The DOI matches its Crossref record; 210 of the 210 references it cites were found in a registry or an index.
Engineered Hemostatic Biomaterials for Sealing Wounds
Abstract
Hemostatic biomaterials show great promise in wound control for the treatment of uncontrolled bleeding associated with damaged tissues, traumatic wounds, and surgical incisions. A surge of interest has been directed at boosting hemostatic properties of bioactive materials via mechanisms triggering the coagulation cascade. A wide variety of biocompatible and biodegradable materials has been applied to the design of hemostatic platforms for rapid blood coagulation. Recent trends in the design of hemostatic agents emphasize chemical conjugation of charged moieties to biomacromolecules, physical incorporation of blood-coagulating agents in biomaterials systems, and superabsorbing materials in either dry (foams) or wet (hydrogel) states. In addition, tough bioadhesives are emerging for efficient and physical sealing of incisions. In this Review, we highlight the biomacromolecular design approaches adopted to develop hemostatic bioactive materials. We discuss the mechanistic pathways of hemostasis along with the current standard experimental procedures for characterization of the hemostasis efficacy. Finally, we discuss the potential for clinical translation of hemostatic technologies, future trends, and research opportunities for the development of next-generation surgical materials with hemostatic properties for wound management.
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Cites
Functional Hydrogels as Wound Dressing to Enhance Wound Healing
Liang, Y., He, J., & Guo, B. (2021) · ACS Nano · doi:10.1021/acsnano.1c04206 · Cited by 3,135
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Dry double-sided tape for adhesion of wet tissues and devices
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Haemostatic materials for wound healing applications
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Cited by
Design of biopolymer-based hemostatic material: Starting from molecular structures and forms
Zou, C.-Y., Li, Q.-J., Hu, J.-J., Song, Y.-T., Zhang, Q.-Y., Nie, R., Li-Ling, J., & Xie, H.-Q. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100468 · Cited by 87
Lei, X., Zou, C., Hu, J., Fan, M., Jiang, Y., Xiong, M., Han, C., Zhang, X., Li, Y., Zhao, L., et al. (2024) · Advanced Science · doi:10.1002/advs.202306289 · Cited by 70
Li, S., Dou, W., Zhu, S., Zeng, X., Ji, W., Li, X., Chen, N., Li, Y., Liu, C., Fan, H., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.133655 · Cited by 6
Metadata
- Authors
- Montazerian, H., Davoodi, E., Baidya, A., Baghdasarian, S., Sarikhani, E., Meyer, C. E., Haghniaz, R., Badv, M., Annabi, N., Khademhosseini, A., & Weiss, P. S.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2022-06-22
- Volume
- 122
- Issue
- 15
- Pages
- 12864-12903
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W4283274448
- Cited by
- 291
- References
- 210
- FWCI
- 14.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Montazerian, H., Davoodi, E., Baidya, A., Baghdasarian, S., Sarikhani, E., Meyer, C. E., Haghniaz, R., Badv, M., Annabi, N., Khademhosseini, A., & Weiss, P. S. (2022). Engineered Hemostatic Biomaterials for Sealing Wounds. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.1c01015
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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