The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Amide Bond Formation Strategies: Latest Advances on a Dateless Transformation
Open accessAbstract
The synthesis of amides remains one of the most important transformations and it is one of the more frequently performed reactions. In the pharmaceutical industry, the formation of the amide group is pivotal and among the more important transformations in the design of the synthetic plan. This review presents an overview of only very recent contributions, published in the last three years, to highlight the latest progress in this “dateless” reaction, with a special focus on metal‐free methodologies. New, more efficient and/or greener stoichiometric methods, as well as catalytic strategies, have been discussed, either for the “classic” coupling approach between an amine and a carboxylic acid (or its activated equivalent) or for more innovative approaches, mainly involving oxidation procedures to generate amides starting from amines.
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Cites
Deep Eutectic Solvents (DESs) and Their Applications
Smith, E. L., Abbott, A. P., & Ryder, K. S. (2014) · Chemical Reviews · doi:10.1021/cr300162p · Cited by 7,378
Deep eutectic solvents: syntheses, properties and applications
Zhang, Q., De Oliveira Vigier, K., Royer, S., & Jérôme, F. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35178a · Cited by 4,899
Mechanochemistry: opportunities for new and cleaner synthesis
James, S. L., Adams, C. J., Bolm, C., Braga, D., Collier, P., Friščić, T., Grepioni, F., Harris, K. D. M., Hyett, G., Jones, W., et al. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15171a · Cited by 3,056
CHEM21 selection guide of classical- and less classical-solvents
Prat, D., Wells, A., Hayler, J., Sneddon, H., McElroy, C. R., Abou-Shehada, S., & Dunn, P. J. (2016) · Green Chemistry · doi:10.1039/c5gc01008j · Cited by 2,215
Rethinking amide bond synthesis
Pattabiraman, V. R., & Bode, J. W. (2011) · Nature · doi:10.1038/nature10702 · Cited by 2,164
The E factor 25 years on: the rise of green chemistry and sustainability
Sheldon, R. A. (2017) · Green Chemistry · doi:10.1039/c6gc02157c · Cited by 1,525
Metrics of Green Chemistry and Sustainability: Past, Present, and Future
Sheldon, R. A. (2018) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.7b03505 · Cited by 1,292
Nonclassical Routes for Amide Bond Formation
de Figueiredo, R. M., Suppo, J.-S., & Campagne, J.-M. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00237 · Cited by 978
Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals
Dunetz, J. R., Magano, J., & Weisenburger, G. A. (2016) · Organic Process Research & Development · doi:10.1021/op500305s · Cited by 819
Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited
Bryan, M. C., Dunn, P. J., Entwistle, D., Gallou, F., Koenig, S. G., Hayler, J. D., Hickey, M. R., Hughes, S., Kopach, M. E., Moine, G., et al. (2018) · Green Chemistry · doi:10.1039/c8gc01276h · Cited by 614
Cited by
Kekessie, I., Wegner, K., Martinez, I., Kopach, M. E., White, T. D., Tom, J. K., Kenworthy, M. N., Gallou, F., Lopez, J., Koenig, S. G., et al. (2024) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.3c01494 · Cited by 149
Metadata
- Authors
- Massolo, E., Pirola, M., & Benaglia, M.
- Venue
- European Journal of Organic Chemistry
- Publisher
- Wiley
- Published
- 2020-05-04
- Volume
- 2020
- Issue
- 30
- Pages
- 4641-4651
- ISSN
- 1099-0690 (ISSN-L)
- 1434-193X
- OpenAlex
- W3012303473
- Cited by
- 294
- References
- 47
- FWCI
- 13.23
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
