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Cited by 667

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications

Open access
Karimi-Jafari, Maryam, Padrela, Luis, Walker, Gavin M., Croker, Denise M.·2018·Crystal Growth & Design
DOI 10.1021/acs.cgd.8b00933
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Abstract

Abstract Originally discovered almost a century ago, cocrystals continue to gain interest in the modern day due to their ability to modify the physical properties of solid-state materials, particularly pharmaceuticals. Intensification of cocrystal research efforts has been accompanied by an expansion of the potential applications where cocrystals can offer a benefit. Where once solubility manipulation was seen as the primary driver for cocrystal formation, cocrystals have recently been shown to provide attractive options for taste masking, mechanical property improvement, and intellectual property generation and extension. Cocrystals are becoming a commercial reality with a number of cocrystal products currently on the market and more following in registration and clinical trial phases. Increased commercialization of cocrystals has in turn necessitated additional research on methods to make cocrystals, with particular emphasis placed on emerging technologies that can offer environmentally attractive and efficient options. Methods of producing cocrystals and of harnessing the bespoke physical property adjustment provided by cocrystals are reviewed in this article, with a particular focus on emerging trends in these areas.

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Crossref · 10.1021/acs.cgd.8b00933

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Metadata

Authors
Karimi-Jafari, M., Padrela, L., Walker, G. M., & Croker, D. M.
Venue
Crystal Growth & Design
Publisher
American Chemical Society (ACS)
Published
2018-08-10
Volume
18
Issue
10
Pages
6370-6387
ISSN
  • 1528-7483 (ISSN-L)
  • 1528-7505
DOI
10.1021/acs.cgd.8b00933
OpenAlex
W2886419664
Cited by
667
References
50
FWCI
36.64
Type
journal article
Language
en
Open access
hybrid

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.