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Nonclassical Routes for Amide Bond Formation

de Figueiredo, Renata Marcia, Suppo, Jean-Simon, Campagne, Jean-Marc·2016·Chemical Reviews

Abstract

The present review offers an overview of nonclassical (e.g., with no pre- or in situ activation of a carboxylic acid partner) approaches for the construction of amide bonds. The review aims to comprehensively discuss relevant work, which was mainly done in the field in the last 20 years. Organization of the data follows a subdivision according to substrate classes: catalytic direct formation of amides from carboxylic and amines ( section 2 ); the use of carboxylic acid surrogates ( section 3 ); and the use of amine surrogates ( section 4 ). The ligation strategies (NCL, Staudinger, KAHA, KATs, etc.) that could involve both carboxylic acid and amine surrogates are treated separately in section 5 .

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Metadata

Authors
de Figueiredo, R. M., Suppo, J.-S., & Campagne, J.-M.
Venue
Chemical Reviews
Published
2016-09-22
Volume
116
Issue
19
Pages
12029-12122
ISSN
  • 0009-2665 (ISSN-L)
  • 1520-6890
OpenAlex
W2523045592
Cited by
978
References
5
FWCI
5.92
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Nonclassical Routes for Amide Bond Formation. https://app.cochat.ai/papers/10.1021/acs.chemrev.6b00237
The paper
de Figueiredo, R. M., Suppo, J.-S., & Campagne, J.-M. (2016). Nonclassical Routes for Amide Bond Formation. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.6b00237

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.