · The Journal of Gene Medicine · doi:10.1002/jgm.2770 · Cited by 18 · see citing works
Self-citationDíaz‐Rodríguez, P., & Landín, M. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.01.021 · Cited by 16 · see citing works
Xue, J., Lin, H., Bean, A., Tang, Y. M., Tan, J., Tuan, R. S., & Wang, B. (2017) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2017.08.008 · Cited by 16 · see citing works
Peterson, C. Y., Shaterian, A., Borboa, A. K., Gonzalez, A. M., Potenza, B. M., Coimbra, R. S. M., Eliceiri, B. P., & Baird, A. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.07.069 · Cited by 15 · see citing works
Hen, G., Yosefi, S., Shinder, D., Or, A., Mygdal, S., Condiotti, R., Galun, E., Bor, A., Sela‐Donenfeld, D., & Friedman‐Einat, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036531 · Cited by 15 · see citing works
Teraishi, F., Umeoka, T., Saito, T., Tsukagoshi, T., Tanaka, N., & Fujiwara, T. (2003) · Surgical Endoscopy · doi:10.1007/s00464-003-8146-5 · Cited by 15 · see citing works
Schmidt, C. A., Bezuidenhout, D., Zilla, P., & Davies, N. H. (2013) · Journal of Biomaterials Applications · doi:10.1177/0885328213510331 · Cited by 15 · see citing works
Localized lentivirus delivery via peptide interactions
Skoumal, M., Seidlits, S. K., Shin, S., & Shea, L. D. (2016) · Biotechnology and Bioengineering · doi:10.1002/bit.25961 · Cited by 15 · see citing works
Silk-elastin-like protein polymer matrix for intraoperative delivery of an oncolytic vaccinia virus
Price, D. L., Li, P., Chen, C., Wong, D., Yu, Z., Chen, N. G., Yu, Y., Szalay, A. A., Cappello, J., Fong, Y., et al. (2014) · Head & Neck · doi:10.1002/hed.23877 · Cited by 11 · see citing works
Gonzalez, A. M., Berlanga, O., Leadbeater, W. E., Cooper‐Charles, L., Sims, K., Logan, A., Eliceiri, B. P., Berry, M., & Baird, A. (2009) · The Journal of Gene Medicine · doi:10.1002/jgm.1354 · Cited by 10 · see citing works
XIA, D., FENG, L.-B., Wu, X., Xia, G., & Xu, L. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3578 · Cited by 6 · see citing works
Christopher, J., Dinjaski, N., Auxiliadora, P. M., & Andr�s, G. (2016) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/conf.fbioe.2016.01.01903 · Cited by 5 · see citing works
Jung, S., Choi, J.-W., Yun, C., Kim, S. H., Kwon, I. C., & Ghandehari, H. (2015) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.5b00075 · Cited by 5 · see citing works
Self-citationXia, D., Yao, H., Liu, Q., & Xu, L. (2012) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2012.13.12.6363 · Cited by 3 · see citing works
Lubaroff, D. M., Vaena, D. A., Brown, J. A., Nepple, K. G., Zehr, P. S., Griffith, K. C., Brown, E. D., Eastman, J., Zamba, G. K. D., & Williams, R. D. (2015) · Cancer Research · doi:10.1158/1538-7445.am2015-ct208 · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
PROTAC targeted protein degraders: the past is prologue
Békés, M., Langley, D. R., & Crews, C. M. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00371-6 · Cited by 3,395 · see citing works
Polymeric Delivery of Therapeutic Nucleic Acids
Kumar, R., Chalarca, C. F. S., Bockman, M. R., Bruggen, C. V., Grimme, C. J., Dalal, R. J., Hanson, M. G., Hexum, J. K., & Reineke, T. M. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00997 · Cited by 370 · see citing works
Materials promoting viral gene delivery
Kaygisiz, K., & Synatschke, C. V. (2020) · Biomaterials Science · doi:10.1039/d0bm01367f · Cited by 56 · see citing works
Biopolymers: a comprehensive review of sustainability, environmental impact, and lifecycle analysis
Kogje, M., Satdive, A. M., Mestry, S. U., & Mhaske, S. T. (2025) · Iranian Polymer Journal · doi:10.1007/s13726-024-01449-9 · Cited by 28 · see citing works
Conjugated Polymers for Gene Delivery and Photothermal Gene Expression
Song, G., Lv, F., Huang, Y., Bai, H., & Wang, S. (2022) · ChemPlusChem · doi:10.1002/cplu.202200073 · Cited by 19 · see citing works
Pennetta, C., Bono, N., Ponti, F., Bellucci, M. C., Viani, F., Candiani, G., & Volonterio, A. (2021) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.0c00616 · Cited by 18 · see citing works
Hatlevik, Ø., Jensen, M., Steinhauff, D. B., Wei, X., Huo, E. J., Jedrzkiewicz, J., Cappello, J., Cheney, D. L., & Ghandehari, H. (2022) · Macromolecular Bioscience · doi:10.1002/mabi.202100401 · Cited by 10 · see citing works
Self-citationSteinhauff, D. B., Jensen, M. M., Griswold, E. D., Jedrzkiewicz, J., Cappello, J., Oottamasathien, S., & Ghandehari, H. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14010175 · Cited by 4 · see citing works
Self-citationMulti-compartment containers from a mixture of natural and synthetic lipids
Yaroslavov, A. A., Ефимова, А. А., Abramova, T. A., Pozdyshev, D. V., & Muronetz, V. I. (2023) · Mendeleev Communications · doi:10.1016/j.mencom.2023.02.023 · Cited by 4 · see citing works
Genetically-encoded degraders as versatile modulators of intracellular therapeutic targets
Dai, C., Wang, J., Tu, L., Pan, Z., Yang, J., Zhou, S. Y., Luo, Q., Zhu, L., & Ye, Y. (2023) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2023.100458
Encapsulation of natural materials
Hancox, Z., Nisar, A., & Sefat, F. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-824345-9.00020-9
Hydrogels as nucleic acid therapeutics
Sánchez-Castillo, L. V., Tsekoura, E. K., & Narain, R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-16168-1.00015-5
Peri-Implantation Targeting Using Modified Adenoviral Vectors
Serejnikova, N. B., Fayzullin, A. L., Antoshin, A. A., Timakova, A., Иванова, Е., Ershov, B. P., Файзуллина, Н. М., Ulasov, I. V., Malogolovkin, A. S., Kotova, S., et al. (2025) · Journal of Anatomy and Histopathology · doi:10.18499/2225-7357-2024-13-4-61-74
Polysaccharides Based on Smart Chitosan Nanoparticles for Gene Delivery and Gene Therapy
Naghib, S. M. (2025) · Series in bioengineering · doi:10.1007/978-981-95-1888-3_10
Agasti, S., Jain, E., & Mishra, R. (2026) · Polymers for Advanced Technologies · doi:10.1002/pat.70757
- Authors
- Steinhauff, D., & Ghandehari, H.
- Affiliations
- University of Utah (US)
- Utah Center for Nanomedicine, Nano Institute of Utah, 36 South Wasatch Drive, Salt Lake City, Utah 84112, United States
- Corresponding author
- Ghandehari, Hamidreza
- Venue
- Bioconjugate Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2019-02-01
- Volume
- 30
- Issue
- 2
- Pages
- 384-399
- ISSN
- 1043-1802 (ISSN-L)
- 1520-4812
- OpenAlex
- W2915044621
- Cited by
- 15
- References
- 194
- Citations by year
- 2026: 1 · 2025: 4 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 1
- FWCI
- 0.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Bioconjugate Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (R01 CA107621, RO1CA227225)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Virus-based gene therapy research
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Keywords
- viral gene delivery, polymer matrix, viral vectors, polymeric nanoparticles, immune evasion, natural polymers, synthetic polymers, regenerative medicine, cancer therapy
- MeSH terms
- Animals, Gels, Genetic Vectors, Humans, Polymers, Viruses, Gene Transfer Techniques
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review