Cited by 120Spectroscopy and Quantum Chemical StudiesPhotosynthetic Processes and MechanismsPhotochemistry and Electron Transfer Studies

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Single-Molecule Fluorescence Spectroscopy of Photosynthetic Systems

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Kondo, Toru, Chen, Wei Jia, Schlau-Cohen, Gabriela S.·2017·Chemical Reviews

DOI 10.1021/acs.chemrev.6b00195

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Abstract

Photosynthesis begins when a network of pigment-protein complexes captures solar energy and transports it to the reaction center, where charge separation occurs. When necessary (under low light conditions), photosynthetic organisms perform this energy transport and charge separation with near unity quantum efficiency. Remarkably, this high efficiency is maintained under physiological conditions, which include thermal fluctuations of the pigment-protein complexes and changing local environments. These conditions introduce multiple types of heterogeneity in the pigment-protein complexes, including structural heterogeneity, energetic heterogeneity, and functional heterogeneity. Understanding how photosynthetic light-harvesting functions in the face of these fluctuations requires understanding this heterogeneity, which, in turn, requires characterization of individual pigment-protein complexes. Single-molecule spectroscopy has the power to probe individual complexes. In this review, we present an overview of the common techniques for single-molecule fluorescence spectroscopy applied to photosynthetic systems and describe selected experiments on these systems. We discuss how these experiments provide a new understanding of the impact of heterogeneity on light harvesting and thus how these systems are optimized to capture sunlight under physiological conditions.

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1 retracted

RETRACTED: Fluorescence Spectroscopy of Conformational Changes of Single LH2 Complexes
Rutkauskas, D., Novoderezhkin, V. I., Cogdell, R. J., & van Grondelle, R. (2004) · Biophysical Journal · doi:10.1529/biophysj.104.048629 · Cited by 85
Retracted
Encyclopedia of Analytical Chemistry
Grochocki, W., Markuszewski, M., & Quirino, J. P. (2006) · Wiley eBooks · doi:10.1002/9780470027318 · Cited by 7,503
Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy
Hell, S. W., & Wichmann, J. (1994) · Optics Letters · doi:10.1364/ol.19.000780 · Cited by 6,068
Determination of accurate extinction coefficients and simultaneous equations for assaying chlorophylls a and b extracted with four different solvents: verification of the concentration of chlorophyll standards by atomic absorption spectroscopy
Porra, R. J., Thompson, W. A., & Kriedemann, P. E. (1989) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(89)80347-0 · Cited by 6,013
Principles of Fluorescence Spectroscopy
Lakowicz, J. R. (1983) · Springer eBooks · doi:10.1007/978-1-4615-7658-7 · Cited by 5,093
Three-dimensional structure of cyanobacterial photosystem I at 2.5 Å resolution
Jordan, P., Fromme, P., Witt, H. T., Klukas, O., Saenger, W., & Krauß, N. (2001) · Nature · doi:10.1038/35082000 · Cited by 2,494
A practical guide to single-molecule FRET
Roy, R., Hohng, S., & Ha, T. (2008) · Nature Methods · doi:10.1038/nmeth.1208 · Cited by 2,174
Handbook of Photovoltaic Science and Engineering
(2003) · Wiley eBooks · doi:10.1002/0470014008 · Cited by 2,060
Towards complete cofactor arrangement in the 3.0 Å resolution structure of photosystem II
Loll, B., Kern, J. F., Saenger, W., Zouni, A., & Biesiadka, J. (2005) · Nature · doi:10.1038/nature04224 · Cited by 1,867
Near-Field Optics: Microscopy, Spectroscopy, and Surface Modification Beyond the Diffraction Limit
Betzig, E., & Trautman, J. K. (1992) · Science · doi:10.1126/science.257.5067.189 · Cited by 1,810
Thermodynamic Fluctuations in a Reacting System—Measurement by Fluorescence Correlation Spectroscopy
Magde, D., Elson, E. L., & Webb, W. W. (1972) · Physical Review Letters · doi:10.1103/physrevlett.29.705 · Cited by 1,783
Crystal structure of spinach major light-harvesting complex at 2.72 Å resolution
Liu, Z., Yan, H., Wang, K., Kuang, T., Zhang, J., Gui, L.-L., An, X., & Chang, W. (2004) · Nature · doi:10.1038/nature02373 · Cited by 1,708
A Test of a New Type of Stellar Interferometer on Sirius
Brown, R. H., & Twiss, R. Q. (1956) · Nature · doi:10.1038/1781046a0 · Cited by 1,562
Fluorescence correlation spectroscopy. I. Conceptual basis and theory
Elson, E. L., & Magde, D. (1974) · Biopolymers · doi:10.1002/bip.1974.360130102 · Cited by 1,456
Invited Review Article: Single-photon sources and detectors
Eisaman, M. D., Fan, J., Migdall, A., & Polyakov, S. V. (2011) · Review of Scientific Instruments · doi:10.1063/1.3610677 · Cited by 1,358
Membrane proteins, lipids and detergents: not just a soap opera
Seddon, A. M., Curnow, P., & Booth, P. J. (2004) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2004.04.011 · Cited by 1,340
Optical detection and spectroscopy of single molecules in a solid
Moerner, W. E., & Kador, L. (1989) · Physical Review Letters · doi:10.1103/physrevlett.62.2535 · Cited by 1,273
Single Molecules Observed by Near-Field Scanning Optical Microscopy
Betzig, E., & Chichester, R. J. (1993) · Science · doi:10.1126/science.262.5138.1422 · Cited by 1,266
Carotenoids in Photosynthesis
Frank, H. A., & Cogdell, R. J. (1996) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1996.tb03022.x · Cited by 1,201
Temperature-dependent X-ray diffraction as a probe of protein structural dynamics
Frauenfelder, H., Petsko, G. A., & Tsernoglou, D. (1979) · Nature · doi:10.1038/280558a0 · Cited by 1,151
Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution
Funatsu, T., Harada, Y., Tokunaga, M., Saito, K., & Yanagida, T. (1995) · Nature · doi:10.1038/374555a0 · Cited by 1,048
Single pentacene molecules detected by fluorescence excitation in a p -terphenyl crystal
Orrit, M., & Bernard, J. (1990) · Physical Review Letters · doi:10.1103/physrevlett.65.2716 · Cited by 1,040
Natural strategies for photosynthetic light harvesting
Croce, R., & van Amerongen, H. (2014) · Nature Chemical Biology · doi:10.1038/nchembio.1555 · Cited by 1,013
Photosynthetic Excitons
van Amerongen, H., van Grondelle, R., & Valkūnas, L. (2000) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789812813664 · Cited by 990
Generalized Two-Dimensional Correlation Spectroscopy
Noda, I., Dowrey, A. E., Marcott, C. A., Story, G. M., & Ozaki, Y. (2000) · Applied Spectroscopy · doi:10.1366/0003702001950454 · Cited by 938
Current Protocols in Cytometry
(2001) · John Wiley & Sons, Inc. eBooks · doi:10.1002/0471142956 · Cited by 918
Methods of single-molecule fluorescence spectroscopy and microscopy
Moerner, W. E., & Fromm, D. P. (2003) · Review of Scientific Instruments · doi:10.1063/1.1589587 · Cited by 888
Molecular Mechanisms of Photosynthesis
Youvan, D. C., & Marrs, B. L. (1987) · Scientific American · doi:10.1038/scientificamerican0687-42 · Cited by 850
An Oxygen Scavenging System for Improvement of Dye Stability in Single-Molecule Fluorescence Experiments
Aitken, C. E., Marshall, R. A., & Puglisi, J. D. (2007) · Biophysical Journal · doi:10.1529/biophysj.107.117689 · Cited by 846
XXXVIII.A suggested method for extending microscopic resolution into the ultra-microscopic region
Synge, E. H. (1928) · The London Edinburgh and Dublin Philosophical Magazine and Journal of Science · doi:10.1080/14786440808564615 · Cited by 845
Cell-substrate contacts illuminated by total internal reflection fluorescence.
Axelrod, D. (1981) · The Journal of Cell Biology · doi:10.1083/jcb.89.1.141 · Cited by 838
Protein states and proteinquakes.
Ansari, A., Berendzen, J., Bowne, S. F., Frauenfelder, H., Iben, I. E., Sauke, T. B., Shyamsunder, E., & Young, R. D. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.15.5000 · Cited by 828
Scanning near-field optical microscopy with aperture probes: Fundamentals and applications
Hecht, B., Sick, B., Wild, U. P., Deckert, V., Zenobi, R., Martin, O. J. F., & Pohl, D. (2000) · The Journal of Chemical Physics · doi:10.1063/1.481382 · Cited by 764
The photoprotective molecular switch in the photosystem II antenna
Ruban, A. V., Johnson, M. P., & Duffy, C. D. P. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2011.04.007 · Cited by 750
Total Internal Reflection Fluorescence
Axelrod, D., Burghardt, T. P., & Thompson, N. L. (1984) · Annual Review of Biophysics and Bioengineering · doi:10.1146/annurev.bb.13.060184.001335 · Cited by 742
How Proteins Trigger Excitation Energy Transfer in the FMO Complex of Green Sulfur Bacteria
Adolphs, J., & Renger, T. (2006) · Biophysical Journal · doi:10.1529/biophysj.105.079483 · Cited by 696
Photophysics of Fluorescent Probes for Single-Molecule Biophysics and Super-Resolution Imaging
Ha, T., & Tinnefeld, P. (2012) · Annual Review of Physical Chemistry · doi:10.1146/annurev-physchem-032210-103340 · Cited by 692
The architecture and function of the light-harvesting apparatus of purple bacteria: from single molecules to in vivo membranes
Cogdell, R. J., Gall, A., & Köhler, J. R. (2006) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583506004434 · Cited by 689
Lateral heterogeneity in the distribution of chlorophyll-protein complexes of the thylakoid membranes of spinach chloroplasts
Andersson, B., & Anderson, J. M. (1980) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(80)90078-x · Cited by 682
Photobleaching kinetics of fluorescein in quantitative fluorescence microscopy
Song, L., Hennink, E. J., Young, I. T., & Tanke, H. J. (1995) · Biophysical Journal · doi:10.1016/s0006-3495(95)80442-x · Cited by 658
Crystal Structure of the RC-LH1 Core Complex from Rhodopseudomonas palustris
Roszak, A. W., Howard, T. D., Southall, J., Gardiner, A. T., Law, C. J., Isaacs, N. W., & Cogdell, R. J. (2003) · Science · doi:10.1126/science.1088892 · Cited by 625
Advances in photosynthesis and respiration
Sharkey, T. D. (2012) · Photosynthesis Research · doi:10.1007/s11120-012-9722-0 · Cited by 609
Optical properties of disordered molecular aggregates: A numerical study
Fidder, H., Knoester, J., & Wiersma, D. A. (1991) · The Journal of Chemical Physics · doi:10.1063/1.461317 · Cited by 595
Single-particle electron cryo-microscopy: towards atomic resolution
van Heel, M., Gowen, B. E., Matadeen, R., Orlova, E. V., Finn, R. D., Pape, T., Cohen, D. R., Stark, H., Schmidt, R., Schatz, M. X., et al. (2000) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583500003644 · Cited by 583
Discrete Cyclic Porphyrin Arrays as Artificial Light-Harvesting Antenna
Aratani, N., Kim, D., & Osuka, A. (2009) · Accounts of Chemical Research · doi:10.1021/ar9001697 · Cited by 558
Probing Individual Molecules with Confocal Fluorescence Microscopy
Nie, S., Chiu, D. T.-Y., & Zare, R. N. (1994) · Science · doi:10.1126/science.7973650 · Cited by 551
Video-rate nanoscopy using sCMOS camera–specific single-molecule localization algorithms
Huang, F., Hartwich, T. M. P., Rivera-Molina, F. E., Lin, Y., Duim, W. C., Long, J. J., Uchil, P. D., Myers, J. R., Baird, M. A., Mothes, W., et al. (2013) · Nature Methods · doi:10.1038/nmeth.2488 · Cited by 531
Unraveling the Electronic Structure of Individual Photosynthetic Pigment-Protein Complexes
van Oijen, A. M., Ketelaars, M., Köhler, J. R., Aartsma, T. J., & Schmidt, J. (1999) · Science · doi:10.1126/science.285.5426.400 · Cited by 530
Evolution of flexible non-photochemical quenching mechanisms that regulate light harvesting in oxygenic photosynthesis
Niyogi, K., & Truong, T. B. (2013) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2013.03.011 · Cited by 501
The structure of a plant photosystem I supercomplex at 3.4 Å resolution
Amunts, A., Drory, O., & Nelson, N. (2007) · Nature · doi:10.1038/nature05687 · Cited by 490
The Structure and Thermal Motion of the B800–850 LH2 Complex from Rps.acidophila at 2.0Å Resolution and 100K: New Structural Features and Functionally Relevant Motions
Papiz, M. Z., Prince, S. M., Howard, T. D., Cogdell, R. J., & Isaacs, N. W. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00024-x · Cited by 489
Detection of single fluorescent molecules
Shera, E. B., Seitzinger, N. K., Davis, L. M., Keller, R. A., & Soper, S. A. (1990) · Chemical Physics Letters · doi:10.1016/0009-2614(90)85485-u · Cited by 477
Structural basis for energy transfer pathways in the plant PSI-LHCI supercomplex
Qin, X., Suga, M., Kuang, T., & Shen, J. (2015) · Science · doi:10.1126/science.aab0214 · Cited by 466
Statistical accuracy in fluorescence correlation spectroscopy
Koppel, D. E. (1974) · Physical Review A · doi:10.1103/physreva.10.1938 · Cited by 456
Beyond Förster Resonance Energy Transfer in Biological and Nanoscale Systems
Beljonne, D., Curutchet, C., Scholes, G. D., & Silbey, R. (2009) · The Journal of Physical Chemistry B · doi:10.1021/jp900708f · Cited by 452
On the adequacy of the Redfield equation and related approaches to the study of quantum dynamics in electronic energy transfer
Ishizaki, A., & Fleming, G. R. (2009) · The Journal of Chemical Physics · doi:10.1063/1.3155214 · Cited by 430
Bioinspired Molecular Design of Light‐Harvesting Multiporphyrin Arrays
Choi, M., Yamazaki, T., Yamazaki, I., & Aida, T. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200301665 · Cited by 412
Triggered Source of Single Photons based on Controlled Single Molecule Fluorescence
Brunel, C., Lounis, B., Tamarat, P., & Orrit, M. (1999) · Physical Review Letters · doi:10.1103/physrevlett.83.2722 · Cited by 408
Superradiance and Exciton Delocalization in Bacterial Photosynthetic Light-Harvesting Systems
Monshouwer, R., Abrahamsson, M. L. A., van Mourik, F., & van Grondelle, R. (1997) · The Journal of Physical Chemistry B · doi:10.1021/jp963377t · Cited by 407
Light stress and photoprotection inChlamydomonas reinhardtii
Erickson, E., Wakao, S., & Niyogi, K. (2015) · The Plant Journal · doi:10.1111/tpj.12825 · Cited by 390
Candidatus Chloracidobacterium thermophilum: An Aerobic Phototrophic Acidobacterium
Bryant, D. A., Costas, A. M. G., Maresca, J. A., Chew, A. G. M., Klatt, C. G., Bateson, M. M., Tallon, L. J., Hostetler, J. B., Nelson, W. C., Heidelberg, J. F., et al. (2007) · Science · doi:10.1126/science.1143236 · Cited by 378
Integration of Photosynthetic Protein Molecular Complexes in Solid-State Electronic Devices
Das, R., Kiley, P. J., Segal, M., Norville, J. E., Yu, A. A., Wang, L., Trammell, S. A., Reddick, L. E., Kumar, R., Stellacci, F., et al. (2004) · Nano Letters · doi:10.1021/nl049579f · Cited by 368
An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent
Beatty, J. T., Overmann, J., Lince, M. T., Manske, A. K., Lang, A. S., Blankenship, R. E., Dover, C. L. V., Martinson, T. A., & Plumley, F. G. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503674102 · Cited by 368
Rotational brownian motion and fluorescence intensify fluctuations
Ehrenberg, M., & Rigler, R. W. (1974) · Chemical Physics · doi:10.1016/0301-0104(74)85005-6 · Cited by 367
Chlorophyll Organization and Function in Green Photosynthetic Bacteria*
Olson, J. M. (1998) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1998.tb05166.x · Cited by 355
Quantum Coherent Energy Transfer over Varying Pathways in Single Light-Harvesting Complexes
Hildner, R., Brinks, D., Nieder, J. B., Cogdell, R. J., & van Hulst, N. F. (2013) · Science · doi:10.1126/science.1235820 · Cited by 351
Detection and spectroscopy of single pentacene molecules in a p-terphenyl crystal by means of fluorescence excitation
Ambrose, W. P., Basché, T., & Moerner, W. E. (1991) · The Journal of Chemical Physics · doi:10.1063/1.461392 · Cited by 351
Quantum coherence and its interplay with protein environments in photosynthetic electronic energy transfer
Ishizaki, A., Calhoun, T. R., Schlau‐Cohen, G. S., & Fleming, G. R. (2010) · Physical Chemistry Chemical Physics · doi:10.1039/c003389h · Cited by 350
Self-citation
Optical detection of magnetic resonance in a single molecule
Wrachtrup, J., von Borczyskowski, C., Bernard, J., Orrit, M., & Brown, R. (1993) · Nature · doi:10.1038/363244a0 · Cited by 347
Ten Years of Single-Molecule Spectroscopy
Tamarat, P., Maali, A., Lounis, B., & Orrit, M. (1999) · The Journal of Physical Chemistry A · doi:10.1021/jp992505l · Cited by 340
Detection of Intensity Change Points in Time-Resolved Single-Molecule Measurements
Watkins, L. P., & Yang, H. (2004) · The Journal of Physical Chemistry B · doi:10.1021/jp0467548 · Cited by 340
The noise performance of electron multiplying charge-coupled devices
Robbins, M. S., & Hadwen, B. (2003) · IEEE Transactions on Electron Devices · doi:10.1109/ted.2003.813462 · Cited by 330
Evolution and prospects for single-photon avalanche diodes and quenching circuits
Cova, S., Ghioni, M., Lotito, A., Rech, I., & Zappa, F. (2004) · Journal of Modern Optics · doi:10.1080/09500340408235272 · Cited by 321
Single Molecule Imaging of Fluorophores and Enzymatic Reactions Achieved by Objective-Type Total Internal Reflection Fluorescence Microscopy
Tokunaga, M., Kitamura, K., Saito, K., Iwane, A. H., & Yanagida, T. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6732 · Cited by 310
Power-law intermittency of single emitters
Cichos, F., von Borczyskowski, C., & Orrit, M. (2007) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2007.07.012 · Cited by 307
Alternating syn-anti bacteriochlorophylls form concentric helical nanotubes in chlorosomes
Ganapathy, S., Oostergetel, G. T., Wawrzyniak, P., Reus, M., Chew, A. G. M., Buda, F., Boekema, E. J., Bryant, D. A., Holzwarth, A. R., & de Groot, H. J. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903534106 · Cited by 305
Magnetic resonance of a single molecular spin
Köhler, J. R., Disselhorst, J. A. J. M., Donckers, M. C. J. M., Groenen, E. J. J., Schmidt, J., & Moerner, W. E. (1993) · Nature · doi:10.1038/363242a0 · Cited by 288
Chromatic Adaptation of Photosynthetic Membranes
Simon Scheuring, A., & Sturgis, J. N. (2005) · Science · doi:10.1126/science.1110879 · Cited by 281
Lighting up the cell surface with evanescent wave microscopy
Toomre, D. K., & Manstein, D. J. (2001) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02027-x · Cited by 279
Chemomechanical coupling in F1-ATPase revealed by simultaneous observation of nucleotide kinetics and rotation
Nishizaka, T., Oiwa, K., Noji, H., Kimura, S., Muneyuki, E., Yoshida, M., & Kinosita, K. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb721 · Cited by 276
Method for trapping and manipulating nanoscale objects in solution
Cohen, A. E., & Moerner, W. E. (2005) · Applied Physics Letters · doi:10.1063/1.1872220 · Cited by 258
Concentration quenching in chlorophyll
Beddard, G. S., & Porter, G. (1976) · Nature · doi:10.1038/260366a0 · Cited by 257
An Experimental Comparison of the Maximum Likelihood Estimation and Nonlinear Least-Squares Fluorescence Lifetime Analysis of Single Molecules
Maus, M., Cotlet, M., Hofkens, J., Gensch, T., Schryver, F. C. D., Schaffer, J., & Seidel, C. A. M. (2001) · Analytical Chemistry · doi:10.1021/ac000877g · Cited by 257
SINGLE-MOLECULE OPTICS
Kulzer, F., & Orrit, M. (2004) · Annual Review of Physical Chemistry · doi:10.1146/annurev.physchem.54.011002.103816 · Cited by 254
Physiology and Phylogeny of Green Sulfur Bacteria Forming a Monospecific Phototrophic Assemblage at a Depth of 100 Meters in the Black Sea
Manske, A. K., Glaeser, J., Kuypers, M. M. M., & Overmann, J. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.8049-8060.2005 · Cited by 243
The chlorosome: a prototype for efficient light harvesting in photosynthesis
Oostergetel, G. T., van Amerongen, H., & Boekema, E. J. (2010) · Photosynthesis Research · doi:10.1007/s11120-010-9533-0 · Cited by 239
Fluorescence and photobleaching dynamics of single light-harvesting complexes
Bopp, M. A., Jia, Y., Li, L., Cogdell, R. J., & Hochstrasser, R. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.20.10630 · Cited by 236
Nanodissection and high-resolution imaging of the Rhodopseudomonas viridis photosynthetic core complex in native membranes by AFM
Simon Scheuring, A., Seguin, J., Marco, S., Lévy, D., Robert, B., & Rigaud, J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0437992100 · Cited by 235
Micromachining tools and correlative approaches for cellular cryo-electron tomography
Rigort, A., Bäuerlein, F. J. B., Leis, A. P., Gruska, M., Hoffmann, C., Laugks, T., Boehm, U., Eibauer, M., Gnaegi, H., Baumeister, W. P., et al. (2010) · Journal of Structural Biology · doi:10.1016/j.jsb.2010.02.011 · Cited by 234
Spectral hole-burning spectroscopy in amorphous molecular solids and proteins
Jankowiak, R., Hayes, J. M., & Small, G. J. (1993) · Chemical Reviews · doi:10.1021/cr00020a005 · Cited by 231
Lamellar Organization of Pigments in Chlorosomes, the Light Harvesting Complexes of Green Photosynthetic Bacteria
Pšenčı́k, J., Ikonen, T. P., Laurinmäki, P., Merckel, M. C., Butcher, S. J., Serimaa, R. E., & Tůma, R. (2004) · Biophysical Journal · doi:10.1529/biophysj.104.040956 · Cited by 227
Photobleaching of Rhodamine 6G in Poly(vinyl alcohol) at the Ensemble and Single-Molecule Levels
Zondervan, R., Kulzer, F., Kol'chenk, M. A., & Orrit, M. (2004) · The Journal of Physical Chemistry A · doi:10.1021/jp037222e · Cited by 224
Photobleaching and stabilization of. fluorophores used for single-molecule analysis. with one- and two-photon excitation
Dittrich, P. S., & Schwille, P. (2001) · Applied Physics B · doi:10.1007/s003400100737 · Cited by 223
Light and oxygenic photosynthesis: energy dissipation as a protection mechanism against photo‐oxidation
Szabó, I., Bergantino, E., & Giacometti, G. M. (2005) · EMBO Reports · doi:10.1038/sj.embor.7400460 · Cited by 223
The structure of plant photosystem I super-complex at 2.8 Å resolution
Mazor, Y., Borovikova, A., & Nelson, N. (2015) · eLife · doi:10.7554/elife.07433 · Cited by 223
Enzymatic Oxygen Scavenging for Photostability without pH Drop in Single-Molecule Experiments
Swoboda, M., Henig, J., Cheng, H., Brugger, D., Haltrich, D., Plumeré, N., & Schlierf, M. (2012) · ACS Nano · doi:10.1021/nn301895c · Cited by 222
On the structure of bacteriochlorophyll molecular aggregates in the chlorosomes of green bacteria. A molecular modelling study
Holzwarth, A. R., & Schaffner, K. (1994) · Photosynthesis Research · doi:10.1007/bf02184163 · Cited by 221
Structure of the LH1–RC complex from Thermochromatium tepidum at 3.0 Å
Niwa, S., Yu, L.-J., Takeda, K., Hirano, Y., Kawakami, T., Wang‐Otomo, Z., & Miki, K. (2014) · Nature · doi:10.1038/nature13197 · Cited by 218
How Nature Harvests Sunlight
Hu, X., & Schulten, K. J. (1997) · Physics Today · doi:10.1063/1.881879 · Cited by 217
Lessons in Fluctuation Correlation Spectroscopy
Digman, M. A., & Gratton, E. (2011) · Annual Review of Physical Chemistry · doi:10.1146/annurev-physchem-032210-103424 · Cited by 214
Pathways of Energy Flow in LHCII from Two-Dimensional Electronic Spectroscopy
Schlau-Cohen, G. S., Calhoun, T. R., Ginsberg, N. S., Read, E. L., Ballottari, M., Bassi, R., van Grondelle, R., & Fleming, G. R. (2009) · The Journal of Physical Chemistry B · doi:10.1021/jp9066586 · Cited by 203
Self-citation
Optical Spectroscopy of Single Impurity Molecules in Solids
Moerner, W. E., & Basché, T. (1993) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199304573 · Cited by 192
Light-harvesting and structural organization of Photosystem II: From individual complexes to thylakoid membrane
Croce, R., & van Amerongen, H. (2011) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2011.02.015 · Cited by 190
Spectral properties of single light-harvesting complexes in bacterial photosynthesis
Saga, Y., Shibata, Y., & Tamiaki, H. (2010) · Journal of Photochemistry and Photobiology C Photochemistry Reviews · doi:10.1016/j.jphotochemrev.2010.02.002 · Cited by 184
Energy Transfer and Charge Separation in Photosystem I: P700 Oxidation Upon Selective Excitation of the Long-Wavelength Antenna Chlorophylls of Synechococcus elongatus
Pålsson, L., Flemming, C., Gobets, B., van Grondelle, R., Dekker, J. P., & Schlodder, E. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77967-6 · Cited by 176
The dynamics of structural deformations of immobilized single light-harvesting complexes
Bopp, M. A., Sytnik, A. I., Howard, T. D., Cogdell, R. J., & Hochstrasser, R. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11271 · Cited by 172
THE FINE STRUCTURE OF GREEN BACTERIA
Cohen-Bazire, G., Pfennig, N., & Kunisawa, R. (1964) · The Journal of Cell Biology · doi:10.1083/jcb.22.1.207 · Cited by 172
Probing single-molecule dynamics photon by photon
Yang, H., & Xie, X. S. (2002) · The Journal of Chemical Physics · doi:10.1063/1.1521154 · Cited by 171
Simple Dark-Field Microscopy with Nanometer Spatial Precision and Microsecond Temporal Resolution
Ueno, H., Nishikawa, S., Iino, R., Tabata, K. V., Sakakihara, S., Yanagida, T., & Noji, H. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2010.01.011 · Cited by 166
Spectroscopy on the B850 Band of Individual Light-Harvesting 2 Complexes of Rhodopseudomonas acidophila I. Experiments and Monte Carlo Simulations
Ketelaars, M., van Oijen, A. M., Matsushita, M. M., Köhler, J. R., Schmidt, J., & Aartsma, T. J. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)76132-2 · Cited by 164
Spectroscopy on the B850 Band of Individual Light-Harvesting 2 Complexes of Rhodopseudomonas acidophila II. Exciton States of an Elliptically Deformed Ring Aggregate
Matsushita, M. M., Ketelaars, M., van Oijen, A. M., Köhler, J. R., Aartsma, T. J., & Schmidt, J. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)76133-4 · Cited by 159
Biomolecular Electronics: Vectorial Arrays of Photosynthetic Reaction Centers
Lee, I., Lee, J. W., & Greenbaum, E. (1997) · Physical Review Letters · doi:10.1103/physrevlett.79.3294 · Cited by 156
Full correlation from picoseconds to seconds by time-resolved and time-correlated single photon detection
Felekyan, S., Kühnemuth, R., Kudryavtsev, V., Sandhagen, C., Becker, W., & Seidel, C. A. M. (2005) · Review of Scientific Instruments · doi:10.1063/1.1946088 · Cited by 156
Molecular architecture of photosynthetic membranes in Rhodobacter sphaeroides: the role of PufX
Siebert, C. A., Pu, Q., Fotiadis, D., Engel, A. H., Hunter, C. N., & Bullough, P. A. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600092 · Cited by 156
Fluorescence Spectral Dynamics of Single LHCII Trimers
Krüger, T. P. J., Novoderezhkin, V. I., Ilioaia, C., & van Grondelle, R. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2010.03.028 · Cited by 155
Direct observation of tiers in the energy landscape of a chromoprotein: A single-molecule study
Hofmann, C., Aartsma, T. J., Michel, H., & Köhler, J. R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2533896100 · Cited by 153
Decay Kinetics and Quantum Yields of Fluorescence in Photosystem I from Synechococcus elongatus with P700 in the Reduced and Oxidized State: Are the Kinetics of Excited State Decay Trap-Limited or Transfer-Limited?
Byrdin, M., Rimke, I., Schlodder, E., Stehlik, D., & Roelofs, T. A. (2000) · Biophysical Journal · doi:10.1016/s0006-3495(00)76353-3 · Cited by 153
Structural Analysis of the Reaction Center Light-harvesting Complex I Photosynthetic Core Complex of Rhodospirillum rubrum Using Atomic Force Microscopy
Fotiadis, D., Pu, Q., Philippsen, A., Bullough, P. A., Engel, A. H., & Hunter, C. N. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310382200 · Cited by 153
Variable LH2 stoichiometry and core clustering in native membranes of Rhodospirillum photometricum
Simon Scheuring, A., Rigaud, J., & Sturgis, J. N. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600429 · Cited by 150
Long‐range organization of bacteriochlorophyll in chlorosomes of Chlorobium tepidum investigated by cryo‐electron microscopy
Oostergetel, G. T., Reus, M., Chew, A. G. M., Bryant, D. A., Boekema, E. J., & Holzwarth, A. R. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.10.045 · Cited by 145
Single photon avalanche diode for single molecule detection
Li, L., & Davis, L. M. (1993) · Review of Scientific Instruments · doi:10.1063/1.1144463 · Cited by 143
Fluorescence Spectroscopy, Exciton Dynamics, and Photochemistry of Single Allophycocyanin Trimers
Ying, L., & Xie, X. S. (1998) · The Journal of Physical Chemistry B · doi:10.1021/jp983227d · Cited by 143
Quantum chemical simulation of excited states of chlorophylls, bacteriochlorophylls and their complexes
Linnanto, J. M., & Korppi‐Tommola, J. (2005) · Physical Chemistry Chemical Physics · doi:10.1039/b513086g · Cited by 142
Watching conformational- and photodynamics of single fluorescent proteins in solution
Goldsmith, R. H., & Moerner, W. E. (2010) · Nature Chemistry · doi:10.1038/nchem.545 · Cited by 142
The Photosynthetic Apparatus of Rhodopseudomonas palustris: Structures and Organization
Simon Scheuring, A., Gonçalves, R. P., Prima, V., & Sturgis, J. N. (2006) · Journal of Molecular Biology · doi:10.1016/j.jmb.2006.01.085 · Cited by 139
Many wheels make light work
Kühlbrandt, W. (1995) · Nature · doi:10.1038/374497a0 · Cited by 138
Controlling Brownian motion of single protein molecules and single fluorophores in aqueous buffer
Cohen, A. E., & Moerner, W. E. (2008) · Optics Express · doi:10.1364/oe.16.006941 · Cited by 137
Statistical Evaluation of Single Nano‐Object Fluorescence
Lippitz, M., Kulzer, F., & Orrit, M. (2005) · ChemPhysChem · doi:10.1002/cphc.200400560 · Cited by 136
High‐aperture cryogenic light microscopy
Gros, M. A. L., McDermott, G., Uchida, M., Knöchel, C., & Larabell, C. A. (2009) · Journal of Microscopy · doi:10.1111/j.1365-2818.2009.03184.x · Cited by 135
PHOTOPHYSICAL PROPERTIES OF PHYCOBILIPROTEINS FROM PHYCOBILISOMES: FLUORESCENCE LIFETIMES, QUANTUM YIELDS, AND POLARIZATION SPECTRA
Grabowski, J., & Gantt, E. (1978) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1978.tb06927.x · Cited by 131
Three-Dimensional Structure of the Rhodobacter sphaeroides RC-LH1-PufX Complex: Dimerization and Quinone Channels Promoted by PufX
Pu, Q., Papiz, M. Z., Jackson, P. J., Brindley, A. A., Ng, I. W., Olsen, J. D., Dickman, M. J., Bullough, P. A., & Hunter, C. N. (2013) · Biochemistry · doi:10.1021/bi4011946 · Cited by 131
FluorMODleaf: A new leaf fluorescence emission model based on the PROSPECT model
Pedrós, R., Goulas, Y., Jacquemoud, S., Louis, J., & Moya, I. (2009) · Remote Sensing of Environment · doi:10.1016/j.rse.2009.08.019 · Cited by 130
Characterization of Chlorobium tepidum Chlorosomes: A Calculation of Bacteriochlorophyll c per Chlorosome and Oligomer Modeling
Montaño, G. A., Bowen, B. P., Belle, J. T. L., Woodbury, N. W., Pizziconi, V. B., & Blankenship, R. E. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74678-5 · Cited by 130
Single molecule spectroscopy: Stark effect of pentacene in p-terphenyl
Wild, U. P., Güttler, F., Pirotta, M., & Renn, A. (1992) · Chemical Physics Letters · doi:10.1016/0009-2614(92)85830-4 · Cited by 130
Tools for correlative cryo-fluorescence microscopy and cryo-electron tomography applied to whole mitochondria in human endothelial cells
van Driel, L. F., Valentijn, J. A., Valentijn, K. M., Koning, R. I., & Koster, A. J. (2009) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2009.07.002 · Cited by 129
Real time imaging of single fluorophores on moving actin with an epifluorescence microscope
Sase, I., Miyata, H., Corrie, J. E. T., Craik, J. S., & Kinosita, K. (1995) · Biophysical Journal · doi:10.1016/s0006-3495(95)79937-4 · Cited by 125
Detectors for single-molecule fluorescence imaging and spectroscopy
Michalet, X., Siegmund, O. H. W., Vallerga, J. V., Jelinsky, P., Millaud, J. E., & Weiss, S. (2007) · Journal of Modern Optics · doi:10.1080/09500340600769067 · Cited by 125
Self-aggregates of bacteriochlorophylls-c, d and e in a light-harvesting antenna system of green photosynthetic bacteria: Effect of stereochemistry at the chiral 3-(1-hydroxyethyl) group on the supramolecular arrangement of chlorophyllous pigments
Miyatake, T., & Tamiaki, H. (2005) · Journal of Photochemistry and Photobiology C Photochemistry Reviews · doi:10.1016/j.jphotochemrev.2005.06.001 · Cited by 122
Single-molecule motions enable direct visualization of biomolecular interactions in solution
Wang, Q., & Moerner, W. E. (2014) · Nature Methods · doi:10.1038/nmeth.2882 · Cited by 121
Resonance energy transfer: Beyond the limits
Andrews, D. L., Curutchet, C., & Scholes, G. D. (2010) · Laser & Photonics Review · doi:10.1002/lpor.201000004 · Cited by 121
Fabrication of a Photoelectronic Device by Direct Chemical Binding of the Photosynthetic Reaction Center Protein to Metal Surfaces
Frolov, L., Rosenwaks, Y., Carmeli, C., & Carmeli, I. (2005) · Advanced Materials · doi:10.1002/adma.200500295 · Cited by 120
Photocurrent of a single photosynthetic protein
Gerster, D., Reichert, J., Bi, H., Barth, J. V., Kaniber, S. M., Holleitner, A. W., Visoly‐Fisher, I., Sergani, S., & Carmeli, I. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.165 · Cited by 120
Robust excitons inhabit soft supramolecular nanotubes
Eisele, D. M., Arias, D. H., Fu, X., Bloemsma, E. A., Steiner, C. P., Jensen, R. A., Rebentrost, P., Eisele, H., Tokmakoff, A., Lloyd, S., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408342111 · Cited by 118
Conformational switching explains the intrinsic multifunctionality of plant light-harvesting complexes
Krüger, T. P. J., Wientjes, E., Croce, R., & van Grondelle, R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105411108 · Cited by 116
Superradiance and Exciton (De)localization in Light-Harvesting Complex II from Green Plants?
Palacios, M. A., de Weerd, F. L., Ihalainen, J. A., van Grondelle, R., & van Amerongen, H. (2002) · The Journal of Physical Chemistry B · doi:10.1021/jp014078t · Cited by 113
Information Bounds and Optimal Analysis of Dynamic Single Molecule Measurements
Watkins, L. P., & Yang, H. (2004) · Biophysical Journal · doi:10.1529/biophysj.103.037739 · Cited by 112
The Reaction Center−LH1 Antenna Complex of Rhodobacter sphaeroides Contains One PufX Molecule Which Is Involved in Dimerization of This Complex
Francia, F., Wang, J., Venturoli, G., Melandri, B. A., Barz, W. P., & Oesterhelt, D. (1999) · Biochemistry · doi:10.1021/bi982891h · Cited by 111
Controlled Disorder in Plant Light-Harvesting Complex II Explains Its Photoprotective Role
Krüger, T. P. J., Ilioaia, C., Johnson, M. P., Ruban, A. V., Papagiannakis, E., Horton, P., & van Grondelle, R. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2012.04.044 · Cited by 111
Development of new photon-counting detectors for single-molecule fluorescence microscopy
Michalet, X., Colyer, R. A., Scalia, G., Ingargiola, A., Lin, R. R., Millaud, J. E., Weiss, S., Siegmund, O. H. W., Tremsin, A. S., Vallerga, J. V., et al. (2012) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0035 · Cited by 111
Ultrafast dynamics of single molecules
Brinks, D., Hildner, R., van Dijk, E. M. H. P., Stefani, F. D., Nieder, J. B., Hernando, J. C., & van Hulst, N. F. (2014) · Chemical Society Reviews · doi:10.1039/c3cs60269a · Cited by 111
Exciton (De)Localization in the LH2 Antenna of Rhodobacter sphaeroides As Revealed by Relative Difference Absorption Measurements of the LH2 Antenna and the B820 Subunit
Novoderezhkin, V. I., Monshouwer, R., & van Grondelle, R. (1999) · The Journal of Physical Chemistry B · doi:10.1021/jp9844415 · Cited by 107
The future is cold: cryo-preparation methods for transmission electron microscopy of cells
Hurbain, I., & Sachse, M. (2011) · Biology of the Cell · doi:10.1042/bc20110015 · Cited by 107
Spectroscopy of Individual Light-Harvesting 2 Complexes of Rhodopseudomonas acidophila: Diagonal Disorder, Intercomplex Heterogeneity, Spectral Diffusion, and Energy Transfer in the B800 Band
van Oijen, A. M., Ketelaars, M., Köhler, J. R., Aartsma, T. J., & Schmidt, J. (2000) · Biophysical Journal · doi:10.1016/s0006-3495(00)76709-9 · Cited by 107
Polarized site-selective fluorescence spectroscopy of the long-wavelength emitting chlorophylls in isolated Photosystem I particles of Synechococcus elongatus
Pålsson, L., Dekker, J. P., Schlodder, E., Monshouwer, R., & van Grondelle, R. (1996) · Photosynthesis Research · doi:10.1007/bf00041014 · Cited by 106
Fluorescence Spectral Fluctuations of Single LH2 Complexes from Rhodopseudomonas acidophila Strain 10050
Rutkauskas, D., Novoderezkhin, V., Cogdell, R. J., & van Grondelle, R. (2004) · Biochemistry · doi:10.1021/bi0497648 · Cited by 104
Fluorescence microscopy of single molecules
Güttler, F., Irngartinger, T., Plakhotnik, T., Renn, A., & Wild, U. P. (1994) · Chemical Physics Letters · doi:10.1016/0009-2614(94)87003-9 · Cited by 103
Single-Molecule Identification of Quenched and Unquenched States of LHCII
Schlau‐Cohen, G. S., Yang, H., Krüger, T. P. J., Xu, P., Gwizdala, M., van Grondelle, R., Croce, R., & Moerner, W. E. (2015) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.5b00034 · Cited by 103
Self-citation
Red antenna states of photosystem I from cyanobacterium Synechococcus elongatus: a spectral hole burning study
Zazubovich, V., Matsuzaki, S., Johnson, T. W., Hayes, J. M., Chitnis, P. R., & Small, G. J. (2002) · Chemical Physics · doi:10.1016/s0301-0104(01)00535-3 · Cited by 102
Dynamics of the Emission Spectrum of a Single LH2 Complex: Interplay of Slow and Fast Nuclear Motions
Novoderezhkin, V. I., Rutkauskas, D., & van Grondelle, R. (2006) · Biophysical Journal · doi:10.1529/biophysj.105.072652 · Cited by 102
Picosecond Kinetics of Light Harvesting and Photoprotective Quenching in Wild-Type and Mutant Phycobilisomes Isolated from the Cyanobacterium Synechocystis PCC 6803
Tian, L., Gwizdala, M., van Stokkum, I. H. M., Koehorst, R. B. M., Kirilovsky, D. L., & van Amerongen, H. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2012.03.008 · Cited by 101
Effects of surface tethering on protein folding mechanisms
Friedel, M., Baumketner, A., & Shea, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601210103 · Cited by 100
Impact of environmentally induced fluctuations on quantum mechanically mixed electronic and vibrational pigment states in photosynthetic energy transfer and 2D electronic spectra
Fujihashi, Y., Fleming, G. R., & Ishizaki, A. (2015) · The Journal of Chemical Physics · doi:10.1063/1.4914302 · Cited by 99
Energetic disorder and the B850-exciton states of individual light-harvesting 2 complexes from Rhodopseudomonas acidophila
Hofmann, C., Aartsma, T. J., & Köhler, J. R. (2004) · Chemical Physics Letters · doi:10.1016/j.cplett.2004.08.020 · Cited by 99
Wide field-of-view lens-free fluorescent imaging on a chip
Coskun, A. F., Su, T., & Özcan, A. (2010) · Lab on a Chip · doi:10.1039/b926561a · Cited by 93
Allophycocyanin and phycocyanin crystal structures reveal facets of phycobilisome assembly
Marx, A., & Adir, N. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2012.11.006 · Cited by 91
Spectroscopy on Single Light-Harvesting Complexes at Low Temperature
Tietz, C., Chekhlov, O. V., Dräbenstedt, A., Schuster, J., & Wrachtrup, J. (1999) · The Journal of Physical Chemistry B · doi:10.1021/jp983599m · Cited by 91
Stochastic theory of inhomogeneous spectroscopic line shapes reinvestigated
Kador, L. (1991) · The Journal of Chemical Physics · doi:10.1063/1.461631 · Cited by 89
Single-Molecule Study of the Electronic Couplings in a Circular Array of Molecules: Light-Harvesting-2 Complex fromRhodospirillum Molischianum
Hofmann, C., Ketelaars, M., Matsushita, M. M., Michel, H., Aartsma, T. J., & Köhler, J. R. (2003) · Physical Review Letters · doi:10.1103/physrevlett.90.013004 · Cited by 88
Rearrangement of light harvesting bacteriochlorophyll homologues as a response of green sulfur bacteria to low light intensities
Borrego, C., & Garcia-Gil, L. J. (1995) · Photosynthesis Research · doi:10.1007/bf00032232 · Cited by 87
Single-molecule spectroscopy reveals photosynthetic LH2 complexes switch between emissive states
Schlau‐Cohen, G. S., Wang, Q., Southall, J., Cogdell, R. J., & Moerner, W. E. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1310222110 · Cited by 86
Self-citation
Efficient Light Harvesting in Dye-Endcapped Conjugated Polymers Probed by Single Molecule Spectroscopy
Becker, K., & Lupton, J. M. (2006) · Journal of the American Chemical Society · doi:10.1021/ja0609405 · Cited by 86
An Adaptive Anti-Brownian Electrokinetic Trap with Real-Time Information on Single-Molecule Diffusivity and Mobility
Wang, Q., & Moerner, W. E. (2011) · ACS Nano · doi:10.1021/nn2014968 · Cited by 85
Investigation on chlorosomal antenna geometries: tube, lamella and spiral-type self-aggregates
Linnanto, J. M., & Korppi‐Tommola, J. (2008) · Photosynthesis Research · doi:10.1007/s11120-008-9304-3 · Cited by 84
Atomic force microscopy of the bacterial photosynthetic apparatus: plain pictures of an elaborate machinery
Simon Scheuring, A., & Sturgis, J. N. (2009) · Photosynthesis Research · doi:10.1007/s11120-009-9413-7 · Cited by 83
Single-Molecule Pump-Probe Detection Resolves Ultrafast Pathways in Individual and Coupled Quantum Systems
van Dijk, E. M. H. P., Hernando, J. C., García-López, J. J., Crego‐Calama, M., Reinhoudt, D. N., Kuipers, L., Parajo, M. F. G., & van Hulst, N. F. (2005) · Physical Review Letters · doi:10.1103/physrevlett.94.078302 · Cited by 83
Single-Particle Tracking Photoactivated Localization Microscopy for Mapping Single-Molecule Dynamics
Manley, S., Gillette, J. M., & Lippincott‐Schwartz, J. (2010) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(10)75005-9 · Cited by 82
Organization of Bacteriochlorophylls in Individual Chlorosomes from Chlorobaculum tepidum Studied by 2-Dimensional Polarization Fluorescence Microscopy
Tian, Y., Camacho, R., Thomsson, D., Reus, M., Holzwarth, A. R., & Scheblykin, I. G. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2019959 · Cited by 80
Determination of the topography and biometry of chlorosomes by atomic force microscopy
Martínez-Planells, A., Arellano, J. B., Borrego, C., López‐Iglesias, C., Gich, F. B., & Garcia-Gil, L. J. (2002) · Photosynthesis Research · doi:10.1023/a:1014955614757 · Cited by 78
A maximum likelihood estimator to distinguish single molecules by their fluorescence decays
Enderlein, J., Goodwin, P. M., Orden, A. K. V., Ambrose, W. P., Erdmann, R., & Keller, R. A. (1997) · Chemical Physics Letters · doi:10.1016/s0009-2614(97)00409-0 · Cited by 76
Polarization Portraits of Single Multichromophoric Systems: Visualizing Conformation and Energy Transfer
Mirzov, O., Bloem, E., Hania, P. R., Thomsson, D., Lin, H., & Scheblykin, I. G. (2009) · Small · doi:10.1002/smll.200801168 · Cited by 74
Disentangling the low-energy states of the major light-harvesting complex of plants and their role in photoprotection
Krüger, T. P. J., Ilioaia, C., Johnson, M. P., Ruban, A. V., & van Grondelle, R. (2014) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2014.02.014 · Cited by 74
Single Molecule Spectroscopy on the Light-Harvesting Complex II of Higher Plants
Tietz, C., Jelezko, F., Gerken, U., Schuler, S., Schubert, A., Rogl, H., & Wrachtrup, J. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)75722-0 · Cited by 73
Single-Molecule Spectroscopy Reveals that Individual Low-Light LH2 Complexes from Rhodopseudomonas palustris 2.1.6. Have a Heterogeneous Polypeptide Composition
Brotosudarmo, T. H. P., Kunz, R., Böhm, P. S., Gardiner, A. T., Moulisová, V., Cogdell, R. J., & Köhler, J. R. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2009.06.034 · Cited by 73
Fluorescence microscopy in superfluid helium: Single molecule imaging
Jasny, J., Sepioł, J., Irngartinger, T., Traber, M., Renn, A., & Wild, U. P. (1996) · Review of Scientific Instruments · doi:10.1063/1.1146868 · Cited by 73
Fluorescence Intermittency from the Main Plant Light-Harvesting Complex: Sensitivity to the Local Environment
Krüger, T. P. J., Ilioaia, C., Valkūnas, L., & van Grondelle, R. (2011) · The Journal of Physical Chemistry B · doi:10.1021/jp109833x · Cited by 73
Spectroscopy of Single Light-Harvesting Complexes from Purple Photosynthetic Bacteria at 1.2 K
van Oijen, A. M., Ketelaars, M., Köhler, J. R., Aartsma, T. J., & Schmidt, J. (1998) · The Journal of Physical Chemistry B · doi:10.1021/jp9830629 · Cited by 72
Antenna complexes protect Photosystem I from Photoinhibition
Alboresi, A., Ballottari, M., Hienerwadel, R., Giacometti, G. M., & Morosinotto, T. (2009) · BMC Plant Biology · doi:10.1186/1471-2229-9-71 · Cited by 71
Red Chlorophyll a Antenna States of Photosystem I of the Cyanobacterium Synechocystis sp. PCC 6803
Hayes, J. M., Matsuzaki, S., Rätsep, M., & Small, G. J. (2000) · The Journal of Physical Chemistry B · doi:10.1021/jp000447u · Cited by 70
Models and measurements of energy-dependent quenching
Zaks, J., Amarnath, K., Sylak-Glassman, E. J., & Fleming, G. R. (2013) · Photosynthesis Research · doi:10.1007/s11120-013-9857-7 · Cited by 69
Looking into the energy landscape of myoglobin
Leeson, D. T., & Wiersma, D. A. (1995) · Nature Structural Biology · doi:10.1038/nsb1095-848 · Cited by 68
Absorption Linear Dichroism Measured Directly on a Single Light-Harvesting System: The Role of Disorder in Chlorosomes of Green Photosynthetic Bacteria
Furumaki, S., Vácha, F., Habuchi, S., Tsukatani, Y., Bryant, D. A., & Vácha, M. (2011) · Journal of the American Chemical Society · doi:10.1021/ja111475z · Cited by 68
Conformational regulation of charge recombination reactions in a photosynthetic bacterial reaction center
Katona, G., Snijder, A., Gourdon, P. E., Andréasson, U., Hansson, Ö., Andréasson, L., & Neutze, R. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb948 · Cited by 67
Bio-inspired artificial light-harvesting antennas for enhancement of solar energy capture in dye-sensitized solar cells
Odobel, F., Pellegrin, Y., & Warnan, J. (2013) · Energy & Environmental Science · doi:10.1039/c3ee24229c · Cited by 65
Spectroscopic elucidation of uncoupled transition energies in the major photosynthetic light-harvesting complex, LHCII
Schlau‐Cohen, G. S., Calhoun, T. R., Ginsberg, N. S., Ballottari, M., Bassi, R., & Fleming, G. R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006230107 · Cited by 65
Self-citation
Single-Molecule Spectroscopy on Photosystem I Pigment−Protein Complexes
Jelezko, F., Tietz, C., Gerken, U., Wrachtrup, J., & Bittl, R. (2000) · The Journal of Physical Chemistry B · doi:10.1021/jp001332t · Cited by 64
Controlling Light Harvesting with Light
Gwizdala, M., Berera, R., Kirilovsky, D., van Grondelle, R., & Krüger, T. P. J. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b04811 · Cited by 60
Analysis of spherical aberration of a water immersion objective: application to specimens with refractive indices 1.33–1.40
Wan, D., Rajadhyaksha, M. M., & Webb, R. H. (2000) · Journal of Microscopy · doi:10.1046/j.1365-2818.2000.00635.x · Cited by 59
Fluorescence spectra of single pentacene molecules in p-terphenyl at 1.7 K
Fleury, L., Tamarat, P., Lounis, B., Bernard, J., & Orrit, M. (1995) · Chemical Physics Letters · doi:10.1016/0009-2614(95)00185-7 · Cited by 59
Dynamic Disorder in Single-Enzyme Experiments: Facts and Artifacts
Terentyeva, T. G., Engelkamp, H., Rowan, A. E., Komatsuzaki, T., Hofkens, J., Li, C., & Blank, K. G. (2011) · ACS Nano · doi:10.1021/nn203669r · Cited by 59
Classification of image data in conjugate representation spaces
Borland, L., & van Heel, M. (1990) · Journal of the Optical Society of America A · doi:10.1364/josaa.7.000601 · Cited by 59

Research works printed but not linked: 6

10.1562/0031-8655(2002)0750433SHISLH2.0.CO2 · DOI
Alexa Fluor Dyes Spanning the Visible and Infrared Spectrum
Denvir D. J., 2002, International Symposium on Biomedical Optics, 502
Vallerga J. V., 2008, SPIE Astronomical Telescopes + Instrumentation, 702115
Ohnuki T., 2006, Biomedical Optics 2006, 60920P
Gulinatti A., 2011, SPIE Defense, Security, and Sensing, 803302

Sorted by citations

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Li, M., Shi, Q., Song, N., Xiao, Y., Wang, L., Chen, Z., & James, T. D. (2023) · Chemical Society Reviews · doi:10.1039/d2cs00683a · Cited by 316
The future of quantum biology
Marais, A., Adams, B., Ringsmuth, A. K., Ferretti, M., Gruber, J. M., Hendrikx, R., Schuld, M., Smith, S. L., Sinayskiy, I., Krüger, T. P. J., et al. (2018) · Journal of The Royal Society Interface · doi:10.1098/rsif.2018.0640 · Cited by 274
Delocalized excitons in natural light-harvesting complexes
Jang, S., & Mennucci, B. (2018) · Reviews of Modern Physics · doi:10.1103/revmodphys.90.035003 · Cited by 239
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Park, Y., Jin, S., Noda, I., & Jung, Y. M. (2018) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2018.04.099 · Cited by 106

See all 120

Authors: Kondo, T., Chen, W. J., & Schlau-Cohen, G. S.
Affiliations: Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge Massachusetts 02139, United States
Massachusetts Institute of Technology (US)
ORCID: Chen, Wei Jia
Schlau-Cohen, Gabriela S.
Venue: Chemical Reviews
Publisher: American Chemical Society (ACS)
Published: 2017-01-10
Volume: 117
Issue: 2
Pages: 860-898
ISSN: 0009-2665 (ISSN-L)
1520-6890
DOI: 10.1021/acs.chemrev.6b00195
OpenAlex: W2568620643
Cited by: 120
References: 320
Citations by year: 2026: 6 · 2025: 13 · 2024: 16 · 2023: 10 · 2022: 16 · 2021: 11 · 2020: 13 · 2019: 10 · 2018: 16 · 2017: 9
FWCI: 0.87
Type: journal article
Language: en
Open access: green
www.osti.gov
Locations: Chemical Reviews (publishedVersion)
PubMed (publishedVersion)
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
Funders: Richard and Susan Smith Family Foundation (Excellence in Biomedical Research Award)
Basic Energy Sciences (Center for Excitonics/DE-SC0001088)
Topics: Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Spectroscopy and Quantum Chemical Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Photochemistry and Electron Transfer Studies
Keywords: photosynthesis, light-harvesting complexes, single-molecule fluorescence spectroscopy, pigment-protein complexes, structural heterogeneity, energetic heterogeneity, functional heterogeneity, thermal fluctuations, energy transport, charge separation, reaction center, quantum efficiency, low-light adaptation
MeSH terms: Photosynthesis, Pigments, Biological, Proteins, Spectrometry, Fluorescence

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