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Cited by 720

The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.

Single-Molecule Chemistry with Surface- and Tip-Enhanced Raman Spectroscopy

Zrimsek, Alyssa B., Chiang, Naihao, Mattei, Michael, Zaleski, Stephanie, McAnally, Michael O., Chapman, Craig T., Henry, Anne-Isabelle, Schatz, George C., Van Duyne, Richard P.·2017·Chemical Reviews
DOI 10.1021/acs.chemrev.6b00552
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Abstract

Single-molecule (SM) surface-enhanced Raman spectroscopy (SERS) and tip-enhanced Raman spectroscopy (TERS) have emerged as analytical techniques for characterizing molecular systems in nanoscale environments. SERS and TERS use plasmonically enhanced Raman scattering to characterize the chemical information on single molecules. Additionally, TERS can image single molecules with subnanometer spatial resolution. In this review, we cover the development and history of SERS and TERS, including the concept of SERS hot spots and the plasmonic nanostructures necessary for SM detection, the past and current methodologies for verifying SMSERS, and investigations into understanding the signal heterogeneities observed with SMSERS. Moving on to TERS, we cover tip fabrication and the physical origins of the subnanometer spatial resolution. Then, we highlight recent advances of SMSERS and TERS in fields such as electrochemistry, catalysis, and SM electronics, which all benefit from the vibrational characterization of single molecules. SMSERS and TERS provide new insights on molecular behavior that would otherwise be obscured in an ensemble-averaged measurement.

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Crossref · 10.1021/acs.chemrev.6b00552

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Metadata

Authors
Zrimsek, A. B., Chiang, N., Mattei, M., Zaleski, S., McAnally, M. O., Chapman, C. T., Henry, A.-I., Schatz, G. C., & Van Duyne, R. P.
Venue
Chemical Reviews
Publisher
American Chemical Society (ACS)
Published
2016-12-08
Volume
117
Issue
11
Pages
7583-7613
ISSN
  • 0009-2665 (ISSN-L)
  • 1520-6890
DOI
10.1021/acs.chemrev.6b00552
OpenAlex
W2560055168
Cited by
720
References
153
FWCI
1.71
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Single-Molecule Chemistry with Surface- and Tip-Enhanced Raman Spectroscopy. https://app.cochat.ai/papers/10.1021/acs.chemrev.6b00552
The paper
Zrimsek, A. B., Chiang, N., Mattei, M., Zaleski, S., McAnally, M. O., Chapman, C. T., Henry, A.-I., Schatz, G. C., & Van Duyne, R. P. (2017). Single-Molecule Chemistry with Surface- and Tip-Enhanced Raman Spectroscopy. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.6b00552

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.