The DOI matches its Crossref record; 379 of the 379 references it cites were found in a registry or an index.
New Generation Cadmium-Free Quantum Dots for Biophotonics and Nanomedicine
Open accessAbstract
This review summarizes recent progress in the design and applications of cadmium-free quantum dots (Cd-free QDs), with an emphasis on their role in biophotonics and nanomedicine. We first present the features of Cd-free QDs and describe the physics and emergent optical properties of various types of Cd-free QDs whose applications are discussed in subsequent sections. Selected specific QD systems are introduced, followed by the preparation of these Cd-free QDs in a form useful for biological applications, including recent advances in achieving high photoluminescence quantum yield (PL QY) and tunability of emission color. Next, we summarize biophotonic applications of Cd-free QDs in optical imaging, photoacoustic imaging, sensing, optical tracking, and photothermal therapy. Research advances in the use of Cd-free QDs for nanomedicine applications are discussed, including drug/gene delivery, protein/peptide delivery, image-guided surgery, diagnostics, and medical devices. The review then considers the pharmacokinetics and biodistribution of Cd-free QDs and summarizes current studies on the in vitro and in vivo toxicity of Cd-free QDs. Finally, we provide perspectives on the overall current status, challenges, and future directions in this field.
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Cites
3 retracted
Gui, R., Wan, A., Liu, X., Yuan, W., & Jin, H. (2014) · Nanoscale · doi:10.1039/c4nr00282b · Cited by 87
RetractedSynthesis of near-Infrared Quantum Dots in Cultured Cancer Cells
Tan, L., Wan, A., & Li, H. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am404534v · Cited by 58
RetractedTan, L., Wan, A., Zhao, T., Huang, R., & Li, H. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am5015088 · Cited by 49
RetractedUnderstanding biophysicochemical interactions at the nano–bio interface
Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., Klaessig, F., Castranova, V., & Thompson, M. (2009) · Nature Materials · doi:10.1038/nmat2442 · Cited by 7,083
Brus, L. E. (1984) · The Journal of Chemical Physics · doi:10.1063/1.447218 · Cited by 5,046
Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells
Chithrani, B. D., Ghazani, A. A., & Chan, W. C. W. (2006) · Nano Letters · doi:10.1021/nl052396o · Cited by 4,879
Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
Delivering nanomedicine to solid tumors
Jain, R. K., & Stylianopoulos, T. (2010) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2010.139 · Cited by 3,180
Hydrothermal Route for Cutting Graphene Sheets into Blue‐Luminescent Graphene Quantum Dots
Pan, D., Zhang, J., Li, Z., & Wu, M. (2010) · Advanced Materials · doi:10.1002/adma.200902825 · Cited by 2,853
Second window for in vivo imaging
Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848
Cited by
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery
Panwar, N., Soehartono, A. M., Chan, K. K., Zeng, S., Xu, G., Qu, J., Coquet, P., Yong, K.-T., & Chen, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00099 · Cited by 555
Self-citationSemiconductor Quantum Dots: An Emerging Candidate for CO2 Photoreduction
Wu, H., Li, X., Tung, C., & Wu, L. (2019) · Advanced Materials · doi:10.1002/adma.201900709 · Cited by 486
Application of semiconductor quantum dots in bioimaging and biosensing
Martynenko, I. V., Litvin, A. P., Purcell-Milton, F., Baranov, A. V., Fedorov, A. V., & Gun'ko, Y. K. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb01425b · Cited by 382
A phosphorescent probe for in vivo imaging in the second near-infrared window
Chang, B., Li, D., Ren, Y., Qu, C., Shi, X., Liu, R., Liu, H., Tian, J., Hu, Z., Sun, T., et al. (2021) · Nature Biomedical Engineering · doi:10.1038/s41551-021-00773-2 · Cited by 195
Li, Y., Zhang, P., Tang, W., McHugh, K. J., Kershaw, S. V., Jiao, M., Huang, X., Kalytchuk, S., Perkinson, C. F., Yue, S., et al. (2022) · ACS Nano · doi:10.1021/acsnano.2c01153 · Cited by 98
Metadata
- Authors
- Xu, G., Zeng, S., Zhang, B., Swihart, M. T., Yong, K.-T., & Prasad, P. N.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-09-22
- Volume
- 116
- Issue
- 19
- Pages
- 12234-12327
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2473477171
- Cited by
- 587
- References
- 379
- FWCI
- 1.72
- Type
- journal article
- Language
- en
- Open access
- green
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- Xu, G., Zeng, S., Zhang, B., Swihart, M. T., Yong, K.-T., & Prasad, P. N. (2016). New Generation Cadmium-Free Quantum Dots for Biophotonics and Nanomedicine. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.6b00290
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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