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Cited by 316

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Per- and Polyfluoroalkyl Substances (PFAS) in Breast Milk: Concerning Trends for Current-Use PFAS

Zheng, Guomao, Schreder, Erika, Dempsey, Jennifer C., Uding, Nancy, Chu, Valerie, Andres, Gabriel, Sathyanarayana, Sheela, Salamova, Amina·2021·Environmental Science & Technology

Abstract

This is the first study in the last 15 years to analyze per- and polyfluoroalkyl substances (PFAS) in breast milk collected from mothers ( n = 50) in the United States, and our findings indicate that both legacy and current-use PFAS now contaminate breast milk, exposing nursing infants. Breast milk was analyzed for 39 PFAS, including 9 short-chain and 30 long-chain compounds, and 16 of these PFAS were detected in 4–100% of the samples. The ∑PFAS concentration in breast milk ranged from 52.0 to 1850 pg/mL with a median concentration of 121 pg/mL. Perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) were the most abundant PFAS in these samples (medians 30.4 and 13.9 pg/mL, respectively). Two short-chain PFAS, including perfluoro- n -hexanoic acid (PFHxA, C6) and perfluoro- n -heptanoic acid (PFHpA, C7), were detected in most of the samples with median concentrations of 9.69 and 6.10 pg/mL, respectively. Analysis of the available breast milk PFAS data from around the world over the period of 1996–2019 showed that while the levels of the phased-out PFOS and PFOA have been declining with halving times of 8.1 and 17 years, respectively, the detection frequencies of current-use short-chain PFAS have been increasing with a doubling time of 4.1 years.

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Metadata

Authors
Zheng, G., Schreder, E., Dempsey, J. C., Uding, N., Chu, V., Andres, G., Sathyanarayana, S., & Salamova, A.
Venue
Environmental Science & Technology
Published
2021-05-13
Volume
55
Issue
11
Pages
7510-7520
ISSN
  • 0013-936X (ISSN-L)
  • 1520-5851
OpenAlex
W3160202374
Cited by
316
References
95
FWCI
18.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Per- and Polyfluoroalkyl Substances (PFAS) in Breast Milk: Concerning Trends for Current-Use PFAS. https://app.cochat.ai/papers/10.1021/acs.est.0c06978
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Zheng, G., Schreder, E., Dempsey, J. C., Uding, N., Chu, V., Andres, G., Sathyanarayana, S., & Salamova, A. (2021). Per- and Polyfluoroalkyl Substances (PFAS) in Breast Milk: Concerning Trends for Current-Use PFAS. Environmental Science & Technology. https://doi.org/10.1021/acs.est.0c06978

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